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Best Grants for 501(c)(3) in South Carolina

Find the perfect Grants for 501(c)(3) in South Carolina on Instrumentl. 9,000+ Grants for 501(c)(3) in South Carolina in the United States.

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$2.62B

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$5K

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9,000+ grants
$2.62B total
$5K median

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9,451 Results based on applied filters

The Linda and Billy Beale Scholarship

The Community Foundation of Rappahannock River Region, Inc
Private
United States
US $1,000

The Community Foundation of the Rappahannock River Region

The Community Foundation is a devoted advocate for the vitality and well-being of the Rappahannock River Region. We are a 501(c)(3) nonprofit that manages and distributes charitable giving in the counties of Stafford, Spotsylvania, King George, and Caroline, and the City of Fredericksburg.

Scholarships

One of The Community Foundation’s strategies for preserving and growing the quality of life in our region is supporting higher education for area students. Generous individuals and families, companies and organizations establish endowed scholarship funds and the proceeds from these funds benefit deserving students. Donors work with foundation staff to determine appropriate criteria for each fund. The Community Foundation currently administers more than fifty scholarship funds.

Linda and Billy Beale Scholarship

The Linda and Billy Beale Scholarship Fund was created to support charitable projects in the community that has been home to their family for many years. Friends and colleagues know Linda and Billy as individuals who are deeply engaged in the fabric of the region – and especially Caroline County – through the business community, through their civic and social lives, and through their family’s involvement in their church and schools.

When thinking about a focal point for their charitable giving through this scholarship fund, the Beale’s were drawn to the school athletic “families” that have meant so much to them and their children over the years. Billy served as assistant baseball coach from 1999 to 2003 and Linda served as assistant volleyball coach from 1998 to 2006. The family also has history of involvement with Caroline Little League that began when their son played t-ball in the 1980’s and continued through their daughter’s service as a board member as an adult. The Beale's continue to show their support by participating in Little League special events today.

Education - Higher Education Education - High School Academic Scholarship Programs

Two Joes Scholarship

Cattaraugus Region Community Foundation
Private
United States
Unspecified amount

Two Joes Scholarship

This fund, named for two local community-minded businessmen, Joe DeRose and Joe Sgro, will support a scholarship for students in Cattaraugus County interested in pursuing technology-, marketing and communications- or business-related degrees.

Education - Higher Education Career / College Preparation Business Education

St Joseph School District Foundation Tarpley, Bill Scholarship

Community Foundation Of Northwest Missouri
Private
United States
More than US $300

Community Foundation of Northwest Missouri

The Community Foundation of Northwest Missouri Inc. was established in 2009 as a 501(c)3 public charity to help donors support their favorite charities while receiving maximum tax advantage.

We serve as a vehicle for charitable giving, helping donors give to the causes they care about. Donor gifts will strengthen nonprofits increasing programs and services. Individuals and organizations are encouraged to establish a fund with us. 

St Joseph School District Foundation Tarpley, Bill Scholarship

This fund was established in honor of Bill Tarpley, who served as Principal of Central High School by his family and friends. The fund provides graduating seniors with a learning disability an opportunity to attend vocational school or college.

Guidelines:

  • One scholarship will be awarded on a one-time basis and disbursed in August.

Amount:

  • No less than $300 depending on available funds.
Learning Disabilities Vocational & Trade Education Education - Higher Education

Psoriatic Arthritis/Ankylosing Spondylitis Research Grant

Arthritis National Research Foundation
Private
United States
Up to US $250,000
The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.
Arthritis

OAR Community Grant

Organization For Autism Research
Private
United States
US $1,000 - US $15,000
The OAR Community Grant aims to enhance the quality of life for autistic individuals by funding community-led projects that address physical health and support services. Grants ranging from $1,000 to $15,000 are available for initiatives designed to produce practical tools and resources. Eligible applicants include family members, autistic individuals, and community organizations committed to improving the lives of those affected by autism. Projects should be innovative, publicly accessible, and focus on priority topics such as health systems and community services.
Autism

Alkermes Medical Education Grants

Alkermes
Corporate
United States
Unspecified amount
Alkermes Medical Education Grants support educational initiatives aimed at enhancing patient care through continuing medical education. Proposals are invited for activities related to schizophrenia, bipolar disorder, narcolepsy, and idiopathic hypersomnia. Funding is available for various CME formats, focusing on practical training and understanding treatment complexities. Eligible applicants include U.S.-based organizations that are either non-profit or accredited CME providers. This initiative prioritizes innovative strategies to improve healthcare outcomes and knowledge dissemination.
Addiction & Substance Use Disorders Mental Health & Psychiatric Diseases Sleep

William A. Brookshire Foundation Scholarship

Greater Houston Community Foundation
Private
United States
US $5,500 - US $15,000

Welcome to the Greater Houston Community Foundation Scholarship Application Site!   

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Scholarship Application Info:  

Greater Houston Community Foundation administers over 60 different scholarship programs, each with differing eligibility requirements. Eligibility for some scholarships may be dependent on employment, course of study, high school, or college. 

William A. Brookshire Foundation Scholarship

The William A. Brookshire Foundation Scholarship benefits dependents of S&B Engineers and Constructors employees.

About the Scholarship Award:

Multiple scholarships awarded for the 2026-27 academic year. Award amount varies by college/degree type:

  • Bachelor's or Graduate Degree: Up to $15,000
  • Associate's Degree: $5,500
  • Students may reapply as long as they meet eligibility requirements

What can this scholarship be used for?

The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses.

Are there any requirements I must meet if I am selected as a scholarship recipient?

  • Recipients must attend an accredited university, community college, or trade school in the United States.
  • Recipients must enroll in the following hours for both the fall and spring semesters (or be enrolled full-time according to your school if it is on a different system) unless in the last semester prior to graduation
    • Minimum of 12 hours per semester for undergraduate students
    • Minimum of 9 hours per semester for graduate students
  • Recipients must submit college enrollment information online through GHCF Scholar the summer before the academic year begins. This information is required in order for the scholarship check to be mailed to the student's college. Instructions will be included in the student's award letter.
Education - Higher Education Education - High School Academic Scholarship Programs

McLaughlin, Delbert & Mary Teaching Scholarship

Community Foundation Of Northwest Missouri
Private
United States
US $500 - US $750

Community Foundation of Northwest Missouri

The Community Foundation of Northwest Missouri Inc. was established in 2009 as a 501(c)3 public charity to help donors support their favorite charities while receiving maximum tax advantage.

We serve as a vehicle for charitable giving, helping donors give to the causes they care about. Donor gifts will strengthen nonprofits increasing programs and services. 

McLaughlin, Delbert & Mary Teaching Scholarship

This fund was established in memory of Delbert and Mary McLaughlin by their son, Bill McLaughlin to provide academic scholarships to graduating seniors of the St. Joseph School District pursing a degree in Education.

Education - Higher Education Medical Education & Professional Training Agricultural Education

Accelerating the Development of Combined CGM–Pump Devices

Breakthrough T1D ( Formally JDRF International)
Private
United States
Up to US $900,000

Accelerating the Development of Combined CGM–Pump Devices

A combined continuous glucose monitor (CGM) and insulin pump device represents an innovative approach to simplifying diabetes management by integrating two essential technologies into a single device. This approach has the potential to improve quality of life for people with type 1 diabetes (T1D) by reducing the burden associated with wearing and managing multiple devices.

Despite this promise, the development of combined CGM–pump devices presents technical and commercialization challenges. These include the need for further advances in device compatibility and lifespan, system reliability, and scalable manufacturing, while maintaining affordability and broadaccessibility. In addition, a potential insulin dilution effect may require adjustment of the CGM algorithm.

Breakthrough T1D invites applications for research and development projects that address key technical, clinical, and translational challenges related to combined CGM–pump devices, with the goal of accelerating their development and improving outcomes for people living with T1D.

In response to this announcement, applications may request up to a total of $900,000 USD for up to three years. 

Diabetes

GBA1 Parkinson's Disease Research Catalyst Program

Michael J Fox Foundation For Parkinsons Research
Private
Canada, United Kingdom +1 more
Up to US $300,000

GBA1 Parkinson's Disease Research Catalyst Program

The GBA1-PD Research Catalyst Program seeks to build a deeper, globally integrated understanding of GBA1-associated Parkinson’s disease by aligning efforts across geographies and maximizing the value of shared datasets and research assets. Funding will support hypothesis- driven projects with an emphasis on integrative, cross-cohort analyses and the systematic characterization and standardization of models to enable broad use by the research community.

Funding

Duration: 12 to 24 months

Award Amount: Up to $300,000. Requested support should be commensurate with work proposed.

These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs. 

Parkinson’s Disease

Progress, Accomplishment, Thriving, Hope (PATH) Scholarship

Ellucian Foundation
Private
Australia, Canada +8 more
US $1,500 - US $25,000
The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.
Education - Higher Education Educational Access & Equity Academic Scholarship Programs

Orthopedic Physical Therapy Research Grant

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Orthopaedic Physical Therapy Research Grant, funded by the Foundation for Physical Therapy Research, aims to support innovative research that optimizes movement and enhances societal health. With a commitment to addressing health disparities, the foundation will award $40,000 for one or two years to promising researchers. This initiative not only strengthens the physical therapy profession but also contributes to the growing evidence base that underscores the value of physical therapy in various healthcare settings.
Physical Therapy Musculoskeletal Diseases

Towsley Foundation Grants

Harry A. & Margaret D. Towsley Foundation
Private
United States
More than US $250,000
The Towsley Foundation Grants support initiatives that enhance community welfare and sustainability, focusing on diverse fields such as education, health, and the arts within Michigan. With a commitment to effective philanthropy, the foundation prioritizes projects that demonstrate creativity and strategic impact. Eligible organizations must operate in Michigan and adhere to specific funding guidelines, fostering financial sustainability. Grants are allocated based on project merit and organizational capacity, reinforcing the foundation's mission to improve lives through thoughtful partnerships.
Art & Culture Civic Affairs Community Development & Revitalization +4 more

Aim High Grant Program: One-Year Grants

New York Life Foundation
Corporate
United States
US $20,000
The Aim High Grant Program offers one-year grants of $20,000 to support out-of-school time programs for middle school youth. Funded by the New York Life Foundation, this initiative aims to enhance students' transition to high school by providing essential skills and guidance. Programs must demonstrate effective engagement strategies and serve low-income communities. This grant represents a vital investment in the future of young people, helping them develop academically, socially, and emotionally.
After School / Summer Educational Programs Education - Middle School

MDCPSS Early Career Achievement

Society of Toxicology
Association/Society
United States
Unspecified amount

Society of Toxicology

Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology. SOT operates under four guiding principles:

  • Serving the needs of the scientific discipline and our members to enhance human, animal, and environmental health.
  • Life-long learning and intellectual scientific stimulation.
  • Diversity of representation in all activities of the Society.
  • Integrity.

MDCPSS Early Career Achievement Award

Description

The MDCPSS Early Career Achievement Award recognizes the research accomplishments of young scientists in the early stages of their careers who have demonstrated excellence in toxicological research related to medical devices and/or combination products.

Award Categories

Up to two award recipients will be selected:

  • One undergraduate or graduate student
  • One postdoctoral fellow or early-career scientist (≤5 years post-graduation)

Award Recognition

  • Each recipient will receive a plaque and a monetary award to support travel to the SOT Annual Meeting.
  • Awardees will be recognized at the MDCPSS Reception and invited to give a 5-minute overview presentation of their work.

Environmental Chemistry & Toxicology

ECF of Boeing Company: South Carolina Chapter

Employees Community Fund Of The Boeing Company
Private
Berkeley County, South Carolina, Charleston County, South Carolina +1 more
Unspecified amount
Employees Community Fund (ECF) of The Boeing CompanyOne of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has been empowering employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites- provide combined employee donations to nonprofits in their communities through ECF grants.Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.South Carolina ChapterThe Employees Community Fund of Boeing (ECF) is a unique employee managed giving program that allows employees to make a positive difference in the communities where they live and work. ECF is an employee run non-profit managed by chapter Grantmaking committees (CGC) and governance board with each chapter having separate funding priorities and focus areas depending on local needs.ECF Focus The South Carolina ECF Chapter Grantmaking committee awards grants to non-profits that align to the following five focus areas: Arts & Culture, Civic, Education, Environment and Health & Human Services.Grants must support funding in Berkeley, Charleston or Dorchester counties, align to the ECF focus areas and all nonprofits who previously received grant awards must submit an impact report with the grant request that describes the progress made towards planned outcomes along with the tangible benefits to the community.
Civic Engagement & Education Art & Culture Education +3 more

SABIC Innovative Plastics Scholarship

Posey County Community Foundation
Association/Society
United States
US $1,120
The SABIC Innovative Plastics Scholarship supports the children of employees at the Mt. Vernon, Indiana facility, providing financial aid for post-secondary education. Eligible students include graduating seniors from any U.S. high school who are dependents of active employees. Selection is based on academic performance, leadership, and community involvement. Applicants must also submit an essay detailing their goals and achievements, along with an official grade transcript. This scholarship fosters educational advancement for employee families.
Education - Higher Education Academic Scholarship Programs College Success / Persistence

Laine - Casey Laine Armed Services Scholarship

Coastal Bend Community Foundation
Private
United States
US $100 - US $16,000
The Laine - Casey Laine Armed Services Scholarship, established to honor Lieutenant Casey Laine Swakon, supports students from the Coastal Bend area who have participated in JROTC or are part of ROTC programs. Eligible candidates include high school seniors, current college students, and veterans. Applicants must maintain a minimum GPA of 2.5 and complete at least 12 credit hours per semester, ensuring they are well-prepared for their academic pursuits.
Military & Veterans Services Academic Scholarship Programs College Success / Persistence

The Alice M. Ditson Fund: Recording Projects

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund supports recording projects that aim to document and promote the music of younger, lesser-known American composers. The fund prioritizes living composers of classical concert music, especially those in the early stages of their careers, while also recognizing established composers who deserve greater visibility. Eligible applicants include organizations with a fiscal sponsor or non-profit status, and projects must involve significant contemporary American music.
Classical Music

STEM and Youth Leadership Grants

H.B. Fuller Company Foundation
Private
Caribbean, Central America +8 more
US $10,000 - US $25,000
The Minnesota STEM and Youth Leadership Grants, offered by the H.B. Fuller Company Foundation, focus on empowering young individuals through STEM education and leadership development. These grants are intended for tax-exempt organizations that serve communities near H.B. Fuller facilities, aiming to address racial inequities in education and employment. The initiative underscores the company's commitment to community support and creating opportunities for youth to thrive in science, technology, engineering, and mathematics fields.
Environmental Education Youth Development & Leadership STEM / STEAM Education

PLTW Launch - New Program (Ardagh Group)

Project Lead The Way Inc
Private
Cook County, Illinois, DeSoto County, Mississippi +7 more
US $10,000
The PLTW Launch program, supported by Ardagh Group, aims to enhance education in local communities over the next decade. This initiative is set to benefit over 500,000 PreK-12 students and provide exceptional training to more than 5,000 teachers across 2,000 U.S. schools. As a global supplier of sustainable packaging solutions, Ardagh is committed to fostering educational opportunities that empower communities and promote equal access to quality education.
Teacher Development & Training Education - K through 12 Education - Preschool / Early Learning +1 more

Greater Tindall Neighborhood Scholarship Fund

Community Foundation of Central Georgia
Private
United States
US $2,000
The Greater Tindall Neighborhood Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support residents of Tindall Heights pursuing post-secondary education. It offers $2,000 per recipient, renewable for up to four years. Eligible applicants must demonstrate financial need, maintain a minimum 2.0 GPA, and enroll full-time at an accredited institution. The scholarship fosters educational growth and community development, ensuring that residents have the necessary resources to succeed in their academic endeavors.
Education - Higher Education Education - High School Academic Scholarship Programs

Monticello College Foundation Grant

Monticello College Foundation
Private
United States
Unspecified amount
The Monticello College Foundation Grant supports projects that promote female education. Eligible applicants include professional educational associations and accredited colleges in the Midwest. The foundation prioritizes innovative proposals that demonstrate significant need. Grants are given for a single fiscal year, with ongoing requests requiring annual re-application. Proposals should be submitted by August 31 for fall consideration and by February 28 for spring review. Funding is not available for direct grants to individuals or capital purposes.
Women's Rights & Equality Educational Access & Equity

Asia: Responsive Grants

Henry Luce Foundation
Private
Brunei Darussalam, Cambodia +16 more
Unspecified amount
The Henry Luce Foundation's Asia: Responsive Grants program supports initiatives that enhance understanding of East and Southeast Asia. With a focus on academic research, cultural exchange, and public education, the program seeks to promote collaboration between American and Asian institutions. Grants are awarded primarily to U.S.-based non-profits, fostering innovative teaching, resource development, and policy engagement, while prioritizing projects that bridge diverse disciplines and geographic divides.
Asian Art Asian / Pacific Island Culture & Heritage

Lewis G. and Margaret R. Curtis Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Lewis G. and Margaret R. Curtis Scholarship

This scholarship has been made possible by the generosity of Lewis and Margaret, who established the Lewis G. and Margaret R. Curtis Scholarship of the Community Foundation for Muskegon County. Margaret Curtis wished to establish two scholarships; one for females pursuing careers in nursing or health care careers and the other for a male pursuing a vocational, technical or trade career scholarship. Mrs. Curtis, a nurse in the area, provided for this fund in her will in memory of her husband and herself. She stated that the income be used to award scholarships in two fields, nursing and vocational training.

Education - Higher Education Nursing Vocational & Trade Education

Clinical Trials in Organ Transplantation in Children and Adults

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.
Infectious & Parasitic Diseases Organ And Tissue Banks

Grants for 501(c)(3) in South Carolina Highlights

Looking for grants for 501(c)(3) in South Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for 501(c)(3) in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for 501(c)(3) in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Grants for 501(c)(3) in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Grants for 501(c)(3) in South Carolina over $25K in average grant size

40 Grants for 501(c)(3) in South Carolina over $50K in average grant size

32 Grants for 501(c)(3) in South Carolina supporting general operating expenses

100+ Grants for 501(c)(3) in South Carolina supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for 501(c)(3) in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Grants for 501(c)(3) in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Grants for 501(c)(3) in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Grants for 501(c)(3) in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for 501(c)(3) in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081