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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

9,000+

Available grants

$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

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9,315 Results based on applied filters

Sleep Research Program for Advancing Careers Grant

American Academy Of Sleep Medicine Foundation
Private
United States
Unspecified amount in in-kind support
The Sleep Research Program for Advancing Careers, funded by the American Academy Of Sleep Medicine Foundation, aims to develop early-career sleep scientists through a structured grant writing curriculum. Participants receive mentorship and training to submit competitive federal career development grants, such as NIH K awards. The program includes lectures and grant review sessions, ensuring applicants complete their proposals successfully. Additionally, a travel scholarship is offered for in-person meetings, fostering collaboration and growth in sleep research.
Sleep Medical Education & Professional Training

AMA Foundation: Physicians of Tomorrow Scholarship

American Academy Of Sleep Medicine Foundation
Private
United States
US $10,000
The AMA Foundation's Physicians of Tomorrow Scholarship offers four $10,000 awards for medical students pursuing sleep medicine in 2025. Eligible applicants must be entering their final year, demonstrate financial need, and express interest in sleep medicine in their personal statement. This scholarship aims to support students dedicated to excellence in medical education and the advancement of sleep medicine as a vital field in healthcare.
Sleep Medical Education & Professional Training

AASM Foundation Disaster Relief Fund

American Academy Of Sleep Medicine Foundation
Private
American Samoa, Canada +5 more
Unspecified amount
The AASM Foundation Disaster Relief Fund, established in 2005, provides essential financial aid to AASM accredited sleep centers impacted by natural disasters. By supporting these centers, the fund ensures that medical care remains accessible to patients during crises. Past funding has assisted centers after events like Hurricane Katrina and the 2010 Haiti earthquake, helping them recover and restore operations quickly. This initiative highlights the commitment to maintaining patient care in the face of adversity.
Sleep Disaster Relief / Humanitarian Aid

Daily Bread Grants

Evangelical Lutheran Church in America
Private
Caribbean, United States
US $500
The Daily Bread Grants, offered by the Evangelical Lutheran Church in America, aim to support congregations with feeding ministries. Starting from November 1st, organizations can apply for $500 grants to help alleviate hunger in their communities. Priority is given to rural ministries, and applications will be accepted until funds are exhausted or until November 15th. This initiative not only provides immediate assistance but also encourages further financial support for food-based services.
Food Access & Hunger

David Roy Kovacs Scholarship

The Community Foundation of Greater New Britain
Private
United States
US $500 - US $30,000
The David Roy Kovacs Scholarship, offered by the Community Foundation of Greater New Britain, supports local high school graduates from New Britain who plan to pursue further education at community colleges, trade schools, or vocational schools. This scholarship emphasizes financial need as determined by the FAFSA and is intended to help students acquire the skills necessary for career success and economic independence, fostering a brighter future for the community.
Education - Higher Education Vocational & Trade Education

Mary Means Leadership Award

National Main Street Center Inc.
Private
United States
US $1,000
The Mary Means Leadership Award, introduced by Main Street America in 2019, celebrates outstanding leaders in local Main Street organizations. This annual award recognizes the vital role of leadership in revitalizing historic downtowns and enhancing community life. Nominees must be active members of Main Street America, showcasing their commitment to community, innovation, and collaboration. The award highlights the importance of diverse leadership in advancing local economic development and preserving cultural heritage across the nation.
Economic Services & Development Civic Leadership Development

Ann and Reno Arsego Medical Scholarship

Northwest Connecticut Community Foundation
Private
United States
Approximately US $15,000
The Ann and Reno Arsego Medical Scholarship, offered by the Northwest Connecticut Community Foundation, supports Torrington or Litchfield residents pursuing careers in the medical field. With an average award of $15,000, this scholarship is designed for students accepted into a college or university with a pre-medical program. Recipients can only receive the scholarship once in their lifetime, making it a valuable opportunity for aspiring healthcare professionals.
Medical Education & Professional Training Academic Scholarship Programs

BURGER KING Scholars: James W. McLamore WHOPPER® Scholarship

Burger King Mclamore Foundation Inc
Private
Canada, Guam +2 more
US $60,000
The BURGER KING Scholars: James W. McLamore WHOPPER® Scholarship provides financial support to deserving students across North America. With a focus on leadership and financial need, up to three scholarships of $60,000 are awarded annually. Eligibility extends to high school seniors and employees of Burger King, promoting empowerment through education. The program, administered by Scholarship America, has awarded nearly $64 million to over 55,000 students, emphasizing the importance of education in achieving one’s potential.
Academic Scholarship Programs Education - Higher Education

SAGES Education & Research Foundation Grants

Sages Education And Research Foundation
Private
United States
US $1,000 - US $100,000
The SAGES Education & Research Foundation Grants promote advancements in minimally invasive surgical techniques aiming to reduce patient trauma and recovery time. They offer competitive funding ranging from $1,000 to $100,000, with a total allocation of $500,000 to $600,000 this year. Eligible applicants include 501(c)(3) or 501(c)(6) organizations aligned with the Foundation's mission. Grants are awarded annually, requiring reapplication for multi-year support.
Surgery Medical Education & Professional Training

Wyoming County Community Health Foundation Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Wyoming County Community Health Foundation Scholarship

Established by the Wyoming County Community Health Foundation to provide tuition assistance to a graduating high school senior who resides in Wyoming County and will major in the health care field.

Education - Higher Education Medical Education & Professional Training

Darlene Hooley Scholarship for Oregon Veterans

The Oregon Community Foundation
Private
United States
Unspecified amount
The Darlene Hooley Scholarship for Oregon Veterans supports military veterans who served in the post-9/11 conflict, prioritizing those in the Oregon National Guard and Reservists. This scholarship is designed for students enrolling in higher education institutions across the United States, providing financial assistance to those who have bravely served their country.
Military & Veterans Services Academic Success & Enrichment

Health Services Research Grants

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Health Services Research Grants, offered by the Foundation for Physical Therapy Research, focus on enhancing physical therapy services through evidence-based studies. Researchers are encouraged to explore areas such as therapy utilization, cost-effectiveness, and access barriers using rigorous methodologies. Proposals must align with the 2023 APTA Research Agenda, addressing topics that improve patient outcomes and care delivery, particularly in underserved populations. This initiative aims to elevate the role of physical therapists and optimize healthcare access.
Physical Therapy

Adam Liepinis Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony.

Adam Liepinis Memorial Scholarship

Established by the family of the late Adam Liepinis to provide tuition assistance to a graduating senior from Susquehanna or Wyoming counties, who will attend a post-secondary degree program with priority given to a student majoring in welding or automotive technology.

Vocational & Trade Education Education - Higher Education

Matthew VanFleet Memorial Automotive Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Matthew VanFleet Memorial Automotive Scholarship

Established by Matthew’s parents and his sister in memory of Matt who passed away in an automobile accident. The scholarship provides assistance to a student who will study automotive technology. The scholarship is available to students from all the school districts in Susquehanna and Wyoming Counties.

Education - Higher Education Vocational & Trade Education

Julia A. Frystak Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Julia A. Frystak Memorial Scholarship

In memory of Julia Frystak, a Montrose student who passed away due to injuries sustained in an accident. Provides a post-secondary scholarship to a high school graduate who excels in academics and participates in athletics.

Education - Higher Education Sports & Athletics

Ted & Shannon Skokos Foundation Grant

Ted and Shannon Skokos Foundation
Private
United States
Unspecified amount
The Ted & Shannon Skokos Foundation Grant, established in 2008, supports nonprofit organizations in arts, education, humanity, and faith. It prioritizes visionary leadership, community impact, sustainability, organizational strength, and collaboration. The foundation seeks to fund eligible 501(c)(3) nonprofits that align with its mission and positively influence communities, particularly in Dallas, Texas, and Arkansas, where the founders have personal connections.
Art & Culture Human & Social Services Education +1 more

Mariano and Maria Lampazzi Fiaschi Memorial Scholarship

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Mariano and Maria Lampazzi Fiaschi Memorial Scholarship

Established by Colonel Peter Fiaschi in memory of his parents, this scholarship is awarded to a graduating student from Susquehanna Community School District who intends to pursue a major in healthcare. The scholarship provides financial support for up to four years of college, contingent upon the recipient maintaining a minimum GPA of 3.0 and remaining in good standing within an accredited healthcare program.

Education - Higher Education Medical Education & Professional Training

The Paramo Foundation Scholarship Award

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Scranton Area Community Foundation

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

Scholarships

We are honored to be the stewards of over 100 scholarship funds established by philanthropically-minded individuals in our community. Generous donors entrust us to connect them to dynamic students to provide financial resources for their education through scholarships. Our donors establish scholarship funds with criteria they wish to be met by applicants. Our scholarship committee considers the criteria, evaluates the submitted applications, and chooses the best candidates for each scholarship.

The Paramo Foundation Scholarship Award

The Paramo Foundation Scholarship Award is awarded annually to low income students attending a college or university focused on the trades, including but not limited to, cosmetology programs. The scholarship will provide a full scholarship for one year at a trades school.

Education - Higher Education Vocational & Trade Education

Earl and Jane Ferguson Scholarship Fund

The Oregon Community Foundation
Private
United States
Unspecified amount
The Earl and Jane Ferguson Scholarship Fund provides financial support to graduates of Klamath County high schools who wish to pursue higher education across the United States. This initiative aims to empower local students by making education more accessible, thereby fostering academic growth and community development. The fund is managed by The Oregon Community Foundation, a private organization dedicated to enhancing educational opportunities for deserving individuals.
Academic Scholarship Programs Education - Higher Education

MFA Fellowship

Dedalus Foundation Inc
Private
United States
Up to US $15,000
The MFA Fellowship, funded by the Dedalus Foundation, provides a $15,000 stipend to final-year students graduating from MFA programs in Painting and Sculpture in the U.S. Annually, four fellowships are awarded based on nominations from department chairpersons, allowing institutions to nominate two candidates each. Nominees must graduate in the following spring semester and submit application materials including work samples and a biographical statement. This initiative supports emerging artists in their professional development.
Fine Art

Gibson Foundation Donation Request

Gibson Gives
Private
United States
Unspecified amount
The Gibson Foundation, now known as Gibson Gives, is dedicated to enhancing lives through music by supporting 501(c)(3) organizations. Their mission is to inspire and amplify the power of music through guitars for all generations. With a commitment to music education and wellness, Gibson Gives is making a positive impact worldwide, ensuring that music continues to shape the lives of musicians and enrich communities. Donations are reviewed monthly, requiring a minimum of four weeks for processing.
Music Education

Edwards Lifesciences Foundation Grants

Edwards Lifesciences Foundation
Private
United States
Unspecified amount
The Edwards Lifesciences Foundation Grants program aims to improve the health of underserved communities by supporting initiatives focused on education, screening, and treatment of cardiovascular disease. The Foundation seeks to enhance care access for patients, promote awareness of heart health, and foster community engagement through volunteer opportunities. By 2025, the goal is to positively impact the lives of 2.5 million patients affected by structural heart issues. The program emphasizes collaboration and innovation in healthcare.
Cardiovascular Diseases & Systems

National Glaucoma Research RFP: Standard Awards

BrightFocus Foundation
Corporate
United States
Up to US $150,000
The National Glaucoma Research Program, funded by BrightFocus Foundation, aims to support groundbreaking research in glaucoma. Established in 1978, the program has awarded over $35 million to 32 projects focusing on understanding and treating this disease. The Standard Awards provide $150,000 over two years for researchers with preliminary data to further their work. Eligible institutions must be non-profit and demonstrate their tax-exempt status to receive funding, fostering innovative solutions for glaucoma treatment.
Eye Diseases & Disorders

NLN Steve Cerame Nurse Educator Scholarship Award

National League For Nursing Inc
Private
United States
US $8,000
The NLN Steve Cerame Nurse Educator Scholarship Award supports aspiring nurse educators by providing up to $8,000 annually for master's or doctoral students. This award honors the legacy of NLN's former CFO and aims to facilitate the education of future nursing faculty. Eligible candidates must be NLN members and have completed at least one year of their program. The scholarship focuses on enhancing the nursing workforce and advancing educational excellence in nursing.
Nursing

Clonts Anderson Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $1,500

Community Foundation of the Ozarks

The Community Foundation of the Ozarks (CFO) provides philanthropic leadership to build stronger communities. Our mission is to enhance the quality of life in our region through resource development, community grantmaking, collaboration and public leadership.

We help donors achieve their philanthropic goals through professional management and investment of charitable funds. We work with nonprofit organizations to help them fulfill their missions through fund administration, grantmaking and learning opportunities. We award scholarships to deserving students to help them achieve their educational goals.

Clonts Anderson Scholarship

  • Graduating high school senior from El Dorado Springs High School who is female
  • GPA between 2.5 and 3.5; submit transcript
  • Must be applying to a two-year or four-year accredited college, university or vocational school
  • Demonstrate financial need; submit FAFSA-SAI form
  • Describe participation in community service, school activities
  • Essay required

Education - Higher Education Vocational & Trade Education

Chaim Schwartz Foundation Grant

Chaim Schwartz Foundation
Private
United States
US $500 - US $5,000
The Chaim Schwartz Foundation Grant supports initiatives that preserve and enrich Yiddish language, culture, theater, and art. Established in memory of Sandra Schwartz Tangri, the foundation aims to continue the rich social justice heritage of Yiddishkeit. Proposals can be project-specific or for general support, with grant amounts ranging from $500 to $5,000, and the application process is designed to be straightforward for non-profit organizations.
Jewish Culture

Aaaron Ardoin Foundation Research & Education Grants

San Antonio Area Foundation
Private
United States
Unspecified amount
The Aaaron Ardoin Foundation offers Research and Education Grants aimed at supporting organizations that address the needs of individuals and families affected by sickle cell disease. With a focus on funding programs that advance awareness, treatment, and care, the foundation reviews grant requests biannually. Eligible applicants must be 501(c)(3) organizations dedicated to initiatives directly benefiting the sickle cell community, ensuring that funds are utilized efficiently and effectively.
Hematological Systems

Large Grants for Nonprofit Organizations in South Carolina Highlights

Looking for large grants for nonprofit organizations in South Carolina?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

41 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081