Best Greene County Grants for Nonprofits in North Carolina

The FY26 Amyotrophic Lateral Sclerosis Research Program's Pilot Clinical Trial Award aims to accelerate clinical trials that can significantly impact ALS treatment and management. Focus areas include biomarker-driven interventions and improvements in clinical care. Trials must begin within 12 months of the award and incorporate community collaboration and a detailed regulatory strategy. This award emphasizes the importance of therapeutic interventions and a transition plan for advancing study outcomes beyond the funded work.

The FY26 Amyotrophic Lateral Sclerosis Research Program (ALSRP) Clinical Outcomes and Biomarkers Award (COBA) aims to enhance clinical trials for ALS by developing and validating clinical outcomes and biomarkers. This funding opportunity encourages innovative projects that may focus on specific therapies, ALS subtypes, or digital health measures. Collaboration with the ALS community is essential to ensure that research is relevant and informed by lived experiences.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 4 supports innovative research with the potential for significant breakthroughs in breast cancer. Applications must address key BCRP challenges or justify exceptions, focusing on impactful solutions. This program mandates clinical trials and requires participation from breast cancer consumer advocates. The funding supports single or partnered Principal Investigators, ensuring comprehensive submission processes to avoid administrative withdrawal.

The DoW Ovarian Cancer Academy Early-Career Investigator Award supports junior faculty in conducting innovative ovarian cancer research. Established in FY09, this unique virtual academy fosters mentorship, collaboration, and networking among Early-Career Investigators (ECIs) and their mentors. Participants engage in monthly webinars and annual workshops, enhancing their research skills while contributing to impactful studies in ovarian cancer. The program aims to cultivate a new generation of highly productive researchers in this critical field.

The Ovarian Cancer Clinical Trial Academy (OCCTA) supports Early-Career Investigators (ECIs) in clinical trial research aimed at effective ovarian cancer treatments. It provides essential mentoring, networking, and skill development needed for executing clinical trials. The FY26 funding will specifically support translational research and early-phase trials, requiring preliminary data and a commitment of at least 25% effort from the ECI. Mentorship is vital, with a focus on experienced clinical trialists guiding ECIs.

The DoW Ovarian Cancer Clinical Trial Award, funded by the U.S. Army Medical Command, aims to accelerate the implementation of clinical trials that significantly impact ovarian cancer treatment. This award supports diverse trial designs, from early proof-of-concept studies to large-scale efficacy trials, evaluating innovative drugs, biologics, and technologies. By fostering research in this critical area, the program seeks to enhance patient outcomes and advance the understanding of ovarian cancer management.

The FY26 Breast Cancer Research Program (BCRP) Breakthrough Award Level 3 supports transformative research aimed at significant advancements in breast cancer treatment. Applicants must address key challenges outlined by the program, ensuring their proposals demonstrate potential for impactful breakthroughs. This funding mechanism, which permits small-scale clinical trials, emphasizes collaboration by requiring research teams to include two breast cancer consumer advocates and allows for a single Principal Investigator or two partnering PIs.

The Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award aims to support impactful research addressing critical needs in ovarian cancer and patient care. It requires a robust research plan with preliminary data and allows for studies across all research phases, excluding clinical trials. A unique Partnering Principal Investigator option encourages collaboration between two PIs to enhance research outcomes beyond individual efforts, promoting innovation in the field of ovarian cancer.

The DoW Ovarian Cancer Pilot Award fosters innovative research that challenges existing paradigms in ovarian cancer. It aims to propel groundbreaking discoveries and advancements in the field. Notably, the award prioritizes originality over scientific merit alone, ensuring that innovative ideas are at the forefront. The application process includes a blinded pre-application screening to maintain confidentiality and integrity, encouraging fresh perspectives in ovarian cancer research.

The FY26 Breast Cancer Research Program's Transformative Breast Cancer Consortium Award fosters significant collaborations that aim to revolutionize care for individuals affected by breast cancer. This award supports a multidisciplinary consortium of leading scientists, clinicians, and advocates to tackle major challenges in breast cancer research. Proposals must address at least one of the program's overarching challenges and demonstrate a transformative impact that cannot be achieved by individual investigators alone.

The FY26 Hearing Restoration Research Program (HRRP) Focused Research Award (FRA) aims to enhance drug discovery and therapeutic development for hearing restoration following military-related auditory injuries. The award supports preclinical and clinical studies aligned with HRRP focus areas. It features two funding levels, including a Partnering Principal Investigator option, and evaluates proposals based on research rationale, strategy, impact, and personnel. Notably, it excludes funding for clinical trials, tinnitus, and vestibular research.

Geological Society of America 

The Geological Society of America (GSA), founded in 1888, is a global scientific society with members from academia, government, and industry in more than 100 countries. Through its meetings, publications, and programs, GSA enhances the professional growth of geoscientists at all career levels, encourages cooperative research among earth, life, planetary, and social scientists, fosters public dialogue on geoscience issues, and promotes the geosciences in the service of humankind. GSA is headquartered in Boulder, Colorado, USA.

Jack Kleinman Memorial Award for Volcano Research

The Jack Kleinman Memorial Award for Volcano Research represents a partnership between GSA and the U.S. Geological Survey (USGS) to recognize early-career scientists conducting high-impact research in volcanology. The award was created in memory of Jack Kleinman—a USGS Cascades Volcano Observatory scientist known for his commitment to collecting high-quality field data and who relished a challenge, inspired enthusiasm in others, and delighted in the natural world. The award honors students who demonstrate these same qualities in their scientific explorations.

Up to US$5,000 may be awarded to undergraduate, graduate, and aspiring graduate students, regardless of current enrollment status. Successful proposals typically focus on geologic, geochemical, geophysical, or hazards investigations with an emphasis on fieldwork. Cooperation with a staff member from the USGS Volcano Science Center is encouraged and given considerable weight in the selection process.

Funding is intended to defray the costs of field-focused studies, such as travel to field sites, living expenses during fieldwork, field supplies, and analytical costs. Awardees are invited to present their results in the USGS Kleinman Seminar Series and attend the Awards Ceremony at the GSA annual meeting.

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 1: Research Capacity Building

Up to two (2) projects will be selected, each receiving up to $100,000 over two (2) years.

Build capacity within the organization, institution, and/or clinical care setting to conduct research on healthcare approaches to addressing firearm violence or firearm suicide.

Investing in research and healthcare to prevent, treat, and heal firearm-related harms

Kaiser Permanente Center for Gun Violence Research and Education

Kaiser Permanente established this Center in 2022 to scale its longstanding commitment to help communities prevent, treat, and heal from firearm-related injuries or death. The Center’s focus on violence prevention is rooted in healthcare, care delivery, and clinical interventions.

The Center is coordinated in collaboration with the Health Alliance for Violence Intervention (HAVI).

Research to support more effective health interventions

The Center funds research to test and expand health interventions that treat and prevent firearm injuries and deaths. This approach uses the same rigor and expertise that has helped treat and prevent other leading health concerns and causes of death, such as stroke, cancer, and heart disease. Funding supports projects to:

• Identify and evaluate health system strategies to address firearm injury and death, especially in communities that are most impacted.
• Test clinical interventions to prevent, treat, and heal trauma caused by firearm injuries and death.
• Assess pathways to implement and scale clinical interventions for firearm injury prevention in various healthcare settings.
• Improve healthcare identification and engagement of individuals at high risk of firearm injury or death.

Since its inception, the Center has awarded more than $8.5 million through 49 grants across 25 states and Washington, D.C., to advance research, capacity building, narrative change, and education.

Funding Opportunity

The call is open to applicants at varying stages of the research continuum. It is expected that central to all proposed initiatives are efforts to meaningfully engage communities that have been the most impacted by firearm violence.

What Work Will Be Considered for Funding?

Funding is currently available in two categories: Category 1 - Research Capacity Building; Category 2 - Pilot or Formative Healthcare Research

Category 2 - Pilot or Formative Healthcare Research

Up to two (2) projects will be selected, each receiving up to $250,000 over two (2) years.

Expand or pilot new research on evidence-informed healthcare practice or clinical care models that address firearm violence or firearm suicide.

About The Children’s Heart Foundation

The Children’s Heart Foundation (CHF) is the country’s leading national organization solely dedicated to funding congenital heart defect (CHD) research. The mission of The Children’s Heart Foundation is to fund the most promising research to advance the diagnosis, treatment, and prevention of congenital heart defects. Since its inception, CHF has funded millions of dollars of CHD research across the U.S. and Canada. 

AHA/CHF Congenital Heart Defect Research Awards

The Children’s Heart Foundation partners with the American Heart Association to fund Congenital Heart Defect Research Awards. This collaborative investment of funds provides support for investigators who are actively conducting research directly related to advancing the prevention, diagnosis, and treatment of CHDs, which directly aligns with The Children's Heart Foundation's mission. 

Congenital Heart Defect Funding Opportunities

A multi-year commitment between the American Heart Association (AHA) and Children’s Heart Foundation (CHF) jointly supports Predoctoral Fellowship or Postdoctoral Fellowship investigators actively conducting basic, clinical, population, or translational congenital heart defects research.

Postdoctoral Fellowship

Purpose

To enhance the training of postdoctoral applicants who are not yet independent. The applicant must be embedded in an appropriate investigative group with the mentorship, support, and relevant scientific guidance of a research mentor. Recognizing the unique challenges that clinicians, in particular, experience in balancing research and clinical activity, this award mechanism aims to be as flexible as possible to enable applicants to develop academic careers in research alongside fulfilling clinical service commitments.

The trainee and mentor should collaboratively provide a thoughtfully planned, systematic proposal aimed at clearly answering an investigative question in cardiovascular, cerebrovascular or brain health research

• AHA research awards are limited to U.S.-based non-profit institutions, including medical, osteopathic, and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals andothers that can demonstrate the ability to conduct the proposed research.

• Applicants must be AHA Professional Members at the time of proposal submission. The AHA expects all mentors associated with training/mentored research awards to maintain active AHA membership, as well.

• This award is not intended for individuals of faculty rank.

Applicants are not required to reside in the United States for any period before applying for American Heart Association funding. However, applicants must have one of the following designations at the time of proposal submission – not award start date, depending on career stage and each individual’s situation. An awardee must maintain one of the designations listed below throughout the duration of the award. Please consult with your institution’s grant officer.

• U.S. citizen
• Permanent resident
• Pending permanent resident (must have filed Form I-485 for permanent resident status and obtained an I-797C 3 Notice of Action that the application has been received by USCIS and case is pending)
• E-3 Visa - specialty occupation worker
• F-1 Visa – student (for predoctoral and postdoctoral fellows only)
• G-4 Visa - family member of an international organization employee
• H1-B Visa - temporary worker in a specialty occupation
• J-1 Visa - exchange visitor (pre- and postdoctoral fellowships only; all other awardees must obtain an H-1B or equivalent by the award activation date)
• O-1 Visa - temporary worker with extraordinary abilities in the sciences
• TN Visa - NAFTA Professional
• DACA - Deferred Action for Childhood Arrivals

The FY26 Peer Reviewed Cancer Research Program's Idea Award promotes innovative, high-risk cancer research initiatives. It supports groundbreaking concepts that advance cancer knowledge, patient care, and treatment options within the Military Health System. Projects must demonstrate creativity and innovation, avoiding incremental advancements. Notably, the Early Career Investigator Option is available to foster the growth of promising new investigators early in their careers. This award aims to make significant contributions to cancer research for Service Members and Veterans.

The DoW Peer Reviewed Cancer Clinical Trial Award supports the rapid initiation of clinical trials aimed at significantly improving cancer treatment. Projects may range from small pilot studies to large-scale phase III trials, focusing on innovative products, drugs, or devices. This award mandates the inclusion of patient advocates and prohibits animal studies, ensuring that all preclinical work is completed prior to the award start date. Regulatory applications must be submitted if required for the proposed trials.

The FY26 Peer Reviewed Cancer Research Program Impact Award promotes significant research aimed at enhancing clinical cancer care. It requires preliminary data to ensure feasibility and emphasizes projects with a strong potential for immediate impact. This funding supports clinical trials and allows for either a single Principal Investigator or a duo of partnering PIs, ensuring that both can contribute distinct aspects of the research. Applications must be carefully coordinated to avoid withdrawal risks.

The FY26 Traumatic Brain Injury and Psychological Health Research Program's Clinical Trial Award aims to fund impactful clinical trials that address psychological health issues and traumatic brain injury (TBI). This award supports a variety of interventions, requires preliminary data, and mandates community-based participatory research approaches. It offers two research levels: one for pilot studies and early trials, and another for larger, advanced trials assessing effectiveness in relevant populations.

The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.

The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.

The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

The DoW Traumatic Brain Injury and Psychological Health Translational Research Award aims to transform scientific discoveries into clinical applications. This program encourages innovative research approaches and requires preliminary data. It prohibits basic research and clinical trials, emphasizing the need for relevant animal models or community-based participatory research for human subjects. Funding supports two research levels, refining ideas into tangible products or evaluating them for clinical trials, with options for early-career investigator partnerships.

Information for Russell Sage Foundation Grant Seekers

RSF makes external grants for social science research projects that address questions of interest under its research priorities. 

Research Priorities

RSF supports high-quality innovative research under four core research priorities:

• Behavioral Science and Decision Making in Context
• Future of Work
• Race, Ethnicity, and Immigration
• Social, Political, and Economic Inequality

In addition, it supports research under the following time-limited co-funded research priorities:

• Immigration and Immigrant Integration
• Implications of the 2023 Supreme Court Decision to Ban Race-Conscious Admissions at Colleges and Universities for Educational Attainment and Economic Mobility
• Causal Research on the Criminal Justice System

Overview of Core Research Grants

All research grant applications must be preceded by a letter of inquiry (LOI). RSF has 3 funding cycles per year and only considers proposals that are invited following review of an initial letter of inquiry. After peer review, about 15% of those who submit an LOI will receive an invitation to submit a full proposal. RSF rarely considers projects for which the investigators have not already fully-developed the research design, the sample framework, access to data, etc. Investigators are encouraged to submit an LOI after they have developed and pre-tested survey instruments, completed preliminary data analyses if the data are publically-available or conducted some preliminary interviews for qualitative studies.

Funding

There are two levels of funding for core grants, Trustee-approved grants and Presidential-Authority grants. The maximum grant amount for a Trustee grant is $200,000, including 15% indirect costs. Grants up to $75,000 are considered Presidential-Authority grants. RSF has 3 funding cycles per year and only considers proposals that are invited following review of an initial letter of inquiry. After peer review, about 15% of those who submit an LOI will receive an invitation to submit a full proposal. The final funding rate for core research grants is approximately 6-10% of submitted LOIs.

Implications of the 2023 Supreme Court Decision to Ban Race-Conscious Admissions at Colleges and Universities for Educational Attainment and Economic Mobility - Request for Proposals

The Russell Sage Foundation, in collaboration with the Hewlett, Spencer, and William T. Grant foundations, seeks to support innovative research on the effects of the Supreme Court decision on a diversity of outcomes—from who attends college and where and the extent to which alternatives to race-conscious policies contribute to educational attainment and economic mobility among different groups in the population. Our interests extend beyond the effects on applications, admissions, enrollment, and degree completion and include the downstream effects, including whether and how the decision alters the college-to-career pipeline that many employers rely on to diversify their workforce, and the factors associated with public opposition to and support for race-conscious policies. We are particularly interested in analyses that make use of newly available data or demonstrate novel uses of existing data. We also support original data collection and encourage methodological variety and inter-disciplinary collaboration. 

Read the full RFP for this time-limited co-funded research priority here.

Joyful Heart Foundation

Since 2004, Joyful Heart has been a leading national organization with a mission to transform society’s response to sexual assault, domestic violence and child abuse by building a world that prioritizes survivors’ healing.

Our Areas of Focus

We continue to carry out our mission through programming centered on survivors’ needs. We strive to fill gaps where those needs aren’t being met, without duplicating existing programs. In order to build a more compassionate, more informed culture rooted in the possibility and promise of healing, we focus on three key areas: Awareness and Community Building, Policy and Advocacy and Healing Programs.

• Healing Programs and Resources: Creating and fostering a culture of healing and nurturing for survivors and the professionals who support them.
• Policy and Advocacy: Advocating for policies and practices that forge a path to safety, justice and hope for survivors.

• Awareness and Community Building: Creating spaces and conversations that channel a drive for change into action and transformation.

Heal the Healers Grant 

Helping alleviate the effects of secondary trauma for the long-term wellbeing of professionals who support survivors

Building for a System of Care and Compassion

Heal the Healers Grantmaking Program provides critical support for professionals who help survivors heal and seek justice. People working on the frontlines of survivor-centered services are subject to the often overlooked effects of secondary trauma that can emerge as a result of continuous exposure to people who have recently experienced abuse and violence.

The Heal the Healers Grant Fund and Grantee Learning Cohorts provide resources to mitigate the effects of secondary trauma among the practitioners responsible for the earliest stages of survivors’ paths to justice and healing. Creating a safer, more compassionate world for the people who do this work helps lay a foundation for lasting change and a world where every survivor’s healing is prioritized.

The Heal the Healers Fund provides micro-grants of up to $5,000 to nonprofit, Tribal, or governmental organizations supporting survivors for training, small capital projects, or organizational activities.

Areas of Support

The Joyful Heart Foundation has established the following guidelines for its Heal the Healers Fund grants to support those working directly with survivors in the following areas.

• Training and/or program development on self-care practices such as training in trauma-informed yoga, breathwork, somatic therapy, etc.
• Small capital items and equipment that specifically allow staff and volunteers to address their self care needs such as daylight lamps for staff or new furniture for a break room.
• Staff activities to build and support connections between colleagues such as, trust building experiences, monthly pizza nights, or bagel Fridays.
• Or any combination of the above. 

In addition to the financial support, grantees will also be invited to join a peer learning community cohort that includes:

• Opportunities to amplify their fellowship/cohort experiences to inspire others in the field
• Virtual peer-to-peer networking opportunities
• Virtual training/presentations by leading healers, therapists and other professionals with expertise in cutting edge vicarious trauma, empowerment, leadership and therapeutic modalities

Target Foundation

At Target Foundation, we envision a world where all families and communities have the resources they need to determine and realize their own joy in life. It’s a reality that is out of reach for far too many families as they struggle for access to economic opportunity, financial stability and the kind of empowerment that lifts up their communities. We believe we have a responsibility to work to remove barriers and to help create that access, resulting in a world where all families can thrive.

Community Engagement Funds

Community Engagement Funds (CEF) is a community grant program that empowers Target stores and distribution center leaders to make meaningful, localized giving decisions that meet the needs of the communities where our team members and guests live, work, and thrive.

• Organizations cannot apply for the same program in both grant cycles.
• Organizations are encouraged to apply during the cycle that best aligns with their program timing.
• A maximum of 10 applications is allowed per organization at any time.

CEF will prioritize nonprofit programs and initiatives aligned to its focus areas:

• Thriving Families; Basic needs and youth development..
• Vibrant Neighborhoods: Community vitalization; Community and green spaces.
• Emerging Creative & Culture: Cultural partnerships and creative programming.
• Economic Opportunity: Workforce development.