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Best St. Louis city Grants for Nonprofits in Missouri

Discover active funding opportunities in St. Louis city Grants for Nonprofits. 36,000+ grants are available for a wide range of missions and programs with additional grants in St. Louis County, Jackson County, and St. Charles County.

9,000+

Available grants

$2.60B

Total funding

$5K

Median grant

9,000+ grants
$2.60B total
$5K median

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9,442 Results based on applied filters

Shelter Operations Support (SOS) Grant Program

Missouri Housing Development Commission
State/Local Government
Missouri
Up to US $500,000
The Shelter Operations Support (SOS) Grant Program aims to enhance emergency shelter operations in Missouri, prioritizing assistance to programs that serve veterans. It is designed for established non-profits and community organizations with a track record of at least two years. The program provides operating and administrative funds to ensure safe temporary housing for residents facing crises, while maintaining compliance with funding restrictions and eligibility criteria.
Supportive Housing & Shelters Homelessness Services

Abbey Mural Prize

National Academy of Design
Private
American Samoa, Guam +4 more
US $10,000 - US $40,000
The Abbey Mural Prize, established in 1932, supports the creation and restoration of public murals across the United States. This prestigious award, administered by the National Academy of Design since 1940, emphasizes projects that enhance community engagement and social activism through art. Grants typically range from $10,000 to $40,000, with a total annual funding cap of $125,000. Eligible applicants include artists, architects, and nonprofit organizations committed to impactful mural projects.
Public / Community Art

UEF Grant Program

United Engineering Foundation Inc
Private
United States
Up to US $800,000
The UEF Grant Program, offered by the United Engineering Foundation, supports innovative projects that enhance the engineering profession and public welfare. With an annual budget of nearly $800,000, the program awards 5 to 10 grants each year. Eligible applicants must be U.S.-based organizations with 501(c)(3) status. Preference is given to interdisciplinary proposals that engage the community and integrate various engineering fields, fostering collaboration and addressing important societal issues.
Engineering

Smart Growth Grants: Level 1, 2 & 3

National Association Of Realtors
Private
United States
Up to US $15,000
The Smart Growth Grants program, managed by the National Association of Realtors, aims to enhance community development through educational initiatives aligned with Smart Growth Principles. Available in three levels, the grants support REALTOR Associations in promoting sustainable land use, community planning, and stakeholder engagement. Maximum awards range from $3,000 to $15,000, depending on the grant level. Note that the program is currently not accepting applications for 2025 and will reopen in January 2026.
Real Estate & Housing Community Development & Revitalization Urban Planning

Progress, Accomplishment, Thriving, Hope (PATH) Scholarship

Ellucian Foundation
Private
Australia, Canada +8 more
US $1,500 - US $25,000
The PATH Scholarship, established by the Ellucian Foundation in 2020, aims to support higher education institutions in assisting students facing financial hardships. With over $2.9 million awarded, it has benefited more than 3,100 students. Eligible institutions can receive grants ranging from $10,000 to $25,000, with individual awards up to $1,500. This initiative encourages public two-year colleges, particularly Minority Serving Institutions, to apply and adapt award criteria to meet the needs of their students.
Education - Higher Education Educational Access & Equity Academic Scholarship Programs

BRAIN Initiative Advanced Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) (347532)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The BRAIN Initiative Advanced Postdoctoral Career Transition Award (K99/R00) aims to enhance diversity in neuroscience by supporting talented postdoctoral researchers from various backgrounds. This program facilitates their transition to independent faculty positions, providing essential NIH research support to help launch competitive research careers. Applications are due in February, June, and October for standard grants, and in March, July, and November for renewals.
Neuroscience Diversity, Equity & Inclusion

Lots of Compassion Grant

KidsGardening
Private
American Samoa, Guam +4 more
US $20,000
The Lots of Compassion Grant, supported by KidsGardening and Mrs. Meyer’s Clean Day, aims to transform vacant urban lots into thriving community gardens. By providing $20,000 to each of the 10 selected grantees, the initiative focuses on empowering under-resourced communities, fostering social connections, and enhancing mental health. The grant prioritizes organizations that involve diverse participants and demonstrate significant community impact, ensuring that the gardens not only flourish but also cultivate kindness and compassion.
Horticulture & Gardening Greening & Beautification

Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,500,000
This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.
Drug Use Disorder Addiction & Substance Use Disorders Pharmacology +1 more

B.W. Bastian Foundation Grant

B.W. Bastian Foundation
Private
United States
US $100 - US $15,000
The B.W. Bastian Foundation Grant supports organizations committed to equality for all Americans, including the LGBTQ+ community. Grants typically range from $100 to $15,000, and applicants must have 501(C)3 tax status. Funding is primarily for projects in the Intermountain West and may include general operating support or specific programs. Organizations should first inquire before applying, especially if requesting more than previous grants. The foundation does not fund individuals or lobbying efforts.
Racial / Ethnic Justice & Rights Social Justice / Human Rights Disability Rights & Justice +5 more

SPRK-ing Interest in Computer Science

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Guam +6 more
Unspecified amount in in-kind support
The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.
Computer Science & Engineering STEM / STEAM Education

Infrastructure Capacity for Biological Research (347679)

National Science Foundation (NSF)
Federal Government
United States
US $25,000 - US $1,200,000
The Infrastructure Capacity for Biological Research Program, supported by the National Science Foundation, aims to enhance research capabilities across various biological disciplines. This program encourages proposals for developing and improving research tools and services in areas such as Cyberinfrastructure and Biological Collections. It also welcomes planning activities to foster collaboration among researchers. Projects must ensure broad accessibility and significant scientific outcomes for the wider research community.
Biology Cyberinfrastructure Marine Biology

Infrastructure Innovation for Biological Research (347680)

National Science Foundation (NSF)
Federal Government
United States
US $300,000 - US $800,000
The Infrastructure Innovation for Biological Research Program by NSF aims to enhance contemporary biology through innovative research tools and methods. It focuses on developing or redesigning infrastructure in bioinformatics, instrumentation, and research methods. Projects should significantly advance biological understanding and be applicable to a wider research community. Proposals should aim at transforming biological research by either creating novel tools or adapting existing ones in meaningful ways, addressing fundamental questions in the biological sciences.
Biology Non-Medical Bioinformatics

FY 2023 Disaster Supplemental

US Department of Commerce: Economic Development Administration (EDA)
Federal Government
United States
Up to US $30,000,000
The FY 2023 Disaster Supplemental grant aims to support communities affected by major disasters, such as Hurricanes Ian and Fiona, by funding both construction and non-construction projects. This initiative focuses on long-term economic recovery strategies to address the challenges faced in areas with federal disaster declarations. Additionally, the Economic Development Administration has launched the Economic Development Grants Experience (EDGE) platform to enhance the efficiency and transparency of the grant management process.
Economic Services & Development Community Development & Revitalization Disaster Relief / Humanitarian Aid +1 more

ABC-CLIO Leadership Grant

American Library Association (ALA)
Association/Society
United States
Up to US $1,750
The ABC-CLIO Leadership Grant supports AASL Chapters in developing leadership programs for school library associations at various levels. This grant encourages initiatives that engage new members, train current leaders, and foster collaboration among organizations. Successful applications clearly define program objectives, participant groups, and include well-structured budgets and evaluation plans. The grant aims to promote innovative leadership approaches that can be replicated by other chapters, enhancing the overall effectiveness of school libraries.
Library Services

Toor Scholarship for Strong Public-School Libraries

American Library Association (ALA)
Association/Society
United States
US $1,000
The Toor Scholarship for Strong Public-School Libraries, established by the Toor Family, honors the legacy of Jay and Ruth Toor, who advocated for state-certified librarians in every school. This scholarship supports U.S. public school librarians who create local marketing campaigns to promote their libraries as vital community resources. Each recipient receives a $1,000 stipend to attend the AASL National Conference and must present their project, contributing to the advancement of school librarianship.
Library Services

Community Action Fund

Ndn Collective Inc
Private
Alaska, Canada +3 more
Up to US $15,000

Community Action Fund

A grant for Indigenous frontline organizations, groups, and individuals for direct action initiatives.

The Community Action Fund (CAF) grants support non-violent direct actions and organizing efforts that are often urgent and time sensitive. CAF prioritizes frontline, grassroots and community-based efforts that defend Indigenous peoples rights, communities and Nations.

Community Action Fund Intent

This grant supports Indigenous frontline, grassroots, community-based groups and organizations, Tribes, communities and villages, and individuals leading non-violent direct action or movement-building work in their effort to DEFEND Indigenous People’s rights, and protect their land, air, water, and natural resources.

Indigenous Services Environmental Conservation Freshwater Conservation +3 more

AHRQ Health Services Research Dissertation Program (R36) (347918)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $15,000
The AHRQ Health Services Research Dissertation Program (R36) provides crucial funding for doctoral candidates engaged in health services research. This program aims to support individuals in their academic pursuits, enabling them to contribute meaningfully to the field of healthcare. By fostering innovative research, AHRQ enhances the quality of health services and promotes evidence-based practices. Applications are due by 5:00 PM local time, ensuring timely submissions for those seeking to advance their academic careers.
Health & Medicine

Believe in Reading Grant

The Steve and Loree Potash Family Foundation
Association/Society
United States
Up to US $10,000
The Believe in Reading Grant, offered by The Steve and Loree Potash Family Foundation, targets established literacy programs with a proven track record. The foundation aims to support initiatives that address literacy across various age groups, particularly in areas of high need. Grants can be up to $10,000, with a focus on projects that earmark funds specifically for literacy. Applications are reviewed bi-monthly, and first-time applicants are limited to $3,000.
Literacy English for Speakers of Other Languages (ESOL) Education Vision Impairment Care & Services

CDV5 Foundation Grant

Cdv5 Foundation
Private
United States
Unspecified amount
The CDV5 Foundation Grant supports charitable organizations, churches, and government entities that meet IRS 501(c)(3) requirements. This grant aims to nurture successful children, foster stronger families, and cultivate healthier communities. Through partnerships, the foundation provides resources to help individuals reach their full potential. Applicants may submit one request annually for operating, capital, or program support, while event sponsorships are also considered. The foundation encourages applicants to consider their budget and history with the foundation when requesting funding.
Early Childhood Development Youth Development & Leadership Education - Preschool / Early Learning +6 more

Missouri Housing Trust Fund

Missouri Housing Development Commission
State/Local Government
Missouri
Up to US $300,000
The Missouri Housing Trust Fund, established in 1994, aims to address the housing needs of very low-income families and individuals in Missouri. Managed by the Missouri Housing Development Commission, it allocates funds for homeless prevention, rental assistance, and home repairs. The fund prioritizes individuals earning at or below 25% of the area median income, ensuring that resources effectively target the most vulnerable populations. Grants are capped at $150,000 per type and $300,000 per application.
Real Estate & Housing Equitable & Affordable Housing Supportive Housing & Shelters +1 more

TFish Fund Grant

TFish Fund
Private
Eastern Asia, United States
Up to US $10,000
The TFish Fund Grant aims to alleviate poverty in East Asia by empowering small but impactful NGOs to achieve sustainability and transparency. Founded in 2011, the Transparent Fish Fund partners with select organizations that focus on poverty alleviation. By providing financial aid, capacity building, and promoting accountability, the fund bridges the gap between Western donors and local NGOs, fostering a philanthropic spirit while addressing the complex social issues faced in the region.
Asian American Services

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) (348960)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.
HIV / AIDS

Research Experiences for Undergraduates (348985)

National Science Foundation (NSF)
Federal Government
United States
US $5,000 - US $500,000
The Research Experiences for Undergraduates (REU) program, funded by the National Science Foundation (NSF), promotes active research participation among undergraduate students across various research areas. It supports two mechanisms: REU Sites, which engage multiple students in ongoing research, and REU Supplements, which enhance existing NSF-funded projects. Participants must be U.S. citizens, nationals, or permanent residents, and each REU opportunity has its unique application process.
Geoinformatics & Geospatial Sciences Biology Physics +14 more

Rails-to-Trails Conservancy: Trail Grants

Rails To Trails Conservancy
Private
United States
US $10,000 - US $25,000

Rails-to-Trails Conservancy (RTC) Trail Grants

RTC’s Trail Grants are building strong foundations in communities for equitable trail network development and activation—investing in transformative projects and programs that create more access to trails for more people across the country.  

Our grants support organizations at all levels—from local and national nonprofits to public agencies—with a focus on community-based leadership, engagement and long-term impact.  

Since 2008, RTC has provided over $3.7 million in grant funding to more than 280 organizations seeking to create, connect and maintain the nation’s trails, building vibrant trail networks that connect neighborhoods and regions, and make it possible for America to walk, bike and be active outside.

Trail Creation & Maintenance Pedestrian & Bike-Friendly Infrastructure

Facility and Instrumentation Request Process (349109)

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Facility and Instrumentation Request Process (FIRP) enables the research community to propose projects requiring access to specialized instrumentation and facilities funded by the Facilities for Atmospheric Research and Education (FARE) Program. This solicitation offers three submission tracks: Education and Outreach, Single Facility Request, and Field Campaigns. Proposals are accepted anytime, with preference given to those submitted to programs within the Division of Atmospheric and Geospace Sciences (AGS) of the National Science Foundation.
Atmospheric Sciences Geoinformatics & Geospatial Sciences

Trail Accelerator Grants- Spring Cycle Planning and Design

International Mountain Bicycling Association
Private
United States
US $10,000 - US $30,000
The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.
Trail Creation & Maintenance Biking Pedestrian & Bike-Friendly Infrastructure

Mathematical Sciences Postdoctoral Research Fellowships

National Science Foundation (NSF)
Federal Government
United States
Up to US $190,000
The Mathematical Sciences Postdoctoral Research Fellowships (MSPRF) aim to support emerging leaders in mathematics and statistics. These fellowships enhance participants' research environments, ensuring significant scientific development. Awardees can choose between a Research Fellowship or a Research Instructorship, with funding available for research across various mathematical and statistical disciplines. Proposals are submitted directly to the NSF, and fellows must affiliate with eligible institutions or organizations.
Mathematics

St. Louis city Grants for Nonprofits Highlights

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Grant Insights : St. Louis city Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

94 St. Louis city grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

15 St. Louis city grants for nonprofits over $25K in average grant size

6 St. Louis city grants for nonprofits over $50K in average grant size

21 St. Louis city grants for nonprofits supporting general operating expenses

77 St. Louis city grants for nonprofits supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

4,000+ Grants on Instrumentl focused on Academic Scholarship Programs

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for St. Louis city grants for Nonprofits?

Most grants are due in the fourth quarter.

Q1
23.6%
Q2
26.2%
Q3
20.9%
Q4
29.3%

Typical Funding Amounts

What's the typical grant amount funded for St. Louis city Grants for Nonprofits?

Grants are most commonly $10,000.

$500 $500 Min.
$10,000 $10 K Median
$29,618 $29.6 K Average
$775,000 $775 K Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in St. Louis city Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the St. Louis city Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for St. Louis city Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

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