Best Unrestricted Grants for Nonprofits in Texas

The Karim Thomas Ziyad Memorial Engineering Scholarship Fund supports students from Washington County or nearby areas pursuing a career in engineering, especially in Mechanical Engineering. Established in memory of Karim Thomas Ziyad, this scholarship aims to empower deserving students to achieve their educational goals. The fund is part of the Community Foundation of Washington County Maryland, which offers numerous scholarships to enhance educational opportunities for local students.

The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.

The National Science Foundation (NSF) is offering Postdoctoral Research Fellowships in Biology to support innovative research at the intersection of Artificial Intelligence (AI) and Biological Sciences. These fellowships aim to cultivate expertise in both fields, enabling scientists to leverage AI for breakthroughs in biotechnology and bio-system design. The program encourages proposals that utilize existing biological data and infrastructure to enhance discovery and innovation, ultimately benefiting human lives and the U.S. economy.

The Kors, Lois E., Educational Scholarship, established by the Beatrice Educational Foundation, aims to support Beatrice High School graduates in pursuing higher education. With a strong commitment to academic achievement and civic involvement, the Foundation awards over $55,000 annually in scholarships. Applicants must demonstrate financial need, citizenship, and academic merit. This scholarship encourages students to enter the teaching profession, providing essential funds to help them achieve their educational goals.

Beekhuis Scholarship

Award:

• One time award of $4,000.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The ACS Congressional Fellowship Program offers trained scientists the chance to engage in the policy-making process, providing critical information to lawmakers on science-related issues. Each year, two fellows are placed in the offices of Senators, Representatives, or Committees, with the aim of educating them on how science policy is formed. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of whether they hold a doctorate.

The Fred C. Gloeckner Foundation Research Fund Grant, established in 2024, supports innovative floriculture research and education. This partnership between the Gloeckner Foundation and AFE aims to enhance advancements in floriculture through substantial funding. Grants are available for university and college projects, emphasizing significant research importance and public accessibility. Projects can include funding for research assistants and must be accompanied by detailed outlines. Indirect costs and salaries are not covered.

The FY 2023 Disaster Supplemental grant aims to support communities affected by major disasters, such as Hurricanes Ian and Fiona, by funding both construction and non-construction projects. This initiative focuses on long-term economic recovery strategies to address the challenges faced in areas with federal disaster declarations. Additionally, the Economic Development Administration has launched the Economic Development Grants Experience (EDGE) platform to enhance the efficiency and transparency of the grant management process.

The Musician Health & Services Program, funded by The Jeremy Willson Charitable Trust, provides essential support for professional musicians facing financial hardships due to medical or mental health issues. This program offers navigation assistance to help applicants access healthcare resources and financial aid for living and medical expenses. Eligible participants include musicians and music industry professionals residing in Oregon or Clark County, Washington. The program aims to alleviate the financial burdens associated with medical treatments and living costs.

The John M. O'Quinn Foundation Grant, established in 1986, has contributed over $192 million to various charitable activities, focusing primarily on Houston and its surrounding areas. The Foundation supports tax-exempt organizations and governmental units, emphasizing conservation, education, healthcare, and programs for underprivileged youth. Grants are not available for type III supporting organizations, individuals, or foreign charities, ensuring a targeted impact within the local community.

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Easterby Family Scholarship ($7,000)

This renewable scholarship is for students from Laurens County, South Carolina who are pursuing graduate or post-graduate education in the fields of theology or medicine. 

The Bruce J. Heim Foundation Grant supports organizations that empower young individuals with exceptional potential in academics and the arts. Established in 1986, this private foundation aims to provide financial assistance that fosters skill enhancement and personal growth. The Board evaluates grant requests monthly, assessing the viability and significance of each organization’s project. The Foundation's goal is to inspire recipients to realize their potential and contribute to philanthropic efforts, echoing the support they received.

The Read Conmigo School Impact Grants, offered by The Kemper Foundation, provide $10,000 grants annually to Title I elementary schools in select locations. Aimed at supporting dual-language initiatives, eligible schools must have an established Spanish-English program and be located in California, Florida, or Texas. Funds can be used for resources, technology, professional development, and community engagement. Applications must be submitted by the school principal by the deadline.

The Tuttleman Foundation, established in Philadelphia in 2003, provides grants ranging from $1,000 to $250,000 to 501c3 organizations. Guided by the legacy of Stanley and Edna Tuttleman, the foundation focuses on areas such as education, community building, health care, arts and museums, basic human services, and spirituality. Their engaged philanthropy aims to support enduring benefits for the communities they serve, reflecting the founders' commitment to impactful giving.

The NeuroNEXT Small Business Innovation program invites small businesses to apply for exploratory clinical trials involving investigational agents, including drugs, biologics, and devices. These trials aim to gather critical data to support the design of future clinical studies, particularly focusing on diseases aligned with the NINDS strategic plan. Applications are due by 5:00 PM local time of the applicant organization, emphasizing the importance of timely submissions.

The Indigo Oak Fund, based in Colorado, is dedicated to enhancing education, the arts, and social justice, particularly through its Equal Justice Under the Law Grant Program. This initiative supports organizations that promote fairness in the justice system, rehabilitation, and civic engagement. By funding programs focused on personal empowerment and equal opportunities, the fund aims to foster lifelong learning and improve lives, particularly for women and children in need.

The Katie Cannon Scholarship honors Rev. Dr. Katie Geneva Cannon, a pioneering figure in the Presbyterian Church (U.S.A.). This scholarship aims to empower Presbyterian women of color, clergywomen, and college women by providing financial assistance for leadership development events and educational opportunities. It promotes spiritual growth and mission involvement within the church, ensuring that women are equipped for greater service and leadership roles. This fund is part of the Women's Ministry Fund at the Presbyterian Mission Agency.

The Fidelity Foundation Grant supports nonprofit organizations that aim for high impact in areas like Arts, Education, and Health. Eligible applicants must be 501(c)(3) organizations with operating budgets over $1 million and project budgets of at least $100,000. The foundation seeks transformative projects that enhance efficiency and sustainability. However, it does not fund start-up organizations, capital campaigns without prior support, or emergency funding, ensuring a focus on long-term effectiveness.

The Alexandra Hallock Capacity Building Grant for Small Nonprofits, established in 2024, honors the legacy of Alexandra Hallock by supporting small nonprofits focused on human rights, women's empowerment, and LGBTQ+ causes. This grant offers a one-time $20,000 unrestricted funding along with pro-bono capacity building support. It aims to strengthen organizational infrastructure and governance, ensuring impactful community engagement. Eligible organizations must be 501(c)3 nonprofits with revenue under $400,000, operating for at least one year, and based in the U.S.

The David G. & Jacqueline M. Braithwaite Scholarship in Chemistry, offered by the East Texas Communities Foundation, supports graduating seniors from East Texas counties majoring in chemistry. This renewable scholarship emphasizes the importance of education in achieving dreams, with a preference for chemistry or biochemistry majors. Although financial need is not a consideration, students attending any college in the United States can apply, enabling broader opportunities for aspiring chemists.

The East Texas Estate Planning Council Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors pursuing careers in accounting, law, finance, banking, investments, insurance financial planning, or philanthropic planning. This scholarship reflects a commitment to education and aims to alleviate financial barriers for students in East Texas. Applicants must demonstrate financial need, with FAFSA required, and can attend any college in the United States for one year.

The Donaghue Foundation's Greater Value Portfolio Grant Program aims to enhance healthcare value by funding innovative research projects for two years, with awards up to $400,000. It encourages proposals that address issues such as high costs, disparities, and inefficiencies in care. Eligible applicants include Ph.D. researchers at nonprofit institutions partnered with healthcare organizations. The program seeks actionable solutions to improve patient care and reduce the burden of low-value healthcare on communities.

The David G. & Jacqueline M. Braithwaite Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors from East Texas planning to major in biology, mathematics, engineering, or related fields. This scholarship aims to empower students pursuing careers in medicine, veterinary medicine, or biotechnology. Financial need is not a consideration, and the scholarship is renewable, reflecting a commitment to education and community development in East Texas.

The Oak Advisors Scholarship of Excellence, offered by the Community Foundation of the Lowcountry, supports southern Beaufort County high school seniors pursuing a major in business, economics, or finance. Established by philanthropic leaders, the scholarship recognizes students for their academic achievements, talents, and community involvement. With a minimum GPA of 3.2 required, this scholarship aims to empower students to make a positive impact in their communities.