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Best Large Grants for Nonprofit Organizations in California

Find the perfect Large Grants for Nonprofit Organizations in California on Instrumentl. 11,000+ Large Grants for Nonprofit Organizations in California in the United States.

11,000+

Available grants

$3.61B

Total funding

$5K

Median grant

11,000+ grants
$3.61B total
$5K median

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10,803 Results based on applied filters

Ingebord Crede Memorial Scholarship Fund

Community Foundation for Palm Beach and Martin Counties
Private
United States
Unspecified amount

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Ingebord Crede Memorial Scholarship Fund

  • Student must major in secondary education, English literature or history
  • Demonstrate financial need
Education - Higher Education

Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.
Dental Health

Jason Debus Heigl Foundation Grant

Jason Debus Heigl Foundation
Private
United States
Unspecified amount
The Jason Debus Heigl Foundation Grant supports nonprofit organizations dedicated to animal welfare in the U.S. It aims to maximize the benefit to animals through education, spay and neuter initiatives, and positive advocacy. The foundation focuses on impactful programs, encouraging grants that align with their mission to end animal overpopulation and cruelty. Eligible applicants must be registered 501(c)(3) nonprofits, while individuals and political lobbying efforts are excluded from funding.
Animal Welfare - Domestic Animals & Pets

Milton Brown Express Grants

Santa Barbara Foundation
Private
Santa Barbara County, California
Up to US $1,000
The Milton Brown Express Grants, offered by the Santa Barbara Foundation, provide up to $1,000 annually to organizations enhancing senior citizens' welfare. Prioritizing small projects and short-term opportunities, these grants support a variety of impactful activities. Eligible applicants include 501(c)(3) organizations and public entities in Santa Barbara County, ensuring no discrimination in services. However, funds cannot be used for overhead, capital expenses, or individual support, fostering community development and enrichment.
Senior Services

NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) (356617)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) grant aims to facilitate high-quality conferences that align with public health and scientific missions. Key deadlines include December 12, 2024, April 12, 2025, and August 12, 2025, among others, specifically for AIDS-related applications. This funding opportunity is provided by the US Department of Health & Human Services: National Institutes of Health (NIH).
Epidemiology & Public Health

Cyberinfrastructure for Sustained Scientific Innovation (358751)

National Science Foundation (NSF)
Federal Government
United States
US $600,000 - US $5,000,000
The Cyberinfrastructure for Sustained Scientific Innovation (CSSI) program by the National Science Foundation aims to provide flexible funding opportunities to address evolving needs in cyberinfrastructure. It supports various award classes, including Elements for small groups, Framework Implementations for larger interdisciplinary teams, and Transition to Sustainability for established CI projects. These initiatives focus on developing integrated CI services, ensuring sustainable impact, and promoting collaboration across scientific disciplines to enhance research and innovation.
Cyberinfrastructure

NEESA Last Dollar Grant

United Negro College Fund Inc
Private
United States
Up to US $1,000

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

NEESA Last Dollar Grant

NEESA Last Dollar Grants are designed to provide need-based, last-dollar gap scholarships for graduating high school seniors facing barriers to college enrollment. Students may receive up to $1,000.00 for their freshman year attendance.

Education - Higher Education

L. George Pauze Scholarship

Grays Harbor Community Foundation
Private
United States
Unspecified amount

Grays Harbor Community Foundation

Established in 1994, Grays Harbor Community Foundation is a 501(c)(3) nonprofit that is known in our community for giving grants to other nonprofits in Grays Harbor County and for scholarships for Grays Harbor youth, but that is not our business.

Our real business is helping people, families, groups, and businesses be philanthropic or charitable. We provide the administrative and investment management services that make it easy for donors to be involved at whatever level they wish, and to accomplish their charitable goals with their tax deductible donations that improve the quality of life in Grays Harbor.

Scholarships

The Grays Harbor Community Foundation awards scholarships to local students for education after high school. The emphasis is on undergraduate studies at any two or four year college or university and vocational/technical programs leading to a license or certification.

Students submit only one application. When selected, the recipient is matched to the criteria of an individual scholarship by the scholarship review committee.

L. George Pauze Scholarship

The L. George Pauze Scholarship is new to the Community Foundation, but has been in existence since the 1970s. In January of 1970, Pauze announced the L. George Pauze Scholarship for a graduate of Hoquiam High School he had established with the help of his friends and attorneys, Omar Parker and George G. Wandel. Mr. Pauze came from Montreal to Grays Harbor in 1907. After years of hard work and ingenuity, he was able to maneuver himself into the ownership of a thriving lumber mill. George said: “You know, I didn’t have a chance to go to college, and I always missed it…I might have done even better if I’d had the opportunity to go. Actually, education is much more important now than in my day.” The law firm of Parker, Johnson, Parker (now Parker, Winkelman) has administered the Trust established that day, awarding at least one scholarship each year. The Gray Harbor Community Foundation is proud to now administer the scholarship to continue this tradition in perpetuity, and honor this “true gentleman.”

Education - Higher Education

Roxbury Volunteer Fire Department Memorial Scholarship

Connecticut Community Foundation
Private
United States
More than US $2,000
The Roxbury Volunteer Fire Department Memorial Scholarship, established by the Connecticut Community Foundation, supports college-bound students from Roxbury, offering a $2000 award. This scholarship prioritizes current or former members of the Roxbury Fire Department and their descendants, promoting educational opportunities for those committed to serving their community. With a legacy dating back to 1923, the Foundation plays a vital role in enhancing the educational landscape in the Greater Waterbury and Litchfield Hills region.
Academic Scholarship Programs

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Alex Shives Scholarship

Midlands Community Foundation
Private
United States
US $1,250 - US $2,500

About Us

Midlands Community Foundation (MCF) is here to serve and add value to donors’ philanthropic needs by providing them an opportunity to “invest in the power of community.” It is our goal to identify current and emerging issues, channel resources to address community needs, and help prepare for the future.

MCF Mission

The mission of Midlands Community Foundation is to be a catalyst for lasting impact in Sarpy and Cass counties and to give opportunities to organizations and individuals to pursue their charitable goals.

Scholarships Through MCF

Midlands Community Foundation is committed to the futures of communities in Sarpy and Cass Counties, and across the country. Supporting higher education of students is a direct investment in the futures of these communities.

Alex Shives Scholarship Application Guidelines

The purpose of the Fund is to distribute scholarships to assist qualified recipients in their pursuit of higher education who have graduated or will be a graduating senior from either Papillion LaVista or Papillion LaVista South High School and who have participated on the boys or girls golf team at either high school.

The Fund shall annually distribute one (1) scholarship in the total amount of $2,500, split evenly per semester (i.e., $1,250 Fall Semester, and $1,250 Spring Semester).

Education - Higher Education Golf

The Rona Jaffe Foundation Fellowship

Fine Arts Work Center in Provincetown
Private
United States
More than US $2,500
The Rona Jaffe Foundation Fellowship supports emerging women writers with a fully funded 7-month residency at the Fine Arts Work Center. Established by the Rona Jaffe Foundation, it includes a $2,500 prize to assist with travel and living expenses. Eligible candidates must be U.S. residents, at least 18 years old, and not enrolled in a degree program during the fellowship year. This prestigious fellowship aims to nurture exceptional literary talent.
Writing & Literature

Adoption Partnerships - Adoption Rewards & Adoption Event Grants

PetSmart Charities
Private
Canada, United States
Up to US $250,000
PetSmart Charities' Adoption Partnerships and Event Grants support organizations in finding loving homes for pets. With over 10 million pets placed, the program offers resources like cash rewards for adoptions and grants for event support. Eligible partners include registered charities and educational institutions. The maximum grant available is $5,000, aimed at maximizing the impact of adoption events. Join us in enhancing the lives of pets and their new families through collaboration and community engagement.
Animal Welfare - Domestic Animals & Pets

Natural Disaster Response Grants

PetSmart Charities
Private
Canada, United States
Unspecified amount
PetSmart Charities offers Natural Disaster Response Grants to support organizations addressing the urgent needs of pets affected by major disasters. Grant funds can be utilized for shelter supplies, veterinary care, structural repairs, and supplemental staff expenses within 30 to 45 days post-disaster. In special cases, funding may extend up to 60 days. Eligible applicants include authorized disaster responders and nonprofit organizations directly impacted by the disaster, ensuring timely assistance to affected animals and their caretakers.
Animal Welfare - Domestic Animals & Pets

El-Hibri Foundation Grant

El-Hibri Foundation
Private
United States
Unspecified amount
The El-Hibri Foundation Grant focuses on advancing the inclusion of American Muslim communities through nonprofit organizations. It supports initiatives that promote societal norms, enhance organizational capacity, and foster collaboration among diverse stakeholders. The Foundation encourages applications from 501(c)(3) organizations in the U.S. that align with its mission. While it does not accept unsolicited proposals, interested parties may pitch their projects for potential funding consideration.
Islam & Islamic Culture

John F. Burt Scholarship

Community Foundation of East Mississippi Inc.
Private
United States
US $1,000

This scholarship was established to honor the memory of John F. Burt of Neshoba County. Mr. Burt was raised during the depression and as a result he was resilient, a hard worker and resourceful. He learned the importance of sharing with those in need. He served in the US Navy during WWII where he strengthened his beliefs about patriotism, commitment and service. After the war, he and his wife opened a grocery store where he continued to be in service of others. God, family, and fellowship were priorities of Mr. Burt’s; he was always willing to be of service to anyone he considered family and at times to complete strangers. Obviously, Mr. Burt’s experiences shaped his moral code and guided the compass of his life.  Scholarship funds to be used towards fees for tuition and/or books only.

Education - Higher Education

Sons and Daughters Scholarship Program

Cleveland Cliffs Foundation
Private
Canada, United States
US $3,000
The Sons and Daughters Scholarship Program, administered by the Cleveland-Cliffs Foundation, offers a competitive scholarship of $3,000 annually for up to four years for undergraduate studies. This initiative recognizes exceptional academic and extracurricular achievements among high school students. Scholarships are available to those attending accredited colleges or universities in the U.S. or Canada, though children of Cleveland-Cliffs officers are ineligible. The program aims to enhance educational opportunities and support community growth.
Academic Scholarship Programs

BISSELL Pet Foundation: Partners for Pets

Bissell Pet Foundation
Private
United States
Unspecified amount
BISSELL Pet Foundation's Partners for Pets program supports over 6,025 animal welfare organizations across the U.S. by providing resources aimed at reducing homeless animals through adoption, spay/neuter initiatives, and emergency support. Eligible organizations must be 501(C)(3) nonprofits or local government entities engaged in animal welfare, fostering community connections and financial assistance during crises. This initiative not only benefits shelters but also enhances partnerships among various animal welfare groups, promoting a united effort to improve animal lives.
Animal Welfare - Domestic Animals & Pets

Persbacker Family Fund Scholarship

Connecticut Community Foundation
Private
United States
More than US $2,500
The Persbacker Family Fund Scholarship, established by the Connecticut Community Foundation, is dedicated to residents of Bridgewater who have volunteered significantly in their community for over six years. This scholarship aims to support local students in achieving their college education dreams. With awards starting at $2,500, the foundation continues its legacy of fostering educational opportunities for deserving students in the Greater Waterbury and Litchfield Hills region.
Academic Scholarship Programs

Ron Jones Memorial Scholarship

The Community Foundation for the Greater Capital Region
Private
United States
Unspecified amount

The Community Foundation for the Greater Capital Region

Empowering generous people with meaningful giving opportunities.

Since 1968, The Community Foundation for the Greater Capital Region (CFGCR) has been dedicated to improving the quality of life in the Greater Capital Region. We work with — and for — all our neighbors across the community because together, we are stronger.

Ron Jones Memorial Scholarship 

Established to honor the memory of beloved coach and teacher Ron Jones. This is not an athletic award, rather, it was established to recognize students who have demonstrated a devotion to the community of Hoosick Falls through compassion, action, respect and excellence.

Education - Higher Education

Carl J. Niedzial Memorial Scholarship

Connecticut Community Foundation
Private
United States
Unspecified amount
The Carl J. Niedzial Memorial Scholarship, established by the Connecticut Community Foundation in 1923, supports members of the CT State Police Credit Union and their immediate families, including grandchildren. As one of the largest scholarship providers in the Greater Waterbury and Litchfield Hills region, the foundation aims to help students achieve their college education dreams by addressing critical community issues and fostering equitable outcomes.
Academic Scholarship Programs

NCRG Large Grant

International Center for Responsible Gaming
Private
United States
Up to US $187,500
The NCRG Large Grant, provided by the International Center for Responsible Gaming, supports high-quality research on gambling disorders and responsible gambling. Eligible applicants can request up to $75,000 annually for a maximum of 24 months, totaling $187,500. The grant emphasizes scientific rigor through its advisory board, ensuring only the best proposals receive funding. This initiative aims to advance understanding and treatment of gambling-related issues through peer-reviewed research.
Addiction & Substance Use Disorders

ICRG Seed Grant

International Center for Responsible Gaming
Private
United States
Up to US $40,000
The ICRG Seed Grant supports innovative research aimed at understanding and treating gambling disorders. With a focus on pilot studies, secondary data analysis, and developing new methodologies, it encourages both established and early-career researchers to apply for funding up to $40,000. The grant emphasizes the importance of addressing critical issues in gambling research while ensuring the inclusion of diverse participant groups. This initiative aims to enhance public education and promote responsible gaming practices.
Addiction & Substance Use Disorders

Nestle Purina Animal Welfare Grants

Nestlé Purina
Corporate
Adams County, Colorado, Adams County, Pennsylvania +361 more
Unspecified amount
Nestlé Purina Animal Welfare Grants focus on enhancing the well-being of pets and their owners through monetary donations to 501(c)(3) tax-exempt pet welfare organizations in the U.S. These grants support capacity building, capital improvements, and spay/neuter funding. The program aims to strengthen relationships between pets and people, particularly in communities near Nestlé Purina facilities, ensuring that both pets and their owners thrive together.
Animal Welfare - Domestic Animals & Pets

Dr. Mable V. Jones Scholarship

United Negro College Fund Inc
Private
United States
US $4,250

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

Dr. Mable V. Jones Scholarship

The Dr. Mable V. Jones. Scholarship is a need-based OR merit-based scholarship for incoming freshmen who are enrolling at any accredited UNCF Member Institution or other accredited four-year HBCU.

Education - Higher Education

Michael L. Lomax Endowed Scholarship

United Negro College Fund Inc
Private
United States
Up to US $10,000

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

Michael L. Lomax Endowed Scholarship

The Michael L. Lomax Endowed Scholarship program was established by Tench and Simone Coxe in honor of Dr. Michael L. Lomax, President, and CEO of UNCF, in partnership with UNCF. The scholarship program is designed to provide scholarship support to deserving students attending one of the 37 UNCF member institutions.

Michael L. Lomax Endowed Scholarship program is annually renewable based on availability of funds and provided students continue to meet the eligibility requirement.

Education - Higher Education

HBCU Scholars Empowerment Program

United Negro College Fund Inc
Private
United States
Up to US $5,000

United Negro College Fund

“A mind is a terrible thing to waste.”®

For more than seven decades, this principle has remained at the heart of UNCF, enabling us to raise more than $5 billion and help more than 500,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 12,000 students scholarships, worth more than $65 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

HBCU Scholars Empowerment Program

The HBCU Scholars Empowerment Program is a renewable need-based scholarship open to students receiving four-year degrees at Predominantly Black Institutions (PBIs) and Historically Black Colleges and Universities (HBCUs).

Education - Higher Education

Large Grants for Nonprofit Organizations in California Highlights

Looking for large grants for nonprofit organizations in California?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in California recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in California

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

400+ Large Grants for Nonprofit Organizations in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

200+ Large Grants for Nonprofit Organizations in California over $25K in average grant size

200+ Large Grants for Nonprofit Organizations in California over $50K in average grant size

38 Large Grants for Nonprofit Organizations in California supporting general operating expenses

300+ Large Grants for Nonprofit Organizations in California supporting programs / projects

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in California?

Most grants are due in the first quarter.

Q1
28.5%
Q2
25.8%
Q3
23.3%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in California?

Grants are most commonly $100,000.

$0 $0 Min.
$100,000 $100 K Median
$2,149,932 $2.1 M Average
$150,000,000 $150 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in California year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in California changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

Related Grants in California

Browse Other Nonprofit Operations & Capacity Grants in California

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