Best Small Grants for Nonprofits in Ohio

Greater Toledo Community Foundation

Greater Toledo Community Foundation transforms generosity into lasting impact. With over $510 million in assets across 1,000+ funds, we've granted more than $370 million to strengthen education, health, arts, and social services throughout our region.

We connect donors with causes they care about while bringing together leaders, organizations, and resources to tackle our community's biggest challenges. What began with Walter E. Terhune's vision in the 1920s continues today as we help individuals, families, and businesses create positive change that will benefit our region for generations.

Healthy Aging Fund

The Community Foundation is funding programs that help older adults (60+) stay healthy, connected and independent.

This initiative follows the Ohio Department of Aging's State Plan, shaped with input from the Area Office on Aging of Northwestern Ohio. Priorities of the plan include cognitive health, chronic disease reduction, mental health, social inclusion, and nutrition access, plus engagement opportunities, physical activity, and preventive screenings. The plan is built on research and input from content-area experts.

The Foundation’s Focus

The Healthy Aging Fund is seeking proposals aligned with the State Plan and the Community Foundation's place-based priorities: programs that promote physical and mental health, reduce social isolation and strengthen community connections for older adults.

The Community Foundation seeks to identify collaborative approaches that work well enough to scale. This is a chance for northwest Ohio providers to test new approaches and collaborations: the kind with real potential to increase impact for participants and move the needle on broader community goals.

Funding Priorities

• Multiple partners with complementary expertise, prioritizing diversity of resources across agencies
• Programs delivered through or including senior centers, community centers or long-term care facilities
• Diverse programming that reaches more participants
• Accommodations for specific needs — memory care, vision loss, etc.
• An educational component

The Community Foundation is seeking cross-agency partnerships that expand access to diverse programming and have real potential to scale. Available for projects up to two years. See more in the Grant Guidelines. 

Funding Innovative Research

Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.

Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments. 

When possible, CKc will prioritize funding research:

• with a focus on cancers that are under-funded or under-researched,
• with a focus on patient populations who are traditionally underserved.

When possible, CKc will prioritize funding researchers of diverse backgrounds.

For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).

Research Grants

Grant Program: Clinical Trial

$200,000 over 3 years

• PI must hold an academic appointment at the Assistant Professor level or higher
• Preclinical studies must be complete
• If an FDA Investigational New Drug (IND) application is necessary for the proposed clinical study, the IND application should already have passed FDA initial review and be active
• If the PI has recruited additional patient enrollment sites, local IRB approval must be obtained for each site.

• How many treatment options would this study provide for children?
• How accessible is this study for children and families to access?

Quest Diagnostics Foundation

Established as a 501(c)(3) nonprofit organization, the Quest Diagnostics Foundation is committed to addressing the systemic root causes of health disparities. By combining corporate resources with trusted community leadership, we fund and scale evidence-based initiatives that promote wellness, prevent chronic disease, and empower individuals.

We focus our resources on three critical, interconnected clinical and social interventions to build sustainable health improvement:

• Strengthening the community health workforce
• Addressing social drivers of health (SDoH)
• Promoting the prevention, early detection, monitoring, and treatment of disease through diagnostic testing

About Quest for Healthy Communities Champions

The Quest for Healthy Communities Champion award was created to honor, uplift, and support outstanding organizations across the United States that are actively living our core purpose:

Working together to create a healthier world, one life at a time.

Whether you are expanding access to life-saving screenings, supporting maternal and family wellness, or addressing critical social drivers of health, your dedication is moving us closer to an equitable healthcare future. We want to recognize and celebrate your impact.

What we celebrate: Our core impact pillars

The Champions we look to honor are community-first organizations and coalitions tackling critical disparities head-on. We are especially excited to spotlight work that advances health, addresses social drivers of health, fosters community-clinical linkages and develops the community workforce. Examples of this work could include: 

• Programs actively dismantling clinical barriers to ensure every individual—regardless of zip code, background, or income—has access to high-quality care
• Innovators providing creative solutions for food security, transportation, health education, and maternal-child support networks
• Organizations bringing critical care directly to those in need through mobile clinics, community health workers, and localized diagnostic screenings
• Organizations finding creative ways to engage the communities they serve directly into the solutions they are delivering

The award: Selected organization champions will receive a $10,000 grant.

The FY25-FY26 Advanced Transportation Technology and Innovation (ATTAIN) grant program aims to enhance transportation through the deployment of innovative technologies. It focuses on improving safety, mobility, and efficiency while fostering economic competitiveness. Projects funded will prioritize core infrastructure improvements and address roadway congestion, aligning with the Trump Administration's goals. The program emphasizes economic opportunities and community benefits, ensuring that selected projects contribute positively to families and communities, ultimately enhancing their quality of life.

The Philadelphia Chromosome Negative Myeloproliferative Neoplasms (MPN) Grant, offered by the Patient Advocate Foundation, provides crucial financial assistance to patients facing this cancer type. It covers out-of-pocket healthcare costs, including medication copays and insurance premiums, ensuring those affected can access necessary treatments. With a focus on personalized case management, the foundation has supported millions in navigating their healthcare needs, emphasizing the importance of timely and affordable care for patients diagnosed with MPN.

The Quadratec Cares 'Energize The Environment' Grant Program is dedicated to supporting individuals and organizations in the U.S. focused on environmental improvement. With two grants of $3,500 awarded annually, the program encourages initiatives like trail restoration and community educational projects. This grant aims to empower passionate individuals to enhance environmental awareness and stewardship, ensuring a healthier planet for future generations.

The Oriental Trading Company Corporate Giving Program focuses on enhancing the lives of children through education, youth programming, healthcare, and human services. With a commitment to making the world a better place, they support organizations that are tax-exempt under Section 501(c)(3) or public educational institutions. Their initiatives aim to foster community partnerships and provide essential resources to youth in need, ensuring they have access to vital services and opportunities for growth.

The Smart Growth America Community Connectors Grant Program supports small and mid-sized cities in addressing divisive infrastructure caused by dangerous roads. With funding from the Robert Wood Johnson Foundation, this program aims to reconnect communities through temporary street safety projects while fostering skills and partnerships. Eligible teams must represent populations of 50,000 to 500,000 and include both government and community-based organizations. Priority will be given to projects benefiting low-income communities historically affected by disinvestment.

The Saint Luke's Foundation Community Grant aims to enhance local health by providing financial support to residents in Buckeye – Shaker, Mt. Pleasant, and Woodland Hills. Grants of up to $6,000 are available for health-improving projects led by community members, such as community gardens and mentoring programs. The Resident Advancement Committee awards these grants from March to September annually, empowering local leaders to address health equity and foster positive change within their neighborhoods.

Harry C. Anthony, Jr. Scholarship

Essay:

• Describe yourself and explain why you are interested in a career in medicine.

Awards:

• One-time award of $2,500

The Park Foundation Grants: Media support public interest media that raises awareness of critical environmental and social issues. They prioritize funding for investigative journalism, media policy, public broadcasting, and documentary films to promote a better-informed citizenry. Eligible organizations must be 501(c)(3) certified, and funding is aimed at projects that ensure diverse perspectives and community engagement. The foundation is committed to fostering a robust democracy and independent media, reflecting its mission to advance a just and sustainable society.

The Jim Flynn Outstanding Corporation Award, presented annually by NALMS, honors the corporation that has made significant contributions to advancing lake management goals. This award emphasizes the importance of facilitating information exchange, promoting public awareness of lake ecosystems, and supporting management programs at all levels. Eligible nominations can come from any individual or entity, focusing on achievements in lake and reservoir management. Notably, current NALMS board members and awards committee members are excluded from eligibility.

The NALMS Achievement Awards: Secchi Disk Award recognizes outstanding contributions to lake management by its members. NALMS aims to unite citizens, scientists, and professionals to ensure the protection and management of lakes and reservoirs. This prestigious award is open to NALMS members, with nominations encouraged from any individual or entity. However, current board and committee members are ineligible. The award celebrates those who significantly advance NALMS's goals and objectives in fostering lake ecosystem awareness and management.

The Broadcasters Foundation of America Monthly Grant provides essential financial assistance to broadcasters facing acute hardships due to serious illnesses or accidents. This initiative aims to support those who have dedicated significant years to the broadcasting profession, ensuring they receive medical aid and relief from financial burdens. Eligible applicants can apply for monthly grants if they meet specific employment and hardship criteria, helping them navigate difficult times with dignity and support.

The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) aims to support high-risk, multi-center clinical studies by facilitating early peer review and assessment of study designs. This program helps in the development of necessary operational documents and essential elements for conducting hypothesis-driven studies focused on diseases relevant to NIDDK. Applications are due by 5:00 PM local time, and consulting with NIDDK staff is strongly encouraged.

The Ethel Strickarz Memorial Scholarship aims to address community needs through educational support in special education and related fields. Funded by the Community Foundation of Elmira-Corning and the Finger Lakes, it encourages students pursuing careers in human services, nursing, psychology, speech pathology, or therapy. This scholarship reflects a commitment to holistic community development by fostering future professionals dedicated to improving lives and addressing urgent societal challenges.

The Center for Family Engagement Healthy Minds Fellowship, organized by the National PTA, invites active PTA leaders to enhance their mental health expertise over a 12-month cohort starting January 2026. Participants will receive a $1,500 stipend and engage in developing actionable plans to improve mental health initiatives in schools. This fellowship aims to empower leaders through workshops and collaborative efforts, fostering a supportive environment for mental wellness in educational settings.

Hungry for Music

The Hungry for Music story began in 1992, when Founder and Director Jeff Campbell (in photo) organized a street musician concert to benefit the homeless. Within three years, he formed a 501(c)(3) nonprofit organization, dedicated to expanding opportunities in music for children.

Since then, Hungry for Music has placed more than 27,000 instruments into the hands of aspiring musicians. Children whose trajectory has been altered by the uplifting and life-changing gift of music.

We've delivered everything from guitars and trombones to violins and xylophones to kids in 50 states and 35 countries.

We collect and redistribute more than 2,000 instruments annually and, in our 31-year journey, we've become a full-time force for good in the musical community.

Request an Instrument

Hungry for Music collects and distributes instruments including brass, woodwinds, strings, electric keyboards, drums and other percussion, as well as amps and accessories.

Who Hungry for Music Helps

• Music teachers at Title One schools who identify children who cannot participate because of lack of funding.
• Music directors at innovative after-school music programs.
• Social workers who have young clients who would benefit from music therapy.

We only accept requests from public school music teachers, administrators, after-school/summer music program directors, and social workers. 

In our history, we have supported music programs in 40 different countries through stateside sponsors (i.e. business, school, church). We do not accept requests directly from international programs.

After-School & Summer Programs

Hungry for Music supports more than three dozen after-school/summer music programs annually across the United States. To be added to our distribution, a site visit is required.

The Ashtabula Foundation offers grants up to $3,000 for Youth Enrichment programs aimed at supporting youth aged 6-18 in Ashtabula County. These grants focus on initiatives that foster personal development, leadership, and educational growth. Eligible organizations must have a 501(C)(3) status and serve the local community, with funding decisions made promptly by a review committee. This initiative aims to enhance youth skills and well-being through various programs.

The Rural Opioid Technical Assistance Centers program aims to provide essential training and technical assistance to combat opioid and stimulant misuse in rural areas. With 10 Regional Centers and a National Coordinating Office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders. This program anticipates awarding 11 new grants to enhance community health and safety in addressing polysubstance use challenges.

The NIH is offering access to biospecimens from the ABCD, HBCD, and PATH studies to promote research on health and disease across a lifetime. This initiative encourages projects that utilize these samples to deepen understanding of genetic and environmental influences, particularly substance exposure. Researchers can submit proposals to maximize the scientific utility of these resources, in alignment with the goals outlined under federal health regulations.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5432 - Validating Reverse Osmosis Conductivity Profiling for Pathogen Log Reduction Value Credit

Grant Information

• Validate conductivity profiling against pathogen removal by establishing the relationship between conductivity-profile response and MS2 bacteriophage removal under intact and controlled membrane integrity-defect conditions.
• Demonstrate the robustness and applicability of conductivity profiling across representative reverse osmosis conditions, including new and aged membranes, different defect types and severities, operating conditions, variations in feedwater quality/composition/salinity, and temperature.
• Develop a validation implementation framework that defines testing procedures, log removal value calculation methods, sensitivity and performance criteria, continuous monitoring, alarm/response thresholds, and operational requirements needed to support regulatory pathogen log removal values credit for reverse osmosis.

Loene Pooler Guthrie Scholarship Fund

The Loene P. Guthrie Scholarship fund benefits music students in Benton, Linn, and Lincoln counties who plan to engage in the teaching of piano, voice, and orchestral music.

This scholarship fund promotes the teaching of piano, voice and orchestral music by aiding music students in Benton, Linn, and Lincoln Counties who plan to engage in the teaching of piano, voice, and orchestral music. Students who will graduate from Linn, Benton, or Lincoln County high schools or graduates of those high schools currently studying music at an institution of higher learning may apply. The Linn-Benton Chapter of the Oregon Music Teachers Association reviews the applications and selects individuals to perform at an audition open to the public.

The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.

The Tribal Colleges Extension Program Special Emphasis (TCEP-SE) aims to enhance community engagement through pilot projects at 1994 Institutions, targeting issues like agricultural productivity, food systems, and public health. This program is open to a wide range of Tribal colleges and universities, promoting workforce development and youth involvement in agriculture. By addressing local needs, TCEP-SE fosters community vitality and prepares the next generation of Tribal agriculture leaders.

The David Moses Bridges Scholarship honors the legacy of a renowned Passamaquoddy artist and activist, providing essential support for individuals dedicated to the preservation of Wabanaki culture, traditional arts, and environmental stewardship. This scholarship aims to foster connections between master artists and apprentices, promote research on David's impactful life and work, and protect culturally significant natural spaces. It empowers artists and scholars to continue the vital work of preserving indigenous knowledge and practices for future generations.