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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

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$2.62B

Total funding

$5K

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9,000+ grants
$2.62B total
$5K median

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Frankenthaler Climate Initiative: Technical Assistance Grant

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $50,000

Helen Frankenthaler Foundation

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Frankenthaler Climate Initiative

The Frankenthaler Climate Initiative (FCI) is a pioneering grantmaking program established by the Helen Frankenthaler Foundation. Since its inception in 2021, FCI has distinguished itself as the foremost private national initiative in the United States dedicated to combating climate change specifically within the visual arts sector.

FCI provides visual arts institutions with up to $100,000 to undertake ambitious sustainability and energy efficiency initiatives that directly address carbon reduction and energy efficiency. The scope of its support is broad, encompassing everything from modest, rapid-response projects to comprehensive efficiency audits and feasibility studies, and extending to financial contributions for significant infrastructural renovations and strategic planning for new buildings and major initiatives.

Building on the core values of the Helen Frankenthaler Foundation, the initiative aligns a commitment to environmental stewardship with a belief in the vital importance of the visual arts and arts education. Through strategic funding and partnerships focused on tangible infrastructure, FCI aims to catalyze a sector-wide shift toward zero carbon operations, promoting a future where the visual arts thrive—while contributing to a more sustainable and ecologically conscious world.

Who We Fund

FCI funds nonprofit institutions in the United States and its territories whose primary focus rests in the visual arts. The visual arts includes but is not limited to painting, drawing, sculpture, printmaking, photography, and installations in clay, glass, metal, wood, fiber, paper, film, and mixed media.

Most of our grantees are art museums, nonprofit galleries, archives, noncollecting institutions, art schools, university museums, and artist-endowed foundations.

What We Fund

FCI funds energy efficiency and clean energy generation projects.

FCI meets arts institutions at every stage of the work, through four kinds of grants:

  • Catalyst — first actions and stand-alone projects with a quick turnaround
  • Scoping — energy audits and assessments that establish a baseline
  • Technical Assistance — detailed planning for technically demanding projects
  • Implementation — comprehensive capital work addressing a building's environmental impact at multiple levels

Technical Assistance Grants

Technical Assistance grants support projects that have finished initial assessments, and need procurement and financing support for an identified efficiency project. This may include providing designs, specifications, or fees for working with energy services companies (ESCOs) for project support. These grants also support more complex studies or analysis required for pursuing major implementation projects. At the conclusion of a Technical Assistance grant, the applicant should be sufficiently informed to implement a project.

Energy Efficiency & Conservation Visual Arts Film +3 more

Richard S. Reynolds Foundation Grant

Richard S. Reynolds Foundation
Private
United States
Unspecified amount
The Richard S. Reynolds Foundation, established in 1955 in Richmond, Virginia, supports diverse community initiatives in education, healthcare, the arts, and the environment. With over $71 million granted to date, it aims to strengthen communities and foster future generations. The foundation prioritizes requests from IRS-recognized 501(c)(3) organizations while typically avoiding contributions to annual operational costs. Its commitment to impactful projects ensures a lasting positive influence both locally and globally.
Education Art & Culture Science +6 more

Hunger to Health Collaboratory (H2HC) 2026 Prizes for Innovation

Newmans Own Foundation
Corporate
United States
Up to US $100,000
The Hunger to Health Collaboratory (H2HC) 2025 Prizes for Innovation aim to enhance health equity for youth through innovative funding in three categories: Food and Nutrition Policy, Nutrition Education & School Food, and Indigenous Food Justice. Supported by Newman’s Own Foundation, these prizes include $100K grants for policy work and $25K grants for education and justice initiatives. Winners will participate in the H2HC Fall Summit in Boston, fostering collaborative solutions to food challenges.
Food Access & Hunger Youth Services Indigenous Sovereignty & Rights +2 more

Aspiring Educators CREATE Grants

National Education Association Staff Organization
Private
United States
Up to US $2,000
The Aspiring Educators CREATE Grants, funded by the National Education Association Staff Organization, offer up to $2000 to strengthen the AE Program and foster impactful partnerships. Grants focus on areas such as Educator Quality, Community Engagement, Political Action, and Social Justice. Eligible organizations include state AE chapters, and submissions are accepted three times a year. This initiative encourages aspiring educators to develop their skills and contribute meaningfully to their communities.
Social Justice / Human Rights Education - K through 12 Educational Access & Equity +3 more

Taos Diplomats Scholarship

The Taos Community Foundation Inc
Private
United States
US $250 - US $1,000

Taos Diplomats Scholarship

The Taos Diplomats Scholarship was first established in 2015 by Peter Winter (Taos High ’04) and Dori Winter, who have served as Foreign Service Officers with the U.S. Department of State. During college at the University of Southern California, Peter studied International Relations and Mandarin Chinese, later studying abroad in Beijing, China. Dori, a graduate of the University of South Carolina and Texas A&M University, studied in China and France. Both have represented the United States government at embassies and consulates around the world, including assignments in Northern Ireland, Egypt, Pakistan, China, Israel, and Saudi Arabia.

This award is open to graduating High School Seniors from Taos County (GPA of 3.0 or above) who are interested in pursuing a degree in fields such as international affairs, political science, public and government policy, global communications, international education and development, global health, international business, and foreign languages or studying abroad. This scholarship is open to those applying to 4 year colleges and universities as well as 2 year vocational/trade schools. The award ranges from $250.00 to $1,000.00 and is paid directly to the student’s account at the college or university attended.

Education - Higher Education Vocational & Trade Education Political Science +4 more

Ann Wall Scholarship

Scranton Area Foundation Inc
Private
United States
Unspecified amount

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a student matriculating at a college, university, or business in the year of the scholarship.

Education - Higher Education Business Education Disability Care & Services +3 more

CAPTRUST Crisis Grants

CAPTRUST Community Foundation Inc
Private
United States
Unspecified amount
The CAPTRUST Community Foundation provides Crisis Grants to support nonprofit organizations aiding families impacted by natural disasters or emergencies. By dedicating over 10% of its annual budget for crisis assistance, the foundation ensures that funds directly benefit those in need. Grants can be requested up to $5,000 to help rebuild lives during challenging times, reflecting the foundation's commitment to integrity and support for children and families in crisis.
Family Services Disaster Relief / Humanitarian Aid Crisis Intervention +1 more

ALA Spectrum - Scholarship Program

American Library Association (ALA)
Association/Society
United States
US $5,000
The ALA Spectrum Scholarship Program offers a one-time $5,000 scholarship to support diverse students pursuing graduate education in library and information studies. Recipients must enroll in an accredited program by fall, receiving funds in two installments. This initiative, supported by the American Library Association, enhances opportunities for over 800 past scholars through mentoring, networking, and professional development, fostering leadership within the library profession across North America.
Library & Information Science Asian / Pacific Island Culture & Heritage Native American Culture & Heritage +3 more

Community Traffic Safety Grants

National Safety Council
Private
United States
US $50,000 - US $200,000
The Community Traffic Safety Grants, initiated by the Road to Zero Coalition, aim to eliminate traffic fatalities by 2050 through innovative, evidence-based approaches. The program invites proposals from Road to Zero Coalition members, particularly non-profits and government entities, to implement effective countermeasures that enhance traffic safety and address mobility disparities. Projects should be replicable and scalable, demonstrating measurable outcomes and contributing to a positive safety culture on U.S. roads.
Community / Public Safety Pedestrian & Bike-Friendly Infrastructure Public Infrastructure

Firehouse Subs Public Safety Foundation Scholarship Program

Firehouse Subs Public Safety Foundation
Corporate
United States
US $5,000
The Firehouse Subs Public Safety Foundation Scholarship Program supports students aiming to enroll in firefighter, law enforcement, or emergency medical programs at accredited institutions. Established in 2005, the foundation provides $5,000 scholarships to eligible candidates, including high school seniors and current college students. The program emphasizes commitment to public safety and community service, assisting those pursuing careers as first responders. This initiative highlights the foundation's dedication to enhancing lifesaving capabilities within local communities.
Education - Higher Education Firefighting & Fire Prevention Police & Law Enforcement +2 more

OneRural Direct Technical Assistance Services Grant

Housing Assistance Council
Private
Puerto Rico, United States
Unspecified amount
OneRural provides essential technical assistance to rural organizations, fostering the development of affordable housing and community initiatives. This program offers tailored support, helping organizations enhance their operational capabilities and drive impactful change. By accessing expert resources and training, participants can effectively navigate challenges, improve program outcomes, and strengthen community resilience. This initiative targets nonprofits and tribal entities, ensuring that rural communities receive the guidance needed for sustainable growth and development.
Community Development & Revitalization Rural Development Equitable & Affordable Housing

Artistic Production Grant Program

VIA Art Fund
Private
American Samoa, Guam +4 more
US $25,000 - US $100,000
The VIA Art Fund provides Artistic Production Grants to support innovative artistic commissions for public spaces. These grants, ranging from $25,000 to $100,000, are awarded twice a year to artists and organizations that exemplify artistic excellence and public engagement. Projects must have a confirmed exhibition venue, ensuring artworks reach diverse audiences and foster meaningful community experiences beyond traditional gallery settings.
Arts / Culture Access & Participation Public / Community Art Art & Culture +3 more

Laura Bush 21st Century Librarian Program (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
American Samoa, Guam +7 more
US $25,000 - US $1,000,000
The Laura Bush 21st Century Librarian Program aims to enhance the library and archival workforce by addressing community information needs and strengthening institutional capacities. It supports innovative projects that explore alternative pathways into library services, advance continuing education, and foster recruitment and retention of future professionals. By focusing on diverse training and development, the program seeks to cultivate a new generation of library leaders equipped to meet evolving challenges.
Education - Higher Education Library & Information Science Workforce Preparation & Job Readiness +1 more

Yawkey Foundation: Transformational Capital Grant

Yawkey Foundation
Private
Barnstable County, Massachusetts, Bristol County, Massachusetts +6 more
Up to US $5,000,000
The Yawkey Foundation's Transformational Capital Grant provides significant funding, up to $5 million, for nonprofit organizations to enhance their mission delivery through the development of impactful physical spaces. The grants are highly competitive and require compelling proposals demonstrating project need, community support, and financial commitment. Organizations must align with the Foundation's priority Areas of Giving, primarily serving Eastern Massachusetts and Georgetown County, South Carolina. Review timeframe for proposals is approximately 12-18 months.
Health Care Access & Delivery Education Human & Social Services +4 more

CHEERS Open Period 1 - All Technical Areas

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
United States
Unspecified amount
The CHEERS Open Period 1 invites white papers focused on enhancing operational medicine and support for Airmen and Guardians. Managed by the Air Force Research Laboratory and USAFSAM, this opportunity aims to address future demands in Aerospace Medicine, Occupational Health, and Public Health. Proposals should align with the objectives outlined in the Continuing Human Enabling, Enhancing, Restoring and Sustaining announcement. This initiative emphasizes innovative solutions to support the Department of Defense's mission.
Health & Medicine Human Physiology Epidemiology & Public Health +3 more

Northern Lowcountry Grants: Open Grants

Coastal Community Foundation of South Carolina
Private
Berkeley County, South Carolina, Charleston County, South Carolina +2 more
Up to US $15,000
The Northern Lowcountry Grants, offered by the Coastal Community Foundation, support nonprofits in Berkeley, Charleston, Dorchester, and Georgetown counties. Grants up to $15,000 are available for projects focusing on arts, hospice care, and Alzheimer's-related disorders. For other initiatives, applicants may request up to $10,000. Established in 1974, the foundation aims to enhance community vibrancy by addressing regional challenges and promoting resource collaboration.
Art & Culture Dementia & Alzheimer’s Disease Hospice / End of Life Care

Workforce Development Scholarship

Agc Education And Research Foundation
Private
United States
US $1,000

AGC Education and Research Foundation

Thanks to visionary volunteer leadership of AGC industry leaders, the AGC Education and Research Foundation, founded in 1968, has for 50 years made good on its commitment to support the future of our industry through its robust scholarship program and innovative projects.

Workforce Development Scholarship

In 2015, the National Center for Construction Education and Research (NCCER) and its Build Your Future initiative made a generous contribution to help fund the first Workforce Development scholarships for students pursuing craft and technical programs, allowing 19 applicants to receive the inaugural scholarships. Scholarships are $1,000 per year, renewable for up to two years.

This is the application for the Workforce Development Scholarship. This scholarship is for students pursuing associate degrees, technical training or certificates to enter the construction industry. Please review the Criteria Page to ensure you qualify for the Workforce Development Scholarship. Scholarships are $1,000 per year, renewable for up to two years. If you are attending a four year university and intend to earn a Bachelor's degree please make sure to apply for our Undergraduate Scholarship application.

Education - Higher Education Civil Engineering Academic Scholarship Programs +1 more

The Prof. Rahamimoff Travel Grants for Young Scientists

United States-Israel Binational Science Foundation
Federal Government
Israel, United States
US $6,000
The Prof. Rahamimoff Travel Grants for Young Scientists support PhD students in research requiring expertise unavailable in their home countries. Named after renowned scientist Prof. Rami Rahamimoff, the grants fund trips to higher education or research facilities in the U.S. or Israel, lasting up to two months. Eligible applicants must be U.S. or Israeli citizens conducting supervised research at accredited institutions. This program honors Prof. Rahamimoff's legacy in science and medicine.
Economics Energy Engineering +9 more

Aes Hawaii Foundation Grant

AES HAWAII FOUNDATION
Private
United States
Unspecified amount
The AES Hawaiʻi Foundation Grant supports communities near AES Hawaiʻi’s renewable energy projects, focusing on social justice, education, environmental stewardship, and community health. Preference is given to nonprofit organizations in these areas, but statewide entities may also apply. Successful projects should align with the Foundation’s impact pillars, demonstrate measurable community benefits, and address unmet needs, ensuring long-term positive effects on the local community.
Social Justice / Human Rights Workforce Preparation & Job Readiness Community Health Education +2 more

Health Careers Scholarship of Sonoma County

10000 DEGREES
Private
United States
Unspecified amount
The Health Careers Scholarship of Sonoma County, administered by 10,000 Degrees, supports students pursuing careers in medicine, nursing, or allied health fields. Established in 2001, it is open to undergraduate and graduate students who are residents of Sonoma County or graduated from its high schools. Applicants must demonstrate academic excellence with a minimum 3.0 GPA and provide two letters of recommendation, excluding relatives. This scholarship is a vital resource for aspiring healthcare professionals in the community.
Health & Medicine Nursing Academic Scholarship Programs +3 more

Impact Fund Grants

The Impact Fund
Private
United States
US $10,000 - US $50,000
The Impact Fund provides recoverable grants to legal services nonprofits and small law firms working on social, environmental, and economic justice issues. With over $10 million awarded since 1992, the fund supports impactful litigation addressing systemic injustices. Grants range from $10,000 to $50,000 and prioritize cases directly involving affected communities. Recipients must repay the grant amount with interest if they recover fees or costs, ensuring sustainability for future funding.
Social Justice / Human Rights Environmental Justice & Advocacy Economic Rights, Justice, & Mobility +1 more

OneAmerica Financial: Community grant

OneAmerica Financial
Corporate
United States
Unspecified amount
The OneAmerica Financial Community grant supports 501(c)(3) organizations focused on education, workforce development, safety, wellness, and community vibrancy. With a commitment to making a difference, OneAmerica aims to transform lives through strategic philanthropy. Their initiatives include disaster relief, arts support, and civic engagement, fostering resilient communities. By investing in meaningful change, they build a foundation for shared success across the country, ensuring that community needs are met and future generations thrive.
Basic Human Needs Education - K through 12 Workforce Preparation & Job Readiness +1 more

J.B. Hunt Transport Services: Company Giving

J.B. Hunt Transport Services
Corporate
United States
Unspecified amount
J.B. Hunt Transport Services offers financial support for various community projects through its Company Giving program. Focused on four key areas—Health Care, Veterans' Support, Education, and Crisis Management—this initiative aims to enhance the well-being of local communities. Eligible applicants include 501(c)(3) organizations, schools, and civic groups, while organizations that primarily benefit their members or have high management overhead may be excluded. The program underscores J.B. Hunt's commitment to corporate social responsibility.
Health Care Access & Delivery Military & Veterans Services Education +1 more

Connected Futures Cohort Grant

New Profit Inc
Private
United States
US $110,000

About Us

We are a philanthropic organization committed to catalyzing the impact of social entrepreneurs who are expanding access and opportunity in America. 

At New Profit, we partner with social innovators, philanthropists, and other impact leaders who are creating a more inclusive and prosperous America. We invest in and support leaders and organizations that are transforming our education, economic, and democratic systems. And we are guided by the belief that those who are most proximate to the communities we serve are the best positioned to develop effective and sustainable solutions.

We seek and support leaders and organizations with scalable solutions that match the size of the problems we face and expansive visions that match the scale of our ambitions for America.

Connected Futures Cohort Grant

New Profit is launching Connected Futures, a Catalyze cohort for organizations that bridge divides and bring people together to solve problems collectively. Submit a Discovery Form to signal your interest and to be considered to submit an application for this funding cycle. 

New Profit’s Catalyze cohorts support innovative social impact organizations expanding access and opportunity in America. This model brings together cohorts of organizations with similar focus areas and stages, providing each with a one-year $100,000 unrestricted grant, a $10,000 grant for leadership development, and strategic advisory support.

Social Entrepreneurs* participate in a year-long cohort experience designed to build community, facilitate peer learning, and provide capacity-building support, including workshops on topics such as board development, fundraising, scenario planning, and storytelling. 

About Connected Futures

Connected Futures is a new Catalyze cohort for organizations that help people move across active divides to take action toward common goals. We are looking for organizations that build trust, strengthen collaboration, and create ways for people to act together when mistrust, polarization, exclusion, or disconnection would otherwise keep them apart and prevent them from solving problems together.

These organizations may work in the health, economic mobility, democracy, and/or education sectors. What connects them is not a single issue area, but a common approach to bridgebuilding: creating the relationships, skills, and structures people need to work together toward positive change.

Catalyze cohorts are at their best when cohort members are fully engaged. The Social Entrepreneurs that lead selected organizations are expected to participate in the Catalyze support model and peer learning community in the following ways:

  • Social Entrepreneurs attend three in-person convenings, each of which are held over 3-4 days in cities across the United States. Convening dates for this cohort will be shared with organizations invited to complete a full application.
  • Social Entrepreneurs attend three virtual learning sessions, each lasting 2-3 hours. Webinar dates for this cohort will be shared with organizations invited to complete a full application.
  • Social Entrepreneurs engage with the New Profit team via 1:1 strategic advising, including a minimum of six virtual sessions over the yearlong cohort.
  • Entrepreneurs receive a $10,000 stipend specifically to support their own leadership development goals.
  • Programming requires a commitment of 6-8 hours per month on average. New Profit covers the cost of travel, accommodation, and meal expenses for each in-person convening.

Economic Services & Development Entrepreneurship Business Development +2 more

Ruth Abernathy Presidential Scholarship: Graduate

Society Of Health And Physical Educators
Private
United States
US $1,750
The Ruth Abernathy Presidential Scholarship, established by SHAPE America, honors outstanding graduate students in health and physical education. Awarded annually since 1995, it recognizes two graduate recipients based on academic excellence and leadership. Along with financial support, winners receive a three-year SHAPE America membership, enhancing their professional network. This scholarship underscores the organization's commitment to advancing health education and supporting future leaders in the field.
Education - Higher Education Recreation Dance +2 more

Ruth Abernathy Presidential Scholarship: Undergraduate

Society Of Health And Physical Educators
Private
United States
US $1,250
The Ruth Abernathy Presidential Scholarship is awarded annually by SHAPE America to honor outstanding undergraduate and graduate students in health and physical education. Established in 1995, this scholarship supports three undergraduate and two graduate recipients. Candidates must be SHAPE America members, majoring in relevant fields, and demonstrate academic excellence and leadership. In addition to financial support, recipients receive a three-year membership to SHAPE America, fostering a commitment to health education and physical activity.
Recreation Dance Wellness & Healthy Living +2 more

Honda’s Community Event Sponsorship

Honda USA Foundation
Private
Alamance County, North Carolina, Allen County, Ohio +48 more
Up to US $25,000
Honda’s Community Event Sponsorship aims to support local, regional, and national events that enhance community engagement and celebrate diverse cultures. Organizations must be U.S.-based and tax-exempt, focusing on projects that serve communities where Honda associates are active. Eligible events include parades, festivals, and educational initiatives. Honda evaluates requests based on community needs and available funding, reinforcing its commitment to social responsibility and community enhancement.
Community Culture & Heritage Recreation Music Festivals +1 more

Large Grants for Nonprofit Organizations in South Carolina Highlights

Looking for large grants for nonprofit organizations in South Carolina?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

40 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081