South Dakota Community Programs Funding via US Bancorp Foundation
South Dakota nonprofit organizations working on economic and workforce advancement, affordable housing, or community arts and culture can access funding via US Bancorp Foundation through its Community Possible Grant Program. 501(c)(3) cancer nonprofits that also address these areas, especially those led by people of color and serving U.S. Bank communities, may be eligible to apply via LOI.
US Bancorp Foundation
Costco Foundation Youth and Health Grants in South Dakota
Nonprofit organizations in South Dakota that are 501(c)(3)s and run programs for children, education, or health and human services may be eligible for monetary support. Grants from Costco Foundation help community-focused groups that can demonstrate measurable outcomes and strong collaboration. Cancer-focused nonprofits serving children or families may fit if they meet these priorities.
Costco Wholesale Corporation
Creag Foundation Grant
The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.
Creag Foundation
Youth Welfare Grants for Nonprofits from DanPaul Foundation
501(c)(3) organizations worldwide, including those in South Dakota, can apply for DanPaul Foundation grants of up to US $15,000 to support youth health, education, development, and welfare programs. Cancer-focused nonprofits serving children and youth, especially in areas like child advocacy, poverty, homelessness, or environmental health, may be eligible.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants
The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.
Draper Richards Kaplan Foundation
Tech-Enabled Social Impact Funding from Cisco
Nonprofit and NGO programs using technology for crisis response, education access, or economic empowerment, including those in South Dakota, can seek Global Impact Cash Grants to address major social challenges. Cisco Systems Foundation supports innovative, early-stage, tech-enabled solutions serving mostly economically underserved communities, with awards up to US $100,000 and a brief LOI accepted year-round.
Cisco Systems Foundation
Community Safety and Education Grants from State Farm
South Dakota 501(c)(3) nonprofits, volunteer fire companies, educational institutions, and government programs can access funding through State Farm Companies Foundation for safety, education, and community development initiatives. Cancer-focused organizations may be eligible if their programs address areas like community safety, disaster response, education, financial literacy, or neighborhood revitalization in a sustainable way.
State Farm Companies Foundation
South Dakota Health Funding via Labcorp Charitable Foundation
Health, education, and community-focused 501(c)(3) organizations in South Dakota can access funding through Labcorp Charitable Foundation to support healthcare access, food pantries, STEM programs, and related services. U.S.-based nonprofits, including those providing cancer care or support as part of broader health and welfare work, may be eligible if they align with the foundation’s three supported areas.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Youth Grants
Organizations working to improve education, children’s health, or family economic stability for urban low-income youth can apply for Michael & Susan Dell Foundation support; awards are More than US $50,000 for project work or scaling. South Dakota cancer-focused nonprofits serving children and families in poverty may be eligible if their programs fit these priorities.
Michael & Susan Dell Foundation
Humanitarian and Education Funding for Charities from Roche
Charitable organizations managing humanitarian, social development, science education, community, environmental, or arts projects in South Dakota may be eligible for funding that supports programmatic activities and community initiatives. Focused on humanitarian and social impact, Roche invites accredited charities to propose innovative, high-quality projects; cancer-focused nonprofits may qualify if their work fits these priority areas and local affiliate guidelines.
La Roche, Inc.
Health and Human Services Funding from Semnani Family Foundation
Nonprofit organizations providing health, education, or humanitarian services in South Dakota and other eligible countries can seek support for programs serving marginalized and vulnerable communities. Semnani Family Foundation provides global funding that may benefit cancer-focused nonprofits whose work overlaps with health care access, disease support, or related human and social services.
Semnani Family Foundation
Bank of America Support for Community Programs
Nonprofit 501(c)(3) organizations in South Dakota seeking support for community-focused programs can apply for funding that advances economic mobility and social progress. Bank of America Foundation supports initiatives such as basic needs, workforce development, community development, arts and culture, environment, and diversity and inclusion, which may benefit cancer-related organizations serving low- and moderate-income communities.
Bank Of America Charitable Foundation Inc
South Cancer Programs Funding via Robinson Foundation
Applications due Oct 15, 2026
South region 501(c)(3) organizations serving cancer patients or related health and family needs can access funding through Robinson Foundation for programmatic support, not capital projects. Eligible nonprofits must be over three years old, request single-year funding, and work in areas like medical assistance, children and families, poverty relief, or disaster relief, which may benefit cancer-focused services.
Robinson Foundation
Dudley T Dougherty Foundation Support for Community Services
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding can apply for flexible project support, including cancer-related initiatives, in South Dakota and beyond. Focused on positive change, the Dudley T Dougherty Foundation invites eligible groups to propose efforts that respect people, life, and the environment.
Dudley T Dougherty Foundation Inc
Basic Needs Funding for Nonprofits from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near South Dakota TJX locations that provide basic needs, youth enrichment, workforce readiness, or domestic violence safety may be eligible for TJX Foundation grants. TJX Foundation supports community programs within 15 miles of its stores, distribution centers, or offices, which can include cancer-focused nonprofits serving vulnerable families and children.
The Tjx Foundation Inc
Lawrence Foundation Support for Community Programs
Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries seeking support for environmental, human services, or related community programs in South Dakota can apply for grants of US $5,000 - US $10,000. With a mission to back these areas, Lawrence Foundation provides unrestricted operating or project funding, which may benefit cancer-focused organizations whose work fits its priorities.
Lawrence Foundation
Max and Victoria Dreyfus Foundation Grants for South Dakota Community Programs
Applications due Nov 11, 2026
Max and Victoria Dreyfus Foundation provides South Dakota nonprofits with US $1,000 - US $20,000 to support museums, cultural and performing arts, education and skills training, health facilities, environmental and wildlife protection, and other community-based programs. IRS-qualified cancer-focused organizations may be eligible if their work fits these program areas and they are based in the U.S.
Max and Victoria Dreyfus Foundation
Spark Good: Strengthening Community - Local Grants
Applications due Nov 30, 2026
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Wal-Mart Foundation
Ameriprise Financial Support for Community Vitality
Applications due Jan 15, 2027
Focused on basic needs and community vitality, this program invites U.S.-based 501(c)(3) nonprofits to apply for funding that addresses hunger, shelter, adult self-sufficiency, community development, and cultural enrichment. South Dakota cancer nonprofits that also provide services like food access, housing support, financial literacy, or workforce readiness may be eligible, especially where Ameriprise volunteers are engaged.
Ameriprise Financial
Nordstrom Community Grant
Applications due Jan 31, 2027
The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.
Nordstrom
Dr. Scholl Foundation Grants
Letter of inquiry due Feb 1, 2027
The Dr. Scholl Foundation offers grants annually to IRS 501(c)(3) organizations, primarily focusing on U.S. applicants. The foundation supports projects in education, social services, healthcare, civic and cultural initiatives, and environmental efforts. While the grant cycle runs from October 1 to March 1, it encourages innovative solutions to global challenges. Only one application per organization is accepted each year, and funding is limited to one year. Unqualified organizations, including political entities, are ineligible.
Dr Scholl Foundation
Hansen Family Foundation Humanitarian Grants in South Dakota
Applications due Mar 23, 2027
South Dakota cancer nonprofits and other 501(c)(3) organizations can access funding for humanitarian, children’s services, education, environmental work, animal welfare, arts, and basic human needs projects. Grants from Hansen Family Foundation range from US $1,000 - US $10,000 and prioritize smaller U.S.-based organizations with budgets under $1 million and overhead below 25%.
Hansen Family Foundation
Storytelling Funding for Nonprofits from Couch Foundation
Letter of inquiry due Mar 27, 2027
Cancer-focused and other eligible 501(c)(3) nonprofits in South Dakota can use this grant to develop storytelling projects that highlight their community impact. Focused on preservation, education, and wellness, the Jesse W Couch Charitable Foundation invites organizations to share transformational work through media or narrative efforts; awards more than US $50,000.
Jesse W Couch Charitable Foundation
Chick Fil A Foundation Grants for Youth
Applications due May 1, 2027
South Dakota cancer nonprofits and other 501(c)(3) organizations serving youth and families can access funding for community, education, food security, and environmental programs through Chick Fil A Foundation’s True Inspiration Awards. Grants from US $30,000 - US $350,000 support initiatives like youth development, housing, hunger relief, and environmental stewardship that benefit local communities.
Chick Fil A Foundation Inc
Pew Charitable Trusts Support for Biomedical Research
Letter of inquiry due May 13, 2027
Early-career biomedical researchers at nominated U.S. institutions can receive US $75,000 - US $300,000 to support independent, human health–related research. Grants from Pew Charitable Trusts help South Dakota cancer and oncology investigators at participating universities or medical centers fund personnel, equipment, supplies, and travel, with flexible support over four years and required annual meetings for scholars.
Pew Charitable Trusts
Partnership Awards for Nonprofits from Mutual of America Foundation
Applications due Jul 1, 2027
U.S. nonprofit organizations leading strong cross-sector partnerships, including those in South Dakota working on cancer and oncology issues, can apply for Mutual of America Foundation’s Community Partnership Award. Funding recognizes collaborative programs that measurably improve communities, demonstrate clear social impact, and offer models that can be replicated or scaled to address significant social challenges.
Mutual Of America Foundation
South Dakota Human Services Funding via Gupta Family Foundation
Applications due Jul 31, 2027
Non-sectarian human and social service nonprofits working to help disadvantaged people become self-reliant, including those in South Dakota, can apply for Gupta Family Foundation grants of US $5,000 - US $250,000. With a mission to support focused interventions and disaster relief, the foundation favors smaller 501(c)(3) organizations or qualifying foreign entities with lean operations.
Gupta Family Foundation