Best Madison County Grants for Nonprofits in North Carolina

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

The Placement and Coordination Program, administered by the Office of Refugee Resettlement, invites eligible organizations to enhance refugee resettlement services. By diversifying service providers, the program aims to strengthen the national resettlement framework. Key responsibilities include managing the Program of Initial Resettlement and Intensive Case Management for vulnerable refugees, ensuring comprehensive support from arrival through initial resettlement, and addressing barriers to self-sufficiency.

NC DEQ 319 Grant Program

Through Section 319(h) of the Clean Water Act, the U.S. Environmental Protection Agency provides states with funding to reduce nonpoint source pollution. North Carolina typically receives around $1 million for competitive funding of watershed restoration projects. Funds may be used to conduct watershed restoration projects such as stormwater and agricultural best management practices and restoration of impaired streams. Section 319 grant projects must be used to help restore waterbodies currently impaired by nonpoint source pollution in areas with approved watershed restoration plans. (map) (list)

State and local governments, interstate and intrastate agencies, public and private nonprofit organizations, and educational institutions are all eligible to apply for 319 funding. An interagency workgroup reviews the proposals and selects those of merit to be funded. 

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

• Training programs
• Programs that engage new adopters and grow the market share for adoption
• Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
• Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

• Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
• Decrease length of stay
• Decrease cost of care
• Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.

NC Supportive Housing Development Program (SHDP)

The North Carolina Housing Finance Agency offers several programs to help nonprofit organizations and local government entities build and rehabilitate emergency, transitional, and permanent housing for people who are experiencing homelessness or at imminent risk of homelessness, have disabilities or other special needs.

The Supportive Housing Development Program (SHDP) aims to increase the supply of emergency, transitional and permanent supportive housing for special populations and low-income households.

Supportive Housing Development Program-Veterans (SHDP-Veterans)

New for the 2026 cycle, SHDP-Veterans financing is available for acquisition, rehabilitation, and/or new construction of emergency, transitional, or permanent housing serving veterans who are homeless or imminently at risk of homelessness.

The housing must serve households who earn below 50% of area median income. Rent and utilities cannot exceed 30% of the gross household income. 

NC Supportive Housing Development Program (SHDP)

The North Carolina Housing Finance Agency offers several programs to help nonprofit organizations and local government entities build and rehabilitate emergency, transitional, and permanent housing for people who are experiencing homelessness or at imminent risk of homelessness, have disabilities or other special needs.

The Supportive Housing Development Program (SHDP) aims to increase the supply of emergency, transitional and permanent supportive housing for special populations and low-income households.

Supportive Housing Development Program-Integrated (SHDP-Integrated)

New for the 2026 cycle, SHDP-Integrated financing is available for acquisition, rehabilitation, and/or new construction of permanent rental housing serving people with disabilities in an integrated setting.

The housing must serve households who earn below 50% of area median income. Rent and utilities cannot exceed 30% of the gross household income. 

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

• The tools, templates and training they need to start right away;
• A shared brand they can plug into on day one;
• A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

The FY26 Neurofibromatosis Research Program's Synergistic Idea Award supports innovative research on neurofibromatosis (NF) through collaborative efforts of two or three Principal Investigators (PIs). By leveraging their unique perspectives, these PIs will tackle significant questions in NF research. Applicants must provide relevant preliminary or published data to support their proposals, ensuring a strong foundation for impactful research outcomes.

The DoW Neurofibromatosis Investigator-Initiated Research Award addresses critical needs in neurofibromatosis research, aiming to enhance patient care through innovative projects. It supports various research phases, excluding clinical trials, and encourages collaboration between scientists and clinicians. The funding mechanism includes two levels based on participation in optional features, such as the Open Science Initiative and collaboration with qualified partners, promoting data sharing and collaborative research efforts.

The Value Assessment and Health Outcomes Research Postdoctoral Fellowship, funded by the PhRMA Foundation, offers a $60,000 stipend annually for up to two years. This fellowship supports researchers, both U.S. and non-U.S. citizens, engaged in innovative studies aimed at evaluating the effectiveness and value of healthcare interventions. Applicants must be within five years of postdoctoral study and hold a relevant doctoral degree. This opportunity fosters collaboration and patient engagement in health outcomes research.

The Value Assessment and Health Outcomes Research Predoctoral Fellowship, offered by the PhRMA Foundation, supports promising students in their advanced training and thesis research. This fellowship, aimed at U.S. and non-U.S. citizens, provides $30,000 in annual stipend support for up to two years. It encourages research proposals that address the effectiveness, safety, and value of healthcare interventions, emphasizing patient engagement and health equity in the evaluation process.

The Value Assessment and Health Outcomes Research Faculty Starter Grant, offered by the PhRMA Foundation, supports emerging researchers at U.S. universities. With a funding of $100,000 for one year, it aims to advance studies on the effectiveness and value of healthcare interventions. The grant promotes innovative research in areas such as clinical outcomes, health equity, and patient engagement, ensuring that diverse perspectives are included in the evaluation of healthcare solutions.

The Translational Medicine Postdoctoral Fellowship by the PhRMA Foundation supports U.S. and non-U.S. citizens in multidisciplinary research training at accredited U.S. universities. The program aims to enhance credentials in translational medicine, focusing on turning laboratory observations into effective medical interventions. The fellowship includes a stipend of $60,000 per year for 12 to 24 months, promoting innovative research that addresses unmet clinical needs in various scientific disciplines.

The College Well-Being Funding Opportunity aims to enhance the health of college students through innovative programs and research. Offered by the American College Health Foundation, it provides up to two awards of $3,500 to eligible institutions for improving campus infrastructure that promotes student well-being. This initiative encourages creativity and collaboration among campus health professionals to develop effective, measurable outcomes in student wellness. By fostering a culture of well-being, the foundation seeks to address the evolving needs of contemporary students.

The Beth N. Rom-Rymer Travel Scholarship provides $1,000 for Native psychology graduate students to attend the American Psychological Association's annual convention. This opportunity is specifically for members of the Society of Indian Psychologists (SIP). The scholarship aims to support diverse applicants and encourages first-time attendees who demonstrate financial need. APF, the funding organization, is dedicated to enhancing the field of psychology by supporting early career professionals and their contributions to societal improvement.

The Drug Discovery Predoctoral Fellowship by the PhRMA Foundation supports PhD candidates engaged in thesis research in drug discovery. This fellowship offers $30,000 annually for 12 to 24 months, encouraging innovative research that integrates multiple scientific disciplines. Applicants must be full-time, in-residence students at accredited U.S. universities and have completed significant coursework. The funding is conditional upon continued enrollment and is intended for stipend support, with some funds allowable for research-related incidentals.

The Drug Delivery Predoctoral Fellowship by the PhRMA Foundation supports promising PhD candidates in drug delivery research at accredited U.S. universities. It provides $30,000 per year for 12 to 24 months, aimed at enhancing the understanding of drug formulation and delivery technologies. The fellowship emphasizes innovative research that leads to improved patient outcomes and fosters collaboration among diverse research teams, ensuring that all individuals have access to groundbreaking medicines.

The PhRMA Foundation offers a Drug Delivery Postdoctoral Fellowship aimed at fostering biopharmaceutical innovation and enhancing research capabilities in drug delivery. This fellowship supports both U.S. and non-U.S. citizens who are involved in collaborative research training at accredited U.S. universities. Awardees receive a stipend of $60,000 per year for 12 to 24 months, with funding contingent on ongoing employment in the postdoctoral program. Ideal candidates are encouraged to expand their skills in new research environments.

The Drug Discovery Postdoctoral Fellowship by the PhRMA Foundation supports researchers in a multidisciplinary training program at accredited U.S. universities. Aimed at enhancing credentials in drug discovery, it funds innovative research with potential human applications. Proposals should focus on biological validation of drug targets across various scientific disciplines. The fellowship provides $60,000 in annual stipend support for up to 24 months, contingent on the awardee's continued employment at the university.

The Drug Discovery Faculty Starter Grant, offered by the PhRMA Foundation, supports early-career researchers in drug discovery at U.S. universities. With a funding amount of $100,000 for one year, this grant is targeted at faculty members within five years of their independent status. The program aims to foster innovative research that integrates various scientific disciplines, ultimately leading to novel treatments for patients. Eligibility extends to full-time faculty members eligible for promotion.

The Drug Delivery Faculty Starter Grant from the PhRMA Foundation supports early-career researchers in drug delivery, providing $100,000 for one year. Eligible applicants include full-time faculty at accredited U.S. universities within their first five years of independent status. The grant emphasizes innovative research that enhances drug transport and dosage forms. Recipients must notify the Foundation of any external funding exceeding $250,000. This initiative aims to foster scientific independence and collaboration in biopharmaceutical innovation.

The SUS Mid Career Award offers $40,000 for one year to SUS members in the US or Canada with prior research funding, supporting their ongoing work in surgical sciences. Eligible applicants must have experience as a principal investigator on independent or smaller grants, or hold a career development award. This award serves as bridge funding for those who have recently applied for independent grants but were not funded, fostering continued research and innovation.

The SUS Resident Research Scholar Award offers $30,000 for one year to surgical residents engaged in basic or translational research. Eligible candidates must have completed two years of training and commit to full-time research with an SUS member. Notably, applicants must avoid mentors on the exclusion list, ensuring a fair and competitive application process. This funding promotes innovative surgical research and supports the development of future leaders in the field.

The American Surgical Association's Surgical Leaders Fellowship Grant aims to develop future academic surgical leaders while promoting diversity in leadership roles. The program includes shadowing experiences and skill development, allowing fellows to assess their readiness for leadership positions in surgery. Each fellowship provides $5,000 in funding for visits to two academic institutions, enhancing professional growth through mentorship with established leaders in the field.

The FFAR Fellows Program offers professional development and leadership training for PhD students in food and agriculture sciences across the U.S. and Canada. Led by North Carolina State University, the program includes in-person meetings, virtual sessions, and mentorship opportunities. Students receive a combined stipend of $65,000 annually, with a minimum of 50% sponsorship from non-academic sources. The program emphasizes interdisciplinary collaboration, career exploration beyond academia, and the development of essential skills for future leaders in the field.

The FFAR Fellows Program, led by North Carolina State University, provides PhD students in food and agriculture sciences with essential leadership and professional development training. Over three years, fellows engage in in-person meetings, virtual sessions, and mentorship opportunities, enhancing their skills and networking. Applicants must be enrolled in a PhD program, have a confirmed financial sponsor, and demonstrate readiness to participate. This initiative promotes interdisciplinary collaboration and broadens career pathways beyond academia.