Best Large Grants for Nonprofit Organizations in Florida

The Rockefeller Family Fund's Climate Grant focuses on reducing fossil fuel production to combat climate change. It supports initiatives that hold polluters accountable and fosters citizen engagement for climate action. The fund prioritizes programs that seek to limit oil and gas production, enforce climate damages in court, and promote sustainable energy solutions. By addressing the fossil fuel industry's resistance, the grant aims to create meaningful progress towards climate goals and ensure that those responsible for climate disruption contribute to adaptation efforts.

The Junior Hamilton Memorial Baseball Scholarship, offered by the Community Foundation of North Central Washington, supports graduating seniors from Wenatchee, Eastmont, or Westside High Schools. Eligible applicants must maintain a minimum GPA of 2.85 and have participated in a high school baseball program for at least two years. This scholarship honors Junior Hamilton's legacy, empowering student-athletes and mariachi students to pursue higher education and achieve their dreams.

The MCTS Legacy Scholarship Program, established by the Mobile County Training School Alumni Association in collaboration with UNCF, offers ten $3,500 need-based scholarships for MCTS attendees or their descendants. This initiative aims to support educational pursuits among students connected to MCTS, enhancing access to higher education. Recipients will be notified within eight weeks after the application deadline, promoting academic success and community engagement. The program reflects UNCF's commitment to empowering minority students and fostering leadership.

The Steven K. Dentel AEESP Award for Global Outreach recognizes faculty excellence in environmental engineering outreach. This annual award honors individuals who significantly contribute to global community health through education, research, and mentorship. Recipients receive a $500 cash award and a plaque. Nominations from students are welcomed, and past nominations can be modified within three years. This award aims to highlight sustained leadership and service in the environmental engineering field.

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Civics Education Grant

The Civics Grant Program is designed to support projects and initiatives that promote a wider public understanding of democratic principles, the judicial system and the rule of law. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity), and other organizations to develop and support projects in their communities that foster public understanding of the rights and responsibilities of American citizenship, particularly among younger Americans.

Applicants may only receive one (1) Foundation grant per year.

The Stout Foundation Grant supports organizations aligned with the values of its founder, Mr. Stout. Grants are awarded exclusively to entities with 501(c)(3) tax-exempt status and focus on charitable, educational, and scientific purposes. Preference is given to organizations with low overhead costs and those located in areas frequented by Foundation members. The Foundation aims to promote effective use of funds while remaining flexible in its grant-making approach.

The NNLM Region 5 Professional Development Award offers funding for individuals at member institutions to enhance their knowledge and skills in health-related areas. This initiative aims to support meetings, workshops, and training that focus on health literacy, public health, and evidence-based practices. By fostering professional development, the NNLM seeks to improve healthcare services and access to health information across various communities, ultimately contributing to better public health outcomes.

The Eppley Foundation for Research, established in 1947, supports advanced scientific research in chemistry, physics, and biology. It prioritizes innovative studies, particularly in medical investigations and climate change. The foundation does not fund social sciences or projects with ample existing financial support. Applicants must hold a PhD or MD and be associated with a nonprofit in the US. The foundation aims to foster groundbreaking research that is unlikely to be replicated elsewhere.

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Senior Master Sergeant Texie C. Taylor, USAF Memorial Scholarship

Applicant must be a junior or senior undergraduate or graduate student majoring in physics, chemistry, biology, medicine, nursing (RN), engineering (aerospace, civil, chemical, electrical, mechanical) or mathematics with a minimum 3.0 GPA. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.

The Inspire Grants for Small Museums (2027) initiative, funded by the Institute of Museum and Library Services, aims to empower small museums across various disciplines. This program focuses on project-based funding to enhance public service through educational programs, exhibits, and community partnerships. By supporting small, often underfunded institutions, Inspire seeks to strengthen their capacity to engage communities and improve collections management, fostering experiential learning and discovery.

The Howard D. Colman Scholarship supports high school seniors from Boone and Winnebago Counties pursuing degrees in engineering or technology fields. Established in memory of entrepreneur Howard D. Colman, the scholarship offers $2,500 in the first year, with potential renewal up to $10,000 for three additional years, contingent on meeting criteria. Recipients gain hands-on experience through internships with local firms, fostering connections to the Rockford area.

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience for rising college juniors and seniors designed to empower the next generation of scientific leaders through mentorship, hands-on research, and community. 

The Cech Fellows Program gives undergraduate students in the life sciences the opportunity to conduct hands-on research with leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s Janelia Research Campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health. 

This immersive program gives students the chance to contribute to real scientific discovery, receive professional mentorship, explore potential careers in biological and biomedical research, and connect with a community of like-minded peers.  

Gain Hands-On Experience in Research & Lab Work

The HHMI Cech Fellows Program is a 9-week, full-time, immersive research experience running from June 14, 2027 to August 12, 2027. Fellows: 

• conduct cutting-edge basic research in an HHMI lab for their own educational benefit  
• participate in professional development workshops   
• engage with a vibrant scientific community  
• build essential skills for future success in a scientific career   

Funding & Logistics 

As a Cech Fellow, students:  

• receive a $15,000 stipend if placed in an HHMI lab at a host institution, intended to cover travel, housing, meals, and incidentals. (Students are responsible for arranging their own housing.) 
• receive a $12,000 stipend if placed at HHMI’s Janelia Research Campus. (Students placed at Janelia have access to free, on-campus housing.)
• participate in an end-of-summer symposium at the Janelia Research Campus in Ashburn, VA, from August 10–12, 2027, at which they present their research and meet other Cech Fellows from across the country. Food, lodging, and travel to and from the symposium are provided by HHMI. 
• are matched with a local contact from their host lab who will provide suggestions for local housing options. Students are expected to travel to arrive at their host institutions by June 14, 2027.  

The Thad G. Gayman Memorial Scholarship Fund honors Thad Gayman, a dedicated automotive technician and Northern York High School alumnus who tragically passed away at age 23. Established to support students in automotive technology, this fund emphasizes academic achievement, financial need, and a commitment to the field. Extra consideration is given to graduates from Northern York High School. This one-time scholarship aims to empower future automotive professionals in honor of Thad's legacy.

The GCCF Community Grants, offered by Gulf Coast Community Foundation, aim to enhance community well-being through strategic partnerships with nonprofit organizations. With a focus on health, education, and cultural development, these grants support 501(c)(3) organizations that benefit residents in Sarasota, Charlotte, and Boca Grande. Grant requests are accepted on a rolling basis, ensuring timely support for impactful projects. Individual schools and booster clubs are not eligible for funding, as the foundation prioritizes broader community initiatives.

The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.

The SHAPE America: Joy of Effort Award recognizes dedicated individuals who exemplify the spirit of commitment and passion in health and physical education. Awardees are current SHAPE America members with at least three years of membership, demonstrating excellence in teaching, coaching, or leadership. This prestigious award celebrates those who have made significant contributions to the field, inspiring others to lead healthy, active lives through their efforts in education and advocacy.

Alliance for Social Trust: Trust in Practice Awards

Trust is the foundation of vibrant, resilient communities and healthy civic life. Across the country, local and national organizations are demonstrating the profound ways trust shapes our collective well-being—strengthening relationships between neighbors, cultivating confidence in institutions, and enabling people to work together to solve shared challenges. These efforts are often rooted in the knowledge and leadership of those closest to the work. 

The Trust in Practice Awards support non-profit organizations that are collaborating on new initiatives to build trust across local or virtual communities. Grantees will be part of a national network dedicated to fostering trust through the Alliance for Social Trust’s programs and storytelling platforms. Award recipients will also participate in the annual Trust in Practice Summit to celebrate the work of trust builders.

The Ida B. Wells Graduate Student Fellowship, offered by the Coordinating Council for Women in History, provides a $1000 award to graduate students working on dissertations that explore themes of race and gender. This fellowship supports crucial stages of research or writing for students across various disciplines, not limited to history departments. It aims to foster inclusive scholarship and advance the representation of women in historical studies, encouraging emerging scholars to engage with these vital topics.

The Community Development Block Grant Program for Indian Tribes and Alaska Native Villages aims to foster viable communities by providing funding for decent housing, suitable living environments, and economic opportunities for low- and moderate-income individuals. Notably, the program also includes Imminent Threat Grants to address urgent public health or safety issues. These competitive grants are essential for enhancing community welfare and addressing immediate challenges faced by tribal residents.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Lambeth Family Scholarship

This scholarship, designed to honor and financially support students pursuing a degree in engineering, natural sciences, mathematics, computer science or business, supports high school seniors in Washington State who will study at a public university, community college or technical school. This scholarship varies from $1,000 to $3,000 and is renewable for up to 4 years.

The Friends of the South Manatee Library Scholarship Fund, established by the Manatee Community Foundation, provides annual scholarships for students pursuing a master's degree in library science. This initiative also supports South Manatee Branch Library staff through grants for professional development. With over 25 years of commitment, the Foundation fosters philanthropy and community enhancement, ensuring that both citizens and libraries thrive through education and service.

The Zera Foundation Grant, established in 2011, supports nonprofit organizations in Oregon aimed at enhancing quality of life. With a focus on poverty, youth, animals, and Jewish-based initiatives, the Foundation seeks to fund new programs that help existing organizations achieve their mission. Eligible applicants must be 501(c)(3) tax-exempt entities and can only receive one grant per year, ensuring a concentrated impact in their communities.

The Cold Noses Foundation Grant aims to support organizations dedicated to the humane treatment of animals, including domestic pets, wildlife, and farm animals. Grants are available to U.S. non-profits and selected international equivalents with an annual income of $200,000 or less. The foundation emphasizes accountability, requiring detailed financial reporting and adherence to ethical standards. Deadlines for applications vary by region, ensuring timely funding for impactful animal welfare projects.

About Us

Our Mission

The Marfan Foundation drives research, education and support – and builds community – to improve outcomes, save lives and empower all people to thrive who are living with Marfan, Loeys-Dietz, Vascular Ehlers-Danlos syndromes, and related genetic aortic and vascular conditions.

Our Vision

Quality of life, longevity, and cures for all people with genetic aortic and vascular conditions.

Innovators Award

This is for faculty investigators for $100,000 over 2 years ($50,000 per year), to explore an innovative concept in “translational” science that has applicability to improving human health. Examples could include fundamental research, diagnostic tests, biomarkers, biomedical engineering advances, and imaging advances. Collection of data for improved evidence-based medical guidance are of great interest.

The IMPACT 100 Pensacola Bay Area Grant awards at least $100,000 to nonprofit organizations in five focus areas: Arts, Education, Environment, Family, and Health. Funded by member contributions, the grants aim to create significant community impact, with eligibility for tax-exempt organizations based in Escambia or Santa Rosa counties. The application process emphasizes new initiatives and collaboration among nonprofits. Membership donations are collected annually, and grants must be used within 24 months.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

The Guido's Fresh Marketplace Scholarship Fund, established by the Berkshire Taconic Community Foundation, honors the legacy of Guido Masiero, a dedicated educator and entrepreneur. This scholarship aims to support graduating high school students from public schools in Pittsfield, Lenox, or Great Barrington, Massachusetts, who are pursuing higher education in physical education, health, wellness, or business studies. The fund reflects the foundation's mission to enhance community opportunities and economic mobility.