Best Large Grants for Nonprofit Organizations in South Carolina

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship

The Rev. Clifford K. Cliver & Lucy Cliver Sumsky Scholarship Fund acknowledges and supports Chautauqua County foster children by providing scholarships for continuing education.

About

Community Foundation of Henderson County is a 501(c)(3) nonprofit, public charity, governed by a volunteer board of directors, that has been assisting donors fulfill their philanthropic dreams since 1982.

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Dan and Amy Pace Scholarship

This scholarship provides financial support to students who are graduates of a public high school in Henderson County and who plan to pursue a certification to teach high school English.

The Daily Bread Grants, offered by the Evangelical Lutheran Church in America, aim to support congregations with feeding ministries. Starting from November 1st, organizations can apply for $500 grants to help alleviate hunger in their communities. Priority is given to rural ministries, and applications will be accepted until funds are exhausted or until November 15th. This initiative not only provides immediate assistance but also encourages further financial support for food-based services.

EverGreen Dreams

“Empowering young Black women to achieve educational excellence and unlock their limitless potential.”

Today, EverGreen Dreams is a community rooted in hope, equity, and empowerment. Our work centers on providing the resources, mentorship, and opportunities Black women need to thrive. We believe education is more than a pathway to success—it’s a tool for liberation and a foundation for transformation. By investing in the education and development of Black women, we’re dismantling systemic barriers and planting seeds of possibility that will grow for generations.

Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship

Introduction

Black women navigate systemic barriers in education and the workplace every day. EverGreen Dreams exists to change that narrative. As an organization founded by a Black woman and championed by advocates deeply rooted in our communities, we're committed to creating pathways to success for the next generation of Black female scholars. Through the Building Opportunities for Sistas to Shine (B.O.S.S.) Scholarship, we provide financial support to two graduating high school seniors, awarding each at least $1,000 to help them pursue their educational dreams with one less obstacle in their way.

Description

The Building Opportunities for Sistas to Shine Scholarship (B.O.S.S.) aims to make racial equality a reality by helping outstanding Black cis or transgendered women high school students achieve their dreams to continue their education. 

The Beckman Scholars Program offers a 15-month mentored research experience for outstanding undergraduate students in chemistry and biological sciences. Each participating institution can submit one application, with awards totaling $21,000 per student and $5,000 per mentor. The program emphasizes justice, equity, diversity, and inclusion, welcoming applicants from diverse backgrounds. For more details, refer to the FAQs on the Arnold and Mabel Beckman Foundation's website.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Dunkirk Area Labor Council Scholarship

The Dunkirk Area Labor Council Scholarship supports graduating students who are furthering their education in the trades or manufacturing technology.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

David J Lewandowski Memorial Award

The David J Lewandowski Memorial Award is presented to a graduating senior from Dunkirk, Forestville, or Fredonia who is entering a career in the trades, agriculture, conservation, forestry, or emergency services.

The ASTR Teacher-Researchers Grant supports faculty with heavy teaching loads and limited research resources in theatre studies. This grant fosters scholarly exchange by providing an honorarium of up to $1000, complimentary conference registration, and a one-year ASTR membership. Applications are evaluated based on project feasibility and significance, with additional consideration for those facing institutional research support challenges. This initiative aims to enhance diversity and facilitate meaningful contributions to the field.

The Seymoure, Fred and Mildred (Young) Memorial Scholarship Fund offers a $500 scholarship to a Central Noble High School senior or graduate, or a resident of the Albion area pursuing a BS or MS in education. Established by the Noble County Community Foundation, this fund aims to support future educators in making a positive impact in their communities. Since 1991, the foundation has been dedicated to enhancing the quality of life in Noble County.

Community Foundation of the Ozarks

The Community Foundation of the Ozarks (CFO) provides philanthropic leadership to build stronger communities. Our mission is to enhance the quality of life in our region through resource development, community grantmaking, collaboration and public leadership.

We help donors achieve their philanthropic goals through professional management and investment of charitable funds. We work with nonprofit organizations to help them fulfill their missions through fund administration, grantmaking and learning opportunities. We award scholarships to deserving students to help them achieve their educational goals.

Clonts Anderson Scholarship

• Graduating high school senior from El Dorado Springs High School who is female
• GPA between 2.5 and 3.5; submit transcript
• Must be applying to a two-year or four-year accredited college, university or vocational school
• Demonstrate financial need; submit FAFSA-SAI form
• Describe participation in community service, school activities
• Essay required

About Association of Legal Writing Directors (ALWD) ALWD supports its members’ professional development as teachers, scholars, and leaders through both teaching and scholarship grants. These grants provide funding for legal writing professionals to pursue their scholarly interests and to develop innovative teaching materials. In funding grants, ALWD focuses on providing resources to those who do not have other sources of funding for these endeavors.

ALWD also supports projects that preserve the history of ALWD, honor community contributions, and make ALWD’s history accessible to scholars, teachers, and practitioners into the future.ALWD Teaching GrantsIn furtherance of ALWD’s commitment to the professional development of legal research and writing faculty, ALWD funds annual teaching grants that allow legal writing faculty to spend their summers exploring innovative teaching ideas and producing teaching tools, materials, and curriculum that will assist others in the field. 

The USS ST. LOUIS (LCS 19) Scholarship, established by the Commissioning Committee in 2020, supports crew members and their dependents pursuing undergraduate degrees or technical training. Administered by The Scholarship Foundation of St. Louis, it awards up to $12,000 annually, renewable for up to ten semesters. This initiative honors the commitment of the USS ST. LOUIS crew while fostering educational advancement and community engagement.

The ARS New Investigator Research Grant aims to support innovative research in rhinology, including basic, translational, and clinical projects. The funding period is non-renewable and lasts up to 24 months. Eligible candidates include American Rhinologic Society members who have completed residency and lack significant prior funding. The number of grants awarded is contingent upon the merit of applications received, as determined by the ARS Board of Directors. This grant provides a unique opportunity for emerging researchers in the field.

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Healthcare Excellence Scholarship Fund

The Aurora Integrated Oncology Foundation is pleased to offer scholarships to support Alaskan students achieve their fullest potential, with the goal of helping students improve their lives and improve healthcare in their communities.

The Chevron Changing the Face of Golf Scholarship, awarded by the LPGA Foundation, aims to empower female high school seniors from minority backgrounds pursuing STEM studies. Established in 2022, this scholarship promotes diversity in golf and education, honoring Dinah Shore's legacy. By supporting young women, the LPGA Foundation continues its mission to change the face of golf and provide educational opportunities, enhancing representation in both golf and STEM fields.

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Borislav Dumitrov Memorial Scholarship

Established by the family of Mr. Dumitrov to provide tuition assistance for a graduating senior from any of the High Schools in Susquehanna County who will matriculate at a trade school or post-secondary degree program.

The Bill and Joyce Coborn Memorial Scholarship supports Coborn's employees and their dependents pursuing private high school or post-secondary education. Offered by CommunityGiving, this scholarship provides up to 20 awards of $1,000 each, fostering educational advancement and community empowerment. Eligible applicants include high school seniors, college students, and graduate students who are children of Coborn's employees with at least one year of service. This initiative honors the legacy of Bill and Joyce Coborn while promoting lifelong learning.

The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.

Learning from Abroad to Reimagine Health Knowledge Systems for Equity and Wellbeing Grant

The Robert Wood Johnson Foundation (RWJF) is committed to dismantling structural racism and eliminating barriers to health equity by working alongside communities, practitioners, and institutions. One way we support this mission is by investing in the knowledge of historically marginalized communities and deepening the relationships that build community power, evidence, and systems of change. Another way we do this is by looking beyond the U.S. borders. The Global Ideas for U.S. Solutions team looks abroad for ideas to improve health equity, justice, and wellbeing in the U.S.  

This funding opportunity invites organizations to learn and produce solutions to build a more inclusive and equitable health knowledge system, inspired by other countries that have faced or are currently facing similar health equity challenges. It allows organizations to learn from efforts outside of the U.S. to reimagine and rebuild the health knowledge system in ways that can withstand systemic threats while advancing health equity and wellbeing for the future. Among many other characteristics yet to be identified, our learnings to date suggest that the following contribute to this reimagined version of the health knowledge system:  

• The experience of people most affected by health inequities is centered in the generation of data and evidence and in policymaking;
• Health is more than the absence of disease. It is about individual and collective healing and wellbeing;
• Mis- and disinformation are eliminated and public trust in science and evidence is restored;
• History, culture, and language are preserved and protected, and ecological and biomedical sciences are braided with Indigenous, traditional, holistic, and community frameworks; and
• Cross-sector approaches and global learning networks break down siloes and allow for more effective and equitable solutions. They leverage lessons from resistance movements and connect artists, researchers, public health, and civil society.

The purpose of this CFP is to support organizations in pursuing action-oriented projects that leverage learning from outside the U.S. to create a more durable and equitable health knowledge system in the U.S. These efforts will advance health equity, justice, and wellbeing through community-driven knowledge generation, preservation, and narrative. Together, these actions lay the foundation for a more inclusive, equitable, and resilient health knowledge system in times of crisis and beyond. 

Total Awards

Type of Award: Awards will be structured as grants and will be made to organizations, not to individuals.

• Number of Awards: Up to 15 awards will be funded.  
• Amount of Award: Awards will be up to $500,000 each. Please request only what is necessary to allow us to fund as many recipients as possible. We expect larger awards to correspond with more distributed funding (e.g., multiple people’s salaries or multiple activities). See more information on RWJF budget categories and allowable costs here.  
• Award Duration: Awards will be up to 36 months.  

Real World Evidence on clinical outcomes with Aztreonam-Avibactam (ATM-AVI)

This RFP invites research proposals aimed at assessing clinical outcomes associated with the use of Aztreonam-Avibactam (ATM-AVI) in real world clinical settings.

In scope are adult patients with suspected or documented infections due to aerobic gram negative organisms. Eg. CRE-MBL, Stenotrophomonas maltophilia, treated with ATM-AVI.

Geographic Scope

Countries where ATM-AVI is available (ex-US) and used in clinical practice at the time of RFP release, including but not limited to parts of EU, the United Kingdom, the Middle East, and selected Asia-Pacific markets. Proposals from institutions already participating in Pfizer-sponsored or funded, overlapping ATM-AVI RWE study may be considered out of scope. Proposals involving studies on patients that have received ATM-AVI via pre-approval or pre-launch expanded access routes may be considered out of scope

Project Types and Area of Interest

Potential applicants are requested to submit research proposals to study the below outcomes following treatment with ATM-AVI for adult patients with suspected or documented infections with aerobic gram negative organisms e.g. CRE-MBL, S. maltophilia.

• Clinical effectiveness with ATM-AVI
• Safety outcomes with ATM-AVI
• Microbiological outcomes with ATM-AVI
• Health Economic outcomes with ATM-AVI (in addition to any of the above)

Proposals may include data from special populations such as – immunocompromised (solid organ transplant or haemato-oncological patients)

Funding Range and Project Length

• Individual projects requesting up to $50,000 USD will be considered. The total budget for this RFP is $ 250,000 USD
• Maximum project length is 12 months

Community Foundation of the Endless Mountains

Our mission at the Community Foundation of the Endless Mountains is to improve the region’s quality of life through the power of philanthropy. We do this by offering individuals, families, and businesses the most effective charitable giving tools available in the marketplace today. Founded in 1998, the Community Foundation of the Endless Mountains is honored to work with hundreds of donors, nonprofits, advisors, and civic leaders to achieve dreams for making the Endless Mountains region of Northeastern Pennsylvania an even better place to live for everyone.

Scholarships

Many generous individuals, families, and businesses have established scholarship funds to provide support to graduates in our region. Scholarships are available to graduating high school seniors.

Thomas Conaty Memorial Scholarship

Established by the family of Mr. Conaty to provide a college or post-secondary degree program scholarship to a student from Blue Ridge, Elk Lake or Montrose Area School Districts, including home schooled students from those districts. Preference will be given to a student who will pursue a degree in business or a related field.

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Greater Ketchikan Chamber of Commerce Endowed Scholarship Fund

The mission of the Greater Ketchikan Chamber of Commerce is to advocate and educate on behalf of members to promote a healthy business climate that recognizes both Ketchikan’s quality of life and its economic potential.

Our vision for Ketchikan is a community with a strong and diversified economy, a year-round, stable employment base, and a quality of life which is both attractive to prospective residents and conducive to business expansion and sustainable new development.

For more information about the Greater Ketchikan Chamber of Commerce, please visit their website at https://www.ketchikanchamber.com/

The ASTR Theater and Performance Art Studies Research Fellowships provide funding for scholars conducting significant research in theatre and performance studies. With awards up to $3000, these fellowships support academic projects, allowing recipients to cover various research expenses. Eligible applicants include anyone holding a terminal degree and a member of ASTR, with the selection based on project merit. However, applicants cannot seek a Targeted Research Area Grant for the same project in the same year.

The Scholarships for Careers Endowment, established by a local family in connection with the Community Foundation of the Endless Mountains, aims to support graduates of Elk Lake School District and the Susquehanna County Career & Technology Center. This scholarship prioritizes students with financial need and promise for future success, assisting them in pursuing vocational, technical, academic, or other post-secondary programs. Additionally, it contributes to special projects within the school district and community.

The Pompe Disease Fund, supported by the Patient Advocate Foundation, offers vital financial assistance to individuals diagnosed with Pompe disease. This fund covers out-of-pocket healthcare costs including medication copays and health insurance premiums. Eligible patients must have a confirmed diagnosis and be receiving treatment or planning to start within 60 days. With over 3.8 million patients helped since its inception, the fund aims to alleviate financial burdens and enhance access to necessary treatments.

The Bee Grant Program, offered by the Whole Kids Foundation, supports K-12 schools and non-profits in enhancing or establishing bee programs with live bees. The Traditional Bee Grant provides up to $1,500 or equipment for new initiatives, while the Renewal Bee Grant offers $500 to previously funded projects. Eligible applicants must ensure strong support from their organization and have a knowledgeable beekeeper as a mentor. This initiative emphasizes bee education and conservation, fostering awareness among students.

The Bernick Family Foundation Scholarship, provided by CommunityGiving, aims to support high school seniors in their pursuit of higher education. This scholarship recognizes well-rounded students from the Bernick Service Area who maintain a GPA of 3.0 or better. With 10 scholarships available, each worth $2,000, the foundation seeks to inspire philanthropy and empower local communities through education. Applications are accepted online, and candidates must have or create a Scholarship Management System account to apply.