Best Grants for Nonprofit Healthcare Programs in North Carolina

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

The Clancy & Theys 1949 Fund, managed by the Triangle Community Foundation, supports nonprofits in Central Florida, North Carolina, Upstate South Carolina, and Virginia. This donor-advised fund prioritizes initiatives in education, workforce development, youth programming, and community well-being, focusing on measurable impacts. The Foundation seeks to strengthen community ties and enhance quality of life by connecting donors with local organizations that address pressing needs. Both established partners and new applicants are encouraged to apply.

The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.

The Leon Levine Foundation, established in 1980, focuses on enhancing the human condition through investments in education, healthcare, and human services in North and South Carolina. The foundation seeks nonprofits with proven leadership and sustainable financial plans. They aim to create pathways to self-sufficiency and promote lasting change. LOIs are accepted year-round, and grant recipients must support an inclusive environment free from discrimination.

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

The Amgen Foundation Inc focuses on non-healthcare donations and sponsorships that target humanitarian, social, educational, and community programs. They offer support to organizations outside the U.S. healthcare community, particularly those recognized as tax-exempt public charities. Eligible organizations must serve specific Amgen communities throughout the U.S. This initiative aims to enhance health outcomes and address critical societal needs, thereby reducing the burden of disease and improving lives.

The Obici Healthcare Foundation offers Community Engagement Grants to support nonprofit initiatives that enhance the health of local residents. These one-time grants, ranging from $500 to $5000, are intended for programs that address community health needs, promote wellness, and improve health awareness. Applications are accepted on a rolling basis, and the Foundation prioritizes collaborative projects that innovate and sustain long-term health improvements in Virginia and North Carolina.

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The SECU Foundation Grant, offered by the State Employees Credit Union Foundation, focuses on supporting non-profits and governmental organizations that embody the philosophy of people helping people. The grant aims to promote community development through high-impact projects in housing, education, healthcare, and human services. Eligible projects should be tangible, have a statewide or major regional impact, and enhance the conditions for public employees in North Carolina. This initiative fosters collaboration and addresses critical community issues.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Duke Endowment's Child and Family Well-Being Grant provides implementation support to public and private agencies in North and South Carolina. This funding aims to adopt and sustain evidence-based programs that prevent and treat child maltreatment. Eligible organizations must have two years of audited financial statements and work with accredited groups. The grant prioritizes innovative solutions and advocacy to improve child welfare systems, ensuring effective support for children and families at risk.

The Philip L. Van Every Foundation provides grants to 501(c)(3) organizations in North and South Carolina, focusing on education, healthcare, human services, and the arts. With a commitment to strengthen communities and support fiscal responsibility, the foundation aims to enhance lives through meaningful projects. Organizations must demonstrate a track record of success to be eligible for funding, which is generally awarded for special projects and capital needs.

The Walnut Cove Members Association Grant provides funding to nonprofit organizations serving Western North Carolina. The grant focuses on social services, education, and cultural resources, with funding caps of $25K, $15K, and $10K respectively. Eligible applicants must be 501(c)(3) organizations sponsored by WCMA members. The award process is competitive, emphasizing measurable impact on local residents. Applications must adhere to specific guidelines, ensuring funds directly support community needs.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

The Georgia-Pacific Foundation Grant supports organizations in the Metro Atlanta area, focusing on education, entrepreneurship, community enrichment, and environmental sustainability. Established in 1958, the foundation prioritizes investments that align with its mission and values, promoting long-term well-being within communities where Georgia-Pacific operates. Eligible applicants include 501(c)(3) nonprofits, public schools, and local government entities located within 30 miles of GP manufacturing sites.

The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.

Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.

The Camber Foundation Grant supports community-driven initiatives in Eastern North Carolina, focusing on health, education, and economic development. It encourages nonprofits to apply for funding to enhance services without discrimination. Priorities include access to healthcare, mental health programs, and youth development. Eligible organizations must be 501(c)(3) entities based in the region, ensuring that all residents can thrive. The foundation aims to uplift communities through collaborative efforts and innovative solutions.

The Underdown Family Foundation, established in 1993, focuses on funding nonprofit organizations that enhance the Hickory, NC community. It prioritizes educational initiatives, health and human services, and faith-based projects, aiming to address local needs effectively. The foundation also supports research on significant diseases at a regional or national level. Organizations must be 501(c)(3) exempt and operate within Hickory to be eligible for funding.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Youth and Young Adult Well-Being Grant from the Nantahala Health Foundation aims to enhance the health and well-being of youth and young adults aged 5 to 24 in Western North Carolina. This initiative encourages partnerships with local organizations to address critical issues, such as mental health and educational support. Grant awards can be up to $100,000, focusing on innovative projects that foster resilience and improve health outcomes for underserved populations.