Best Large Grants for Nonprofit Organizations in South Carolina

The Wish You Well Foundation Grant supports U.S. non-profit organizations focused on adult literacy. Grants typically range from $200 to $10,000 and require proof of 501(c)(3) status. The foundation prioritizes programs that foster adult and family literacy. Organizations are encouraged to apply for funding that aligns with their specific needs. The Foundation communicates via email regarding proposal receipt and funding decisions, ensuring timely updates to applicants.

The National Endowment for Financial Education Grant supports innovative research aimed at enhancing the public's financial well-being. This grant prioritizes studies that address financial literacy, systemic inequality, and the effectiveness of financial education among U.S. youth. Eligible applicants include researchers from nonprofit organizations or educational institutions. The funding process involves multiple phases, including evaluations and proposals, ensuring that impactful projects receive necessary support. NEFE aims to foster rigorous research that contributes significantly to financial education.

The Crossroads Hospice Charitable Foundation is committed to enhancing community awareness of hospice and palliative care services. It supports nonprofit organizations that provide end-of-life care and grief recovery resources. Through educational initiatives and financial grants, the Foundation aims to promote excellent hospice care and assist caregivers. Organizations eligible for funding must be 501(c)(3) nonprofits, and the Foundation does not fund administrative costs or general funding. Grant applications are accepted once per year.

The Jordan Fund, established by John & Kelly Olerud in 2003, is dedicated to supporting children with special needs and their families. This grant-making organization assists children with substantial disabilities up to age twenty-one, covering costs for respite, therapy, and essential equipment not provided by insurance. By funding 501(c)(3) organizations, the Jordan Fund aims to enhance the quality of life for these children and their families.

Our Mission

The Community Foundation’s mission is to improve the quality of life in Greater Kansas City by increasing charitable giving, educating and connecting donors to community needs they care about, and leading on critical community issues.

Scholarships

We offer hundreds of different scholarships for students in and around Kansas City.

Todd Epsten Memorial Scholarship

This opportunity was established in 2014 in honor of Major Brands’ third-generation leader, Todd H. Epsten, who lost his brave battle with brain cancer in 2012. The scholarship provides aid to several students each year, whose academic efforts and community involvement reflect Todd’s commitment to “building our business by building the communities we serve.” Students must be a current full-time employee or spouse/domestic partner, child or grandchild of a current full-time employee of Clever Little Girl, LLC; Clever Little Girl Foundation; or Eagle Brands Sales who will be or are attending a community college, professional program, undergraduate, graduate, or postgraduate program at an accredited college.

The Reeves Foundation supports research aimed at understanding and treating macular degeneration, a condition that has personally affected the founder's family. Established in 1997, the foundation allocates 50% of its grants to research and the other half to local charities in Columbus, Indiana. Nonprofit organizations exempt under IRS code 501(c)(3) are eligible to apply, but funds cannot be used for administrative costs. The foundation prioritizes equipment purchases and partnerships with other funding sources.

The Craig H. Neilsen Foundation's Creating Opportunity & Independence Grant supports programs and research that enhance the quality of life for individuals with spinal cord injuries (SCI). It welcomes applications from nonprofit organizations and rehabilitation facilities in the U.S. and Canada, focusing on projects that foster independence, community participation, and capacity-building. Priority is given to initiatives that demonstrate broad impact and involve individuals with SCI, ensuring their needs and perspectives shape the proposed activities.

The Alcon Foundation Grant aims to enhance eye care services and improve patient access, with a focus on educational and training programs. The foundation also supports cultural and community development initiatives that uplift the quality of life in areas where Alcon operates, including cities like Fort Worth, Houston, and Irvine. However, it does not fund non-501(c)(3) organizations, athletic leagues, or fundraising events, among other exclusions.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to either a graduating senior pursuing a post-secondary degree, or a currently matriculating student already so enrolled, who lives in Lackawanna or Wayne county and who is pursuing a degree or certificate in environmental science or a related field.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from Scranton or West Scranton High School who demonstrates an interest in the arts.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating female from Scranton or West Scranton High School who is a resident of Lackawanna County.

The FWW Research Award supports innovative, short-term studies aimed at enhancing women's health, particularly in areas such as cardiovascular disease, female cancers, and hormonal impact on health. Eligible applicants include MDs and PhDs affiliated with accredited institutions. The program prioritizes research with direct clinical applications and seeks proposals that promise to attract additional funding for further study. Notably, sociological research is excluded from funding consideration.

The Disaster Resilience Program Fellowship supports low-income communities affected by disasters by mobilizing lawyers and law students to provide free civil legal aid. This initiative ensures access to essential legal services, helping families navigate recovery barriers. Attorney Fellows receive a salary while Student Fellows earn a stipend for their service. Participants engage in outreach, build community relationships, and receive comprehensive training to enhance their legal skills, contributing to the resilience of affected communities.

Beckley Area Foundation

Beckley Area Foundation was established in January 1985 by ten community-minded citizens. It began with a gift of $1.1 million from the Dr. Thomas Walker Memorial Health Foundation as “seed” money for this Raleigh County project. BAF assets have grown to over $70 million with over 500 different funds managed by our three trustee banks. Today, Beckley Area Foundation is one of West Virginia’s largest community foundations.

Since its inception, BAF has distributed over $23 million to charities and other worthy projects in the fields of education, public recreation, health & human services, the arts, animal services and beautification.

Scholarships

The Beckley Area Foundation proudly manages scholarship funds established by individuals, businesses, and organizations dedicated to helping students pursue higher education. Many of these scholarships are tailored for specific schools, fields of study, or graduates from local high schools, while others offer broader opportunities. No matter the path, our scholarships aim to support students from our region as they work toward achieving their educational goals.

Most of these scholarships must be awarded to students from our geographic area or at least preference given to such students. While the majority of scholarships benefit Raleigh County applicants there are others designated for Fayette, Summers, Webster, and Wyoming students. 

Mary Louise Klaus Scholarship

A need and merit based scholarship; for Raleigh County, WV high school graduates continuing their education at any accredited vocational school, college or university.

This scholarship is renewable.

Scranton Area Community Foundation

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

Scholarships

We are honored to be the stewards of over 90 scholarship funds established by philanthropically-minded individuals in our community. Generous donors entrust us to connect them to dynamic students to provide financial resources for their education through scholarships. Our donors establish scholarship funds with criteria they wish to be met by applicants. Our scholarship committee considers the criteria, evaluates the submitted applications, and chooses the best candidates for each scholarship.

Stanley and Stella Becker Environmental Scholarship Fund

This scholarship is awarded to a graduating high school senior who is a resident of Monroe County and intends to pursue a degree in a field related to environmental science in a school of higher education.

Literary Arts Fund

Grants Overview

The Literary Arts Fund will award at least $50 million in grants to the nonprofit literary arts field over the next five years, concluding in 2031.

With a short timeline, the fund’s grantmaking has a strategic focus on the areas of the literary arts ecosystem where it determined it could have the greatest impact— that is: supporting independent U.S.-based literary arts nonprofits whose primary mission is directly serving adult writers of creative nonfiction, fiction, poetry, and hybrid works in making their artistic work and sharing it with readers outside of school and academic settings. Please review the fund’s full eligibility requirements to learn more.

Innovation project grants provide funding to literary arts nonprofits for projects that may be collaborative and that aim to address critical challenges in one or more literary arts nonprofit organizations, presses, or publications that, if improved, would directly benefit creative writers’ artistic work and ability to share it with readers and audiences. These grants are disbursed to nonprofits in a single payment and intended for use during the project period.

The Researcher Connection Program by Uplifting Athletes Inc. supports travel expenses for rare disease researchers and doctoral students, fostering connections within the rare disease community. It emphasizes health equity by reserving at least 20% of funding for underrepresented researchers. Qualified applicants can receive up to $1,450 for travel costs related to attending relevant conferences and events, enhancing collaboration and awareness in the rare disease field.

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

Jane Wynne Woolley Scholarship

Open to English Language Learners demonstrating financial need.

Award Amount:

• $1,000-$2,200   

The Petfinder Emergency Medical Grant assists Petfinder members in providing urgent medical care for pets in need. Grants range from $100 to $1,000 and are awarded monthly until funds are depleted. Eligible expenses cover various emergency treatments, with a focus on saving one pet's life or improving its quality of life. Applicants must be active Petfinder members and agree to share their stories on social media, promoting both the grant and the pets they help.

The NLN Nursing Education Scholarship Award offers up to $8,000 annually to support nurse educators pursuing advanced degrees. As the first organization dedicated to this cause, the NLN Foundation for Nursing Education aims to strengthen the nursing workforce in the U.S. and globally. Eligible candidates are NLN members and must be enrolled in accredited master's or doctoral programs, having completed at least one year of study. This initiative is vital for advancing nursing education and improving healthcare outcomes.

The HEAL Initiative: Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting rigorous pain research. This initiative promotes interdisciplinary partnerships and enhances the research environment for health professional trainees. Key deadlines include October 28, 2025, and October 27, 2026, for standard applications, and November 24, 2025, and November 23, 2026, for AIDS-related applications. Letters of Intent are encouraged 30 days prior to the due date.

The On My Way to Kindergarten Program offers essential resources to prepare children aged 3-5 for kindergarten. Developed with input from educators, it includes a bilingual activity book and online access to games, songs, and crafts in both Spanish and English. Funded by The Larry and Helen Hoag Foundation, this initiative aims to empower at-risk children and their families, ensuring they have the tools needed for a successful transition into school.

Community Foundation of New Jersey

Over our 46-year history, the Community Foundation of New Jersey has collaborated with individuals, families, organizations, and businesses to design charitable funds and implement the philanthropic solutions they want to see in their communities. We leverage $1.17 billion in assets and 1,200 funds to help our partners think boldly and creatively about ways to give.

Scholarship Fund Overview

Beyond a shared commitment to educational opportunity, families establish scholarship funds with a variety of goals and purposes in mind. They may offer traditional scholarships or customize fund awards for alternative scholarships.

Currently, CFNJ administers more than 135 scholarship funds. Our scholarship opportunities run the gamut, from those exclusive to a local high school or geographic region to those supporting specific majors or career pursuits. Last year, we awarded over $2 million in scholarship assistance to 271 scholars.

Applicants may be evaluated on academic performance; extracurricular activities; community involvement; paid or unpaid work; and a statement of their personal aspirations, educational goals, and demonstrated unmet financial need in our scholarship review process.

Blossom Scholarship

This scholarship is awarded to a college-bound, Black/African-American graduating high school senior from the greater Newark area or Paterson who has pursued a rigorous course of study (with particular emphasis on math and science courses). Applicants will show evidence of readiness for and a commitment to pursue a STEM major. Students will be evaluated on academic performance, extracurricular activities, community service, work (paid or unpaid), and unmet financial need.

Community Foundation of New Jersey

Over our 46-year history, the Community Foundation of New Jersey has collaborated with individuals, families, organizations, and businesses to design charitable funds and implement the philanthropic solutions they want to see in their communities. We leverage $1.17 billion in assets and 1,200 funds to help our partners think boldly and creatively about ways to give.

Scholarship Fund Overview

Beyond a shared commitment to educational opportunity, families establish scholarship funds with a variety of goals and purposes in mind. They may offer traditional scholarships or customize fund awards for alternative scholarships.

Currently, CFNJ administers more than 135 scholarship funds. Our scholarship opportunities run the gamut, from those exclusive to a local high school or geographic region to those supporting specific majors or career pursuits. Last year, we awarded over $2 million in scholarship assistance to 271 scholars.

Applicants may be evaluated on academic performance; extracurricular activities; community involvement; paid or unpaid work; and a statement of their personal aspirations, educational goals, and demonstrated unmet financial need in our scholarship review process.

Clanseer and Anna Johnson Scholarship

This scholarship is awarded to a college-bound, Black/African-American graduating high school senior from the greater Newark area or Paterson who has pursued a rigorous course of study (with particular emphasis on math and science courses). Applicants will show evidence of readiness for and a commitment to pursue a STEM major. Students will be evaluated on academic performance, extracurricular activities, community service, work (paid or unpaid), and unmet financial need.

The Bee Grant Program, offered by the Whole Kids Foundation, supports K-12 schools and non-profits in enhancing or establishing bee programs with live bees. The Traditional Bee Grant provides up to $1,500 or equipment for new initiatives, while the Renewal Bee Grant offers $500 to previously funded projects. Eligible applicants must ensure strong support from their organization and have a knowledgeable beekeeper as a mentor. This initiative emphasizes bee education and conservation, fostering awareness among students.

The Joe and Janet Barr Early Career Cornea and Contact Lens Research Award supports first- or second-year MS or PhD students in vision science or physiological optics. Established in 2012 in honor of Joseph T. Barr, this $2,000 seed funding facilitates research in cornea/ocular surface or contact lenses. Recipients are required to attend the annual American Academy of Optometry meeting and submit progress reports detailing their research outcomes. Preference is given to North American applicants.

The Washington Red Raspberry Commission offers research grants to support the advancement of red raspberry cultivation. These grants focus on innovative farming practices, pest management, and cultivar development, aimed at enhancing grower productivity and sustainability. Proposals are evaluated based on their potential impact on the industry, with an emphasis on practical applications. The commission invites researchers from various backgrounds to contribute, ensuring a diverse range of solutions for the challenges faced by raspberry growers.