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Best St. Louis city Grants for Nonprofits in Missouri

Discover active funding opportunities in St. Louis city Grants for Nonprofits. 36,000+ grants are available for a wide range of missions and programs with additional grants in St. Louis County, Jackson County, and St. Charles County.

9,000+

Available grants

$2.60B

Total funding

$5K

Median grant

9,000+ grants
$2.60B total
$5K median

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9,436 Results based on applied filters

DoW Bone Marrow Failure, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.
Skeletal Diseases Myeloma

DoW Bone Marrow Failure, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.
Skeletal Diseases Myeloma

DoW Rare Cancers Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $490,000
The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.
Cancer / Oncology

DoW Rare Cancers Resource and Community Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,120,000
The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.
Cancer / Oncology

DoW Joint Warfighter Medical, Military Medical Research and Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $1,400,000 - US $3,000,000
The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.
Military Operations

DoW Bone Marrow Failure, Resource Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.
Skeletal Diseases Myeloma

State Cyber Crime Grant (SCCG) Program

Missouri Department of Public Safety
State/Local Government
Missouri
Unspecified amount

The goal of State Cyber Crime Grant (SCCG) is to make funds available to reduce internet sex crimes against children and improve public safety for children through investigations, forensics, and prevention. This program provides support for the continued operation of multi jurisdictional law enforcement cybercrime task forces. 

Child Welfare Services Crime Victim Services

Paul Coverdell National Forensic Science (Coverdell) Improvement Grant

Missouri Department of Public Safety
State/Local Government
Missouri
Unspecified amount

This project will directly improve the quality and timeliness of forensic science services provided to the law enforcement community of Missouri by increasing examiner proficiency, competency, knowledge, skills, and abilities. This project involves all of Missouri’s crime laboratories – those operated by units of local government and those operated by the state.

Forensics

Missouri Edward Byrne Memorial Justice Assistance Grant

Missouri Department of Public Safety
State/Local Government
Missouri
Unspecified amount

The DPS’ strategic priorities encompass several key initiatives including; building relationships with external stakeholders, identifying hazards and threats to public safety, maintaining sufficient capacities to perform statutorily required responsibilities and utilizing federal and state programs to protect, as well as provide impactful service to Missouri citizens. The grant opportunity provides resources to combat drug related crimes. 

Community / Public Safety Police & Law Enforcement

Minority Police Officer Recruitment and Retention Grant (MPORR)

Missouri Department of Public Safety
State/Local Government
Missouri
Unspecified amount

The purpose of the Minority Police Officer Recruitment and Retention (MPORR) project is to support minority police officer recruitment and retention programs located in a city not within a county with such program being administered and overseen by an African-American police officer association that supports efforts in reducing crime in a city not in a county and county with more than one million inhabitants. 

Police & Law Enforcement

DoW Kidney Cancer, Academy of Kidney Cancer Investigators – Early-Career Scholar Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The DoW Kidney Cancer Early-Career Scholar Award is a unique initiative by the Academy of Kidney Cancer Investigators, established in FY19. It aims to foster innovative kidney cancer research through a mentoring program that pairs early-career scholars with experienced mentors. This program not only enhances research capabilities but also builds a robust network of kidney cancer researchers. By supporting promising scholars, the initiative aspires to advance the field and improve treatment outcomes for kidney cancer patients.
Cancer / Oncology Kidney Diseases

DoW Parkinson’s, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.
Parkinson’s Disease

Fiscal Year (FY) 2027 Department of the Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
United States
US $450,000 - US $525,000
The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.
Engineering Education - Higher Education Science +1 more

DoW Kidney Cancer, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $900,000
The FY26 Kidney Cancer Research Program's Idea Development Award supports innovative research that enhances understanding of kidney cancer, aimed at improving patient outcomes. Proposals should feature a strong hypothesis and a detailed research plan, with team members experienced in kidney cancer research. A unique aspect is the Partnering Principal Investigator option, fostering collaboration between two investigators, ensuring comprehensive project development while allowing for distinct submissions. This award emphasizes impactful partnerships to drive advancements in the field.
Cancer / Oncology Kidney Diseases

DoW Parkinson’s, Early Investigator Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,000,000
The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.
Parkinson’s Disease

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

BlackRock Future Builders Grant

Blackrock Foundation Inc
Private
Puerto Rico, United States +1 more
US $500,000 - US $1,000,000

About BlackRock

We’re a global asset manager and technology provider dedicated to helping more and more people experience financial well-being. We help millions of people invest to build savings that serve them throughout their lives. The BlackRock Foundation which funds and partners with organizations that strengthen financial security for more people,

BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

  • Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
  • Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.
Workforce Preparation & Job Readiness Apprenticeship & Internship Programs Vocational & Trade Education +2 more

Medical Student Service Leadership Project Grant​​​

Alpha Omega Alpha Honor Medical Society
Private
United States
Up to US $9,000

AΩA is committed to preparing future leaders in medicine and health care. Leadership is about making a positive difference and can be developed through education, observation, experience, and by working with leader mentors. Service learning provides excellent opportunities for students to develop as servant leaders. Only one team from each school may be nominated.

Medical Education & Professional Training

National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional) (362722)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Centers for Biomedical Imaging and Bioengineering (NCBIB) provide critical resources for biomedical imaging and bioengineering research. This funding opportunity supports the development of innovative technologies tailored to the needs of basic, translational, and clinical researchers. NCBIB facilitates technology access, training, and dissemination, enhancing collaboration and advancing the field. Applications are encouraged to foster advancements that address complex biomedical challenges.
Bioengineering Biomedical Imaging

Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP) aims to strengthen viral hepatitis surveillance and prevention efforts across the United States. By enhancing outbreak response capabilities and promoting testing and treatment in high-impact settings, this initiative seeks to improve public health outcomes. Key components include partnerships, strategic planning, and perinatal hepatitis C programs, ultimately striving for better access to prevention and treatment services, aligning with CDC priorities.
Liver Disease Hepatitis B

Evelyn Manning Potter and Vivian Grove Strunk Memorial Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Evelyn Manning Potter and Vivian Grove Strunk Memorial Scholarship, administered by the Community Foundation of Washington County, MD, supports students pursuing careers in the administrative professional field. Established in memory of two dedicated professionals, this scholarship aims to provide financial assistance to qualified individuals, promoting their educational and career aspirations. The foundation offers over 100 scholarships, reflecting its commitment to enhancing the community's quality of life and supporting local talent.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Carol D. Garling Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Carol D. Garling Scholarship, established by Carol D. Garling, provides financial assistance to students pursuing a post-secondary education who have completed at least 30 credit hours at an accredited institution. Offered by the Community Foundation of Washington County, MD, this scholarship is part of a larger initiative to support local students and promote educational advancement within the community. Applications are accepted annually from January to April 1st, encouraging both high school graduates and non-traditional students.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Bill Dorsey Memorial Scholarship Fund for Barbara Ingram School for the Arts

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Bill Dorsey Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, offers scholarships to students at the Barbara Ingram School for the Arts (BISFA). Designed for rising sophomores, juniors, and seniors, this fund helps cover costs related to their arts discipline. Applications are available in the Fall, supporting the foundation's mission to enhance educational opportunities for local students and nurture their artistic talents.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Hagerstown Garden Club Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +2 more

WaterSMART Cooperative Watershed Management Program

US Department of the Interior: Bureau of Reclamation (USBR)
Federal Government
American Samoa, Guam +4 more
US $50,000 - US $300,000
The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.
Habitat & Ecosystem Restoration Water Resource Management

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

St. Louis city Grants for Nonprofits Highlights

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Grant Insights : St. Louis city Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

94 St. Louis city grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

15 St. Louis city grants for nonprofits over $25K in average grant size

6 St. Louis city grants for nonprofits over $50K in average grant size

21 St. Louis city grants for nonprofits supporting general operating expenses

77 St. Louis city grants for nonprofits supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

4,000+ Grants on Instrumentl focused on Academic Scholarship Programs

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for St. Louis city grants for Nonprofits?

Most grants are due in the fourth quarter.

Q1
23.6%
Q2
26.2%
Q3
20.9%
Q4
29.3%

Typical Funding Amounts

What's the typical grant amount funded for St. Louis city Grants for Nonprofits?

Grants are most commonly $10,000.

$500 $500 Min.
$10,000 $10 K Median
$29,618 $29.6 K Average
$775,000 $775 K Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in St. Louis city Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the St. Louis city Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for St. Louis city Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

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