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Best Brule County Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Brule County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

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9,007 Results based on applied filters

National Glaucoma Research RFP: Standard Awards

BrightFocus Foundation
Corporate
United States
Up to US $150,000
The National Glaucoma Research Program, funded by BrightFocus Foundation, aims to support groundbreaking research in glaucoma. Established in 1978, the program has awarded over $35 million to 32 projects focusing on understanding and treating this disease. The Standard Awards provide $150,000 over two years for researchers with preliminary data to further their work. Eligible institutions must be non-profit and demonstrate their tax-exempt status to receive funding, fostering innovative solutions for glaucoma treatment.
Eye Diseases & Disorders

Michael & Susan Dell Partnerships

Michael & Susan Dell Foundation
Private
Africa, India +2 more
Unspecified amount
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Poverty Alleviation & Services Education - Preschool / Early Learning Education - K through 12 +4 more

The Standard's Corporate Giving Program

The Standard Charitable Foundation
Corporate
United States
US $500 - US $25,000
The Standard's Corporate Giving Program emphasizes community support and employee engagement, reflecting its foundational mission to enhance financial well-being. Established in 1906, the program focuses on Healthy Communities, Disability and Empowerment, Cultural Development, and Education. With a funding range of $500 to $25,000, it aims to make a substantial impact in the lives of individuals and families facing challenges. The Standard Charitable Foundation, launched in 2006, further extends this commitment by supporting organizations that align with its philanthropic goals.
Workforce Preparation & Job Readiness Education - Preschool / Early Learning Basic Human Needs +12 more

Edwards Lifesciences Foundation Grants

Edwards Lifesciences Foundation
Private
United States
Unspecified amount
The Edwards Lifesciences Foundation Grants program aims to improve the health of underserved communities by supporting initiatives focused on education, screening, and treatment of cardiovascular disease. The Foundation seeks to enhance care access for patients, promote awareness of heart health, and foster community engagement through volunteer opportunities. By 2025, the goal is to positively impact the lives of 2.5 million patients affected by structural heart issues. The program emphasizes collaboration and innovation in healthcare.
Cardiovascular Diseases & Systems

Marcy Shulman Memorial Organization Grant Program

Colburn-Keenan Foundation
Private
United States
Up to US $5,000
The Marcy Shulman Memorial Organization Grant Program, established by the Colburn-Keenan Foundation, supports organizations improving the lives of individuals with chronic illnesses, particularly within the bleeding disorders community. Proposals should enhance health and quality of life, with examples including educational programs and facility upgrades. Only 501(c)3 organizations are eligible, and they may receive one grant per cycle. Applications must be submitted at least two months prior to the project start date.
Hematological Systems Chronic Illnesses

Psychosocial Research - PSR Postdoctoral Fellowship

Craig H. Neilsen Foundation
Corporate
Canada, United States
Up to US $200,000
The Craig H. Neilsen Foundation's Psychosocial Research Postdoctoral Fellowship supports early-career researchers in spinal cord injury (SCI) psychosocial studies. It aims to enhance professional interest and training in this vital field, focusing on areas such as caregiving, employment, and technology access. The fellowship offers mentored training, covering salary and up to $35,000 for non-personnel costs over two years, ensuring comprehensive support for fellows to advance their careers.
Spinal Cord Injuries

Jason Debus Heigl Foundation Grant

Jason Debus Heigl Foundation
Private
United States
Unspecified amount
The Jason Debus Heigl Foundation Grant supports nonprofit organizations dedicated to animal welfare in the U.S. It aims to maximize the benefit to animals through education, spay and neuter initiatives, and positive advocacy. The foundation focuses on impactful programs, encouraging grants that align with their mission to end animal overpopulation and cruelty. Eligible applicants must be registered 501(c)(3) nonprofits, while individuals and political lobbying efforts are excluded from funding.
Animal Welfare - Domestic Animals & Pets

Folke H. Peterson Foundation Grant

Folke H Peterson Charitable Foundation
Private
United States
US $5,000 - US $20,000
The Folke H. Peterson Foundation Grant aims to prevent cruelty to animals and enhance their welfare. It provides funding for organizations focused on animal protection, medical assistance, and food supplies, ensuring these efforts directly benefit animals. Eligible applicants must be 501(c)(3) tax-exempt organizations within the United States. Notably, the foundation will not support any organization involved in euthanizing healthy animals, reinforcing its commitment to animal welfare.
Animal Welfare - General

Community Possible Grant Program: Play, Work, & Home Grants

US Bancorp Foundation
Private
Arizona, Arkansas +24 more
Unspecified amount
The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.
Museums & Cultural Institutions Art Education Arts / Culture Access & Participation +16 more

Owen Family Foundation Grant

Louis and Peaches Owen Family Foundation
Private
United States
Unspecified amount
The Owen Family Foundation Grant supports charitable organizations primarily in East Texas and the Minneapolis/St. Paul area, focusing on health, education, human services, and religious initiatives. Organizations must have a 501(c)(3) status and past funding is required for Twin Cities applicants. The foundation is committed to promoting philanthropy and ensuring access to funding for eligible charities, while maintaining a non-discriminatory policy.
Health & Medicine Education Human & Social Services +2 more

Ray Rowe Trusts for Animals Grant

Ray Rowe Trusts for Animals
Private
United States
Unspecified amount
The Ray Rowe Trusts for Animals Grant provides funding for programs aimed at the welfare of animals, particularly dogs, and the protection of wildlife habitats, especially for canid species. There are no application deadlines; grants are distributed from early March until the year's funding is exhausted, typically by the end of November. To apply, organizations must hold 501(c)(3) status, while general administrative costs are generally not supported.
Animal Welfare - General Mammalian Conservation Ornithological Conservation +1 more

Elizabeth Nash Foundation Scholarship

Elizabeth Nash Foundation
Private
United States
US $1,500 - US $2,500
The Elizabeth Nash Foundation Scholarship supports individuals affected by cystic fibrosis (CF) in their pursuit of higher education. Since its inception in 2005, over 200 scholarships ranging from $1,000 to $2,500 have been awarded to undergraduates and graduates at accredited U.S. institutions. The selection process considers academic performance, character, leadership, community service, and financial need. To qualify, applicants must have a CF diagnosis and be U.S. citizens.
Education - Higher Education Cystic Fibrosis

Career Guidance for Trainees Grant

Burroughs Wellcome Fund
Private
Canada, United States
US $15,000 - US $25,000
The Career Guidance for Trainees Grant, offered by the Burroughs Wellcome Fund, aims to enhance the career development of early career administrators focused on PhD scientists. This grant supports a workshop that equips participants with research evaluation skills to create impactful career-focused interventions. Participants will receive a $15,000 grant to implement their projects, develop networks, and share findings at national meetings, fostering a diverse scientific workforce essential for research innovation and public service.
Workforce Preparation & Job Readiness Career / College Preparation

Ittleson Foundation: Mental Health Grant Program

Ittleson Foundation
Private
United States
Unspecified amount
The Ittleson Foundation, established in 1932, focuses on enhancing mental health, AIDS prevention, and environmental initiatives. It funds not-for-profit organizations aiming to improve public policy and the lives of citizens. The Foundation is particularly interested in innovative projects addressing mental health stigma, advancing preventative efforts, and supporting underserved populations. While it funds new initiatives, it does not typically support capital projects, endowments, or direct service programs outside New York City.
Mental Health & Psychiatric Diseases

Conagra Brands Foundation- Community Impact Grants

Conagra Brands Foundation
Corporate
United States
Unspecified amount
The Conagra Brands Foundation offers Community Impact Grants to nonprofit organizations in the USA that address food insecurity and promote healthy lifestyles. Eligible organizations must align with core focus areas like food access, nutrition education, and cooking skills. Grants support initiatives that foster community engagement and provide entrepreneurial skills. Nonprofits must uphold a non-discrimination policy protecting various characteristics. Applications are accepted through a Letter of Intent from January 1 to February 15, 2025.
Food Access & Hunger Agriculture Nutrition & Healthy Eating

AAD Annual Meeting Registration Scholarship Program

American Academy of Dermatology
Association/Society
United States
Unspecified amount
The AAD Annual Meeting Registration Scholarship Program offers scholarships to international dermatologists, excluding those from the U.S. and Canada, to support their attendance at the AAD's Annual Meeting. Each country can nominate up to two applicants, who will receive complimentary registration, access to a post-graduate session, and an invitation to the International Scholarship Recipient Reception. This initiative promotes global participation in dermatology.
Skin Diseases & Dermatology

Clarence S. Livingood, MD, Memorial Award and Lectureship

American Academy of Dermatology
Association/Society
United States
US $10,000
The Clarence S. Livingood, MD, Memorial Award and Lectureship recognizes outstanding contributions to dermatology. Established by the Department of Dermatology at Henry Ford Hospital, it honors Dr. Livingood's legacy. The award includes a $10,000 cash prize and the opportunity to present a lecture at the AAD Annual Meeting. Nominations are accepted annually until January 15, remaining active for five years, and are open to experts beyond dermatologists, emphasizing communication and expertise in relevant issues.
Skin Diseases & Dermatology

Everett C. Fox, MD, Memorial Lectureship

American Academy of Dermatology
Association/Society
United States
US $10,000
The Everett C. Fox, MD, Memorial Lectureship honors a distinguished dermatologist and offers a $10,000 award to the selected lecturer, who will present a 30-minute lecture at the AAD's Innovation Academy. Nominations are open until June 15 for the upcoming selection cycle, with entries held for five years. Candidates must be practicing clinical dermatologists with proven communication skills, ensuring the recognition of expertise within the field.
Skin Diseases & Dermatology

AAD Young Investigator Awards

American Academy of Dermatology
Association/Society
Canada, United States
US $6,000
The AAD Young Investigator Awards recognize promising dermatology researchers in the U.S. and Canada, offering a $6,000 prize and plaque for outstanding research in either basic/translational or clinical tracks. Eligible applicants must have a DO, MD, or PhD, and their research should be completed and submitted for publication. The application window is open from June 1 to September 1, encouraging diversity within research topics and applicants.
Skin Diseases & Dermatology

Allen Foundation Grant - Academic Research

Allen Foundation Inc.
Private
United States
Unspecified amount
The Allen Foundation Grant supports initiatives that enhance human nutrition through research, education, and training. It prioritizes projects that develop nutritional programs, including mandatory nutrition courses in medical schools and sustainable food systems. Eligible applicants must be U.S.-based non-profits or governmental entities with a focus on nutrition education and research. The foundation encourages proposals that include matching funds and has specific criteria for academic research and budgetary self-sufficiency.
Nutrition & Healthy Eating

Donaghue Foundation: Another Look Grant

Patrick and Catherine Weldon Donaghue Medical Research Foundation
Private
United States
Unspecified amount
The Donaghue Foundation's Another Look Grant focuses on enhancing health and well-being for older adults in long-term care facilities. It prioritizes research that utilizes existing datasets and includes stakeholders to inform project development. High-priority topics include improving palliative care, workforce innovations, and addressing disparities in care quality. This program is open to PhD investigators from tax-exempt institutions in the U.S., aiming to foster impactful health-related research that enhances care quality for seniors.
Residential Care & Nursing Homes

Donaghue Foundation: Greater Value Portfolio Grant Program

Patrick and Catherine Weldon Donaghue Medical Research Foundation
Private
United States
Up to US $500,000
The Donaghue Foundation's Greater Value Portfolio Grant Program aims to enhance healthcare value by funding innovative research projects for two years, with awards up to $400,000. It encourages proposals that address issues such as high costs, disparities, and inefficiencies in care. Eligible applicants include Ph.D. researchers at nonprofit institutions partnered with healthcare organizations. The program seeks actionable solutions to improve patient care and reduce the burden of low-value healthcare on communities.
Health Care Access & Delivery Health & Medicine Health Policy & Advocacy +1 more

North Central Soybean Research Grant Program (NCSRP)

North Central Soybean Research Program (NCSRP)
Private
United States
Unspecified amount
The North Central Soybean Research Grant Program (NCSRP) aims to enhance soybean production through collaborative research and outreach. By investing in innovative projects, it addresses key challenges in soybean yield, profitability, and environmental sustainability. The program encourages proposals that focus on genetic improvement, pest control, and production practices tailored for the North Central region. Funded projects are expected to deliver practical benefits to soybean farmers while fostering communication and collaboration among stakeholders in the industry.
Agricultural Crops

Family Fun & Connections Event Grant Program

Colburn-Keenan Foundation
Private
United States
US $1,000
The Family Fun & Connections Event Grant Program, initiated by the Colburn-Keenan Foundation, aims to support community engagement through events for families affected by bleeding disorders. This program, established after a successful 10th Anniversary Celebration, offers $1,000 grants for various fun activities such as dance parties, BBQs, and outdoor adventures. It emphasizes the foundation's commitment to enhancing the lives of those with chronic illnesses and promoting community strength and advocacy.
Hematological Systems Chronic Illnesses

Weil Foundation Grant

The Weil Foundation
Private
United States
Up to US $300,000
The Weil Foundation provides grants to advance integrative medicine through education, research, and policy reform. Primarily aimed at non-profit healthcare organizations and medical schools, these grants support the development of educational programs in integrative medicine. Each grant is awarded for one year, with the possibility for recipients to apply for additional funding in subsequent years. The Foundation emphasizes cooperation, respect for grant-seekers, and transparency in its operations.
Integrative & Alternative Health

KTGF Fellowship Programs

Klingenstein Third Generation Foundation
Private
United States
Up to US $100,000
The KTGF Fellowship Programs, funded by the Klingenstein Third Generation Foundation, offer $100,000 over two years to support post-doctoral and junior faculty research on ADHD and depression in children, particularly from low-income and under-resourced backgrounds. This initiative aims to foster promising early-career scientists while producing impactful research that benefits affected children and families. Applications are accepted from September 1 to December 15, with specific eligibility criteria outlined for candidates.
Mental Health & Psychiatric Diseases Children’s Mental Health Depression / Anxiety

BMS Corporate Giving

Bristol Myers Squibb Foundation Inc
Private
United States
Unspecified amount
Bristol Myers Squibb is dedicated to enhancing healthcare and advancing scientific knowledge through its Corporate Giving program. By supporting various organizations, BMS aims to improve health equity and access to essential medicines for underserved populations. Their focus includes charitable donations, medical education, and community support initiatives. This commitment reflects BMS's goal to make a positive impact on patients' lives and foster strong communities where their employees work and live.
HIV / AIDS Cancer / Oncology Cardiovascular Diseases & Systems +5 more

Brule County Grants for Nonprofits Highlights

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Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Dakota

Average Grant Size

What's the typical amount funded for South Dakota?

Grants are most commonly $110,621.

$110,621

Total Number of Grants

What's the total number of grants in Brule County Grants for Nonprofits year over year?

In 2024, funders in South Dakota awarded a total of 6,460 grants.

2022 6,268

2023 6,140

2024 6,460

Top Grant Focus Areas

Among all the Brule County Grants for Nonprofits given out in South Dakota, the most popular focus areas that receive funding are Education, Human Services, and Philanthropy, Voluntarism & Grantmaking Foundations.

1. Education

2. Human Services

3. Philanthropy, Voluntarism & Grantmaking Foundations

Funding Over Time

How is funding for Brule County Grants for Nonprofits changing over time?

Funding has increased by 17.48%.

2022 $638,830,994

2023 $606,495,212
-5.06%

2024 $712,509,384
17.48%

South Dakota Counties That Receive the Most Funding

How does grant funding vary by county?

Minnehaha County, Lake County, and Pennington County receive the most funding.

County Total Grant Funding in 2024
Minnehaha County $176,653,145
Lake County $117,647,066
Pennington County $90,630,616
Brookings County $75,457,854
Todd County $56,559,538