Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Grants for 501(c)(3) in Missouri

Find the perfect Grants for 501(c)(3) in Missouri on Instrumentl. 10,000+ Grants for 501(c)(3) in Missouri in the United States.

10,000+

Available grants

$2.59B

Total funding

$5K

Median grant

10,000+ grants
$2.59B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,663 Results based on applied filters

Harris & Frances Block Foundation Grant

Harris and Frances Block Foundation
Private
United States
Up to US $35,000
The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.
Food Access & Hunger Environmental Justice & Advocacy Agricultural Education +2 more

Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.
Infectious & Parasitic Diseases Addiction & Substance Use Disorders Drug Use Disorder

Smart Growth America: Community Connectors Grant Program

Smart Growth America
Private
American Samoa, Guam +4 more
Up to US $25,000
The Smart Growth America Community Connectors Grant Program supports small and mid-sized cities in addressing divisive infrastructure caused by dangerous roads. With funding from the Robert Wood Johnson Foundation, this program aims to reconnect communities through temporary street safety projects while fostering skills and partnerships. Eligible teams must represent populations of 50,000 to 500,000 and include both government and community-based organizations. Priority will be given to projects benefiting low-income communities historically affected by disinvestment.
Pedestrian & Bike-Friendly Infrastructure Public Infrastructure Public Transportation & Mass Transit Systems +1 more

Collections-Related Grants

Carl And Marilynn Thoma Foundation
Private
United States
Unspecified amount
The Carl & Marilynn Thoma Foundation offers Collections-Related Grants for Nonprofits, aimed at enhancing public interest in art through innovative projects. Grants support exhibitions, academic convenings, research, and catalog publication, focusing on art from the Spanish Americas, digital media, and more. The foundation prioritizes proposals from 501(c)(3) organizations in the U.S., particularly from New Mexico, Oklahoma, and Texas, fostering partnerships that advance art scholarship and cultural engagement.
Asian Art Folk Art / Traditional Art Media Arts +5 more

Dean John A. Knauss Marine Policy Fellowship

Woods Hole Oceanographic Institution (WHOI)
Private
American Samoa, Guam +4 more
Unspecified amount
The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.
Marine Biology Marine / Ocean Conservation Environmental Policy +2 more

Center for Family Engagement Healthy Minds Fellowship

National Congress of Parents & Teachers
Corporate
United States
US $1,000
The Center for Family Engagement Healthy Minds Fellowship, organized by the National PTA, invites active PTA leaders to enhance their mental health expertise over a 12-month cohort starting January 2026. Participants will receive a $1,500 stipend and engage in developing actionable plans to improve mental health initiatives in schools. This fellowship aims to empower leaders through workshops and collaborative efforts, fostering a supportive environment for mental wellness in educational settings.
Child Welfare Services Children’s Mental Health Parenting Counseling & Education +2 more

Lucas Tree Experts Integrated Vegetation Management Endowed Research Fund

Tree Fund
Association/Society
Canada, United States
Up to US $25,000

Tree Research and Education Endowment Fund (TREE Fund)

TREE Fund is a 501(c)3 nonprofit whose mission is to support scientific discovery and dissemination of new knowledge and best practices in the fields of arboriculture and urban forestry.

TREE Fund’s research and education programs shape industry best practices, improve workforce safety and contribute to the long-term sustainability of our communities in the following crucial ways:

  • Improving the quality of nursery grown trees and overall tree survival through the development of hardier, drought- and disease-resistant species.
  • Stopping diseases and pests while reducing pesticide use with the evolution of integrated pest management programs.
  • Enhancing public and workforce safety with advanced tree risk assessment techniques and greater knowledge about why and how trees fail.
  • Quantifying the benefits of trees which makes it easier for governments and businesses to project their return on tree care investment.
  • Revolutionizing global best practices for growing strong, healthy landscape trees.
  • Connecting youth with nature to promote environmental stewardship in the next generation and inspire them to consider careers in green industries.

Lucas Tree Experts Integrated Vegetation Management Endowed Research Fund

Since 1926, John Lucas Tree Expert Co. has worked with investor-owned utilities, electric cooperatives, municipalities, railroads, and pipeline customers throughout the United States and Canada. Innovation has always been a core value, and Lucas remains committed to innovation that makes the industry safer, greener, and more efficient. The Lucas Tree Experts Integrated Vegetation Management Endowed Research Fund is a new endowment fund of Tree Research and Education Endowment (TREE) Fund created to support research in Integrated Vegetation Management in the United States and Canada.

This fund program was created in 2026 to help celebrate Lucas Tree’s 100th anniversary. Lucas Tree’s anniversary marks a century of innovation, safety, and stewardship in utility vegetation management.

Projects are expected to be completed within one to three years. No project may receive more than one award from this program.

Application Requirements can be found here.

Plant Science Forestry Botanical Conservation

Park Foundation: Media Grants

Park Foundation, Inc.
Private
United States
Unspecified amount
The Park Foundation Grants: Media support public interest media that raises awareness of critical environmental and social issues. They prioritize funding for investigative journalism, media policy, public broadcasting, and documentary films to promote a better-informed citizenry. Eligible organizations must be 501(c)(3) certified, and funding is aimed at projects that ensure diverse perspectives and community engagement. The foundation is committed to fostering a robust democracy and independent media, reflecting its mission to advance a just and sustainable society.
Journalism Radio Television +2 more

Tee It Up for the Troops Grant

Tee It Up For The Troops Inc
Private
United States
Unspecified amount
Tee It Up for the Troops Grant supports 501(c)3 organizations that aid military personnel and their families. Prioritizing employment, family support, housing, PTSD treatment, sports rehabilitation, and suicide prevention, the grant aims to enhance the lives of veterans. Organizations that do not engage in fundraising events are eligible for funding. This initiative seeks to create a positive impact within the military community through various support pillars.
Military & Veterans Services Suicide Prevention Brain Injuries +1 more

Michael & Susan Dell Partnerships

Michael & Susan Dell Foundation
Private
Africa, India +2 more
Unspecified amount
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Poverty Alleviation & Services Education - Preschool / Early Learning Education - K through 12 +4 more

Jennie Wade Scholarship Endowment

Community Foundation of Wabash County
Private
United States
Unspecified amount

About Us

Our Mission

We create lasting impact through asset development, nonprofit capacity building, and community leadership. 

Our Vision

To enrich the lives of Wabash County residents by fostering opportunity, inspiring generosity, and building a thriving connected community. 

Our Scholarships

For High School Seniors & Non Traditional Students who are beginning college more than one year after high school.

The Community Foundation of Wabash County offers a wide variety of post-secondary education scholarships to traditional, non-traditional, and graduate students. With nearly 70 different scholarship endowments created through the generosity of our donors, many students are eligible to apply.    

Jennie Wade Scholarship Endowment

More than one hundred years ago, Jennie Wade created a scholarship in her words “to benefit mankind.” This scholarship is made to help young men and women continue their education after high school. Wabash County residents under the age of 21 are selected from among applicants who have done as much as possible in helping themselves obtain an education and whose families are unable to provide an education.

Workforce Preparation & Job Readiness Career / College Preparation Education - Higher Education +3 more

NBO Foundation - Education Committee Grants

Nicholas B. Ottaway Foundation
Private
United States
Unspecified amount
The Nicholas B. Ottaway Foundation offers grants through its Education Committee to support programs enhancing educational opportunities for economically disadvantaged students. These grants focus on initiatives like tutoring, college preparation, and internship programs. To qualify, organizations must be tax-exempt under 501(c)(3). Preference is given to projects that provide ongoing support to students post-graduation, particularly in specific geographic areas such as San Diego County and the New York Metropolitan Area.
After School / Summer Educational Programs Tutoring & Mentoring Standardized Testing Services +2 more

American Association of University Women / Wagy Fund

Greater Kansas City Community Foundation
Private
Cass County, Missouri, Clay County, Missouri +4 more
US $1,000 - US $4,000
The American Association of University Women / Wagy Fund supports initiatives that empower women and girls in Kansas City, Missouri. By promoting education, economic opportunity, and personal safety, the fund seeks to foster societal change. It prioritizes partnerships with organizations that share its mission and focus on measurable improvements in self-image and lifelong education. Eligible applicants must be public charities dedicated to benefiting women and girls in the region.
Women & Girl Services Women's Health Women's Rights & Equality +4 more

Headstream Accelerator Cohort VI Grant

Headstream by Second Muse
Corporate
United States
US $30,000

Headstream Accelerator 2026

Accelerator Application Cohort VI

The Headstream Accelerator supports entrepreneurs from all backgrounds in scaling digital solutions that improve the mental well-being of teens at risk, with a focus on the education and healthcare sectors. Our four-month, virtual-first program is designed for early-stage innovators, helping them strengthen their business models, refine their value propositions, and build the foundation for sustainable growth and meaningful impact.

Benefits:

  • $30,000 non-dilutive stipend 
  • Partnership with youth from Headsteam’s Youth Co-Creator Club to gain insights on cultural relevance, age-appropriateness, and user experience, ensuring your solutions resonate deeply and effectively with the next generation 
  • Access to a network of expert advisors, connect with a community of founders, and engage with potential investors and capital providers 
  • Access to one-on-one and group coaching sessions with our partner, FounderWell

Participant Expectations:

  • Attend all activities, including virtual cohort and youth co-creation sessions, advisor calls, and an in-person kickoff event from July 28–30, 2026
  • Commit 2–5 hours weekly during the program, including virtual sessions, advisor network office hours, guide calls, and more
  • Embed youth voices throughout your product development
Education Health & Medicine Entrepreneurship +4 more

Educational Incentive Award Application for Children of Individuals with Thalassemia

Cooley’s Anemia Foundation Inc
Private
United States
US $500 - US $1,000
The Educational Incentive Award Application by the Cooley’s Anemia Foundation aims to support children of individuals with severe thalassemia in pursuing their educational and career aspirations. With a total funding of $10,000 for the 2025-2026 school year, awards range from $500 for two-year programs to $1,000 for higher degree studies. Eligible applicants must be diagnosed with specific thalassemia types and provide necessary documentation, including a 250-word essay detailing their educational goals.
Education - Higher Education Workforce Preparation & Job Readiness Hematological Systems +3 more

Thalassemia Patient Incentive Award

Cooley’s Anemia Foundation Inc
Private
United States
US $250 - US $2,000
The Thalassemia Patient Incentive Award, sponsored by the Cooley’s Anemia Foundation, aims to support thalassemia patients in pursuing their educational and career aspirations. Awards ranging from $250 to $2,000 will be granted to students at various academic levels, with applications due in March 2026. This initiative not only encourages academic growth but also fosters a positive outlook among patients living with thalassemia, underscoring the Foundation's commitment to improving their quality of life.
Education - Higher Education Workforce Preparation & Job Readiness Vocational & Trade Education +3 more

NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is offering access to biospecimens from the ABCD, HBCD, and PATH studies to promote research on health and disease across a lifetime. This initiative encourages projects that utilize these samples to deepen understanding of genetic and environmental influences, particularly substance exposure. Researchers can submit proposals to maximize the scientific utility of these resources, in alignment with the goals outlined under federal health regulations.
Addiction & Substance Use Disorders Drug Use Disorder Human Genome & Genetics

NALMS Achievement Awards: Jim Flynn Outstanding Corporation Award

North American Lake Management Society (NALMS)
Association/Society
North America
Unspecified amount
The Jim Flynn Outstanding Corporation Award, presented annually by NALMS, honors the corporation that has made significant contributions to advancing lake management goals. This award emphasizes the importance of facilitating information exchange, promoting public awareness of lake ecosystems, and supporting management programs at all levels. Eligible nominations can come from any individual or entity, focusing on achievements in lake and reservoir management. Notably, current NALMS board members and awards committee members are excluded from eligibility.
Limnology Freshwater Conservation Water Resource Management

Opioid Crisis Response Program Fellowship

Equal Justice Works
Private
United States
Unspecified amount
The Opioid Crisis Response Program Fellowship, offered by Equal Justice Works, addresses the opioid epidemic by mobilizing public interest lawyers to provide vital civil legal aid to underserved communities affected by Opioid Use Disorder. This two-year fellowship enables attorney fellows to advocate for clients' rights, reduce barriers to treatment, and enhance community education about legal impacts. Through collaboration with various stakeholders, the program aims to improve health outcomes and foster systemic change in the fight against this public health crisis.
Addiction & Substance Use Disorders Drug Use Disorder Legal Services +1 more

Rural Opioid Technical Assistance Centers

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Up to US $650,000
The Rural Opioid Technical Assistance Centers program aims to provide essential training and technical assistance to combat opioid and stimulant misuse in rural areas. With 10 Regional Centers and a National Coordinating Office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders. This program anticipates awarding 11 new grants to enhance community health and safety in addressing polysubstance use challenges.
Addiction & Substance Use Disorders Drug Use Disorder Rural Health Care

Barney Family Foundation Grant

Barney Family Foundation
Private
United States
US $5,000 - US $50,000
The Barney Family Foundation Grant focuses on improving early education and advancing medical research, particularly in cancer and Alzheimer’s. It supports organizations that demonstrate a clear plan to enhance children's life experiences and educational opportunities for those in grades K-8. Grants typically range from $5,000 to $50,000, prioritizing established entities while welcoming startups. Eligible applicants must have 501(c)(3) status, and the Foundation does not fund individual requests or political activities.
Education - Preschool / Early Learning Education - Middle School Education - Elementary School +2 more

Core State Injury Prevention Program (Core SIPP) (363398)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Core State Injury Prevention Program (Core SIPP) aims to enhance public health infrastructure and partnerships to prevent unintentional injuries through data-driven strategies. Focusing on key areas such as traumatic brain injury, falls among older adults, and drowning, it seeks to improve community safety by strengthening data use and fostering collaborations. This initiative supports states in identifying local injury concerns, thus promoting evidence-based prevention approaches and increasing the capacity for sustained public health actions.
Wounds & Injuries Suicide Prevention Brain Injuries

RMEF Grant Program- Hunting Heritage

Rocky Mountain Elk Foundation (RMEF)
Private
United States
Unspecified amount

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

Land / Habitat Conservation Sport Shooting Outdoor Recreation +2 more

Loene Pooler Guthrie Scholarship Fund

Benton Community Foundation
Private
United States
Unspecified amount

Loene Pooler Guthrie Scholarship Fund

The Loene P. Guthrie Scholarship fund benefits music students in Benton, Linn, and Lincoln counties who plan to engage in the teaching of piano, voice, and orchestral music.

This scholarship fund promotes the teaching of piano, voice and orchestral music by aiding music students in Benton, Linn, and Lincoln Counties who plan to engage in the teaching of piano, voice, and orchestral music. Students who will graduate from Linn, Benton, or Lincoln County high schools or graduates of those high schools currently studying music at an institution of higher learning may apply. The Linn-Benton Chapter of the Oregon Music Teachers Association reviews the applications and selects individuals to perform at an audition open to the public.

Performing Arts Music Education Symphony / Orchestra

Sun Life’s Health Access Heroes Grant Program

Sun Life Financial
Corporate
United States
US $25,000 - US $100,000
Sun Life’s Health Access Grant Program aims to enhance access to health services, specifically targeting diabetes and oral health in local communities. With funding options ranging from $25,000 to $100,000, this program supports 501(c)(3) charities focused on diabetes prevention, management, and oral health care. By fostering access to essential health services, Sun Life is committed to building healthier communities and addressing health disparities faced by underprivileged populations.
Diabetes Obesity Nutrition & Healthy Eating +1 more

NALMS Achievement Awards: Secchi Disk Award

North American Lake Management Society (NALMS)
Association/Society
North America
Unspecified amount
The NALMS Achievement Awards: Secchi Disk Award recognizes outstanding contributions to lake management by its members. NALMS aims to unite citizens, scientists, and professionals to ensure the protection and management of lakes and reservoirs. This prestigious award is open to NALMS members, with nominations encouraged from any individual or entity. However, current board and committee members are ineligible. The award celebrates those who significantly advance NALMS's goals and objectives in fostering lake ecosystem awareness and management.
Limnology Freshwater Conservation Water Resource Management

Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to support urgent research evaluating policies that impact health behaviors related to obesity. It is designed for studies that can only be performed with expedited review due to the time-sensitive nature of the research. Applications must demonstrate a compelling need for immediate funding to explore new policies or programs affecting dietary habits and physical activity, with the expectation that successful proposals will receive funding within four months.
Obesity Health Policy & Advocacy Nutrition & Healthy Eating +2 more

Grants for 501(c)(3) in Missouri Highlights

Looking for grants for 501(c)(3) in Missouri?


Read more about each grant below or start your 14-day free trial to see all grants for 501(c)(3) in Missouri recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for 501(c)(3) in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Grants for 501(c)(3) in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Grants for 501(c)(3) in Missouri over $25K in average grant size

29 Grants for 501(c)(3) in Missouri over $50K in average grant size

25 Grants for 501(c)(3) in Missouri supporting general operating expenses

100+ Grants for 501(c)(3) in Missouri supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for 501(c)(3) in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Grants for 501(c)(3) in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Grants for 501(c)(3) in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Grants for 501(c)(3) in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Grants for 501(c)(3) in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081