Best Operating Grants for Nonprofits in Ohio

Ohio Department of Health

The Ohio Department of Health’s mission is advancing the health and well-being of all Ohioans by transforming the state’s public health system through unique partnerships and funding streams; addressing the community conditions and inequities that lead to disparities in health outcomes; and implementing data-driven, evidence-based solutions.

Rural Health Transformation Pharmacy Initiative

Summary

The Rural Health Transformation Program (RHTP) was authorized by the One Big Beautiful Bill Act (Section 71403 of Public Law 119-21) and empowers the state to strengthen rural communities by improving healthcare access, quality and outcomes by transforming the current system. Five key strategic goals of the program, as defined by the Centers for Medicare and Medicaid (CMS) are:

• Make rural America healthy again
• Sustainable access
• Workforce development
• Innovative Care
• Technology Innovation

Ohio’s plan aligns with federal priorities to improve the health of rural residents through sustainable access, workforce development, innovative care, and tech advancement. As part of Ohio's Rural Health Transformation Program, the selected vendor will engage in activities to maximize the role that pharmacists and pharmacies play in ensuring access to healthcare in rural Ohio and Support systems and policy changes to allow pharmacists and pharmacies in rural Ohio to operate under an expanded scope of practice and provide training these professionals need to do so successfully. This work with pharmacists supports the RHTP objective of improving the health of rural Ohioans through chronic disease management, care coordination, and reducing drug related adverse events

The Kosciuszko Foundation offers Tuition Scholarships for American students of Polish descent pursuing graduate studies in the U.S. Scholarships can provide up to $12,000 for full-time studies, including master's and Ph.D. programs. Eligible applicants must be U.S. citizens or legal residents with Polish heritage and maintain a minimum GPA of 3.0. This program aims to foster educational exchanges and cultural understanding between the U.S. and Poland, supporting various fields of study.

The Looking Out Foundation Grant supports social justice and humanitarian initiatives, having donated nearly $6 million to various causes globally. With an average donation of $25 per campaign, it aids organizations focused on disaster relief, racial justice, and support for marginalized communities. Eligible applicants must be tax-exempt public charities under Section 501(c)(3). The foundation prioritizes diverse funding sources and encourages organizations to adapt to changing needs, with grant allocations ranging from $5,000 to $25,000.

The Transportation Alternatives Program (TAP) by the Ohio Department of Transportation funds projects enhancing non-motorized travel, historic preservation, and environmental efforts. It supports local governments in implementing initiatives that improve accessibility and safety for pedestrians and cyclists. Eligible projects include shared paths, bike lanes, and upgrades for ADA compliance. The program prioritizes connections to activity centers, ensuring public accessibility and engagement in transportation planning.

The Ohio Developmental Disabilities Council aims to enhance transportation opportunities for individuals with developmental disabilities through funded projects. By expanding access to transportation, the council seeks to empower individuals with I/IDD to achieve independence and improve their quality of life. Two projects may receive $50,000 annually for five years, supporting diverse entities in Ohio. This initiative aligns with the council's mission to foster inclusion and community involvement for people with disabilities.

Ecolab Foundation

Ecolab Foundation is a philanthropic arm of Ecolab dedicated to advancing community well-being through programs that promote education, environmental stewardship, and public health. Its mission is to create positive social impact by supporting initiatives that strengthen communities and foster sustainable development.

The foundation’s primary areas of engagement include educational programs that enhance learning and workforce readiness, environmental projects that encourage conservation and sustainability, and health-related initiatives that improve hygiene and safety. It focuses on partnerships that deliver measurable benefits and long-term impact.

Ecolab Foundation operates primarily within the United States while also supporting global initiatives aligned with its corporate responsibility goals. Its geographic scope reflects a commitment to addressing local community needs and contributing to broader sustainability efforts.

The foundation collaborates with nonprofit organizations, educational institutions, and community-based groups. It prioritizes partnerships that demonstrate strong governance, clear objectives, and alignment with its mission of education, health, and environmental responsibility.

Ecolab Match Program

Ecolab established the Volunteer and Community Relations programs to encourage and reward Ecolab employee and alumni involvement in the communities where people live and work. There are three programs including the Board Leadership Volunteer Grant.

Board Leadership Volunteer Grant

Ecolab will donate up to $500 USD annually to a qualifying 501(c)3 organization (some restrictions apply) for which an eligible person serves on the Board of Directors. 

Focus Areas of Giving

• Youth and Education: programs that promote youth development, particularly for programs that ensure all students are successful
• Civic & Community Development: affordable housing, work readiness, crisis assistance and hunger relief
• Environment & Conservation: hands-on environmental learning programs, environment and conservation organizations
• Arts & Culture: arts education for children and youth as well as support for museums and the performing arts

The OneOhio Recovery Foundation is dedicated to addressing the opioid epidemic by allocating funds from pharmaceutical settlements to enhance substance misuse prevention, treatment, and recovery initiatives across Ohio. For Regional Grant Cycle #2, the Board authorized $40 million to support evidence-based investments in local communities. This funding model aims to create sustainable impacts while ensuring fiscal responsibility and transparency in managing resources for long-term recovery efforts.

The George Gund Foundation provides grants to support various program areas including climate and environmental justice, creative culture and arts, public education, thriving families and social justice, and vibrant neighborhoods and inclusive economy in Cleveland. The foundation prioritizes projects that advocate for underrepresented communities and work towards sustainability and equity. By fostering collaboration and policy change, it aims to enhance the quality of life for all residents while addressing systemic barriers to opportunity.

The Programmatic Support - Education Pillar Award by Honda aims to enhance workforce readiness in the manufacturing sector. It supports nonprofit organizations and schools focused on hands-on programs in design, software/data analytics, and AI/machine learning. Eligible applicants must be US-based and have 501(c)(3) status. The initiative prioritizes projects that train individuals for manufacturing roles, develop technical skills, and introduce automation to prepare for evolving industry demands, ultimately fostering economic prosperity in local communities.

The Sachs Family Foundation Grant aims to enhance the quality of life for economically and educationally disadvantaged individuals and families. The Foundation supports self-sustaining charitable organizations focusing on economic and educational opportunities, particularly in low-income communities in the U.S. and developing countries. Grants are available for various initiatives, including education, housing, and job training, with a keen interest in programs that demonstrate clear potential for sustainability.

The Columbus Foundation

In 1943, during the darkness of World War II, a group of passionate citizens, led by Columbus businessman Harrison M. Sayre, envisioned a way to improve the well-being of the community and the quality of life in central Ohio. With little more than this sound idea and faith, The Columbus Foundation was established.

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

Opportunity Youth Grants

Funds recreational programs benefiting youth and ensure that all young people enter adulthood prepared to pursue opportunities to live well.

In 2015, The Columbus Foundation commissioned a research report from Jobs for the Future to better understand the challenges youth and young adults in Franklin County ages 18 to 24 were facing. At that time, it was found that 20,500 young people, referred to as opportunity youth, were not on track to graduate and/or were disconnected from society. This presented an opportunity for our community to reach out to them, intensify our efforts to reconnect, and facilitate pathways to success and self-sufficiency.

A cross-sector group of community stakeholders, including The Columbus Foundation, worked in collaboration to arrive at the theory of change that all youth should be able to enter adulthood prepared to pursue opportunities to live well. Six focus areas were identified: Civic Engagement, Education, Health and Wellness, Housing, Support Systems, and Workforce.

This Opportunity Youth coalition continues to work together to create a continuum of support that both engages youth who are currently disconnected while working upstream to ensure all youth enter adulthood prepared to pursue opportunities to live well.

About Us

The mission of the Ohio Developmental Disabilities Council (Ohio DD Council) is to create change that improves independence, productivity and inclusion for people with developmental disabilities and their families in community life. The Ohio DD Council operates under the authority of the federal Developmental Disabilities Assistance and Bill of Rights Act of 2000 (DD Act) and is a part of the Ohio DD Network. The Ohio Department of Developmental Disabilities assists and supports the Ohio DD Council as the federally mandated designated state agency.

All In Play: Empowering Inclusive Sports in K-12 Schools

This grant will support the development and expansion of inclusive K–12 athletic programs that increase access to meaningful participation for students with intellectual and developmental disabilities (I/DD), including those with significant support needs. The goal is to build school and community capacity, not to deliver direct services.

Grantees will implement a train‑the‑trainer model that equips school staff, coaches, and university partners with practical strategies for inclusive sports program design, adaptive coaching, and peer‑to‑peer engagement. Projects must include approaches that prepare trainers to support students across the full spectrum of abilities and to train student peers in disability awareness, communication, and inclusive teamwork.

Funded activities may include developing training materials, delivering trainer sessions, providing technical assistance to schools, building partnerships with university PT/OT programs, and collecting best practices. Projects should emphasize sustainability, replication, and long‑term systems change.

Applicants should demonstrate the ability to:

• Build capacity within schools to design and sustain inclusive athletic programs.
• Train educators, coaches, and university partners to support students with all levels of disability.
• Incorporate structured peer‑engagement models (e.g., buddy systems, mentorship).
• Provide technical assistance that helps schools implement inclusive practices effectively.
• Evaluate training effectiveness and share outcomes.

This grant aligns with ODDC priorities by promoting community inclusion, strengthening local capacity, supporting cross‑disability participation, and fostering collaborative partnerships that lead to lasting systemic change.

The Japan – U.S. Global Partnership Grant Program aims to foster collaborative projects addressing global issues through partnerships between Japanese and American organizations. It focuses on policy-oriented research and dialogue among diverse professionals, including academia and grassroots practitioners. Key thematic areas include resilience, inclusivity, and advancements in science and technology. Projects outside these themes may also be eligible if aligned with grant goals, covering topics like climate change, public health, and digital transformation.

The Doree Taylor Charitable Foundation supports charitable organizations focused on basic provisions for underserved populations, humane care of animals, health care services, public media, and environmental initiatives. The foundation prioritizes organizations in Boothbay Harbor, Southport, and Brunswick, and encourages requests for general operating support, program support, and capital projects, while maintaining a focus on the impact of their services.

Request for Proposals: Launchpad Funds

Background

Coefficient Giving is increasing its giving, primarily to prepare for the billions of dollars in new philanthropic capital that may become available in the coming years. Our increased giving in global health and wellbeing is a temporary surge, with two objectives: to smooth funding and pull forward initiatives we expect to be cost-effective, and to help create an ecosystem of regrantors and implementers with the capacity to allocate this new money as cost-effectively as possible. Additional context on our scaling is provided in this blog post. 

With new potential capital on the way, we want to increase the supply of actionable and fundable plans to address some of the world’s hardest problems. We’re looking for specific, credible strategies to convert funding into measurable progress. Our ideal funds are:

However, we are also open to funds that are thematic and don’t have a quantified goal — for example, a fund organized around a promising type of intervention. Such funds still need to be led by a single, identifiable person who is accountable for the fund’s direction.

Through this request for EOIs, we aim to seed or scale Launchpad Funds that can grow to $100m+ over the next few years. We don’t seek scale for its own sake; it is a proxy for the ambition of the fund, and a signal that the problem is large and tractable enough to justify deploying significantly more capital over time.

What we will fund

• We expect to support established ideas that have either not yet secured anchor support or could significantly scale beyond their existing level of funding.
• This funding can cover operating expenses, but we expect most of it to be used for activities that make progress on the fund’s goals — whether through regranting or direct implementation.
• For exceptional proposals, we may consider funding levels beyond $50m. We anticipate higher funding levels will involve more thought partnership from our team.
• While we don’t expect to make grants longer than 36 months, funded proposals may later be considered for additional funding beyond the initial period.

The Global Health and Wellbeing Grantmaking program by Coefficient Giving focuses on addressing critical health and welfare issues worldwide. With an emphasis on proactive engagement and evidence-based solutions, the initiative supports projects that improve health outcomes and wellbeing. The program prioritizes funding for organizations tackling neglected global health challenges, advocating for effective philanthropy, and enhancing the lives of both humans and animals in vulnerable communities.

The Max and Victoria Dreyfus Foundation offers grants to support diverse initiatives, including museums, educational programs, and environmental activities. Aiming to make a significant impact with modest funding, the Foundation targets IRS-qualified non-profits in the U.S. Grants typically range from $1,000 to $20,000, fostering community development and enhancement. Organizations focused on youth, seniors, and individuals with disabilities are particularly encouraged to apply, as the Foundation seeks to empower those in need.

Ohio Department of Health

The Ohio Department of Health’s mission is advancing the health and well-being of all Ohioans by transforming the state’s public health system through unique partnerships and funding streams; addressing the community conditions and inequities that lead to disparities in health outcomes; and implementing data-driven, evidence-based solutions.

Breast and Cervical Cancer Project

The Ohio Department of Health (ODH), Medical Director, Bureau of Health Improvement and Wellness announces the availability of grant funds.

No grant award will be issued for less than $30,000. The minimum amount is exclusive of any required matching amounts and represents only ODH funds granted. Applications submitted for less than the minimum amount will not be considered for review.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research.

MNRS Distinguished Service Award

The Distinguished Service Award recognizes an MNRS member who has demonstrated sustained influential leadership and service to the organization, such as chairing committees, organizing annual conference activities, or serving on the Board of Directors. 

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research. 

Harriet H. Werley New Investigator Award

The purpose of the Harriet H. Werley New Investigator Award is to recognize the scientific contribution of a new investigator who has conducted nursing research that has the potential to enhance the science and practice of nursing.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research. 

Distinguished Contribution Award

The purpose of the Distinguished Contribution Award is to recognize the scientific contribution of a member who has conducted or promoted research, which has enhanced the science and practice of nursing in the MNRS region.

Women's Hub and Spoke Grant

DBH is seeking information in providing funding opportunities to non-profit organizations serving pregnant and postpartum women, interested in providing more information to DBH regarding the Women’s Hub and Spoke Grant, to access funding to strengthen and expand integrated, evidence-based substance use disorder (SUD) and maternal behavioral health services. The program seeks to improve maternal and infant health outcomes by addressing SUD and co-occurring substance use and mental health conditions through comprehensive screening, treatment, recovery supports, and workforce development. This opportunity may provide up to $500,000 for facilities that are already appropriately licensed and certified by the DBH in Ohio communities. Funds must be used for any expenses in developing a hub-and-spoke maternal care model in areas with little maternal healthcare integration. Expenses may include, hiring appropriately credentialed staff to fulfill hub and spoke requirements, early identification of women through evidence-based screening tools, timely enrollment, care coordination, and MAT/MOUD workforce expansion to train and mentor healthcare professionals with prescribing authority for buprenorphine and naltrexone products. All grant recipients are expected to participate in a Six Sigma systems improvement process that will bring alignment among stakeholders around creating a safer, more coordinated, and more compassionate care journey for perinatal women.

The Resilient and Connected Appalachians Grant Program, offered by The Nature Conservancy, provides up to $100,000 for projects that acquire land and easements throughout the Appalachian region. This program emphasizes equitable conservation, aiming to support historically marginalized communities and enhance access to nature while addressing climate change impacts. Projects must demonstrate community engagement and align with the program's goals to protect vital habitats and foster resilience in the face of environmental challenges.

The AES Ohio Foundation's Power Grants aim to create lasting community impact through innovative programs across its 24-county service area. With $822,000 allocated for 2024, these grants support initiatives addressing basic needs like food and housing, enhancing education, and fostering diversity and inclusion. The Foundation commits to at least two grants annually, prioritizing projects that demonstrate measurable outcomes. This approach aligns with their goal to uplift local communities and empower individuals to improve their lives.

The Council Connect grant from the Ohio Developmental Disabilities Council aims to enhance public awareness of developmental disabilities. It will create resources and outreach initiatives to educate communities, especially underserved populations. The selected grantee will coordinate communication efforts to share stories, promote resources, and engage with community organizations. This initiative aligns with the Council's mission to improve independence and inclusion for individuals with developmental disabilities, ultimately fostering a more informed and connected community.

The Fred and Barbara Erb Family Foundation is dedicated to fostering a healthy Great Lakes ecosystem and a vibrant Southeast Michigan community. Since its inception, it has invested over $180 million in environmental, cultural, and educational initiatives. As it transitions to spend down its assets by 2034, the Foundation aims to make bold, impactful investments that address urgent community needs and promote sustainable development.

What does this program do?

It provides loans and grants to Microenterprise Development Organizations (MDOs) to:

• To help microenterprises startup and growth through a Rural Microloan Revolving Fund.
• Provide training and technical assistance to microloan borrowers and micro entrepreneurs.

Microenterprise Development Organizations must demonstrate experience in managing a Revolving Loan Fund, or:

• Certify that it or its employees have received education and training from a qualified microenterprise development training entity so that the applicant has the capacity to manage such a revolving loan fund.
• Demonstrate that it is actively and successfully participating as an intermediary lender in good standing under the U.S. Small Business Administration (SBA) Microloan Program or other similar loan programs as determined by the Administrator.

 What kind of funding is available?

• Grants are available to provide technical assistance to rural micro-entrepreneurs or microenterprises, up to $205,000 annually.
  • Funding at the requested level is not guaranteed, and at least 15 percent matching funds are required.
• Loans of $50,000 to $500,000 may be used for establishing a Rural Microloan Revolving Fund managed by the Microenterprise Development Organization.
  • Total aggregate debt is capped at $2.5 million.

What are the loan terms?

• Maximum term is 20 years.
• Two-year payment deferral.
• Must establish a loan loss reserve fund.

What terms are required on loans to ultimate recipients?

• Up to $50,000.
• Fixed interest rate.
• Limited to 75 percent of project cost.

How may the funds be used?

Microlenders may make microloans for qualified business activities and expenses including, but not limited to:

• Working capital.
• Debt refinancing.
• Purchasing equipment and supplies.
• Improving real estate.