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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

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9,315 Results based on applied filters

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) (352163)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Natural Product Early Phase Clinical Trial Award (R33) invites applications for early phase clinical trials of natural products like botanicals and dietary supplements. This funding aims to support studies that assess the impact of these products on target engagement and clinical outcomes. The NOFO encourages innovative designs that optimize delivery methods and investigate combinations with existing treatments. With a maximum support period of three years, the initiative seeks to translate basic science findings into practical clinical applications.
Integrative & Alternative Health Drug Safety Food Safety

Multiple Sclerosis Clinical Care Physician Fellowship: Adult Care

National Multiple Sclerosis Society
Association/Society
United States
US $75,000
The Multiple Sclerosis Clinical Care Physician Fellowship is a one-year program by the National Multiple Sclerosis Society aimed at training neurologists and physiatrists in specialized clinical care for MS patients. Eligible candidates include PGY3 or PGY4 residents from U.S. programs. The fellowship focuses on supervised patient care, multidisciplinary team activities, and professional development, preparing fellows to provide high-quality care and to engage as future leaders in the MS community.
Medical Education & Professional Training Multiple Sclerosis

Apraxia Kids Childhood Apraxia of Speech (CAS) Clinical Research Grant

Childhood Apraxia of Speech Association of North America
Association/Society
United States
Up to US $40,000
The Apraxia Kids Childhood Apraxia of Speech (CAS) Clinical Research Grant focuses on funding high-quality research applicable to childhood apraxia of speech. With an award of up to $50,000, it supports studies addressing early diagnosis, treatment approaches, and the impact of CAS on literacy and phonological skills. Apraxia Kids encourages proposals that consider diverse populations and comorbid conditions, aiming to enhance understanding and outcomes for children with CAS.
Children’s Health & Pediatrics Speech-Language Learning & Disorders

Elsie Beavers Carver and E. Lois Carver Educational Fund Grant

Waccamaw Community Foundation
Private
Georgetown County, South Carolina, Horry County, South Carolina
Up to US $2,500
The Elsie Beavers Carver and E. Lois Carver Educational Fund Grant supports K-12 educational programs in Horry and Georgetown Counties. It aims to enhance children's learning experiences in core subjects such as language arts, math, and the arts. Eligible applicants must be 501(c)(3) nonprofit organizations. The fund provides resources for equipment, supplies, and special projects, ensuring that no qualified individual is excluded from participation based on various factors.
Education - K through 12 Art Education STEM / STEAM Education +1 more

Gable Grants Program

Lowe's Foundation
Private
United States
US $100,000 - US $1,000,000
The Lowe's Foundation Gable Grants Program aims to address the skilled trades labor shortage by investing $50 million over five years to train 50,000 job-ready workers. The program supports community and technical colleges, as well as community-based nonprofit organizations, to enhance their skilled trades education initiatives. Eligible organizations can apply for grants from March 1, 2025, to October 1, 2025, to foster workforce development in essential trades such as HVAC, plumbing, and construction.
Workforce Preparation & Job Readiness Vocational & Trade Education

OJJDP FY 2026 Juvenile Drug Treatment Court Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.
Mental Health & Psychiatric Diseases Youth Services Crime & Justice +1 more

RSF: Future of Work Grant Program

Russell Sage Foundation
Private
United States
Up to US $75,000
The Russell Sage Foundation's Future of Work Grant Program seeks innovative research proposals that explore the impact of job quality changes on low- and moderately paid workers in the U.S. The program emphasizes studies on employer practices, labor market dynamics, and public policies. It prioritizes projects utilizing new data or unique methods, focusing on issues like job automation, labor market shifts post-COVID-19, and the effects of emerging technologies on workforce wellbeing.
Workforce Preparation & Job Readiness Workers’ Rights

SBE Postdoctoral Research Fellowships

National Science Foundation (NSF)
Federal Government
United States
Up to US $160,000
The SBE Postdoctoral Research Fellowships, offered by the National Science Foundation (NSF), are designed to promote early-career independence by supporting research and training goals in the social, behavioral, and economic sciences. Applicants can choose between two tracks: Fundamental Research and Broadening Participation. This initiative addresses significant scientific questions, aligning with NSF's mission to enhance the scientific workforce and foster diversity in research fields.
Linguistics Anthropology & Cultural Studies Geography +5 more

Lincoln Financial Scholars Program

United Negro College Fund Inc
Private
United States
Up to US $3,000

Who We Are

Our Mission

UNCF envisions a nation where all Americans have equal access to a college education that prepares them for rich intellectual lives, competitive and fulfilling careers, engaged citizenship and service to our nation.

UNCF’s mission is to build a robust and nationally-recognized pipeline of under-represented students who, because of UNCF support, become highly-qualified college graduates and to ensure that our network of member institutions is a respected model of best practice in moving students to and through college.

2026-2027 Lincoln Financial Scholars Program

The Lincoln Financial Scholars program provides college students with professional development and scholarship assistance to help prepare them for internships and early career opportunities

The Experience

Through engagement in live webinars and online learning management system, scholars will receive training in the following key areas to prepare for internship opportunities and early career opportunities

  • Exploring the True Colors Personality Lens 
  • Exploring Transferable Skills: Emotional Intelligence 
  • Cultivation of Professional Skills: Networking - Branding - Managing Up 
  • Financial Wellness

Each eligible student will be awarded a one-time, scholarship award of up to $3,000.

Career / College Preparation Apprenticeship & Internship Programs Black American Services

NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required) (352165)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites applications for early phase clinical trials focused on natural products. This funding opportunity supports research into botanicals and dietary supplements that show promise based on preliminary evidence. Successful trials can receive up to six years of funding to enhance understanding of pharmacokinetics and clinical impacts. Applications must aim to optimize product delivery and explore innovative combinations with other treatment approaches.
Food Safety Drug Safety Integrative & Alternative Health

National Scleroderma Foundation: Pediatric Scleroderma

National Scleroderma Foundation
Private
United States
Up to US $500,000
The National Scleroderma Foundation supports pediatric scleroderma research with up to $500,000 in funding for new and established investigators. Their mission focuses on advancing medical research and promoting awareness of scleroderma, with the vision of improving the lives of those affected. This initiative aims to encourage innovative research that could lead to better treatments and a potential cure for pediatric scleroderma, enhancing support for affected families.
Rare Diseases Immune System Diseases Children’s Health & Pediatrics

Palumbo Charitable Trust Grants

A.J. and Sigismunda Palumbo Charitable Trust
Private
United States
Unspecified amount
The A.J. and Sigismunda Palumbo Charitable Trust supports organizations committed to enhancing the lives of children and young adults. They focus on educational institutions, health-related initiatives, and community services in the St. Marys, Pennsylvania area. Grants are awarded to 501(c)(3) organizations demonstrating accountability and measurable outcomes, with a preference for projects that benefit the community at large. The Trust encourages collaborative funding efforts and endeavors that inspire hope and vision.
Youth Services Community Services Catholicism +2 more

Richard J. & Irma E. Larson Scholarship Endowment Fund

Community Foundation of the Fox River Valley
Private
United States
US $1,000

Community Foundation of the Fox River Valley

The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.

We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.

Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.

The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.

Richard J. & Irma E. Larson Scholarship Endowment Fund

The Richard J. and Irma E. Larson Scholarship Endowment Fund was established to help Aurora area high school graduates attend colleges and universities to further their education in the fields of law, teaching, Christian ministry and agriculture.

Richard, better known as Dick, and Irma are both graduates of Wartburg College in Waverly, Iowa. Dick received his Juris Doctor Degree from the University of Illinois College of Law. Irma earned her Master’s Degree from Northern Illinois University.

Irma has served on several community boards, including Child Welfare, the Aurora YWCA, P.E.O. Chapter DD, and The Mid-West Early American Pressed Glass Club. After retirement, she volunteered as a Court Appointed Special Advocate (CASA) for nine years.

The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.

Law Education Education - Higher Education +2 more

Virginia Urology Center Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $2,000

The Community Foundation for a Greater Richmond

The Community Foundation of Richmond is a philanthropic organization dedicated to improving quality of life across the Richmond region by connecting people, ideas, and resources for lasting community impact. The Foundation manages charitable funds, supports local nonprofits, and leads strategic initiatives that address community priorities such as education, health, economic opportunity, and equity. Through grantmaking, donor services, and community leadership, the Foundation works to strengthen nonprofits, respond to emerging needs, and build a more resilient, inclusive, and thriving Richmond-area community.

Virginia Urology Center Scholarship

The Virginia Urology Center Scholarship Program was established in 1999 to benefit graduating seniors from public and private high schools in communities where Virginia Urology offices are located, including Metropolitan Richmond, the Tri-Cities, Northern Neck, Middle Peninsula and South Hill. The scholarship supports post-secondary study in the fields of science and medicine. Funds awarded will help to cover the costs of tuition, room, board, books and laboratory fees.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.
Health & Medicine Atmospheric Sciences Climatology +2 more

W. J. Blanchet Scholarship

The Community Foundation for a Greater Richmond
Private
United States
US $2,000
The W. J. Blanchet Scholarship, offered by The Community Foundation for a Greater Richmond, supports graduating high school seniors from Northumberland County who demonstrate financial need and a commitment to academic excellence and community service. Preference is given to members of local churches. This scholarship aims to empower students to pursue higher education at accredited institutions, fostering educational growth and community engagement in the region.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Transport Phenomena (TP)

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Transport Phenomena (TP) program, supported by the National Science Foundation, aims to advance fundamental research in the transport of mass, momentum, energy, and species across various scales. This initiative focuses on innovative methodologies that enhance our understanding of single- and multiphase systems, thermodynamic processes, and combustion dynamics. By integrating theoretical, experimental, and computational approaches, TP seeks to connect microscale phenomena with broader engineering applications, ultimately contributing to national priorities in energy, biotechnology, and environmental sustainability.
Engineering Bioengineering Chemical Engineering +5 more

Staab Construction Scholarship

Marshfield Area Community Foundation Inc.
Private
United States
Unspecified amount

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Staab Construction Scholarship (2025)

Education - Higher Education Educational Access & Equity Engineering +2 more

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI) (363905)

US DOD: U.S. Army Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.
Engineering Science Workforce Preparation & Job Readiness +1 more

Sony: Corporate Giving

Sony Corporation of America
Corporate
United States
Unspecified amount
Sony Corporation of America focuses its charitable giving on arts, culture, technology, and the environment, with a strong emphasis on education in these fields. It supports registered 501(c)(3) non-profit organizations while ensuring that their contributions encourage the development of the creative and technical skills essential for future workforce needs. Notably, multi-year requests and various exclusions, including those based on discrimination, are not considered.
Environmental Education Computer Science & Engineering Emerging Technology Development +2 more

Rural Communities Opioid Response Program - Community Systems Development

Health Resources and Services Administration
Federal Government
American Samoa, Guam +7 more
Up to US $500,000
The Rural Communities Opioid Response Program (RCORP) - Community Systems Development aims to enhance behavioral health systems in rural areas by providing funding for the development and expansion of services. This initiative supports the establishment of formalized networks to boost operational and clinical capacity, ensuring effective implementation of evidence-based substance use disorder prevention, treatment, and recovery services tailored to community needs.
Rural Development Rural Health Care Community Services +1 more

UCAR Next Generation Fellowship

University Corporation for Atmospheric Research
Private
Canada, Mexico +1 more
US $40,000
The UCAR Next Generation Fellowship offers graduate students a unique opportunity to engage in Earth System Science research while addressing societal impacts. With a $40,000 fellowship over two years, participants can expect mentorship from UCAR leaders and professional development training. This program encourages interdisciplinary exploration, allowing fellows to collaborate closely with experts, attend conferences, and build lasting networks. It aims to empower diverse students as future change-makers in the field, fostering a commitment to equity and innovation.
Earth Science Public Policy Atmospheric Sciences +6 more

John Jamison Iron Mountain Education Fund Grant

Iron Mountain Foundation
Private
Asia, Australia +10 more
US $2,000
The John Jamison Iron Mountain Education Fund provides scholarships to encourage educational pursuits among the children of Iron Mountain employees. Established in 2004, it awards $2,000 to selected applicants and $4,000 to those majoring in STEM fields. Eligibility includes dependent children of full-time employees at the Director level and below, along with deceased employees' children. The number of scholarships varies annually based on available funds, supporting students in their quest for higher education.
Academic Scholarship Programs Mathematics STEM / STEAM Education +4 more

Public Humanities Projects (364098)

National Endowment for the Humanities
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $2,000,000
The National Endowment for the Humanities (NEH) is inviting applications for the Public Humanities Projects program, aimed at enhancing public understanding of the humanities through exhibitions, historic site interpretations, and public lectures. For 2027, topics of interest include Western civilization, literature, the 250th anniversary of the American Revolution, civic education, and cultural literacy. This initiative seeks to foster civil discourse and engage communities in meaningful discussions.
Art & Culture Humanities & Social Science Historic Preservation +2 more

Native American Library Services Basic Grant (2027)

Institute of Museum and Library Services (IMLS)
Federal Government
United States
US $6,000 - US $10,000
The Native American Library Services Basic Grant (NAB) aims to enhance library services for Native Communities. By supporting the acquisition of materials, programming, and staff training, the program empowers Tribal libraries to adapt to evolving information needs. This initiative fosters knowledge centers that contribute to community wellness and cultural preservation. Through targeted project activities, the NAB program ensures that libraries effectively meet their users' diverse needs, promoting accessibility and engagement across the nation.
Community Services Library & Information Science Native American Services +1 more

Clarence W. Seavers Citizenship Scholarship

Erie County Community Foundation
Private
United States
Unspecified amount
The Clarence W. Seavers Citizenship Scholarship supports graduates from Erie County, Ohio high schools pursuing degrees in Political Science or Computer Science/Technology. With a minimum GPA requirement of 3.0, this scholarship can be renewed for up to three additional years at the discretion of the Scholarship Advisory Committee, without considering financial need. It emphasizes leadership, spirituality, and community service, aiming to empower students to contribute positively to their communities.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Hertz Foundation Travel Fund

Fannie and John Hertz Foundation
Private
Countries
US $2,000 - US $5,000

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Foundation Travel Fund

The Hertz Foundation Travel Fund provides financial support to Hertz Fellows to advance their professional growth through conference travel and interdisciplinary engagement. Awardees receive a lump sum of $2,000 for domestic or $5,000 for international travel.

Supporting professional development

Established in 2025, this funding provides Fellows with critical support to enhance their career and professional development. Funding is designated to support travel to attend technical conferences, interdisciplinary or entrepreneurial convenings and workshops or seminars that catalyze new career paths, research directions or cross-sector collaborations.

Engineering Mathematics Science +1 more

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Private grants for nonprofits in South Carolina over $25K in average grant size

41 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081