Best Large Grants for Nonprofit Organizations in Missouri

The Lasher-Bottorff Award, established by the American Association of Avian Pathologists, recognizes outstanding contributions to poultry health. It honors Dr. Hiram N. Lasher and Dr. C. A. Bottorff, pivotal figures in avian medicine. The award, valued at $1,000, is presented annually to a veterinarian who has made significant advancements in avian diagnostics or technical services over the past decade, promoting the health and productivity of poultry in North America.

The Blake-Nuttall Fund Grants, offered by the Nuttall Ornithological Club Inc, support vital ornithological research, conservation, and education efforts focused on the birds of New England and the Northeast. Eligible organizations must be tax-exempt under section 501(c)(3) of the Internal Revenue Code, while applications from individuals or private foundations are not considered. This initiative aims to foster a deeper understanding and protection of avian species in the region.

The Elliott Coues Award, presented by the American Ornithological Society, honors exceptional contributions to ornithological research without geographic or disciplinary restrictions. This prestigious award includes a medal and an honorarium and is named after Elliott Coues, a pioneering ornithologist. The award emphasizes the importance of diverse nominations and aims to recognize individuals who have made significant impacts in the field of ornithology, thus fostering a vibrant ornithological community.

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Ottawa County Community Foundation Grants

The Ottawa County Community Foundation, Inc. (OCCF) is a public charitable organization created by the citizens of Ottawa County to enrich the quality of life for individuals and families in Ottawa County. Grants from unrestricted funds support a variety of programs in the fields of education, health and social services, economic development, natural resources and the arts.

The Melanoma Research Resident and Fellowship Grant offers $10,000 to support early-career residents and fellows in conducting clinical or laboratory research focused on melanoma. This grant encourages innovative approaches to understanding prevention, detection, and treatment of melanoma, including special emphasis on ocular melanoma. Eligible candidates must have a qualified mentor and conduct research at a U.S. institution. This initiative aims to enhance the landscape of melanoma research and foster the next generation of researchers.

The Kalamazoo Valley Chapter's George L. Disborough TU Research Grant Fund, established in 1990, aims to support graduate-level research on trout habitat and conservation projects aligned with Trout Unlimited's mission. This fund seeks innovative studies on coldwater salmonids and their environments, with a preference for projects conducted in Michigan. It is open to U.S. citizens or permanent residents enrolled in accredited institutions, promoting efforts that enhance the quality of aquatic resources.

Our Mission and Vision

The Wright Foundation for Sustainability and Innovation exists to foster innovative sustainability initiatives that make a positive impact on our planet. We want to find solutions to the complex challenges facing our world today.

Our vision is to facilitate positive action toward sustainable and innovative solutions in agricultural and environmental sectors that reduce carbon footprints and minimize risk for our communities.

Grant Programs

Wright Foundation for Sustainability and Innovation administers projects directly funded by donors that help reduce carbon footprints through carbon positive practices and emission offsetting. The foundation holds open application periods for projects in the contiguous United States, Puerto Rico and Canada that focus on reducing environmental risk through regenerative agricultural practices, habitat restoration and using natural energy sources to make our communities more sustainable.

Reducing Carbon Footprints

The foundation supports projects that work to reduce carbon footprints through the following initiatives.

Habitat Reclamation

• Restoration of habitats creates spaces for native flora and fauna and microorganisms to survive. Natural landscapes are integral to functioning ecosystems and increasing biodiversity, not to mention creating habitats for pollinator species like bees and butterflies that we so desperately need for agricultural success.

Regenerative Agriculture

• Regenerative agricultural practices have a far-reaching impact on the industry and our lives. We aim to reduce carbon emissions by fostering projects that innovate row crop sustainability and dairy, beef, pork and poultry operations to create practices that are sustainable for years to come.

Renewable Energy

• We care about carbon positive practices that harness renewable resources like solar, wind and biomass for improved efficiencies and overall reduction in use. Organic matter often sourced from agricultural production, garbage and tree pruning can be converted to energy in various ways, recycling it back into the agricultural operation that created it or fueling our communities.

Soil

• Soil sequestering practices have wide-reaching benefits like restoring and building organic matter in the soil and increasing biodiversity. It boosts water infiltration and retention and reduces erosion. Through practices like no till, applying organic matter like manure and biochar, and planting cover crops, we improve soil health as well as take CO2 out of the atmosphere.

Tree Planting

• Planting trees is a simple act that makes a huge impact in our urban, suburban and rural communities. They provide shade, release oxygen and improve air quality, improve soil quality and biodiversity, all of which contributes to offsetting carbon emissions.  

• Water
• We want to find ways to protect and restore the integrity of our water resources. We aim to fund projects focused on practices that create efficiencies and reduce the agricultural production impact on water quality and benefit our communities by conserving one of our most important natural resources. 

John Harsch Regenerative Agriculture Grant

Funding for projects adopting best regenerative agricultural management practices that impact one or several of these areas:

• Improve water quality
• Reduce soil erosion
• Increase soil health index
• Reduce synthetic fertilizer use
• Increase effective manure use as a fertilizer
• Increase biodiversity
• Reduce methane and nitrous oxide emissions

The KTGF Fellowship Programs, funded by the Klingenstein Third Generation Foundation, offer $100,000 over two years to support post-doctoral and junior faculty research on ADHD and depression in children, particularly from low-income and under-resourced backgrounds. This initiative aims to foster promising early-career scientists while producing impactful research that benefits affected children and families. Applications are accepted from September 1 to December 15, with specific eligibility criteria outlined for candidates.

The Bonnell Cove Foundation Grant supports non-profit organizations in North America focused on safety at sea and marine environmental initiatives. With a funding limit of $10,000, it prioritizes well-defined projects that can be evaluated for impact. Proposals are accepted biannually, with deadlines on February 1 and September 1 for March and October reviews, respectively. The Foundation seeks innovative solutions for personal safety equipment and environmental stewardship, emphasizing projects that promote sustainable practices in marine operations.

Common Waters: Strengthening Community-based Coastal and Riverine Stewardship

Opportunity Overview

Projects supported by this RFP must be community-based stewardship initiatives (including but not limited to stewardship driven by Indigenous and descendant communities); they should be led by an individual with a strong connection to and/or an existing track record of work in the community(ies) where the project will take place, or by a member of the community themselves, and be designed in response to community needs. Projects can focus on a wide range of specific issues, including (but not limited to) local conservation and ecosystem restoration, climate change adaptation and resilience, or sustainable fishing/agriculture. The RFP will prioritize projects in National Geographic-Lindblad Expeditions destinations, including the Arctic, Asia, Baja California, Costa Rica and Panama, Europe and the Mediterranean, Patagonia, the Peruvian Amazon, the Pacific Northwest, Southeast Alaska and British Columbia, the South Pacific, and the United Kingdom and Ireland. For more detailed information on targeted areas within these regions, please refer to the targeted areas document.

The GSF Foundation Grant supports 501(c)(3) non-profit organizations that enhance the lives of children and families in need. Applications must be submitted by a current GSF Associate who nominates the organization and its project. Since 2002, the foundation has funded over 600 organizations nationwide. It emphasizes personal involvement and contributions from associates, focusing on essential needs such as education tools, food, and shoes for children. Grants are reviewed at local and national meetings.

The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.

The Kansas City Royals Foundation Grants Program has distributed over $25 million since 2001, focusing on Literacy and Education, Healthy and Active Communities, and Military and Veteran Support. Key initiatives include scholarships for underrepresented students, youth engagement through sports, and veteran recognition at games. Organizations within the greater Kansas City area are encouraged to apply, particularly those with budgets under $5 million. The foundation prioritizes projects aligning with its strategic pillars, fostering community growth and support.

The BIE Internship Funding for STEM Students, offered by the Native Forward Scholars Fund, provides financial assistance to Native students for approved internships related to STEM. This initiative helps cover costs such as travel, living expenses, and daily commuting, facilitating valuable professional experiences. By supporting these students, the program aims to enhance Native representation in STEM fields and empower future leaders within their communities, contributing positively to society's growth and diversity.

The Friends of Reservoirs: Mossback Grant offers three grants of $1,000 in Mossback products to eligible members of Friends of Reservoirs organizations. Sponsored by Mossback Fish Habitat, these grants aim to enhance structural habitat in public waters. The total retail value is approximately $1,500. Applicants must cover freight costs, and a $25 application fee applies to each submission. This initiative supports habitat restoration efforts across member organizations.

The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.

The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.

The Arthritis National Research Foundation supports early career researchers in their quest to advance understanding and treatment of arthritis and related autoimmune diseases. Annually, the foundation grants 10 to 20 awards of $125,000 each for two years. Focus areas include osteoarthritis, rheumatoid arthritis, lupus, and more. Eligible investigators must hold an M.D. or Ph.D., be affiliated with a U.S. nonprofit research institution, and commit significant research time. Applications from prior grant recipients or those with certain NIH grants are ineligible.

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5411 - Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty

Grant Information

• Assess current utility practices for incorporating adaptive or flexible decision making into capital improvement planning (CIP) at the portfolio or programmatic level.
• Identify where deep uncertainty most affects CIP decision points, including investment areas prone to lock-in or points of no return.
• Document the institutional processes, frameworks, and governance structures that have enabled utilities to embed adaptive and flexible investment strategies.
• Quantify how adaptive capital strategies compare to traditional CIP approaches in terms of lifecycle costs, rate stability, financial risk exposure, and avoided or deferred capital investments across a range of plausible future conditions.
• Establish practical criteria to help utilities determine which types of capital investments are well suited for adaptive approaches.
• Develop a practitioner-focused playbook that equips utilities to apply adaptive CIP in practice, including case studies, decision trees, trigger points, vulnerability assessment tools, financial and risk insights, and governance guidance.
• Produce tiered recommendations that allow utilities to adopt adaptive CIP practices incrementally.

The Dr. John M. Anderson Excellence in Mental Health Award recognizes outstanding mental health professionals in the St. Louis area who significantly contribute to reducing stigma and promoting mental health in the African American community. This award, presented by the St. Louis County Children’s Service Fund, honors individuals who demonstrate a commitment to improving access to mental health services and advocate for the well-being of children and families. Nominations are evaluated through a rigorous scoring process.

The AISES Indian Motorcycle Academic Scholarship offers $5,000 annually to support Native students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship aims to empower Indigenous students and enhance diversity in STEM. Eligible applicants must be current AISES members, full-time students, and enrolled citizens or descendants of recognized Native tribes. This scholarship not only provides financial assistance but also fosters community and innovation within the STEM landscape.

The ArtsKC Inspiration Grant supports individual artists and small groups in the Kansas City metropolitan area by funding ambitious projects that foster growth and positive community impact. With disciplines ranging from visual arts to theater, these project grants encourage creativity and innovation. In Spring 2024, ArtsKC awarded 12 grants totaling $30,000, with a 14% acceptance rate. Eligible artists must be over 18 and demonstrate professional achievement in their art form.

The AISES Stellantis Scholarship aims to enhance the representation of Indigenous peoples in STEM fields. Funded by Stellantis, this scholarship offers $20,000 for full-time students enrolled in colleges with Mopar Career Automotive Programs. Eligible candidates must be current AISES members and either enrolled citizens or descendants of recognized Indigenous groups. The program not only supports education but also fosters a diverse and inclusive workforce within the automotive industry.

The DFO Research, Education, and Conservation Grant supports projects focused on birds and their habitats, prioritizing initiatives in the Denver area and Colorado's Front Range. Established in 1994, the fund encourages research, education, and conservation efforts with grants typically under $2,000. Recent funded projects include studies on owl habitats and educational programs for young birders. The fund aims to advance knowledge and appreciation of avian species through targeted financial support.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5426 - Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies

Grant Information

Evaluate the impact of non-point or dispersed sources of per- and polyfluoroalkyl substances (PFAS) in the sewershed (including PFAS-contaminated groundwater infiltration) on PFAS mass loading to wastewater treatment plants.

Assess how PFAS loading from non-point or dispersed sources of PFAS in the sewershed may affect treatment efficiency and reuse water quality.

Improve understanding of PFAS precursor contributions.

Identify potential strategies to mitigate PFAS loading from non-point or disbursed sources of PFAS in the sewershed.

The Kalamazoo Valley Chapter's Stanley Weber Projects Fund honors a dedicated member by supporting projects that enhance coldwater fisheries and their habitats. Offering grants up to $5,000 annually, the fund prioritizes non-profit initiatives that foster conservation, restoration, and public education while promoting volunteer engagement. Recognition through plaques or media announcements is requested for grant recipients, ensuring the legacy of Stanley Weber continues to impact the community positively.