Best Large Grants for Nonprofit Organizations in Oklahoma

Nonprofit 501(c)(3) and 509(a) organizations working in education, human services, conservation, health, or cultural programs can apply for McGraw Foundation support, including Oklahoma-based groups. McGraw Foundation provides U.S. nonprofits with US $2,000 - US $10,000 for general operating support, specific projects, and occasionally capital needs, with larger awards for especially promising efforts.

Graduate students pursuing research in drinking water quality, environmental science, or public health can receive US $3,000 to address current challenges in the water industry. Focused on water-related research, American Water Works Association invites applicants whose work may benefit communities, including those served by nonprofit organizations in Oklahoma.

Oklahoma nonprofit organizations working in human services, education, community enhancement, or journalism can seek general operating, one-time project, capital campaign, or sponsorship support. Focused on community impact, Inasmuch Foundation invites eligible nonprofits to submit one request per year through its online portal; individuals and for-profit entities are not supported.

Oklahoma 501(c)(3) nonprofits and independent emergency response organizations can access funding through Union Pacific Foundation’s Community Ties Local Grants, awarding US $5,000 - US $30,000 for community programs. Eligible projects may address safety, workforce development, community vitality, or environmental sustainability in communities served by Union Pacific, with an emphasis on diversity, equity, and inclusion.

Nonprofit 501(c)(3) organizations, public education institutions, and government entities in Oklahoma counties where Weyerhaeuser operates can seek funding for community programs. Weyerhaeuser Giving Fund supports large grants for affordable housing, youth development, environmental stewardship, human services, civic and cultural growth, workforce development, and diversity, equity and inclusion, with awards of more than US $1,000.

Nonprofit organizations addressing humanitarian aid, child welfare, health care, or self-sufficiency programs in Oklahoma can apply for funding to support women and children. The Father's Table Foundation provides up to US $750,000 for projects such as homelessness services, education, food security, microfinance, anti-trafficking, and related efforts that build resilience and long-term sustainability.

Nonprofit organizations in Oklahoma seeking support for arts and culture, education, healthcare, nature and wildlife, or social services can apply for funding from the Mary K Chapman Foundation. Grants of US $1,000 - US $10,000,000 may cover general operations, programs and projects, capital needs, and organizational capacity building.

Health and human service 501(c)(3) nonprofits in the Oklahoma City metropolitan area can receive up to US $10,000 to support direct services and programs. Grants from Employees Community Fund Of The Boeing Company help Oklahoma organizations addressing basic human needs, youth and family services, homelessness, food access, disability, senior support, and community health care and education.

Undergraduate-focused higher education institutions in Oklahoma conducting biomedical and health-related research can apply for up to US $375,000 to support small-scale research projects and enhance their research environment. The National Institutes of Health funds work in areas such as neuroscience, cancer, public health, HIV/AIDS, mental health, and related biomedical fields at baccalaureate degree-granting institutions with limited prior NIH support.

Early-career research scientists at academic or research institutions in low- or middle-income countries, including those collaborating with Oklahoma nonprofits, can apply for the Emerging Global Leader Award to support mentored clinical research careers. Grants from the National Institutes of Health help fund three to five years of protected time for global health-related studies across multiple disease areas.

Early-career research scientists in low- or middle-income countries can apply for the Emerging Global Leader Award from the National Institutes of Health, with approximately US $140,000 to support mentored health research and protected time. Oklahoma-based nonprofits hosting eligible LMIC investigators or collaborations may benefit from this multi-year career development support.

Nonprofit 501(c)(3) organizations running education-focused or youth-serving programs in Oklahoma may be eligible for grants from the John Ben Snow Memorial Trust, typically ranging from US $5,000 - US $20,000. Focus areas include academic support, literacy, journalism, arts education, youth initiatives, community services, environmental education, and historic preservation within its broader U.S. funding regions.

Oklahoma organizations planning health-related congresses, events, or initiatives that offer tangible marketing or recognition benefits to sponsors can seek corporate sponsorship support; funding is not for general operations. Biogen Foundation considers medical and scientific areas such as neurology, Alzheimer’s, ALS, multiple sclerosis, Parkinson’s, stroke, lupus, lymphoma, and related conditions.

Nonprofit 501(c)(3) organizations, including those in Oklahoma, can seek $5,000 - $50,000 for general operating support advancing regenerative agriculture, climate justice, healthy food access, and related environmental initiatives. Focused on grassroots, community-based efforts, Clif Family Foundation prioritizes U.S. groups with strong local ties and budgets under $8 million.

Nonprofit and conservation organizations working on regenerative agriculture and habitat conservation in Oklahoma can seek US $250,000 - US $750,000 to provide technical assistance to private landowners. National Fish and Wildlife Foundation’s Conservation Partners Program funds support for management planning, implementing best practices, Farm Bill program participation, and sharing conservation lessons to improve soil, water, and wildlife outcomes.

Nonprofit organizations in Oklahoma counties hosting Meta data centers can apply for Meta (Facebook)’s Data Center Community Grants Program, with awards of more than US $5,000 for high-impact community projects. Funding supports STEM education, economic opportunity, digital access, sustainability, health, and arts initiatives that benefit the immediate local community.

Free and charitable clinics in Oklahoma that are NAFC members can apply for the Healthcare Services Expansion Fund, offering US $30,000 - US $50,000 to launch or grow clinical programs for medically underserved patients. Funding can support areas like behavioral health, women’s health, telehealth, chronic disease management, mobile clinics, and other patient-centered care expansions.

Students pursuing natural resource and environmental fields in Oklahoma may be eligible for scholarships from the Community Foundation of Northern Illinois. With a mission to support higher education in conservation-related disciplines, this scholarship assists full-time college students preparing for careers in areas like ecology, forestry, hydrology, and environmental stewardship.

Oklahoma government units, public higher education components, regional planning districts, and qualifying nonprofits can receive US $5,000 - US $50,000 for solid waste, recycling, HHW, or composting equipment purchases. Oklahoma Department of Environmental Quality requires storage and maintenance plans, plus invoicing, monthly photos, and metrics to document use of this one-time equipment funding.

The OECD Conference Sponsorship aims to enhance scientific knowledge and provide essential information to influence policy decisions on sustainable resource use in food, agriculture, forestry, and fisheries. It supports international events that showcase innovative research and developments, inviting applications from scientists in these fields. The event sponsorship encourages collaboration among policymakers, industry, and academia, ensuring that research insights are effectively communicated and utilized in decision-making processes.

The RNRF Planning and Small Grants program provides funding up to $50,000 to support projects that enhance collaboration among community partners in addressing critical environmental issues. Eligible applicants must be 501c3 organizations in the U.S. and demonstrate multidisciplinary cooperation. Projects should align with RNRF's mission and focus areas, including air quality, biodiversity, and renewable energy. The initiative aims to create sustainable and impactful outcomes by bridging research and practical implementation.

The RNRF Rapid Response Grants provide essential funding up to $50,000 for projects adversely affected by the loss of federal support. The program aims to foster collaboration among organizations working towards sustainable environmental, social, and economic practices. Eligible applicants must be 501(c)(3) organizations in the U.S. and demonstrate multidisciplinary collaboration with RNRF member organizations, ensuring impactful outcomes in critical focus areas such as air quality, biodiversity conservation, and renewable energy.

The RNRF Implementation/Collaboration Grants support innovative projects that enhance collaboration among stakeholders to address critical challenges in environmental, social, and economic systems. Offering up to $200,000 for initiatives lasting 12 months or more, these grants aim to implement evidence-based practices and facilitate multidisciplinary teamwork. Eligible applicants must be from 501c3 organizations in the U.S., ensuring alignment with RNRF's mission and focus areas, fostering sustainable and impactful outcomes.

The Siletz Tribal Charitable Contribution Fund, established by the Confederated Tribes of Siletz Indians, has distributed over $16.3 million in grants since 1999. It supports charitable organizations and local governments in eleven Oregon counties, as well as Native American initiatives across the U.S. The fund prioritizes education, health, public safety, addiction prevention, housing, arts, and environmental preservation, ensuring the Tribe's commitment to community support and cultural heritage.

RBC Foundation – USA aims to enhance community quality of life by supporting non-profit organizations that promote diversity and positive change. In 2023, it awarded over $2.8 million in grants, prioritizing youth programs for ages 15-29, arts access for diverse populations, and mental well-being initiatives. The foundation encourages sustainable projects that foster economic independence, providing critical support for education, mental health, and cultural enrichment, thereby making a significant impact across various communities.

The Regional Conservation Partnership Program (RCPP) Classic for FY 2026 encourages collaboration between the NRCS and partners to address critical natural resource concerns through innovative projects. By co-investing with partners, the program aims to enhance conservation efforts on farms and private lands, ensuring equitable access to NRCS services. Selected proposals will be based on their potential impact and effective partnership management, ultimately improving environmental outcomes across designated Critical Conservation Areas.

The Anne and Henry Zarrow Foundation focuses on uplifting vulnerable populations through targeted grantmaking in Oklahoma, particularly the Tulsa area. Their mission emphasizes alleviating homelessness, improving healthcare access, supporting social services, and reducing hunger. Additionally, they provide funding for educational initiatives and community enrichment projects. The foundation prioritizes projects that empower individuals and foster community engagement, reflecting the founders' commitment to building a supportive and inclusive society.