Best Large Grants for Nonprofit Organizations in Missouri

The World Trade Center Scholarship in New Jersey provides financial support to dependent children and surviving spouses of residents who lost their lives in the September 11 attacks. Administered by HESAA, this scholarship covers tuition, fees, and other educational costs at eligible institutions. Applicants must be full-time students and maintain satisfactory academic progress. The award amount varies each year based on funding and need, ensuring that assistance is available to those who have lost financial support due to these tragic events.

About Us

Our mission is to serve as a catalyst in maximizing the skills and creativity of educators at the K-12 levels and in cultivating pioneering approaches to teaching that result in dynamic student learning.

The McCarthey Dressman Education Foundation sponsors proposals that enhance student learning and educational quality, paying particular attention to those that best serve the at-risk and under-funded, including:

• Curriculum that excites and challenges
• Inquiry projects that promote reflection and growth
• After-school programs that enrich and inspire

The Foundation partners with individuals to expand educational opportunities for America’s youth that inspire students by nurturing their curiosity about the world and their place in it. Funding includes scholarships that provide far more than just tuition and books; grants that benefit the lives of more than just those who receive them; and results that reach far beyond the classroom in which the projects are introduced.

Student Teaching Scholarships/Mentoring

Designed to instill a lifelong, passionate commitment to education and learning at the highest level, McCarthey Dressman scholarships offer financial and mentoring support to educators who will be student teaching in their final year of a qualified teacher education program. Foundation mentors offer one-on-one guidance and attention to nurture the next generation of teachers. Scholarship recipients acquire and strengthen exemplary teaching practices that promote learning by their own students.

The Foundation awards one-year scholarships in the amount of $6,000 each to college students enrolled in teacher education programs at New Mexico State University; the University of California, Santa Cruz; The University of Texas at Austin; and Stephen F. Austin State University.

Consider applying for this scholarship if... 

• you are interested in maximizing your student teaching experience
• you believe that working with a mentor would add to your training experience
• you can provide documentation of financial need for the year in which you will be student teaching

The Lingnan W.T. Chan Fellowship Program provides transformative educational experiences for Chinese students in the U.S. through service learning and intercultural exchange. Inspired by Professor Wing-Tsit Chan, this program emphasizes a commitment to service, personal growth, and leadership development. Fellows engage with non-profit organizations, gaining practical experience while living with American families and participating in seminars and reflection meetings, fostering intercultural understanding and professional skills.

About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.About Comfort Kits and Grab N' Go ProgramIn addition to our direct outreach, the DVNF also supports like-minded organizations that share our commitment to serving veterans. Approved organizations can apply to receive Comfort Kits for distribution to veterans in their communities. These kits are designed to meet the unique needs of veterans and offer critical support where they are needed most.

About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.

About Grants to Provide Stability (GPS) ProgramThe Disabled Veterans National Foundation’s GPS (Grants to Provide Stability) Program is a grant program for veterans who find themselves in temporary financial setback. DVNF will provide up to $1,000 (not guaranteed) to help eligible veterans pay for rent or mortgage and essential utilities such as water or electricity. Applications are open on a monthly basis. Please note that each veteran can only be approved once per fiscal year (October – September).

The Arnold O. Beckman Postdoctoral Fellowship offers researchers the opportunity to advance their studies in Chemical Sciences or Chemical Instrumentation. This program supports innovative research within fundamental chemistry and the development of new instrumentation. Candidates must be U.S. citizens or permanent residents, or DACA recipients, with a PhD in the chemical sciences anticipated by May 1, 2026. Mentorship from a qualified institution is required, fostering independent research capabilities in a collaborative environment.

The Carnegie-Whitney Grant, established by Andrew Carnegie in 1902, supports the creation of bibliographical aids for American libraries. Grants cover the preparation costs of reading lists and indexes, enhancing access to library resources. Eligibility requires projects to stimulate library use and be broadly appealing, with a focus on national distribution. Notably, completed works and projects under contract are ineligible. The fund encourages innovation in library resource development, welcoming applications from individuals and organizations.

The Anne S. Chatham Fellowship in Medicinal Botany, funded by the Garden Club of America, aims to protect and expand knowledge of medicinal plants. It offers a $4,500 grant to support Ph.D. students and recent graduates in pursuing essential research that may otherwise be inaccessible. This initiative not only fosters botanical research but also contributes to the development of therapies that enhance patient quality of life and potentially save lives.

The Opportunities for Collaborative Research at the NIH Clinical Center aims to foster high-quality translational research partnerships between NIH intramural and extramural investigators. This program supports projects that bridge basic biological discoveries with clinical applications, ultimately enhancing patient-centric research. By facilitating collaborations, the program seeks to accelerate scientific advancements leading to improved health outcomes through innovative therapeutic interventions and diagnostic strategies.

The Tipgoomoogus Memorial Trust Grant supports organizations dedicated to the care and comfort of small household pets, including dogs, cats, and birds. Founded by Thomas and Ellen Fallon, the trust primarily funds New Jersey-based charities that qualify as 501(c)(3) organizations. Applications are accepted year-round, with a submission deadline of April 30 for annual review. The foundation prefers to assist animal shelters and dog pounds, while excluding funding for salaries or animals raised for commercial or research purposes.

The PEDIGREE Foundation: Dogs Rule Grant aims to support innovative initiatives that enhance dog adoption rates in the U.S. Established in 2008, the foundation focuses on organizations that improve care for dogs in shelters and rescues. Grants are available to 501(c)(3) organizations with a commitment to creating best practices for increasing adoptions. The program requires a manual or toolkit to be developed and shared with the animal welfare community to ensure sustainability and broader impact.

The Dr. A. Jean Ayres Doctoral Candidate Scholarship, funded by The American Occupational Therapy Foundation, supports emerging OT scientists focusing on sensory integration and processing research. This $5,000 scholarship aids doctoral candidates in conducting impactful studies, contributing to the field of occupational therapy and enhancing care delivery. Eligible applicants must be enrolled in a doctoral program, have defended their dissertation proposal, and conduct research at a US institution. The scholarship emphasizes the importance of evidence-based practices for underserved communities.

The Dr. Carolyn Baum Cognitive Function in Daily Life Mentor Award, funded by the American Occupational Therapy Foundation, supports mid-to senior-level occupational therapy researchers mentoring assistant professors or post-doctoral fellows. This $10,000 stipend aims to enhance understanding of cognition's role in daily life through research. Dr. Carolyn Baum, a pioneer in the field, inspires this initiative, promoting the advancement of functional cognition in occupational therapy.

The Learning & Leadership Grants support educators in enhancing their professional development and leadership skills. With funding up to $5,000, these grants are available for individual educators or groups pursuing high-quality learning experiences such as conferences and seminars. Eligible applicants must be current members of the National Education Association. These grants aim to empower educators to implement innovative practices in their classrooms, ultimately benefiting students and the educational community.

The Ladies’ Branch of the New Bedford Port Society Scholarship, managed by the SouthCoast Community Foundation, supports students with familial ties to the sea or descendants of seamen. This scholarship aims to promote education in maritime-related fields. Eligible applicants must reside in specific SouthCoast communities or plan to pursue maritime sciences. Since its inception, the Foundation has distributed over $50 million to enhance the region's educational, humanitarian, and cultural landscape.

The ETC Equipment Grant supports U.S.-based non-profit organizations, schools, and government entities by providing essential lighting technology. This initiative, part of ETC's Light the Way Program, aims to enhance training in performance arts through equipment grants. Recipients can choose from a variety of packages, including consoles and LED fixtures, tailored to their facility's needs. ETC also offers training for all awarded equipment, ensuring recipients maximize the impact of their grants.

The Folded Flag Foundation offers educational scholarships for college-bound spouses and children of U.S. military members and government employees who died due to combat-related incidents. This program supports tuition, fees, and living expenses for eligible applicants under 26 years old. It aims to assist families in achieving educational goals while navigating the challenges of loss. The scholarships cover various educational expenses, ensuring access to both college and technical training opportunities.

The General Montgomery (Monty) C. Meigs Scholarship, offered by the Folded Flag Foundation, honors individuals who embody Monty Meigs' exceptional leadership and dedication. This scholarship is available to high school and college students who display academic excellence and commitment to service. Applicants must submit academic records, a recommendation letter, and a personal essay. Designed to support the next generation of leaders, this scholarship reflects Monty's legacy of service and achievement.

The Indian Student Conference Scholarship offers two annual awards of $500 each to Native American students pursuing undergraduate, M.A., or Ph.D. degrees. This funding aims to alleviate the financial burden of attending the annual Western History Association conference. Recipients will also receive coverage for conference registration and tickets to various receptions and luncheons, promoting participation in discussions about western history and fostering academic collaboration.

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The Enbridge Safe Community First Responder Program is designed to support emergency response organizations across Canada and the U.S. by providing grants for safety equipment, training, and educational programs. Launched in 2002, it has invested over $22 million in enhancing community safety. Eligible organizations include fire departments and medical services located near Enbridge operations. Grants typically range from $1,000 to $10,000, helping improve the capabilities of first responders in rural and underserved areas.

Incyte Corporation offers an Independent Medical Education Grant to support innovative educational initiatives aimed at improving patient outcomes. This funding is available to organizations committed to delivering evidence-based education to healthcare professionals. Eligible activities may include live symposia, grand rounds, fellowships, and web-based programs. Organizations must enter into a written agreement with Incyte to receive funding. Note that new request submissions will be temporarily unavailable from November 21, 2025, to January 2026.

The Rural Summer Legal Corps (RSLC) addresses the legal service gap in rural U.S. communities by placing law students in civil legal aid organizations. This initiative, in partnership with Equal Justice Works and the Legal Services Corporation, allows 50 Student Fellows to engage in impactful projects, such as disaster response and housing issues, while gaining practical experience over eight to ten weeks. Participants receive a stipend of $7,000, enhancing their skills and supporting underserved populations.

The Regional Public Interest Awards recognize eight outstanding law students annually for their dedication to public interest law. Selected by the Equal Justice Works National Advisory Committee, each recipient demonstrates exceptional commitment through volunteer work, internships, and clinics. Awardees receive a $250 cash prize and a commemorative plaque, celebrating their significant contributions to their communities and the legal profession.

Stars, Stripes & Skilled Trades

General Motors invites eligible 501(c)(3) nonprofit organizations to submit proposals for Stars, Stripes & Skilled Trades, a workforce development initiative designed to support veterans, transitioning service members, and military-connected family members—including spouses—in building lasting careers in manufacturing, automotive, and skilled trades. GM is seeking scalable, results-driven programs that create clear pathways to quality careers while recognizing the experience and leadership that veterans and military families bring to American industry. 

We're looking for existing initiatives that:

• Serve career-transitioning service members, veterans, and military-connected family members
• Provide industry-recognized training, certifications, or credentials
• Connect participants to mentorships, quality jobs, and long-term career pathways in manufacturing, automotive technician roles, or skilled trades.

Grant Range

• $100,000 | $250,000 | $500,000

The Design-Your-Own Fellowship by Equal Justice Works allows lawyers to create personalized projects addressing critical legal needs in underserved communities. Participants collaborate with preferred organizations to develop innovative solutions while receiving substantial financial support, health benefits, and professional training. This program not only enhances access to justice but also promotes diversity within public interest careers, empowering candidates to make meaningful impacts in their chosen fields.

The JDF: FIRST LEGO League Explore Grant Program, supported by the John Deere Foundation, aims to enhance participation in STEM for underserved youth. Teams must apply for the grant before registration and ensure compliance with eligibility criteria, including training requirements. This initiative is part of John Deere's commitment to fostering diversity and inclusion in technology and engineering fields, ultimately seeking to impact one million youth by 2030.