Best Grants for Cancer Nonprofits in South Dakota

South Dakota nonprofit organizations working on economic and workforce advancement, affordable housing, or community arts and culture can access funding via US Bancorp Foundation through its Community Possible Grant Program. 501(c)(3) cancer nonprofits that also address these areas, especially those led by people of color and serving U.S. Bank communities, may be eligible to apply via LOI.

Nonprofit organizations in South Dakota that are 501(c)(3)s and run programs for children, education, or health and human services may be eligible for monetary support. Grants from Costco Foundation help community-focused groups that can demonstrate measurable outcomes and strong collaboration. Cancer-focused nonprofits serving children or families may fit if they meet these priorities.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

501(c)(3) organizations worldwide, including those in South Dakota, can apply for DanPaul Foundation grants of up to US $15,000 to support youth health, education, development, and welfare programs. Cancer-focused nonprofits serving children and youth, especially in areas like child advocacy, poverty, homelessness, or environmental health, may be eligible.

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

Nonprofit and NGO programs using technology for crisis response, education access, or economic empowerment, including those in South Dakota, can seek Global Impact Cash Grants to address major social challenges. Cisco Systems Foundation supports innovative, early-stage, tech-enabled solutions serving mostly economically underserved communities, with awards up to US $100,000 and a brief LOI accepted year-round.

South Dakota 501(c)(3) nonprofits, volunteer fire companies, educational institutions, and government programs can access funding through State Farm Companies Foundation for safety, education, and community development initiatives. Cancer-focused organizations may be eligible if their programs address areas like community safety, disaster response, education, financial literacy, or neighborhood revitalization in a sustainable way.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

South Dakota cancer-focused nonprofits offering social services like housing, food access, legal aid, reentry, or youth development can access funding through William Randolph Hearst Foundation for program, capital, or general support. U.S.-based 501(c)(3) organizations with audited expenses over $2 million and demonstrated, scalable impact may receive more than US $100,000 to advance economic independence and strengthen families.

Health, education, and community-focused 501(c)(3) organizations in South Dakota can access funding through Labcorp Charitable Foundation to support healthcare access, food pantries, STEM programs, and related services. U.S.-based nonprofits, including those providing cancer care or support as part of broader health and welfare work, may be eligible if they align with the foundation’s three supported areas.

Organizations working to improve education, children’s health, or family economic stability for urban low-income youth can apply for Michael & Susan Dell Foundation support; awards are More than US $50,000 for project work or scaling. South Dakota cancer-focused nonprofits serving children and families in poverty may be eligible if their programs fit these priorities.

Nonprofit organizations providing health, education, or humanitarian services in South Dakota and other eligible countries can seek support for programs serving marginalized and vulnerable communities. Semnani Family Foundation provides global funding that may benefit cancer-focused nonprofits whose work overlaps with health care access, disease support, or related human and social services.

With a mission to support charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides South Dakota 501(c)(3) organizations with funding for programs that advance general welfare. Cancer and oncology nonprofits may be eligible if funds are used within the U.S. and the organization meets federal and, if applicable, California tax-exempt requirements.

Nonprofit 501(c)(3) organizations in South Dakota seeking support for community-focused programs can apply for funding that advances economic mobility and social progress. Bank of America Foundation supports initiatives such as basic needs, workforce development, community development, arts and culture, environment, and diversity and inclusion, which may benefit cancer-related organizations serving low- and moderate-income communities.

Early-career biomedical researchers at nominated U.S. institutions can receive US $75,000 - US $300,000 to support independent, human health–related research. Grants from Pew Charitable Trusts help South Dakota cancer and oncology investigators at participating universities or medical centers fund personnel, equipment, supplies, and travel, with flexible support over four years and required annual meetings for scholars.

South region 501(c)(3) organizations serving cancer patients or related health and family needs can access funding through Robinson Foundation for programmatic support, not capital projects. Eligible nonprofits must be over three years old, request single-year funding, and work in areas like medical assistance, children and families, poverty relief, or disaster relief, which may benefit cancer-focused services.

Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding can apply for flexible project support, including cancer-related initiatives, in South Dakota and beyond. Focused on positive change, the Dudley T Dougherty Foundation invites eligible groups to propose efforts that respect people, life, and the environment.

Nonprofit 501(c)(3) organizations near South Dakota TJX locations that provide basic needs, youth enrichment, workforce readiness, or domestic violence safety may be eligible for TJX Foundation grants. TJX Foundation supports community programs within 15 miles of its stores, distribution centers, or offices, which can include cancer-focused nonprofits serving vulnerable families and children.

Nonprofit 501(c)(3) organizations, public schools, and libraries seeking support for environmental, human services, or related community programs in South Dakota can apply for grants of US $5,000 - US $10,000. With a mission to back these areas, Lawrence Foundation provides unrestricted operating or project funding, which may benefit cancer-focused organizations whose work fits its priorities.

U.S. 501(c)(3) organizations seeking support for arts, education, social justice, health, or ethical journalism programs, including cancer-related work, can apply for the Cowles Charitable Trust’s grants of up to US $10,000. Nonprofits in South Dakota may be eligible, though the trust primarily favors projects in Downstate New York and South Florida and welcomes general operating support requests.

Focused on basic needs and community vitality, this program invites U.S.-based 501(c)(3) nonprofits to apply for funding that addresses hunger, shelter, adult self-sufficiency, community development, and cultural enrichment. South Dakota cancer nonprofits that also provide services like food access, housing support, financial literacy, or workforce readiness may be eligible, especially where Ameriprise volunteers are engaged.

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

The Dr. Scholl Foundation offers grants annually to IRS 501(c)(3) organizations, primarily focusing on U.S. applicants. The foundation supports projects in education, social services, healthcare, civic and cultural initiatives, and environmental efforts. While the grant cycle runs from October 1 to March 1, it encourages innovative solutions to global challenges. Only one application per organization is accepted each year, and funding is limited to one year. Unqualified organizations, including political entities, are ineligible.

Nonprofit 501(c)(3) organizations improving economic stability, health, or disaster relief in South Dakota communities where O’Reilly Auto Parts operates can seek project, operating, or capital support. Grants from O'Reilly Automotive Foundation help community-focused groups addressing poverty, workforce readiness, health and social services, or emergency relief that may also serve cancer patients and their families.

South Dakota cancer nonprofits and other 501(c)(3) organizations serving youth and families can access funding for community, education, food security, and environmental programs through Chick Fil A Foundation’s True Inspiration Awards. Grants from US $30,000 - US $350,000 support initiatives like youth development, housing, hunger relief, and environmental stewardship that benefit local communities.

U.S. nonprofit organizations leading strong cross-sector partnerships, including those in South Dakota working on cancer and oncology issues, can apply for Mutual of America Foundation’s Community Partnership Award. Funding recognizes collaborative programs that measurably improve communities, demonstrate clear social impact, and offer models that can be replicated or scaled to address significant social challenges.

Non-sectarian human and social service nonprofits working to help disadvantaged people become self-reliant, including those in South Dakota, can apply for Gupta Family Foundation grants of US $5,000 - US $250,000. With a mission to support focused interventions and disaster relief, the foundation favors smaller 501(c)(3) organizations or qualifying foreign entities with lean operations.