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Best Wythe County Grants for Nonprofits in Virginia

Looking for grants for 501(c)(3) nonprofit organizations working in Wythe County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,350 Results based on applied filters

Intervention Research to Improve Native American Health (R21 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Intervention Research to Improve Native American Health (R21 Clinical Trials Optional) aims to support exploratory studies focused on enhancing health outcomes within Native American populations. This initiative encourages research that addresses critical health disparities, tests new interventions, and develops culturally appropriate solutions to improve health and well-being. Applications are encouraged to include community-driven research, addressing unique sociopolitical and environmental challenges faced by these populations, ultimately aiming to reduce morbidity and mortality.
Native American Services Indigenous Health Systems Health Disparities & Social Determinants of Health

Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (350160)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
This funding opportunity announcement aims to enhance health interventions for Native American populations. It supports research to develop, adapt, and test culturally informed health promotion and disease prevention strategies. The initiative addresses significant health disparities faced by these communities, emphasizing sustainable and adaptable solutions. Researchers are encouraged to build on community strengths and resilience, focusing on effective dissemination and integration of interventions. The program welcomes applications targeting diverse Native American groups, including Alaska Natives and Native Hawaiians.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

Cohort Studies of HIV/AIDS and Substance Use (U01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.
HIV / AIDS Addiction & Substance Use Disorders

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This funding opportunity supports research aimed at improving health among Native American populations by developing, adapting, and testing interventions. It addresses significant health disparities and seeks culturally informed solutions. The initiative encourages research that informs intervention strategies tailored to community needs, focusing on sustainability and scalability. The program is vital for enhancing health equity and resilience in Native American communities, ultimately aiming to reduce morbidity and mortality through effective health interventions.
Health Disparities & Social Determinants of Health Native American Services Indigenous Health Systems

O'Reilly Automotive Foundation Grant

O'Reilly Automotive Foundation Inc
Private
United States
Unspecified amount
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
Economic Services & Development Homelessness Services Food Access & Hunger +12 more

Research Experiences for Undergraduates (348985)

National Science Foundation (NSF)
Federal Government
United States
US $5,000 - US $500,000
The Research Experiences for Undergraduates (REU) program, funded by the National Science Foundation (NSF), promotes active research participation among undergraduate students across various research areas. It supports two mechanisms: REU Sites, which engage multiple students in ongoing research, and REU Supplements, which enhance existing NSF-funded projects. Participants must be U.S. citizens, nationals, or permanent residents, and each REU opportunity has its unique application process.
Geoinformatics & Geospatial Sciences Biology Physics +14 more

Rails-to-Trails Conservancy: Trail Grants

Rails To Trails Conservancy
Private
United States
US $10,000 - US $25,000

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

Trail Creation & Maintenance Pedestrian & Bike-Friendly Infrastructure

Trail Accelerator Grants- Spring Cycle Planning and Design

International Mountain Bicycling Association
Private
United States
US $10,000 - US $30,000
The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.
Trail Creation & Maintenance Biking Pedestrian & Bike-Friendly Infrastructure

Mathematical Sciences Postdoctoral Research Fellowships

National Science Foundation (NSF)
Federal Government
United States
Up to US $190,000
The Mathematical Sciences Postdoctoral Research Fellowships (MSPRF) aim to support emerging leaders in mathematics and statistics. These fellowships enhance participants' research environments, ensuring significant scientific development. Awardees can choose between a Research Fellowship or a Research Instructorship, with funding available for research across various mathematical and statistical disciplines. Proposals are submitted directly to the NSF, and fellows must affiliate with eligible institutions or organizations.
Mathematics

Mathematical Sciences Research Institutes (349343)

National Science Foundation (NSF)
Federal Government
United States
US $1,500,000 - US $6,500,000
The Mathematical Sciences Research Institutes, supported by the National Science Foundation, serve as critical national resources aimed at advancing research in mathematics and statistics. These institutes facilitate the discovery and dissemination of knowledge while enhancing connections with related fields. Their activities attract top mathematical minds to tackle pressing problems and engage a diverse array of U.S.-based researchers, ultimately bolstering the impact of mathematical sciences across various disciplines.
Mathematics

Founders Project Fulfillment Grant

Children's Theatre Foundation of America (CTFA)
Private
United States
US $30,000
The Founders Project Fulfillment Grant, offered by the Children's Theatre Foundation of America (CTFA), is dedicated to supporting 501(c)(3) IRS-certified theatres with a strong commitment to artistic excellence for young audiences. Eligible organizations must have a minimum operating budget of $1,000,000 and a proven track record of diversity in leadership, making this grant a vital resource for fostering inclusive theatre experiences for children and families.
Theater Youth Involvement in the Arts Arts / Culture Access & Participation

Ash Grove Charitable Foundation Grant

Ash Grove Charitable Foundation
Private
United States
Up to US $25,000
The Ash Grove Charitable Foundation Grant supports public charities with 501(c)(3) status, focusing on capital projects that enhance community life in states where Ash Grove operates. With a commitment to environmental sustainability, education, and human services, the Foundation prioritizes funding for renovation and construction projects. Grants typically reach up to $25,000, aiming to foster better living standards and support local initiatives that are vital for community growth and resilience.
Community Services

Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,375,000
The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.
Cancer / Oncology Nanomaterials & Nanotechnology

Bell's Brewery Small Grassroots Grants

Bell's Brewery, Inc.
Corporate
District of Columbia, United States
US $500 - US $5,000
Bell's Brewery Small Grassroots Grants support projects focusing on water stewardship across the Great Lakes watershed. With grant amounts ranging from $500 to $5,000, eligible organizations can apply for funding to improve ecosystem health, enhance public health through better water resource management, and promote resilience against climate-related water risks. This initiative highlights Bell's commitment to environmental stewardship and community support in all 50 states and DC.
Water Resource Management Environmental Stewardship Climate Change Resilience & Equity +3 more

Pioneering Aerospace Capabilities, Engineering and Research (PACER)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
United States
Unspecified amount
The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program is a 20-year Broad Agency Announcement (BAA) by the US Air Force aimed at advancing innovative aerospace technologies. This initiative encourages white papers and proposals for research and development to enhance technology readiness levels. It is designed to provide the warfighter with a decisive advantage through transformative technology solutions. Multiple awards are anticipated, allowing for a range of project durations and funding values.
Aerospace Engineering

Wild Animal Initiative: Seed Grants

Wild Animal Initiative
Private
Afghanistan, Albania +189 more
Up to US $30,000
The Wild Animal Initiative offers Seed Grants to support innovative projects in wild animal welfare research. These grants aim to facilitate early-career researchers and established scientists in testing new techniques and approaches that incorporate welfare assessments into ecological studies. The program emphasizes cost-effective solutions, focusing on improving the welfare of wild animals. Successful proposals will explore diverse themes such as wild fish welfare and near-term welfare interventions to address urgent animal welfare challenges.
Wildlife Health Ichthyology (Fish)

Arctic Research Opportunities (349724)

National Science Foundation (NSF)
Federal Government
Canada, Greenland +1 more
Up to US $330,000
The National Science Foundation (NSF) seeks proposals for Arctic research to enhance understanding of the rapidly changing Arctic environment and its social systems. This initiative encourages innovative research that connects the Arctic region with lower latitudes, aiming to improve projections of future changes. Collaborations with federal and international partners are encouraged for co-reviewing proposals. Proposals that extend beyond the Arctic must clearly articulate their relevance to Arctic knowledge advancement.
Oceanography Hydrology Environment +7 more

The Commonwealth History Fund

Virginia Historical Society
Private
Virginia
Unspecified amount
The Commonwealth History Fund, established by the Virginia Museum of History & Culture, aims to enhance history education and preservation projects across Virginia. With annual grants of approximately $400,000, totaling nearly $2 million in its first five years, the Fund supports diverse initiatives that focus on underserved communities and significant historical narratives. Managed in partnership with the Virginia Department of Historic Resources, it emphasizes project urgency, community impact, and the qualifications of applicants.
Historical Records & Archives Historic Preservation

Leonard-Litz Foundation: LGBTQ+ Community Grants

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard Litz Foundation supports LGBTQ+ organizations through grants that promote health, wellness, crisis intervention, racial justice, advocacy, and social assistance. Priority is given to organizations in the northeast U.S. and those serving communities of color and transgender individuals. Applications that clearly link funding requests to specific needs will receive stronger consideration. The foundation aims to foster a supportive environment for the LGBTQ+ community to thrive.
LGBTQIA+ Services Sexuality & LGBTQIA+ Rights

Leonard-Litz Foundation: LGBTQ+ Advocacy Fund Grant

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard-Litz Foundation's LGBTQ+ Advocacy Fund Grant aims to empower LGBTQ+ individuals by funding organizations that advocate for their rights and well-being. With a focus on health, wellness, and racial justice, the fund supports projects that require significant investment for impactful change. Prioritizing partnerships that serve vulnerable communities, including people of color and transgender individuals, this grant fosters equality and addresses systemic inequalities faced by LGBTQ+ people, especially in the northeast U.S.
Sexuality & LGBTQIA+ Rights LGBTQIA+ Services

We Raise Foundation: Emerging Leader Grant

We Raise Foundation
Private
United States
US $15,000
The We Raise Foundation's Emerging Leader Grant supports individuals aged 20-35 at Christian organizations developing innovative programs addressing poverty, violence, and inequality. With a total of $15,000 over two years, the grant allocates $10,000 for program support and $5,000 for leadership development, including coaching and conferences. This initiative aims to foster impactful leaders who inspire, communicate effectively, and engage deeply with their communities, ultimately creating lasting change.
Civic Leadership Development Christianity Poverty Alleviation & Services +2 more

Middle School Music Grant

Peter R Marsh Foundation
Private
United States
US $1,250
The Middle School Music Grant, offered by the Peter R Marsh Foundation, aims to enrich the musical education of public middle school music teachers across the U.S. By facilitating performances at senior facilities, the grant fosters emotional connections between students and seniors, while providing essential classroom equipment. Funds cover music supplies, instruments, and transportation, ensuring students have the resources to thrive musically and socially. This initiative not only enhances music education but also promotes community engagement and empathy.
Music Education

Just Tech Fellowship

Social Science Research Council
Private
United States
Approximately US $200,000
The Just Tech Fellowship, supported by the Social Science Research Council, aims to empower diverse researchers and practitioners to address injustices arising from new technologies. With a two-year award of $100,000 annually, this fellowship fosters collaboration and community engagement, promoting equitable tech futures. It focuses on the intersection of technology and social justice, encouraging insights from historically marginalized groups to inform structural change and create a more just society.
Technology Access & Digital Literacy Emerging Technology Development

Health and Health Care Disparities Among Persons Living with Disabilities (R01 - Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Health and Health Care Disparities grant aims to support innovative research that addresses the health challenges faced by individuals with disabilities, particularly in communities experiencing health disparities. Key application deadlines span from February 2024 to October 2026. This funding opportunity invites research proposals that explore the underlying factors affecting the health and well-being of these populations, promoting interventions that can lead to significant improvements in health equity.
Health Disparities & Social Determinants of Health Disability Care & Services Disability Rights & Justice

ACLS Project Grants for HBCU Faculty

American Council of Learned Societies
Association/Society
United States
Up to US $10,000
The ACLS Project Grants for HBCU Faculty provide up to $10,000 to support early-stage project design and development over a 12- to 15-month period. This funding facilitates exploratory research and the advancement of existing projects, while offering networking and mentorship opportunities. Applicants must be employed at an HBCU and possess an MA or PhD in humanities or social sciences. The initiative encourages innovative research methods and community engagement, with a focus on higher education outcomes.
Humanities & Social Science

HBCU Faculty Fellowships

American Council of Learned Societies
Association/Society
United States
Up to US $50,000
The ACLS HBCU Faculty Fellowships provide financial support ranging from $30,000 to $50,000 for faculty at Historically Black Colleges and Universities to advance their research projects. The fellowships encourage innovative research outcomes, including scholarly articles and community-engaged projects. Awardees also benefit from mentoring and networking opportunities, with additional funding for their institutions to support humanities programming. This initiative promotes diverse scholarship and collaboration across disciplines, enhancing the academic landscape for HBCU faculty.
Humanities & Social Science

Lawren H. Daltroy Preceptorship in Health Communication

Rheumatology Research Foundation
Private
United States
Up to US $15,000
The Lawren H. Daltroy Preceptorship in Health Communication aims to enhance patient-clinician communication by providing a one-on-one learning experience for trainees and junior researchers. Funded by the Rheumatology Research Foundation, it offers up to $15,000 over one year for eligible candidates with no prior R01 funding. The program focuses on projects that improve understanding of effective communication in healthcare settings, addressing critical issues such as health literacy and shared decision-making.
Musculoskeletal Diseases Patient Care & Services Medical Education & Professional Training

Wythe County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Wythe County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Virginia

Average Grant Size

What's the typical amount funded for Virginia?

Grants are most commonly $113,117.

$113,117

Total Number of Grants

What's the total number of grants in Wythe County Grants for Nonprofits year over year?

In 2024, funders in Virginia awarded a total of 69,694 grants.

2022 66,520

2023 66,322

2024 69,694

Top Grant Focus Areas

Among all the Wythe County Grants for Nonprofits given out in Virginia, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Wythe County Grants for Nonprofits changing over time?

Funding has increased by 9.79%.

2022 $6,521,474,631

2023 $7,159,569,220
9.78%

2024 $7,860,695,969
9.79%

Virginia Counties That Receive the Most Funding

How does grant funding vary by county?

Fairfax County, Arlington County, and Alexandria City receive the most funding.

County Total Grant Funding in 2024
Fairfax County $2,293,731,782
Arlington County $2,240,636,439
Alexandria City $719,704,106
Richmond City $452,557,663
Loudoun County $376,230,846

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