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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

9,000+

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$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

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9,313 Results based on applied filters

CIRI Foundation: Higher Education Scholarship

CIRI Foundation
Private
United States
Up to US $9,000
The CIRI Foundation offers the Higher Education Scholarship to support Alaska Native students pursuing post-secondary education. Scholarships provide $200 per credit hour for undergraduates and $400 for graduates, with a maximum of $9,000 per year. Eligible applicants must be CIRI shareholders or descendants, maintain a minimum 2.0 GPA, and be enrolled in accredited institutions. This initiative aims to enhance educational opportunities and promote cultural heritage.
Education - Higher Education Academic Scholarship Programs

The Andrew Lloyd Webber Initiative: University Scholarships

American Theatre Wing Inc
Private
United States
Up to US $10,000
The Andrew Lloyd Webber Initiative: University Scholarships, by the American Theatre Wing, supports high school seniors from underrepresented backgrounds with a $10,000 annual scholarship for four years. This initiative addresses financial barriers for students pursuing theatre disciplines, including performance, design, and administration. Scholars are matched with mentors and gain exclusive opportunities such as master classes. This program aims to cultivate a diverse future in theatre, ensuring that talent is nurtured and accessible to all.
Theater

CIRI Foundation: Career Technical Education Scholarship

CIRI Foundation
Private
United States
Up to US $9,000
The CIRI Foundation offers the Career Technical Education Scholarship to support Alaska Native beneficiaries pursuing post-secondary education. This scholarship provides up to $9,000 per year for educational expenses, including tuition and required supplies. Eligible applicants must be CIRI original shareholders or descendants, possess a high school diploma or GED, and maintain a minimum GPA. The foundation aims to promote self-sufficiency and the cultural legacy of Alaska Natives through education.
Academic Scholarship Programs Vocational & Trade Education

CIRI Foundation: Cap Lathrop Scholarship

CIRI Foundation
Private
United States
Up to US $2,000
The CIRI Foundation, established in 1982, promotes education and economic self-sufficiency for Alaska Natives through scholarships like the Cap Lathrop Scholarship. This award offers up to $2,000 to full-time students pursuing degrees in fields such as business, engineering, and media. Eligible applicants must be Alaska Native shareholders or descendants, maintain a minimum 3.0 GPA, and intend to work in Alaska's broadcast industry. The scholarship supports both educational and personal expenses.
Education - Higher Education Academic Scholarship Programs

Achievement Annual Scholarship

CIRI Foundation
Private
United States
Up to US $10,000
The Achievement Annual Scholarship, offered by the CIRI Foundation, supports Alaska Native students pursuing higher education. This merit-based scholarship awards up to $8,000 for one academic year, covering direct educational costs and personal expenses. Applicants must maintain a minimum 3.0 GPA and be enrolled full-time in a 4-year undergraduate or graduate program. The scholarship aims to promote academic excellence and career development while honoring the cultural legacy of Alaska Natives.
Education - Higher Education Academic Scholarship Programs

Warren Alpert Foundation: Distinguished Scholars Award

Warren Alpert Foundation
Private
United States
Unspecified amount
The Warren Alpert Foundation's Distinguished Scholars Award aims to enhance public health by funding innovative research in basic and clinical neurosciences. Nominations are invited from medical schools and research institutions in the U.S., focusing on candidates with a strong post-doctoral record. The selection process emphasizes scholarly achievements, scientific proposals, and letters of recommendation. A total of five awards will be granted to deserving scholars, fostering significant advancements in neuroscience.
Neuroscience

21st Century Fellowship: Specialized Fellowship

Society for Ethnomusicology
Private
Canada, United States
US $7,500
The 21st Century Fellowship: Specialized Fellowship, offered by the Society for Ethnomusicology, aims to enhance ethnomusicological research by providing $7,500 awards to two Ph.D. students for dissertation fieldwork. Eligible applicants must achieve ABD status and conduct a minimum of six months of full-time research. Preference is given to onsite fieldwork and students from marginalized groups or those with limited funding for their research.
Music

Retail Food Safety Regulatory Association Collaboration CAP (356048)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $4,000,000
The Retail Food Safety Regulatory Association Collaboration CAP aims to enhance retail food protection in the U.S. by renewing a cooperative agreement that promotes collaboration among non-profit organizations and educational institutions. This initiative focuses on reducing food-borne illnesses through research and the advancement of best practices in retail food safety. By leveraging local and state resources, the program seeks to effectively mitigate food safety risks and improve public health outcomes.
Food Safety

Greater Cincinnati African American Scholarship Fund

Greater Cincinnati Foundation
Private
United States
US $2,000 - US $10,000
The Greater Cincinnati African American Scholarship Fund, administered by the Greater Cincinnati Foundation, offers scholarships for high school seniors in the Greater Cincinnati area. With awards ranging from $2,000 to $10,000, the program aims to support students pursuing higher education. Since its inception in 2002, it has awarded over $170,000 in scholarships, empowering local youth to achieve their academic goals and contribute positively to their communities.
Black American Services

On My Way to Kindergarten Program

The Molina Foundation
Private
United States
Unspecified amount in in-kind support
The On My Way to Kindergarten Program offers essential resources to prepare children aged 3-5 for kindergarten. Developed with input from educators, it includes a bilingual activity book and online access to games, songs, and crafts in both Spanish and English. Funded by The Larry and Helen Hoag Foundation, this initiative aims to empower at-risk children and their families, ensuring they have the tools needed for a successful transition into school.
Education - Preschool / Early Learning Early Childhood Development

Michigan Sugar Company FFA Mini-Grant

Michigan Sugar Company
Corporate
United States
US $500 - US $3,000
The Michigan Sugar Company FFA Mini-Grant aims to support FFA chapters in advancing agricultural education within its growing region. Grants between $500 and $3,000 will be awarded to eligible institutions, focusing on establishing new chapters and enhancing educational resources. Applications are welcomed from any FFA chapter or school district committed to agricultural education. Preference will be given to proposals that include matching funds. This initiative reflects Michigan Sugar Company's dedication to community involvement and responsible growth.
Agricultural Education

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) (358090)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative: Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting rigorous pain research. This initiative promotes interdisciplinary partnerships and enhances the research environment for health professional trainees. Key deadlines include October 28, 2025, and October 27, 2026, for standard applications, and November 24, 2025, and November 23, 2026, for AIDS-related applications. Letters of Intent are encouraged 30 days prior to the due date.
Chronic / Acute Pain Anesthesia and Pain Medicine

NLN Nursing Education Scholarship Award

National League For Nursing Inc
Private
United States
Up to US $8,000
The NLN Nursing Education Scholarship Award offers up to $8,000 annually to support nurse educators pursuing advanced degrees. As the first organization dedicated to this cause, the NLN Foundation for Nursing Education aims to strengthen the nursing workforce in the U.S. and globally. Eligible candidates are NLN members and must be enrolled in accredited master's or doctoral programs, having completed at least one year of study. This initiative is vital for advancing nursing education and improving healthcare outcomes.
Nursing

Nourishing Neighbors Innovation Incubation Fund RFP

The Albertsons Companies Foundation
Corporate
United States
Up to US $300,000
The Nourishing Neighbors Innovation Incubation Fund RFP invites organizations to submit innovative proposals aimed at ending hunger. With flexible funding ranging from $50,000 to $300,000, this initiative encourages diverse ideas, whether small or large-scale. Organizations are required to have a panel of advisors with lived experience and must operate within the U.S. This grant focuses on creating sustainable solutions, ensuring communities can achieve self-sufficiency in food access.
Food Access & Hunger

Researcher Connection Program

Uplifting Athletes Inc
Private
Canada, United States
Up to US $1,450
The Researcher Connection Program by Uplifting Athletes Inc. supports travel expenses for rare disease researchers and doctoral students, fostering connections within the rare disease community. It emphasizes health equity by reserving at least 20% of funding for underrepresented researchers. Qualified applicants can receive up to $1,450 for travel costs related to attending relevant conferences and events, enhancing collaboration and awareness in the rare disease field.
Rare Diseases

NLN Steve Cerame Nurse Educator Scholarship Award

National League For Nursing Inc
Private
United States
US $8,000
The NLN Steve Cerame Nurse Educator Scholarship Award supports aspiring nurse educators by providing up to $8,000 annually for master's or doctoral students. This award honors the legacy of NLN's former CFO and aims to facilitate the education of future nursing faculty. Eligible candidates must be NLN members and have completed at least one year of their program. The scholarship focuses on enhancing the nursing workforce and advancing educational excellence in nursing.
Nursing

MFA Fellowship

Dedalus Foundation Inc
Private
United States
Up to US $15,000
The MFA Fellowship, funded by the Dedalus Foundation, provides a $15,000 stipend to final-year students graduating from MFA programs in Painting and Sculpture in the U.S. Annually, four fellowships are awarded based on nominations from department chairpersons, allowing institutions to nominate two candidates each. Nominees must graduate in the following spring semester and submit application materials including work samples and a biographical statement. This initiative supports emerging artists in their professional development.
Fine Art

Health Services Research Grants

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Health Services Research Grants, offered by the Foundation for Physical Therapy Research, focus on enhancing physical therapy services through evidence-based studies. Researchers are encouraged to explore areas such as therapy utilization, cost-effectiveness, and access barriers using rigorous methodologies. Proposals must align with the 2023 APTA Research Agenda, addressing topics that improve patient outcomes and care delivery, particularly in underserved populations. This initiative aims to elevate the role of physical therapists and optimize healthcare access.
Physical Therapy

Earl and Jane Ferguson Scholarship Fund

The Oregon Community Foundation
Private
United States
Unspecified amount
The Earl and Jane Ferguson Scholarship Fund provides financial support to graduates of Klamath County high schools who wish to pursue higher education across the United States. This initiative aims to empower local students by making education more accessible, thereby fostering academic growth and community development. The fund is managed by The Oregon Community Foundation, a private organization dedicated to enhancing educational opportunities for deserving individuals.
Academic Scholarship Programs Education - Higher Education

Disaster Resilience Program Fellowship

Equal Justice Works
Private
United States
More than US $7,000
The Disaster Resilience Program Fellowship supports low-income communities affected by disasters by mobilizing lawyers and law students to provide free civil legal aid. This initiative ensures access to essential legal services, helping families navigate recovery barriers. Attorney Fellows receive a salary while Student Fellows earn a stipend for their service. Participants engage in outreach, build community relationships, and receive comprehensive training to enhance their legal skills, contributing to the resilience of affected communities.
Legal Services Disaster Relief / Humanitarian Aid

Jonathan and Barbara Silver Foundation - Grant for Sculpture

Jonathan and Barbara Silver Foundation
Private
United States
US $20,000
The Jonathan and Barbara Silver Foundation offers a $20,000 grant annually to support sculptors and writers on sculpture, promoting creativity and artistic development. This grant is open to U.S. citizens and permanent residents, as well as O-1 Visa holders, who demonstrate a strong commitment to sculpture. Eligible expenses include materials, research, and living costs. The foundation values diversity and does not discriminate based on background, ensuring a wide range of applicants can apply.
Fine Art

Darlene Hooley Scholarship for Oregon Veterans

The Oregon Community Foundation
Private
United States
Unspecified amount
The Darlene Hooley Scholarship for Oregon Veterans supports military veterans who served in the post-9/11 conflict, prioritizing those in the Oregon National Guard and Reservists. This scholarship is designed for students enrolling in higher education institutions across the United States, providing financial assistance to those who have bravely served their country.
Military & Veterans Services Academic Success & Enrichment

Fund for Teachers Fellowship

Fund For Teachers
Private
United States
Unspecified amount
The Fund for Teachers Fellowship empowers educators to design personalized learning experiences that enhance their professional skills and student engagement. With over 20 years of experience, this initiative has supported more than 10,000 teachers, enabling them to transform their classrooms through unique fellowship opportunities. Eligible applicants include full-time teachers in the U.S. who have at least three years of teaching experience and plan to return to the classroom after their fellowship. This fellowship fosters innovative teaching practices and collaborative growth.
Education - K through 12 Teacher Development & Training

UHCCF Medical Grant

Unitedhealthcare Children's Foundation
Private
United States
US $5,000 - US $10,000
The UHCCF Medical Grant provides financial assistance to families with children under 16 years old who need access to medical services not fully covered by insurance. The grant offers up to $5,000 per year, with a lifetime maximum of $10,000. Families can apply regardless of their insurance provider, and the grant covers a wide range of medical expenses, ensuring children receive essential health care. Applicants must meet specific income and eligibility criteria to qualify for funding.
Children With Disabilities

George L. Mosse Prize in European Intellectual and Cultural History

American Historical Association
Association/Society
United States
US $1,000
The George L. Mosse Prize, awarded by the American Historical Association, honors exceptional works in European intellectual and cultural history since 1500. This prestigious award, with a prize amount of $1,000, recognizes scholarly distinction and originality. Eligible submissions include books published in 2024, with a focus on research accuracy and literary merit. Winners will be announced on the AHA website in October 2025 and celebrated at the January 2026 AHA annual meeting in Chicago.
European History Community Culture & Heritage

NACRJ Mini-Grants

National Association of Community and Restorative Justice
Private
United States
Up to US $500
The NACRJ Mini-Grants provide funding of up to $500 for projects promoting community and restorative justice. Launched in 2016, the initiative has allocated over $60,000 to support NACRJ members nationwide. This unique opportunity fosters impactful projects and enhances visibility within the restorative justice community. Applications are accepted biannually, with a focus on empowering organizations and individuals committed to restorative practices. Members are encouraged to apply for this essential funding to further their meaningful endeavors.
Criminal Justice System Reform

NACRJ Impact Grant

National Association of Community and Restorative Justice
Private
United States
Up to US $3,000
The NACRJ Impact Grant, initiated in 2016, has provided over $60,000 to NACRJ members to support community and restorative justice projects. This grant is available annually, offering up to $3,000 to members for innovative initiatives that foster community impact. By applying, members can gain funding, visibility, and networking opportunities within the NACRJ and the broader restorative justice community, helping to empower meaningful projects that align with restorative justice principles.
Criminal Justice System Reform

Large Grants for Nonprofit Organizations in South Carolina Highlights

Looking for large grants for nonprofit organizations in South Carolina?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

41 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081