Best Grants for Nonprofit Healthcare Programs in California

Nonprofit organizations in California offering health care access, wellness, mental health, or related services can apply for John Jordan Foundation’s John Jordan Foundation Grant to support programs improving quality of life for vulnerable communities. Funding may also benefit initiatives serving youth, seniors, families, and under-resourced populations alongside healthcare-focused work.

First- and second-year medical students conducting health-related research in California can access funding through Alpha Omega Alpha’s Carolyn L. Kuckein Student Research Fellowship, which awards US $7,000 for 2–12 month projects. Eligible projects include clinical investigation, basic laboratory research, epidemiology, health services, social science, leadership, or professionalism studies at schools with active AΩA chapters.

California nonprofit 501(c)(3) organizations providing practical support that helps pregnant people access abortion care can receive funding for transportation, lodging, childcare, meals, wage replacement, and related services. California healthcare access groups can access funding through the California Department of Health Care Access and Information, administered by Essential Access Health, with awards ranging from US $100,000 - US $750,000.

Nonprofit 501(c)(3) organizations running healthcare and health equity projects in California can seek funding for defined community health improvement initiatives. With a mission to improve health and advance social justice, Commonspirit Health provides grants up to US $150,000 through participating hospitals to address needs identified in community health needs assessments.

California 501(c)(3) nonprofits offering healthcare, education, or arts programs for children and women can apply for project or capital funding that excludes most operating costs. Grants from Douglas Foundation help organizations in California, with preference for Los Angeles County, expand equitable access to health care and related community services.

California community development financial institutions (CDFIs) supporting affordable housing, health care, small business lending, and other services in low- and moderate-income communities can use these grants for working capital and to increase net assets. With a mission to strengthen community development, California State Treasurer's Office provides California CDFIs with up to US $200,000 based on recent lending activity.

Nonprofit and other organizations improving health care access and delivery in California can apply for project-based funding that advances coverage, people-centered care, workforce, technology, or policy. With a mission to strengthen California’s health system, California Health Care Foundation provides support for initiatives benefiting low-income residents and Medi-Cal populations, including research, innovation, and statewide or multi-institution efforts.

Nonprofit public charities in California seeking support for healthcare, health care access and delivery, social services, and related programs can apply for the Harold McAlister Charitable Foundation’s grants. With a mission to support effective organizations in bettering the lives of others, the foundation also considers education, animal welfare, arts and culture, and environmental initiatives.

Nonprofit and other organizations supporting community health workers in California can apply for California Health Care Foundation’s Amplifying Impact Initiative, which funds scaling of CHW/P/R Medi-Cal providers. Over 18 months, 28 providers receive grants, technical assistance, and tools to expand culturally responsive health and social services and strengthen CHW/P/R jobs.

Grants from Astrazeneca Foundation help California nonprofit healthcare and community organizations address health equity through nutrition and food security, healthcare access, STEM education, and climate and nature initiatives. U.S.-based 501(c) groups serving historically excluded or disenfranchised communities in California can apply for up to US $30,000 for community-based programs, excluding capital projects, salaries, and hospitals.

Nonprofit organizations in California focused on health care and human services may be eligible for funding that supports community-focused healthcare access and related programs. Focused on arts, education, youth, community, and global food and agriculture, J R Simplot Company Foundation invites U.S. nonprofits to apply; requests are reviewed quarterly.

Early- through growth-stage U.S.-incorporated companies improving health care access and delivery for low-income Californians can apply for up to US $400,000 to scale technology and innovation solutions. Grants from California Health Care Foundation help California-focused healthcare innovators build partnerships with providers, health systems, payers, and patients, which may benefit nonprofit healthcare programs statewide.

Nonprofit organizations in California working on health care access, mental health, or education for underserved populations can apply for US $10,000 - US $75,000 in program funding from L B Research and Education Foundation. The foundation supports established 501(c)(3)s expanding proven, research-informed programs for adolescents, post-secondary students, and adult vocational learners through a rolling, concept-paper-first process.

Nonprofit 501(c)(3) organizations in California working on health care access and delivery, early childhood education, conservation, or family services can seek capital or special project funding that supports community programs. Grants from James M Cox Foundation help U.S. nonprofits in Cox service areas, with preference for groups engaged with local Cox businesses.

Nonprofit 501(c)(3) small or rural health facilities in California can apply for low-interest loans from the California State Treasurer's Office; awards US $25,000 - US $1,500,000 for facility expansion and equipment. Funds may support construction, renovation, furnishings, feasibility studies, pre-construction costs, or refinancing a single existing debt, with a 5% borrower contribution required.

Nonprofit organizations improving community access to quality healthcare in California can apply for the Astrazeneca Foundation’s CHANGE grants, awarding US $200,000 - US $220,000 in general operating support. Programs using innovative, collaborative approaches to address health care access, delivery, and related equity issues may be considered, with potential for multi-year renewal based on performance.

Nonprofit 501(c)(3) agencies with budgets under $10M in California can seek funding to initiate or expand health, mental health, and related social service programs. Charis Fund supports healthcare access, housing, food insecurity, at-risk youth, domestic violence, and substance abuse initiatives with grants of US $2,500 - US $7,500, prioritizing program and project support.

Nonprofit 501(c)(3) healthcare and community organizations in California working on mental health or substance use disorder treatment, prevention, or loneliness reduction can apply for Elevance Health Foundation’s Behavioral Health Grant. This U.S.-wide opportunity prioritizes scalable national or local programs, strong outcome tracking, and culturally relevant, whole-person care approaches within healthcare and related settings.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

The Amyloidosis Fund, managed by the HealthWell Foundation, provides essential financial assistance to underinsured patients facing treatment costs for Amyloidosis. The program covers prescription copays, insurance premiums, and related expenses, ensuring that patients can access necessary medications without financial strain. With a maximum award of $8,000, the fund aims to alleviate the burden of healthcare costs for those diagnosed with this complex disease, promoting better health outcomes and quality of life for patients across the United States.

The Alagille Syndrome Vitamins and Supplements Fund, managed by the HealthWell Foundation, offers financial assistance to patients suffering from Alagille Syndrome. This fund helps cover the costs of essential vitamins and supplements needed for treatment. With a maximum award of $1,500, the program aims to reduce financial barriers for underinsured individuals, ensuring they receive the necessary support to manage their health, thereby enhancing their quality of life.

The Kei Lin Foundation Grant, established in 2012 by Margaret Tsai, honors her mother, Kei Lin. This grant supports charitable organizations that provide essential services such as housing, food, and medical assistance to senior citizens and veterans. Priority is given to tax-exempt organizations under 501(c)(3) status. Applicants must adhere to specific guidelines and provide regular reports on fund usage to ensure transparency and accountability in their operations.

The Broadcasters Foundation of America Monthly Grant provides essential financial assistance to broadcasters facing acute hardships due to serious illnesses or accidents. This initiative aims to support those who have dedicated significant years to the broadcasting profession, ensuring they receive medical aid and relief from financial burdens. Eligible applicants can apply for monthly grants if they meet specific employment and hardship criteria, helping them navigate difficult times with dignity and support.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The NIHCM Foundation Investigative and General Reporting Award honors outstanding reporting that enhances understanding of U.S. health care affordability and quality. A $20,000 prize is awarded to the winner, with entries evaluated for quality, originality, and impact. Eligible submissions include stories published in 2025 from national outlets, focusing on insightful reporting that informs health care policymakers and consumers about rising costs and access solutions.

The National Institute of Dental and Craniofacial Research (NIDCR) is set to announce a funding opportunity for clinical trials and observational studies within its Dental Primary Care Practice-Based Research Network (PBRN). This initiative aims to enhance the integration of oral and medical health by facilitating research conducted in dental practices. While applications are not currently being accepted, this notice serves to encourage collaborations that will lead to impactful projects in whole-person health.

The nccPA Health Foundation: Kathy J. Pedersen Grant aims to promote equitable health care by providing up to $5,000 for innovative projects that address health disparities. This grant honors Kathy J. Pedersen's legacy and encourages applicants to develop actionable strategies that foster cultural humility, advocate for underserved populations, and improve public health. Grantees are expected to demonstrate a commitment to sustainability and social accountability in their proposed initiatives.