Best Large Grants for Nonprofit Organizations in South Carolina

The Women’s Shelters Grant, provided by the AKC Humane Fund, offers financial assistance to domestic abuse shelters that accommodate pets. This grant aims to empower shelters to break the cycle of domestic violence by allowing women to keep their beloved pets during difficult times. By supporting organizations that facilitate this, the AKC Humane Fund fosters a community where both women and animals can find safety and solace together.

The AMVETS Children/Grandchildren Scholarship supports the educational aspirations of children and grandchildren of honorably discharged U.S. veterans and active military. This scholarship aims to bridge financial gaps after all federal and state assistance has been utilized. Eligible applicants must be U.S. citizens, high school seniors, and demonstrate financial need while enrolled in accredited four-year universities. Incomplete applications will be disqualified, ensuring that the award goes to deserving candidates committed to their education.

The AMVETS Spouse Scholarship offers financial support to the spouses of honorably discharged veterans and active military personnel, including National Guard and Reserves. This scholarship aims to bridge financial gaps after other federal and state resources have been exhausted. Eligible applicants must be U.S. citizens enrolled in accredited undergraduate programs, demonstrate financial need, and not be in default on federal student loans. AMVETS stands committed to empowering military families through education.

The AMVETS Veteran, Active Duty & Guard/Reserve Scholarship provides financial assistance up to $12,000 for qualified U.S. Veterans and active military members pursuing undergraduate degrees. This scholarship is designed to bridge the financial gap after all other federal and state aid has been utilized. Eligibility includes being an honorably discharged veteran or active service member, enrolled in an accredited institution, and demonstrating financial need. AMVETS is dedicated to serving those who have served our country.

Daviess County Community Foundation

The Community Foundation is a charitable resource devoted to our local community. We help people make meaningful gifts that improve life in Daviess County, Indiana today and for generations to come.

The Community Foundation can help you...

• Make a difference where it matters
• Invest in the future of the community you love
• Create greater good together

German American Bancorp Scholarship

Annual scholarship created by Peoples Bank, now German American Bancorp, to help Daviess County students pursue advanced education.

Award Amount

• $2,000

Perry County Community Foundation

The Community Foundation is a charitable resource devoted to our local community. We help people make meaningful gifts that improve life in Perry County, Indiana today and for generations to come.

The Community Foundation can help you...

• Make a difference where it matters
• Invest in the future of the community you love
• Create greater good together

J. Matthew Moore Memorial Scholarship

Annual, renewable scholarship created in memory of Matthew Moore by his wife, Lucy Goffinet, and his parents, John E. and Ann C. Moore, to help students pursuing advanced education.

Award Amount

• $1,580
• May be renewable for consecutive sophomore, junior and senior years. 
• Renewal award amounts may differ from the original award.

The AAFP Foundation's Center for the History of Family Medicine Oral History Grant offers up to $3,000 annually for oral history interviews in family medicine. Aimed at researchers, physicians, and students, it encourages the documentation of family medicine's history in the U.S. The grant supports travel and research expenses to enhance the oral history collection, ensuring a diverse representation of experiences and perspectives in the field.

The Shared Decision Making in Hemophilia Patient Care grant program, funded by Pfizer, aims to enhance patient outcomes through Quality Improvement projects that integrate shared decision-making tools into hemophilia care. This initiative encourages multidisciplinary collaboration to address healthcare disparities and empower patients in their disease management. Eligible organizations include healthcare institutions and professional schools, fostering innovative approaches to improve care for individuals living with hemophilia.

The Forecast for Clinical Trial Readiness for Rare Diseases (R21) aims to enhance the development and testing of diagnostics and therapeutics for rare diseases. This funding opportunity invites researchers to facilitate clinical trial readiness by developing rigorous biomarkers and clinical outcome measures. Through collaborative efforts with various stakeholders, NCATS seeks to improve the efficiency of moving candidate therapeutics towards clinical trials, ultimately increasing the likelihood of successful treatments for rare diseases.

Community Foundations of the Hudson Valley 

Community Foundations of the Hudson Valley (CFHV) empowers individuals, families, businesses, and organizations to fulfill their philanthropic goals through the establishment of charitable funds that support the needs of Dutchess, Putnam and Ulster counties. With over $100 million in assets, CFHV manages nearly 600 charitable funds and has distributed more than $777 million in grants and scholarships since January 2000. We lead initiatives to address urgent community needs such as food insecurity and educational challenges, offering both immediate relief and long-term support.

Wappingers Rotary Scholarship

Established by the Rotary Club of Wappingers Falls, scholarships will be awarded to graduating seniors from Roy C. Ketcham High School or who reside in the RCK area who have demonstrated involvement/leadership in community service activities and an ability to succeed in their chosen field.

Type of Award

One-time non renewable scholarship payable to school

Current High School

Roy C. Ketcham High School or resident in the RCK district

The Jim Henson Foundation offers annual grants for innovative contemporary puppet theater works, with three categories: Workshop Grants ($3,000), Production Grants ($7,000), and Family Grants ($4,000). These grants support puppet creation and performance, encouraging artistic excellence. Eligibility is primarily for IRS tax-exempt organizations, with individual artists needing a fiscal sponsor. International collaborations are welcome if the primary artist is a U.S. citizen. Grants are not available for projects based outside the U.S. or for non-puppet related activities.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Gustafson Fritz Scholarship for Women

An opportunity for female high school graduates in Shasta or Trinity County who demonstrate attributes of generosity, creativity, exemplary work ethic and kindness.

Patricia “Pat” L. Gustafson was an exceptional woman. She was known for her stewardship, generosity, creativity, exemplary work ethic and kindness. Continuing the legacy gifted to her by Pat, her “daughter”, Lynn E. Fritz, the Guftason Fritz Scholarship for Women honors her by awarding support to other women demonstrating like attributes in their journey of self-discovery, empowerment, education and community service.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Jack Schreder Scholarship Fund

The Jack Schreder Scholarship Fund honors Jack’s 65 years of work as an educator with strong interest in education, science and vocational training.

He was a graduate of Michigan State (B.A. – Economics), San Francisco State University (M.A. – School Administration) and Stanford University (Ph.D – Education and Business). He began his career as a high school teacher and coach in Michigan.

The Jack Schreder Scholarship will support scholarships to Shasta County graduating seniors pursuing Education, Science, and/or Vocational Training.

Community Foundation of the North State

The Community Foundation builds trust through relationship, integrity, and by providing safe places for donors to give their resources.

We are a nonprofit, public charity serving the people of Shasta, Siskiyou and Tehama counties, with a mission to impact the region through the power of giving.

Scholarships

The Community Foundation of the North State manages many scholarship funds that are awarded to graduating high school seniors as well as students already in an undergraduate program. Some scholarships were started by families or individuals; others by businesses or organizations. All scholarships share one important focus: helping young people reach their educational goals.

Jim Freeman, MD Memorial Scholarship

A long time military man, Dr. Freeman retired as a full colonel from the Army after many years of service active duty and reserves. He was a partner at the Redding Radiological Associates during much of his reserve military career, continuing his craft as an independent contractor at several facilities until his death in 2018.

Much of his career was spent in training other physicians, a task he greatly enjoyed. He was a very strong proponent of education of all kinds and believed all should have access to the education of their choice.

The Jim Freeman, MD Scholarship was established to benefit and support Shasta County students pursuing a degree, certification, or licensing in the medical field focused on direct patient care.

The Dr. Patricia L. Austin Family Physicians of Tomorrow Scholarship offers $10,000 in tuition assistance to medical students entering their final year. Sponsored by the AMA Foundation, this program supports a diverse group of students, including those of Eastern European descent and first-generation students. All applicants must be enrolled in accredited U.S. medical schools, ensuring equitable opportunities in pursuing their medical careers, while fostering representation in the field.

Sophia Joe Scholarship Fund

Sophia Joe graduated from Capital High School in 2023 and the University of San Diego in 2026 with a degree in Marketing and a minor in International Business. During high school, she was a four-year member of the Dance Team and served as Treasurer and Vice President of the National Honor Society, completing more than 100 hours of community service. She also worked her final two years of high school at local businesses in downtown Olympia. Throughout her academic career, Sophia earned recognition on the President’s List at South Puget Sound Community College and received the Donald R. Knauss Trustee Merit Scholarship at the University of San Diego.

Sophia’s passion for travel and global learning helped shape her vision for this scholarship. While studying abroad, she worked alongside students from diverse backgrounds, deepening her appreciation for the importance of access to opportunity. As a member of a family that has been part of the Thurston County community for more than 20 years, Sophia created this fund to support local students who work hard, demonstrate leadership, and aspire to make a positive impact.

The Sophia Joe Scholarship Fund encourages graduating seniors from Thurston County who are pursuing studies in business or a related field to develop their vision for leadership and positive change, both within their community and beyond.

Applicants will be evaluated on their impact, leadership, and vision, as demonstrated by:

• Community service involvement or a commitment to helping others.
• Leadership or responsibilities outside of school, including work, volunteering, or caring for family members.
• Thoughtfulness and vision, as demonstrated by a supplemental essay responding to the question: “What community project or initiative do you think would make the biggest positive impact in Thurston County, and why?”

The Brookreson Trust Grant aims to support financing homes for the blind and organizations that assist them. This grant is targeted towards 501(c)(3) exempt organizations across all states. The program focuses on key areas such as education, health, and human services, ensuring that vital resources are directed towards enhancing the quality of life for the visually impaired community. Grants are specifically intended for initiatives that facilitate housing and support services.

The Community Foundation of Shelby County

Our Mission

To inspire donor generosity and transform it into meaningful, lasting impact through charitable gifts.

Our Vision

To be the primary partner for donors who want to advance the community’s quality of life and capacity for excellence.

Sidney High School Alumni Scholarship

Selection based upon:

• Financial need; academic ability; community, religious, and school service; recommendations.

Must be enrolling in a trade school or pursuing a two-year or four-year degree.

Awards

• One $2,000 scholarship

We are about helping children, right here in Marietta!

Kiwanis Club of Marietta members participate in service projects, hold fundraisers, and change children’s lives in our community. In addition, club members contribute to Kiwanis International initiatives helping clubs around the world assist children with education, basic needs, and medical care.

The Kiwanis Club of Marietta was chartered March 3, 1930 - Marietta, GA.

The Kiwanis Club of Marietta has proudly established and contributed to several scholarship endowments over the years to support deserving college students in our community. These scholarships are made possible through our club's Flag Project, which places over 1,300 American flags in front of homes and businesses five times each year.

E.W. Chastain Scholarship

This is a scholarship established in 1997 by the Marietta Kiwanis Foundation. 

Selection emphasis will be placed on academic achievement and character. 

Awards

• $2500

The Columbus Foundation

In 1943, during the darkness of World War II, a group of passionate citizens, led by Columbus businessman Harrison M. Sayre, envisioned a way to improve the well-being of the community and the quality of life in central Ohio. With little more than this sound idea and faith, The Columbus Foundation was established.

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

CBC Charities Scholarship

Continental Building Co. (CBC) is a full-service construction management firm headquartered in Columbus, OH, with an office in Pittsburgh, PA. During our 35 year history, CBC has grown and evolved dramatically, investing in our people and the most effective technologies for communication and construction – while spanning geographically from coast to coast. We work with national developers and private clients to build facilities that affect lives daily … places where people live, work, stay and shop.

WindSwell Foundation: Scholarship- Additional Licensing

Managed by the Community Foundation of Greater Fort Wayne, this scholarship opportunity is for up to $2,500 per year for any Special Educator seeking additional licensing.

Enhancing the Flavor of Plant-based & Fermentation-derived Proteins

As global demand for protein continues to rise, this funding opportunity can help diversify protein sources, strengthen the sustainability of food and agriculture supply chains and contribute to a safer, more resilient global food system. Improving the functionality and flavor of plant-based and fermentation-derived proteins can increase consumer acceptance, open new markets for crops, create value-added opportunities for farmers and processors, enhance farmland health and support economic growth.

To drive such innovation the Foundation for Food & Agriculture Research (FFAR) and the Good Food Institute (GFI) have joined forces to support plant-based and fermentation-enabled protein ingredient optimization.

The long-term success of plant-based and fermentation-enabled protein foods depends not only on sustainability and cost but also on their ability to deliver a compelling eating experience. By advancing research in ingredient design, enrichment methods and formulation strategies, we can accelerate progress toward high-protein foods that meet or exceed consumer sensory expectations.

Flavor, inclusive of both taste and aroma, remains a critical barrier to consumer acceptance. While early innovation has made progress, many products on the market still face challenges with off-flavors or insufficient desirable flavors. Improving flavor emerged as a key recommendation from the joint FFAR-GFI global call for ideas and workshop, summarized in The Priorities for Plant-based and Fermentation-enabled Protein Ingredient Optimization Convening report.

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Coach Dave Gray Scholarship Fund

The Coach Dave Gray Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships for students who plan on pursing post-secondary education. This scholarship fund was established by John and Shana Mackie in 2017 with funds raised through their 2017 “Party for a Purpose”, an annual party for their friends and family with the goal of raising awareness for a different worthy local ministry or cause each year. John and Shana named the fund in honor of Coach Dave Gray who has dedicated his career to working with youth in Western Pennsylvania. Through his classes, camps, training and other activities, Coach Dave impacts the lives of thousands of kids in a positive way. Dave’s programs instill confidence, self-esteem, promote a healthy, active lifestyle and are fun for kids. This scholarship fund will honor Coach Dave’s commitment to the community and help benefit students from Western Pennsylvania for years to come.

Award Type: Single-Year Award

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Comptaro, Elden, Lewis Combined Scholarship Funds

The William C. Comptaro Educational Fund, the Laura E. Elden Educational Trust and the Frances L. Lewis Memorial Scholarship Fund were created at The Pittsburgh Foundation to provide scholarships to graduating high school seniors who are residents of Allegheny County, PA planning on pursuing post-secondary education.

Award Type: Single Year Award

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Dorothy & Richard Barr Westmoreland County High School Scholarship Fund

The Dorothy and Richard Barr Scholarship Fund was created at The Community Foundation of Westmoreland County to provide scholarship support to Westmoreland County High School students who have demonstrated community leadership and strong academic performance. The applicant must have a cumulative grade point average of 3.5 or above. The applicant must also show community leadership in the form of volunteer activities inside and outside of school.

Award Type: Single-Year Award

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Dr. Roy D. Hoffman Scholarship Fund

The Dr. Roy D. Hoffman Scholarship Fund of The Pittsburgh Foundation was created to assist students in Bedford and Fulton Counties, Pennsylvania in acquiring post-secondary education.

Award Type: Single Year. Previous recipients are encouraged to re-apply.

The Edward J. Ferri Memorial Scholarship Fund, established by The Pittsburgh Foundation, provides financial support to students in Westmoreland County, including employees and their children from Ferri Enterprises. This fund aims to assist graduating seniors from local high schools and has expanded eligibility to include all graduates from Allegheny, Somerset, or Westmoreland County. With a focus on students pursuing vocational, technical or college education, this scholarship emphasizes financial need and community involvement.