Best Large Grants for Nonprofit Organizations in Minnesota

The Dr. Eric W. Bond “Kickstart” Scholarship, initiated by the Community Foundation of the Central Blue Ridge, honors Dr. Bond's dedication to education. It supports three graduating seniors from each Augusta County public high school, focusing on those entering the workforce directly. The scholarship emphasizes financial need, community service, and extracurricular involvement, reflecting Dr. Bond's values. The inaugural scholarships will be awarded in 2026, ensuring a lasting legacy that enriches students' lives and promotes their successful transition into adulthood.

The H. Branch Howe Grant, offered by the Georgia Ornithological Society, supports graduate students conducting ornithological research in Georgia. This grant encourages the scientific study of birds and conservation efforts, providing funding for research that enhances knowledge of avian life. Eligibility is limited to graduate students in Georgia, and preference is given to projects within state boundaries. The GOS aims to foster collaboration and knowledge sharing among those passionate about birds and nature.

About National Fish and Wildlife Foundation (NFWF)

The National Fish and Wildlife Foundation (NFWF) works with partners to foster sustainable and impactful conservation solutions so that people and nature thrive together. Chartered by Congress in 1984, NFWF has grown to become the nation’s largest conservation foundation. Since its founding, NFWF has funded more than 23,900 projects that have generated a total conservation impact of more than $12 billion.About Sustain Our Great Lakes Program

Sustain Our Great Lakes is a public–private partnership designed to sustain, restore and protect fish, wildlife and habitat in the basin by leveraging funding, building conservation capacity, and focusing partners and resources toward key ecological issues. The program achieves this mission, in part, by awarding grants for on-the-ground habitat restoration and enhancement.Funding priorities for this program include:

• Habitat Restoration to Conserve Species and Improve Water Quality
• Expand and Maintain Nature-Based Solutions in Great Lakes Communities
• Invasive Species Control to Protect and Enhance Restored Habitat
• Activate Restored Habitats and Natural Areas

The NIAAA Integrative Neuroscience Initiative on Alcoholism (INIA) aims to renew support for two research consortia focusing on the biological mechanisms of excessive alcohol consumption and Alcohol Use Disorder (AUD). By utilizing advanced technologies and fostering collaboration across multiple sites, this initiative seeks to standardize neurofunctional measures and enhance reproducibility in findings. Investigators are encouraged to prepare for future applications to this NOFO, which will utilize the U24 activity code.

The Higher Education Challenge Grants Program, managed by the USDA's National Institute of Food and Agriculture, aims to enhance institutional capacities in food and agricultural sciences education. This initiative focuses on improving curriculum, faculty, and student recruitment for master's and doctoral programs, particularly in veterinary medicine. By strengthening these educational frameworks, the program seeks to ensure the availability of skilled professionals in critical agricultural sectors.

The Aerie Real Foundation™ Community Grant aims to enhance confidence, inclusion, and sustainability among young women while supporting non-profit organizations in the US and Canada. Grants of up to $10,000 are available to programs focused on mental well-being, fostering inclusive communities, and environmental protection. Applications are accepted from certified 501c3 nonprofits, with funding allocated for projects that align with the Foundation's mission. The goal is to empower the next generation and create a positive impact in local communities.

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

Common Waters: Strengthening Community-based Coastal and Riverine Stewardship

Opportunity Overview

Projects supported by this RFP must be community-based stewardship initiatives (including but not limited to stewardship driven by Indigenous and descendant communities); they should be led by an individual with a strong connection to and/or an existing track record of work in the community(ies) where the project will take place, or by a member of the community themselves, and be designed in response to community needs. Projects can focus on a wide range of specific issues, including (but not limited to) local conservation and ecosystem restoration, climate change adaptation and resilience, or sustainable fishing/agriculture. The RFP will prioritize projects in National Geographic-Lindblad Expeditions destinations, including the Arctic, Asia, Baja California, Costa Rica and Panama, Europe and the Mediterranean, Patagonia, the Peruvian Amazon, the Pacific Northwest, Southeast Alaska and British Columbia, the South Pacific, and the United Kingdom and Ireland. For more detailed information on targeted areas within these regions, please refer to the targeted areas document.

The Lundbeck US Charitable Fund focuses on enhancing brain health through sponsorships that support various initiatives. These sponsorships are available to both non-profit and for-profit organizations, provided they align with Lundbeck's mission. Funds are primarily allocated for educational or awareness events, with an emphasis on community outreach and collaboration to address gaps in care, especially for vulnerable populations. By fostering innovative strategies, the Fund aims to drive meaningful change in the field of brain health.

This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.

The Lundbeck US Charitable Fund focuses on enhancing brain health through impactful donations. Established to support organizations dedicated to brain health, it addresses pressing needs by funding innovative strategies and community collaborations, particularly for at-risk populations. The Fund aims to transform lives and improve mental health care, with a commitment to responsible giving. With over 20 organizations supported in 2023, it drives meaningful change in communities affected by brain disorders.

The AISES Stellantis Scholarship aims to enhance the representation of Indigenous peoples in STEM fields. Funded by Stellantis, this scholarship offers $20,000 for full-time students enrolled in colleges with Mopar Career Automotive Programs. Eligible candidates must be current AISES members and either enrolled citizens or descendants of recognized Indigenous groups. The program not only supports education but also fosters a diverse and inclusive workforce within the automotive industry.

The General Surgery Resident Research Initiation Grant aims to engage General Surgery Residents in research related to colorectal diseases. With an annual funding of $20,000, this grant supports both clinical and laboratory-based research. It is geared towards residents or recent graduates of approved General Surgery programs, prioritizing those with aspirations in Colon and Rectal Surgery. This initiative fosters innovative research to enhance patient care and surgical techniques in the field.

The Yamaha Outdoor Access Initiative supports outdoor enthusiasts and promotes responsible use of off-highway vehicles (OHVs). Its mission includes educating the public on land use and wildlife conservation while protecting access to public lands. Applications are accepted quarterly from nonprofit organizations and community groups focused on land stewardship and access improvements, ensuring a safe and sustainable outdoor experience for all.

The AISES Indian Motorcycle Academic Scholarship offers $5,000 annually to support Native students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship aims to empower Indigenous students and enhance diversity in STEM. Eligible applicants must be current AISES members, full-time students, and enrolled citizens or descendants of recognized Native tribes. This scholarship not only provides financial assistance but also fosters community and innovation within the STEM landscape.

The Hawk Watch Fund Grant, established by the Hawk Migration Association of North America (HMANA), supports hawk watch sites in North America facing funding challenges. Grants of up to $1000 are available for volunteer-based projects that align with HMANA's mission of promoting raptor conservation and migration study. Funding is sourced from HMANA's annual Raptorthon and donations. This initiative aims to enhance educational resources, equipment acquisition, and operational support for hawk watch groups.

The Kalamazoo Valley Chapter's Stanley Weber Projects Fund honors a dedicated member by supporting projects that enhance coldwater fisheries and their habitats. Offering grants up to $5,000 annually, the fund prioritizes non-profit initiatives that foster conservation, restoration, and public education while promoting volunteer engagement. Recognition through plaques or media announcements is requested for grant recipients, ensuring the legacy of Stanley Weber continues to impact the community positively.

The Wirtanen Family Fund supports initiatives aimed at fostering community awareness of global interdependence, promoting social justice, and increasing democratic participation. It prioritizes projects addressing contemporary issues with regional impact, such as health care access and environmental preservation. Eligible organizations include those classified as charitable under IRS codes and serving specific counties in Minnesota and Wisconsin. The fund encourages co-sponsorship and highlights the importance of understanding diverse cultures and social systems.

The Eugene Salvati, MD, Limited Project Grant, offered by the Research Foundation of the American Society of Colon and Rectal Surgeons, supports clinical research in colorectal surgery. This grant aims to honor Dr. Salvati's legacy by funding innovative projects that improve patient care. With a maximum funding of $25,000 for one year, it emphasizes investigator-initiated research conducted within the U.S. or Canada, encouraging collaboration among ASCRS members and adherence to ethical review board protocols.

The PositiveNRG Grant Program, led by NRG Energy, focuses on investing in communities through choice and education, community engagement, resilience, sustainability, and well-being. The program is open to non-profit organizations and governmental entities that can demonstrate a meaningful impact. Preference is given to initiatives that foster community involvement and inclusiveness. However, sponsorships for religious or political activities are generally not supported. This program aims to empower communities through innovative energy solutions.

The Research Foundation of the ASCRS offers the Limited Project Grant to support innovative research in colon and rectal surgery. With funding up to $25,000 for one year, this grant aims to foster investigator-initiated, hypothesis-driven projects conducted in the U.S. or Canada. Successful applicants may secure further funding from national agencies. ASCRS membership is required for principal investigators, ensuring a dedicated approach to advancing colorectal health and surgical techniques.

The AWWA Jacobs Holly A. Cornell Scholarship, established in 1990, supports graduate students pursuing water supply and treatment studies. Sponsored by Jacobs/CH2M, this $10,000 scholarship is aimed at first-generation college graduates or those who have faced economic disadvantages and significant educational barriers. AWWA, the largest organization of water supply professionals, emphasizes the importance of investing in the future of the water industry through such scholarships.

The BSF Research Grants program supports collaborative research between U.S. and Israeli scientists, focusing on basic science projects. Annually, approximately 400 applications are submitted, with around 100 grants awarded. To foster collaboration, joint publications are essential for evaluation. Applications are accepted once per year in mid-November, with results announced the following July. Since its inception in 1972, the BSF has funded over 5,400 high-quality research initiatives, distributing more than $700 million.

The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.

The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.

The Friends of Reservoirs: Mossback Grant offers three grants of $1,000 in Mossback products to eligible members of Friends of Reservoirs organizations. Sponsored by Mossback Fish Habitat, these grants aim to enhance structural habitat in public waters. The total retail value is approximately $1,500. Applicants must cover freight costs, and a $25 application fee applies to each submission. This initiative supports habitat restoration efforts across member organizations.

The Limited Competition Small Grant Program for NIDDK K01/K08/K23/K25 recipients offers funding opportunities for pilot studies and feasibility research. This program aims to support researchers transitioning to independent investigator roles by providing resources for small projects that can yield preliminary data for future R01 applications. Key deadlines for applications range from February 2025 through January 2028, with specific dates for standard, renewal, and AIDS-related applications.