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Best Large Grants for Nonprofit Organizations in California

Find the perfect Large Grants for Nonprofit Organizations in California on Instrumentl. 11,000+ Large Grants for Nonprofit Organizations in California in the United States.

11,000+

Available grants

$3.61B

Total funding

$5K

Median grant

11,000+ grants
$3.61B total
$5K median

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10,797 Results based on applied filters

AABCF Research Grants

American Association of Birth Centers Foundation (AABC)
Private
United States
Up to US $5,000
The AABCF Research Grants, offered by the American Association of Birth Centers Foundation, provide funding up to $5,000 for research projects focused on the birth center model of care. Open to individuals and organizations, these grants aim to enhance knowledge and practices in maternity and women's health care. Projects must demonstrate a clear plan and ability to complete the research on schedule, ensuring impactful contributions to the field.
Maternal And Perinatal Health

AES Seed Grants

American Epilepsy Society
Private
United States
Up to US $20,000
The American Epilepsy Society offers Seed Grants to support established researchers in exploring innovative research methodologies and collaborations. These grants aim to foster new lines of inquiry in epilepsy research. Notably, proposals that align with specific partner priorities may enjoy waived eligibility criteria, enhancing funding opportunities. This initiative seeks to advance understanding and treatment of epilepsy through novel research avenues.
Epilepsy

REI Cooperative Action Fund Grant

Rei Cooperative Action Fund
Private
United States
Unspecified amount
The REI Cooperative Action Fund Grant supports U.S.-based organizations that align with its mission to serve communities, particularly those connecting historically excluded individuals to the outdoors. The fund prioritizes initiatives that promote equitable access to outdoor spaces, enhance community health through nature, and create inclusive outdoor experiences. Eligible applicants must have a 501(c)(3) status and demonstrate a commitment to these values. However, individuals and certain organizations are not eligible for funding.
Outdoor Equity Outdoor Recreation Healthy Habits & Behaviors +1 more

OREF/Goldberg Arthritis Research Grant

Orthopaedic Research and Education Foundation
Private
United States
US $50,000
The OREF/Goldberg Arthritis Research Grant aims to support innovative research proposals focused on arthritis treatment, particularly arthroplasty. It seeks to foster new investigators by providing seed funding for projects that demonstrate clinical relevance and potential for practical application. Proposals must highlight their orthopaedic significance and aim to advance research that could lead to larger scale funding opportunities, enhancing the field of orthopaedics.
Arthritis

Houston Marathon Foundation Grant

Houston Marathon Foundation
Private
Houston County, Texas, United States
Unspecified amount
The Houston Marathon Foundation Grant supports running-related programs and initiatives, especially those that promote health and fitness in the greater Houston area. Organizations can submit unsolicited Letters of Inquiry, which must be pre-approved before submission. The Foundation prioritizes funding for programs that demonstrate fiscal responsibility and operational integrity, and applications are reviewed quarterly. Additionally, programs aiding elite athlete development outside Houston may also be considered.
Physical Fitness Sports & Athletics Parks & Public Spaces

AISES National Conference Travel Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
United States
Unspecified amount
The AISES National Conference Travel Scholarship provides financial support for full-time students in STEM fields to attend the annual conference. Covering registration, airfare, and lodging, recipients must commit to attending all events and uphold the AISES Code of Conduct. Selection is based on the quality of essays, letters of recommendation, and academic performance. Announcements for awarded scholarships will be made in late August/early September 2025, facilitating networking and professional development for indigenous students.
Academic Success & Enrichment STEM / STEAM Education Indigenous Services

Shubert Foundation: Arts Related Organizations Grants

The Shubert Foundation
Private
United States
Unspecified amount
The Shubert Foundation provides unrestricted grants to not-for-profit professional theatre and dance companies in the U.S. Its focus is on organizations with a proven track record in artistic and administrative excellence. Eligible applicants must have a minimum annual budget of $150,000 and demonstrate financial stability, strong community engagement, and the ability to generate income. The foundation does not fund individuals, project-specific requests, or organizations without 501(c)(3) status.
Theater Dance

We Are Moving The Needle Scholarship

We Are Moving The Needle
Association/Society
United States
Unspecified amount
The We Are Moving The Needle Scholarship supports women, trans, and non-binary creators in the music industry by offering two full scholarships for a masterclass with GRAMMY-nominated producer Alissia in Paris. This initiative aims to empower underrepresented voices through education and mentorship, fostering a more inclusive music industry. Participants will engage in hands-on workshops designed to enhance their production skills and gain insights from a leading industry professional, contributing to lasting cultural change.
Music LGBTQIA+ Services Academic Scholarship Programs

Trans Justice Funding Project Grants

Trans Justice Funding Project
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Trans Justice Funding Project (TJFP) provides grants to grassroots trans-led organizations in the U.S. and territories, focusing on those with budgets under $250,000. TJFP supports initiatives that address varying needs within trans communities, including health, legal aid, and mutual aid projects. The organization prioritizes groups led by trans people of color and emphasizes the importance of centering marginalized voices in the fight for trans justice.
Intersex & Transgender Rights

Towbes Foundation Grant

Towbes Foundation
Private
Santa Barbara County, California
US $1,000 - US $20,000
The Towbes Foundation, established in 1980, is dedicated to enhancing the Santa Barbara County community through strategic partnerships with local nonprofits. Focused on education and mental health, the foundation has awarded over $20 million to more than 400 organizations. It seeks to collaborate with 501(c)(3) organizations that target educational equity and direct mental health services, prioritizing programs that benefit underserved communities and utilize systematic evaluation processes to improve their impact.
Mental Health & Psychiatric Diseases Educational Access & Equity

Athene Charitable Foundation Grants

Athene Charitable Foundation
Private
United States
Unspecified amount
The Athene Charitable Foundation focuses on corporate social responsibility through community involvement, aiming to create positive social impacts in education, health, human services, and the environment. Their initiatives include partnerships, employee volunteering, and donations aligned with their mission. They prioritize organizations that support diversity and inclusion while ensuring compliance with their non-discrimination policies. Eligible entities must be registered 501(c)(3) organizations or equivalent, enhancing community welfare where Athene employees live and work.
Education Wellness & Healthy Living Human & Social Services +1 more

ADDF-Harrington Scholar Program

Alzheimers Drug Discovery Foundation
Private
Canada, United Kingdom +1 more
Up to US $600,000
The ADDF-Harrington Scholar Program aims to transform academic discoveries into effective treatments for Alzheimer’s disease and related dementias. With funding of up to $600,000 annually, this program prioritizes innovative drug targets and supports research from hit-to-lead optimization to IND-enabling studies. Eligible applicants include academic investigators with a strong potential to advance meaningful therapeutics. The program emphasizes collaboration with industry experts, making it a significant opportunity for advancing dementia research.
Dementia & Alzheimer’s Disease

The Fund for Homeless Women Grant

Community Foundation for Monterey County
Private
Monterey County, California
Up to US $50,000
The Fund for Homeless Women Grant aims to support programs and services for homeless women on the Monterey Peninsula, with a focus on emergency assistance and innovative housing solutions. Grants of up to $50,000 will address critical needs such as shelter, transportation, and personal care, while also promoting inter-agency collaborations. The initiative seeks to reduce the number of women in danger each night by enhancing access to safety and supportive services. Funding is available to 501(c)3 nonprofits and public agencies.
Supportive Housing & Shelters

PCRF: Translational Research Grant

Pediatric Cancer Research Foundation
Private
United States
Up to US $100,000
The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.
Pediatric Cancers

PCRF: Emerging Investigator Fellowship Grant

Pediatric Cancer Research Foundation
Private
United States
Up to US $75,000
The Pediatric Cancer Research Foundation (PCRF) offers the Emerging Investigator Fellowship Grant to support post-doctoral fellowships and clinical investigator training for promising pediatric cancer researchers. This grant aims to accelerate advancements in childhood cancer treatment by funding innovative research ideas. Applicants must have completed a minimum of two years in their fellowship or be within two years of their junior faculty role. This initiative fosters the next generation of researchers dedicated to combating childhood cancer.
Pediatric Cancers

PCRF: Donor Designated Grant Programs

Pediatric Cancer Research Foundation
Private
United States
Unspecified amount
The Pediatric Cancer Research Foundation (PCRF) offers Donor Designated Grant Programs aimed at funding innovative projects addressing childhood cancer. These grants support researchers dedicated to finding cures, enhancing treatment, and improving care. With an annual commitment to extraordinary researchers, PCRF ensures funds are directed towards promising advances in prevention and treatment. Since 1982, PCRF has raised over $51 million, significantly impacting survival rates and striving to eliminate childhood cancer through collaborative efforts and cutting-edge research.
Pediatric Cancers

American Epilepsy Society: Junior Investigator Research Awards

American Epilepsy Society
Private
United States
Up to US $75,000
The American Epilepsy Society's Junior Investigator Research Awards support early-career researchers in epilepsy. The awards, offering up to $50,000 for one year, aim to enhance the ability of new investigators to secure longer-term funding from sources like the NIH. Proposals are encouraged across a range of epilepsy research, including basic, translational, and clinical studies, as well as health services research. This initiative also includes complimentary membership to the AES Annual Meeting.
Epilepsy

Research Fellowship Awards

Crohns And Colitis Foundation Inc
Private
United States
Up to US $70,000
The Crohn’s & Colitis Foundation awards Research Fellowship Awards to support post-doctoral individuals pursuing innovative research in inflammatory bowel disease (IBD). With a maximum award of $70,000 per year for up to three years, the program encourages research aimed at understanding and preventing IBD progression. Eligible applicants must hold an MD or PhD and demonstrate relevant research experience. This initiative fosters the development of future independent researchers in the field of IBD.
Crohn’s Disease And Colitis

Elroy Webster Cooperative Studies (EWCS) Scholarships

Ralph K. Morris Foundation
Association/Society
United States
US $1,000 - US $2,500
The Elroy Webster Cooperative Studies Scholarships support graduate and law students in agricultural cooperative programs. Up to two EWCS Fellows can receive $2,500 each year, while up to three EWCS Scholars may receive $1,000. Applicants must demonstrate how their studies benefit the agricultural cooperative industry. The program promotes inclusivity, welcoming candidates without regard to race or background, and encourages attendance at related events to enhance networking and recognition.
Academic Scholarship Programs Agricultural Education Education - Higher Education

Research and Training Fellowships for Clinicians

American Epilepsy Society
Private
United States
Up to US $75,000
The American Epilepsy Society offers Research and Training Fellowships for Clinicians, providing up to $75,000 for one year to support clinical fellows or new faculty aiming to advance in epilepsy research. This fellowship encourages proposals across basic, translational, and clinical research. It also includes $1,000 for travel to the AES Annual Meeting, membership benefits, and complimentary registration, fostering collaboration and knowledge sharing in the epilepsy research community.
Epilepsy

Peyronie's Disease Fund

Healthwell Foundation
Private
United States
Up to US $5,600
The Peyronie's Disease Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from Peyronie's disease. This condition involves the formation of fibrous scar tissue in the penis, leading to painful erections and erectile dysfunction. The fund provides financial assistance for prescription drugs and related healthcare costs, ensuring that patients receive necessary treatment without the stress of high out-of-pocket expenses. HealthWell is committed to improving access to essential healthcare for America’s underinsured population.
Chronic Illnesses Health Care Access & Delivery Reproductive Health

Ross Wagner Foundation Scholarship

Ross Wagner Foundation
Private
Alameda County, California, Allegheny County, Pennsylvania +29 more
Up to US $100,000
The Ross Wagner Foundation Scholarship offers significant financial support for students pursuing degrees in various engineering fields, including civil, mechanical, and electrical engineering. With awards up to $25,000 annually, students can receive up to $100,000 over four years. Applicants must maintain a B average, work in engineering labs, and be enrolled in top-ranked engineering schools in the U.S. and Canada. This scholarship honors Ross Wagner's legacy, promoting excellence in engineering education.
Mechanical Engineering Civil Engineering Electrical Engineering +4 more

Stanley Fahn Junior Faculty Award

Parkinson's Foundation Inc.
Private
Canada, United States
US $300,000
The Stanley Fahn Junior Faculty Award, offered by the Parkinson's Foundation, supports early-career scientists in Parkinson's research. With $300,000 in funding over three years, it aims to bridge the gap for junior faculty transitioning to independent research. Eligible applicants must hold a PhD or MD and be U.S. or Canadian faculty members. This award promotes innovative research proposals that advance understanding and treatment of Parkinson's disease, fostering the next generation of scientists in this critical field.
Parkinson’s Disease

American Epilepsy Society: Postdoctoral Research Fellowships

American Epilepsy Society
Private
United States
Up to US $50,000
The American Epilepsy Society offers Postdoctoral Research Fellowships to support trainees conducting research on epilepsy's causes, treatment, and consequences. These fellowships provide up to $49,000 for stipend and benefits, $1,000 for travel to the AES annual meeting, and complimentary membership. Proposals can be basic, translational, or clinical research, and the number of awards depends on available funding.
Epilepsy

Parkinson Association of the Rockies Eric Wright Memorial Fund (UA2)

The Denver Foundation
Private
United States
Up to US $20,000
The Parkinson Association of the Rockies Eric Wright Memorial Fund honors Eric Wright's legacy by providing scholarships to high school seniors and college students affected by Parkinson Disease. Recipients, eligible for up to $20,000 over four years, are selected based on merit and financial need. This fund aims to inspire the next generation while supporting students who have experienced loss or hardship due to this condition, promoting education and resilience within the community.
Parkinson’s Disease

K–12 Educators Grants in American Music

American Musicological Society Inc
Private
United States
US $500
The K–12 Educators Grants in American Music, offered by the American Musicological Society, provides $500 awards to K-12 educators with an interest in American music to attend the Teaching Music History Conference. This grant supports educators in engaging with historical pedagogy through workshops and networking opportunities. Participants will explore American music's significance while developing actionable lesson plans, fostering connections among educators and researchers committed to enhancing music education.
Music Education - K through 12 Teacher Development & Training

Basic Field Grant

Legal Services Corporation
Private
American Samoa, District of Columbia +6 more
Approximately US $20,000
LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.
Minority Services Legal Services Native American Services

Large Grants for Nonprofit Organizations in California Highlights

Looking for large grants for nonprofit organizations in California?


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Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in California

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

400+ Large Grants for Nonprofit Organizations in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

200+ Large Grants for Nonprofit Organizations in California over $25K in average grant size

200+ Large Grants for Nonprofit Organizations in California over $50K in average grant size

38 Large Grants for Nonprofit Organizations in California supporting general operating expenses

300+ Large Grants for Nonprofit Organizations in California supporting programs / projects

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in California?

Most grants are due in the first quarter.

Q1
28.5%
Q2
25.8%
Q3
23.3%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in California?

Grants are most commonly $100,000.

$0 $0 Min.
$100,000 $100 K Median
$2,149,932 $2.1 M Average
$150,000,000 $150 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in California year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in California changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

Related Grants in California

Browse Other Nonprofit Operations & Capacity Grants in California

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