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Best Hamilton County Grants for Nonprofits in Ohio

Discover active funding opportunities in Hamilton County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Marion, Madison, and Boone.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,453 Results based on applied filters

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.
Biomedical informatics Neurological Diseases & Disorders Musculoskeletal Diseases

Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) (356887)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Limited Competition: Basic Instrumentation Grant (BIG) Program offers funding to NIH-supported researchers for purchasing specialized instruments or integrated systems, with minimum awards of $25,000 and maximum awards reaching $350,000. Eligibility is restricted to institutions that have not received significant S10 funding in recent years. This program aims to enhance research capabilities by providing access to essential technology, thereby fostering scientific innovation and collaboration within the NIH community.
Biology Health & Medicine Medical Technology, Devices, and Equipment

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (356886)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Shared Instrumentation Grant (SIG) Program supports NIH-funded investigators in acquiring high-cost, specialized instruments, with a minimum award of $50,000 and a maximum of $750,000. Eligible instruments include light microscopes, mass spectrometers, and DNA sequencers, among others. This program aims to enhance research capabilities by enabling the purchase or upgrade of essential equipment for scientific advancement.
Biology Health & Medicine Medical Technology, Devices, and Equipment

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) (356883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The High-End Instrumentation (HEI) Grant Program, offered by the NIH, invites applications for purchasing or upgrading high-end, specialized instruments, with a minimum award of $750,001 and a maximum of $2,000,000. This program supports NIH investigators aiming to enhance their research capabilities through advanced technologies such as mass spectrometers and electron microscopes. Applications must be submitted by 5:00 pm local time of the applicant organization.
Medical Technology, Devices, and Equipment Health & Medicine Biotechnology +1 more

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) (356888)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.
Biomedical informatics Epidemiology & Public Health Health Information Technology

Ohio Transit Partnership Program

Ohio Department of Transportation
State/Local Government
Ohio
Unspecified amount
The Ohio Transit Partnership Program (OTP2) provides essential financial support to urban and rural public transit systems in Ohio, aiming to optimize state and federal funding utilization. It serves public transit agencies receiving FTA Section 5307 and 5311 funds, facilitating capital and operational projects. OTP2 prioritizes Tier I projects focused on preservation while also supporting innovative Tier II projects to enhance transit capabilities. This program ultimately strengthens Ohio's public transportation infrastructure.
Public Transportation & Mass Transit Systems

Reboot Representation Grant

Reboot Representation Tech Coalition
Association/Society
United States
Unspecified amount
The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.
Computer Science & Engineering Diversity, Equity & Inclusion Women's Rights & Equality +4 more

JobsOhio: Small Business Grant

JobsOhio
Private
Ohio
Up to US $50,000
The JobsOhio Small Business Grant provides essential financial support to qualified businesses in designated communities and those owned by eligible populations. With funding capped at $8 million annually, businesses can receive up to $50,000 to help them grow. This program focuses on small to medium-sized companies, especially those facing unique challenges, and aims to foster job creation and investment in areas that are often overlooked by larger corporate investments.
Job Creation Business Development

OEPA: Source Reduction Grants

Ohio Environmental Protection Agency
State/Local Government
Ohio
Up to US $10,000
The OEPA: Source Reduction Grants program provides financial assistance to governments, non-profits, and educational institutions for purchasing equipment that promotes reuse practices. Eligible items include water bottle refilling stations and dishwashers. However, costs for installation and maintenance are not covered by the grant. This initiative aims to support sustainable practices in communities by reducing waste through the acquisition of eco-friendly equipment.
All fields of work

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Airport Improvement Program - Matching Grant (OH)

Ohio Department of Transportation
State/Local Government
Ohio
Unspecified amount
The Airport Improvement Program - Matching Grant in Ohio aims to enhance the safety and functionality of the state's airports. With approximately $7 million available this year, the program supports various projects at general aviation airports funded by the FAA AIP Grant program. Eligible sponsors include publicly owned airports that do not receive FAA Air Carrier Enplanement Funds. This initiative plays a crucial role in maintaining Ohio's robust airport infrastructure.
Aviation

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) (356925)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.
Integrative & Alternative Health Microbiomes

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed) (356717)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The National Cancer Institute (NCI) seeks to enhance the validation of biomarkers and assays for cancer detection and treatment through its UH3 funding mechanism. This initiative supports multi-disciplinary collaborations to validate existing assays over three years using clinical trial specimens. Emphasis is placed on harmonizing laboratory tests and validating pharmacodynamic markers. Projects should not focus on early-stage technology development but aim for integration into clinical studies as investigational assays.
Cancer / Oncology Biomedical Imaging

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed) (356718)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The National Cancer Institute (NCI) invites applications for the validation of molecular, cellular, and imaging markers for cancer detection and treatment. This funding opportunity supports both analytical and clinical validation phases, emphasizing multi-disciplinary collaboration. The UH2 phase focuses on analytical validation, while the UH3 phase extends to clinical validation using well-annotated biospecimens. Proposals should justify the relevance of assays for clinical use and may include harmonization efforts across laboratories.
Cancer / Oncology Biomedical Imaging

Emerging Global Leader Award (K43 Independent Clinical Trial Required) (356724)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Afghanistan, Albania +125 more
Approximately US $140,000
The Emerging Global Leader Award (K43) offers essential research support and protected time for early career scientists in low- and middle-income countries. This program, aligned with NIH's clinical trials policy, aims to cultivate independent research careers by providing mentorship and funding over three to five years. Eligible candidates must hold a junior faculty position at an accredited LMIC institution, fostering the growth of research capacity in their regions.
Aging / Gerontology Cardiovascular Diseases & Systems Hematological Systems +15 more

Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) (356723)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Afghanistan, Albania +125 more
Approximately US $140,000
The Fogarty Emerging Global Leader Award supports early career research scientists from low- or middle-income countries (LMIC) by providing research funding and mentored career development for three to five years. This program encourages LMIC scientists in health-related fields to develop projects aligned with their country's health priorities, fostering independent research careers within their institutions. Applications are welcomed from junior faculty members, enhancing global health research and capacity in LMICs.
Cancer / Oncology Neurological Diseases & Disorders Mental Health & Psychiatric Diseases +14 more

Ohio College Opportunity Grant (OCOG)

Ohio Department of Higher Education
State/Local Government
Ohio
Unspecified amount
The Ohio College Opportunity Grant (OCOG) is designed to assist Ohio residents with significant financial need, as determined by the FAFSA. Eligible individuals include those pursuing associate degrees or first bachelor's degrees at recognized institutions, with a maximum household income of $96,000. The grant adapts based on tuition costs, ensuring support for students in various programs, including foster youth and veterans at community colleges. This initiative fosters access to higher education across Ohio.
Education - Higher Education Academic Scholarship Programs

Governor’s Merit Scholarship (GMS)

Ohio Department of Higher Education
State/Local Government
Ohio
Up to US $5,000
The Governor’s Merit Scholarship (GMS) aims to retain Ohio's top high school graduates by providing financial support for higher education. Funded at $20 million annually, it awards up to $5,000 per year for four years to eligible students attending qualifying institutions in Ohio. The program encourages academic excellence and aims to reduce financial barriers, ensuring that outstanding students can pursue their education in-state, thereby contributing to the state's workforce and economy.
Education - Higher Education Academic Scholarship Programs

Body Worn Camera Grant Funding Request for Proposal

Ohio Office of Criminal & Justice Services
State/Local Government
Ohio
US $3,127 - US $122,720
The Ohio Body-Worn Camera Grant Program aims to enhance law enforcement transparency and accountability by providing funding for agencies to establish or upgrade their body-worn camera programs. With a budget of $10 million, the program prioritizes agencies without existing camera systems. In 2023, the average award was approximately $43,482, addressing crucial needs for improved evidence collection and officer training, ultimately fostering better community relations and public trust.
Police & Law Enforcement

NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional) (356763)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDCD Early Career Research (ECR) Award (R21) supports new scientists establishing independent research careers in areas related to hearing, balance, smell, taste, voice, speech, or language. This grant encourages innovative projects such as secondary data analysis, small research initiatives, and technology development, aiming to generate preliminary data for future R01 applications. All applications must be submitted by 5:00 PM local time of the applicant organization.
Hearing Disorders & Audiology Communication Disorders

Rise for Education Grant Program

Rise Gardens
Corporate
United States
Unspecified amount in in-kind support
The Rise for Education Grant Program offers funding for hydroponic classroom gardens that enhance STEM education and nutrition. This initiative encourages hands-on learning, integrating STEM and arts through practical gardening projects. Eligible applicants include schools, homeschooling families, and educational organizations. The program fosters community building and entrepreneurship via activities like Farmer's Markets, while boosting student engagement and developing essential skills. By implementing this program, educators can create an engaging and interactive learning environment year-round.
Horticulture & Gardening

All Kids Play: Youth Sports Grant - Organization

All Kids Play
Private
United States
Unspecified amount
The All Kids Play: Youth Sports Grant aims to support families and community-based organizations in low-income areas, ensuring access to recreational sports for children in grades K-12. This grant assists those who struggle to afford youth sports, providing essential funding on a first-come, first-served basis. Eligible organizations must demonstrate budget constraints and operate in areas with high low-income student percentages, promoting inclusivity in youth sports participation.
Youth Services Sports & Athletics Education - K through 12

WAEF Scholarships - Danna Gebbers Guzman Memorial

Washington Apple Education Foundation
Private
United States
Unspecified amount
The WAEF Scholarships, supported by the Washington Apple Education Foundation, offer over $1 million in educational awards to more than 300 students this year. These scholarships are primarily for individuals with ties to the tree fruit industry in Washington, with a special focus on the Danna Gebbers Guzman Memorial Scholarship, aimed at nursing students. Eligible recipients can use the funds at accredited institutions with nursing programs.
Agricultural Crops Nursing

GSF: Gilead Research Scholars - Liver Disease- Primary Biliary Cholangitis US

Gilead Sciences Foundation
Private
United States
Up to US $180,000
The Gilead Research Scholars Program focuses on innovative research in areas of unmet medical need, including Primary Biliary Cholangitis (PBC). Designed for early-stage investigators, it offers up to $180,000 in funding over two years to support projects addressing health inequities. The program prioritizes applicants from underrepresented groups and fosters diversity to enhance scientific progress. Successful candidates must demonstrate a commitment to research and have a mentor experienced in PBC.
Liver Disease

AbbVie Foundation Health Equity Accelerator

Abbvie Foundation
Corporate
United States
Up to US $60,000
The AbbVie Foundation Health Equity Accelerator seeks innovative solutions to enhance healthcare access for underserved communities. This program empowers nonprofit organizations by providing mentorship, resources, and financial support, including a $10,000 stipend for participants and a $50,000 grant for the best solution. By fostering community-led initiatives, the accelerator aims to address health disparities and improve the quality of care through tailored, grassroots approaches. Applications are encouraged from organizations rethinking care delivery models.
Patient Care & Services Health Disparities & Social Determinants of Health Health Care Access & Delivery +1 more

Sons and Daughters Scholarship Program

Cleveland Cliffs Foundation
Private
Canada, United States
US $3,000
The Sons and Daughters Scholarship Program, administered by the Cleveland-Cliffs Foundation, offers a competitive scholarship of $3,000 annually for up to four years for undergraduate studies. This initiative recognizes exceptional academic and extracurricular achievements among high school students. Scholarships are available to those attending accredited colleges or universities in the U.S. or Canada, though children of Cleveland-Cliffs officers are ineligible. The program aims to enhance educational opportunities and support community growth.
Academic Scholarship Programs

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health Pharmacology Drug Safety +1 more

Hamilton County Grants for Nonprofits Highlights

Looking for Hamilton County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Hamilton County grants recommended for your specific programs in Ohio.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Hamilton County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

85 Hamilton County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

13 Hamilton County grants for nonprofits over $25K in average grant size

8 Hamilton County grants for nonprofits over $50K in average grant size

12 Hamilton County grants for nonprofits supporting general operating expenses

73 Hamilton County grants for nonprofits supporting programs / projects

8,000+ Grants on Instrumentl focused on Education - Higher Education

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Hamilton County grants for Nonprofits?

Most grants are due in the fourth quarter.

Q1
21.6%
Q2
17.3%
Q3
30.4%
Q4
30.7%

Typical Funding Amounts

What's the typical grant amount funded for Hamilton County Grants for Nonprofits?

Grants are most commonly $7,500.

$250 $250 Min.
$7,500 $7.5 K Median
$25,644 $25.6 K Average
$182,500 $182.5 K Max.

Average Grant Size

What's the typical amount funded for Ohio?

Grants are most commonly $97,851.

$97,851

Total Number of Grants

What's the total number of grants in Hamilton County Grants for Nonprofits year over year?

In 2024, funders in Ohio awarded a total of 84,081 grants.

2022 78,879

2023 79,604

2024 84,081

Top Grant Focus Areas

Among all the Hamilton County Grants for Nonprofits given out in Ohio, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Hamilton County Grants for Nonprofits changing over time?

Funding has increased by -1.54%.

2022 $7,853,771,046

2023 $8,315,467,696
5.88%

2024 $8,187,079,289
-1.54%

Ohio Counties That Receive the Most Funding

How does grant funding vary by county?

Hamilton County, Cuyahoga County, and Franklin County receive the most funding.

County Total Grant Funding in 2024
Hamilton County $3,320,115,009
Cuyahoga County $2,821,239,308
Franklin County $2,035,647,424
Summit County $545,376,601
Scioto County $393,048,909

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