Best Operating Grants for Nonprofits in Ohio

The Cavaliers Community Foundation (CCF) is a charitable organization established in 1993 that supports local non-profits focused on youth development in Northeast Ohio. With over $25 million granted, CCF prioritizes programs that enhance education, health, and wellness for at-risk youth. Eligible organizations must be 501(c)(3) charities with a minimum of three years of operation. Grants typically average $10,000, aiming to foster community impact and support for young people.

The Therapeutic Giving: Oncology program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatments and services, promote health equity, and strengthen healthcare workforces. It supports programs that raise disease awareness, empower patients, and improve health systems with measurable outcomes. Eligible applicants include nonprofit organizations with 501(c)(3) status, emphasizing innovative programs addressing healthcare disparities and unmet needs.

The Therapeutic Giving program from Johnson & Johnson Innovative Medicine aims to support local and regional organizations focused on improving patient access to treatment and advancing health equity. Eligible applicants include 501(c)(3) nonprofit organizations, with funding preferences for programs that address significant healthcare disparities, mental health initiatives, and innovative solutions with measurable outcomes. The application period for local organizations runs from March 1 to May 31, while national organizations can apply in September.

The Therapeutic Giving initiative by Johnson & Johnson focuses on funding programs in neuroscience aimed at enhancing patient access to treatments and promoting health equity. Nonprofit organizations classified as 501(c)(3) can apply for support from March 1 to May 31. The initiative emphasizes innovative, measurable programs in areas like Alzheimer’s disease and mental health, prioritizing those that address healthcare disparities and improve quality of life for affected individuals.

The U.S. Healthcare Donations program by Amgen aims to support not-for-profit organizations in the healthcare sector. As a leading biotechnology company, Amgen provides funding for initiatives that improve science, technology, education, and public awareness on medical conditions. Organizations eligible for funding must be tax-exempt entities, focusing on genuine philanthropic efforts that align with Amgen's mission to enhance health outcomes and reduce the burden of diseases.

The IC25 Injury Prevention-Child Injury Prevention Solicitation by the Ohio Department of Health aims to fund programs that reduce child injuries and fatalities in Ohio. Through evidence-based strategies, this grant addresses issues like traumatic brain injuries, youth violence, and transportation safety. With a total funding of $220,000 over four years, eligible agencies can apply for up to $110,000, ensuring comprehensive support for local initiatives focused on enhancing child safety.

The Entergy Charitable Foundation Grant focuses on supporting initiatives that foster thriving communities through education, poverty solutions, and environmental programs. The foundation prioritizes funding for 501(c)(3) organizations and similar entities. Key areas include education development, innovative poverty solutions, and environmental restoration efforts, such as coastal wetland preservation. Organizations are encouraged to apply at least three months before funding is needed, ensuring timely support for impactful community projects.

The Akron Community Foundation's Health & Human Services Grant focuses on enhancing the quality of life in Summit County. It supports approved 501(c)(3) organizations addressing essential needs such as food, shelter, and medical care. Grants prioritize systemic impact, organizational strength, and inclusiveness, aiming for sustainable solutions that benefit the community. The foundation seeks to empower nonprofits and ensure ethical stewardship of donor investments, ultimately contributing to self-sufficiency and wellness for the county's most vulnerable residents.

The Thomas H. White Foundation offers grants to tax-exempt, non-profit organizations in Cuyahoga County, Ohio, focusing on programs that enhance early childhood education, promote educational success for K-12 students, and support workforce readiness. Eligible organizations must primarily serve residents of Cleveland and comply with specific requirements. Notably, capital campaign requests are ineligible. For more details, applicants are encouraged to contact the foundation directly.

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Ottawa County Community Foundation Grants

The Ottawa County Community Foundation, Inc. (OCCF) is a public charitable organization created by the citizens of Ottawa County to enrich the quality of life for individuals and families in Ottawa County. Grants from unrestricted funds support a variety of programs in the fields of education, health and social services, economic development, natural resources and the arts.

The Columbus Realtors Foundation supports real estate-related initiatives in central Ohio through its community grants. With over $600,000 invested since 2008, the foundation aids organizations that address homelessness, repair homes for low-income families, and promote affordable housing. Established in 1991, it aims to enhance the real estate environment while empowering local nonprofits and government entities to foster healthy communities.

The Ron Goellner Conservation Fund Award, administered by the Cryptobranchid Interest Group, offers grants up to $2,000 for projects focused on the conservation of giant salamanders. This initiative supports innovative research, field conservation, and educational initiatives that aim to protect these species and their habitats. Open to all applicants, the fund prioritizes projects that demonstrate broad conservation impact and partnerships. Applications are automatically considered for two separate grants of up to $1,000 each.

The Ohio Environmental Protection Agency's Targeted Brownfield Assessment (TBA) Program offers essential property assessment services at no cost to local government entities. This program is designed to minimize contamination uncertainties for brownfield sites, facilitating cleanup and redevelopment efforts. Eligible applicants include counties, cities, and non-profit organizations. TBA services, such as Phase I Environmental Site Assessments and remedial action plans, support real estate transactions and funding applications, ultimately transforming blighted properties into valuable community assets.

The Surface Transportation Block Grant (STBG) program, managed by the Ohio-Kentucky-Indiana Regional Council of Governments (OKI), allocates federal funds for transportation projects aimed at enhancing regional planning. This funding, capped at $6 million for Ohio and $5 million for Kentucky, supports roadway improvements and various transportation initiatives within the OKI urban area, promoting efficient project implementation and sustainable development.

The Thornton S. Glide, Jr. and Katrina D. Glide Foundation provides grants to qualified 501(c)(3) organizations in California that focus on animal protection, land conservancy, agriculture, and civic endeavors. Established in 1995, the foundation prioritizes grants for specific capital acquisitions and does not support operational costs or direct aid to individuals. Emphasizing local impact, California-based organizations are favored over out-of-state counterparts.

The Maine Cancer Foundation is seeking proposals for cancer screening initiatives aimed at early detection and prevention. This RFP focuses on screenings for breast, cervical, colorectal, lung, prostate, and skin cancers. Proposals should align with evidence-based practices endorsed by the CDC and U.S. Preventive Services Task Force. Interested applicants are encouraged to consult with MCF prior to submission to discuss project concepts and receive feedback on draft applications.

TC Energy’s Build Strong program supports vital organizations in communities near its operations. By providing grants, scholarships, and in-kind support, the program aims to enhance safety, education, environmental protection, and community well-being. Eligible applicants include non-profits and community groups addressing local needs. Ineligible activities include operational expenses and for-profit endeavors. The program prioritizes projects demonstrating measurable community impact, fostering a collaborative relationship between TC Energy and local stakeholders.

Ohio Department of Health

The Ohio Department of Health’s mission is advancing the health and well-being of all Ohioans by transforming the state’s public health system through unique partnerships and funding streams; addressing the community conditions and inequities that lead to disparities in health outcomes; and implementing data-driven, evidence-based solutions.

The Breast and Cervical Cancer Project- Community Health Worker (HW27)

The Ohio Department of Health (ODH), Bureau of Health Improvement and Wellness announces the availability of grant funds.

The H2Ohio Rivers Initiative: Chloride Reduction Grants support Ohio municipalities, townships, villages, and counties in adopting best management practices to reduce chloride from deicers impacting water resources. Grants, up to $75,000, aim to improve storage and application of road salt to protect aquatic ecosystems. The program addresses the growing concern of chloride pollution in Ohio's waterways by funding necessary equipment and facilities, promoting collaboration among local governments to maximize impact.

The AdvoCare Foundation, established in 1993, aims to promote health and wellness for children through its grant program. Focused on year-round initiatives, the foundation supports local communities where AdvoCare distributors operate. Grants typically last one year with an average funding of $25,000, although multi-year support may be available. The foundation prioritizes programs that foster positive health changes and encourages collaborative efforts with previous grantees.

The Research and Development Grant Program by the Ohio Water Development Authority (OWDA) supports innovative projects in wastewater, water management, solid waste, and energy resource development. Eligible applicants include local government agencies and higher education institutions. Priority is given to proposals that enhance water quality, technology, equity, and resilience. Grants are contingent upon available funding, and applicants are advised to review the Participation Agreement before applying.

The WKKF Grant, offered by the W.K. Kellogg Foundation, is dedicated to fostering a future where every child and family thrives. With a focus on nurturing early education, accessible healthcare, and equitable food systems, this grant supports initiatives that empower communities across the U.S. and parts of Mexico and Haiti. Organizations meeting IRS regulations and being legal entities, particularly 501(c)(3) nonprofits, are encouraged to apply for funding to create lasting impacts in their communities.

The NACD Technical Assistance Grants program, in partnership with NRCS, has been enhancing conservation district support since 2018. By funding staff hires, it aims to improve service for agricultural producers and address conservation workload challenges. The initiative focuses on outreach, education, and civic engagement to empower local communities, promote sustainability, and support historically underserved producers in implementing conservation practices, thereby fostering both individual and community resilience.

The Delaware County Foundation's Community Grants program aims to strengthen communities through charitable giving. Since its inception in 1995, the foundation has provided over $18 million in funding to support various nonprofit organizations in Delaware County, focusing on areas such as animal welfare, arts and culture, basic needs, education, economic opportunity, and environmental sustainability. Organizations addressing these critical areas are encouraged to apply for funding to enhance community well-being.

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

Ohio Department of Health

The Ohio Department of Health’s mission is advancing the health and well-being of all Ohioans by transforming the state’s public health system through unique partnerships and funding streams; addressing the community conditions and inequities that lead to disparities in health outcomes; and implementing data-driven, evidence-based solutions.

Ohio Rural Health Workforce Pipeline; Pathways, Upskilling, and Retention

Summary

Ohio recognizes the need to develop long-lasting pipelines that engage students at the earliest stages of career planning to educate them about the numerous opportunities that exist in healthcare. This is vitally important in rural areas where the need for workforce is great and we have the opportunity to create pathways for Ohio’s students in K-12 education settings to explore rural health careers, initiate learning in high school, continue training close to home (in technical/trade schools, community colleges, or universities with significant rural engagement), and secure careers in health provider settings within the rural communities that are most familiar to them. Our activities in this initiative will place high priority on integrating pipelines, recruitment and retention activities for 5-year work commitments, and upskilling and workforce development in RHTP sites. Projects will be implemented in partnership with academic institutions, other training facilities, and professional and paraprofessional associations to:

• In conjunction with the ODH and other state agencies, identify and prioritize rural healthcare workforce needs in Ohio’s 73 identified rural counties.
• Coordinate workforce pipeline activities between high schools, universities, community colleges, career technical schools, and healthcare employers. Activities include career awareness/exploration, pathways education awareness, and career awareness programs in K-12 education, secondary education programs, rural work-based learning/apprenticeships, career placement agreements with employers, and coordinating all Federal and State workforce development and financial resources. This could also include a multi-state approach for educational and healthcare systems that transcend state lines. A focus is placed on placements in RHTP facilities and partner programs funded through Ohio’s RHTP
• Provide rural recruitment and retention incentives and 6-month housing stipends for those who relocate to serve in rural communities for a minimum of 5-year commitments. This project will support filling workforce needs for various healthcare capacities, e.g., MD/DO, nurses, pharmacists, therapy providers, dietitians, behavioral health, oral health, optometry, audiology, Community Healthcare Workers (CHW)/navigators, etc. This could also include a multi-state approach for educational and healthcare systems that transcend state lines.
• Identify and promote continuing education opportunities for Ohio’s healthcare workforce.
• Collaborate with ODH, other state agencies, and vendors who are operationalizing RHT initiatives to support the workforce needs of those projects.

The Levin Family Foundation Grant supports nonprofits focused on critical issues in Montgomery County, Ohio, such as the opiate epidemic, human trafficking, anti-bullying, and suicide prevention. Established in 1996, the foundation has invested over $12 million globally, emphasizing projects that align with its mission. Eligible organizations must be IRS 501(c)(3) tax-exempt. Priority is given to initiatives in the Greater Dayton Area, fostering positive community impact.