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Best St. Louis County Grants for Nonprofits in Missouri

Find the perfect St. Louis County grants for nonprofits on Instrumentl. 9,000+ St. Louis County grants for nonprofits in the United States.

9,000+

Available grants

$2.60B

Total funding

$5K

Median grant

9,000+ grants
$2.60B total
$5K median

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9,221 Results based on applied filters

NACRJ Mini-Grants

National Association of Community and Restorative Justice
Private
United States
Up to US $500
The NACRJ Mini-Grants provide funding of up to $500 for projects promoting community and restorative justice. Launched in 2016, the initiative has allocated over $60,000 to support NACRJ members nationwide. This unique opportunity fosters impactful projects and enhances visibility within the restorative justice community. Applications are accepted biannually, with a focus on empowering organizations and individuals committed to restorative practices. Members are encouraged to apply for this essential funding to further their meaningful endeavors.
Criminal Justice System Reform

NACRJ Impact Grant

National Association of Community and Restorative Justice
Private
United States
Up to US $3,000
The NACRJ Impact Grant, initiated in 2016, has provided over $60,000 to NACRJ members to support community and restorative justice projects. This grant is available annually, offering up to $3,000 to members for innovative initiatives that foster community impact. By applying, members can gain funding, visibility, and networking opportunities within the NACRJ and the broader restorative justice community, helping to empower meaningful projects that align with restorative justice principles.
Criminal Justice System Reform

Nationwide Fishing Trap, Removal, Assessment, and Prevention (TRAP) Program

Virginia Institute of Marine Science (VIMS)
State/Local Government
American Samoa, Guam +7 more
US $50,000 - US $200,000
The Nationwide Fishing Trap Removal, Assessment, and Prevention (TRAP) Program aims to eliminate derelict fishing traps nationwide. Focused on collaboration, it emphasizes standardized data collection, quantifying impacts, and comprehensive data sharing. With an annual budget of up to $1,475,000, the program supports 6 to 15 projects, providing grants ranging from $50,000 to $200,000 for 18-month initiatives. This effort significantly enhances marine resource conservation by reducing bycatch mortality and removing abandoned traps.
Carcinology (Crustaceans) Habitat & Ecosystem Restoration Marine / Ocean Conservation +2 more

Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) (358937)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,000,000
This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.
Pharmacology Addiction & Substance Use Disorders Drug Use Disorder

John Edelman Scholarship

Student Veterans of America
Private
United States
US $10,000
The John Edelman Scholarship supports student veterans pursuing careers in mental health counseling, offering five scholarships of $10,000 each. This initiative, funded by Student Veterans of America, emphasizes the importance of mental health support for veterans. Eligible candidates must be enrolled as full-time students in the 2025-2026 academic year and maintain strong academic performance. The scholarship aims to reward exceptional achievement and encourage further study in disciplines that promote mental well-being.
Military & Veterans Services Mental Health & Psychiatric Diseases Psychology

Madelyn L. Laschober Endowment Fund

Partners of the Americas Inc
Private
United States
Up to US $1,000
The Madelyn L. Laschober Endowment Fund, established by the Partners of the Americas Foundation, supports projects focused on youth, education, and microenterprise development. Offering an annual grant of up to $1,000, this initiative honors Mrs. Laschober's legacy and her contributions to Latin America. Through this fund, Partners of the Americas aims to empower communities and foster meaningful connections across the Western Hemisphere, reinforcing the importance of education and entrepreneurship.
Education Youth Services Microfinance

REI Cooperative Action Fund Grant

Rei Cooperative Action Fund
Private
United States
Unspecified amount
The REI Cooperative Action Fund Grant supports U.S.-based organizations that align with its mission to serve communities, particularly those connecting historically excluded individuals to the outdoors. The fund prioritizes initiatives that promote equitable access to outdoor spaces, enhance community health through nature, and create inclusive outdoor experiences. Eligible applicants must have a 501(c)(3) status and demonstrate a commitment to these values. However, individuals and certain organizations are not eligible for funding.
Outdoor Equity Outdoor Recreation Healthy Habits & Behaviors +1 more

Gainbridge Assists Powered by Parity Grant

Gainbridge
Corporate
United States
US $5,000
The Gainbridge Assists Powered by Parity Grant, in partnership with Parity and the Women’s Sports Foundation, supports girls and women in sports and education. In 2024, $222,000 will be awarded through 32 grants, including a $50,000 grant honoring Billie Jean King. This initiative aims to empower over 5,000 participants, fostering community transformation through sports and educational opportunities.
Women & Girl Services Sports & Athletics

Chrysalis Fund

Entomological Society of America (ESA)
Association/Society
United States
Up to US $2,500
The Chrysalis Fund, managed by the Entomological Society of America, supports K-12 educators in fostering youth interest in insect science. Grants can cover various project expenses, including supplies and travel costs. Funding levels include micro-grants (under $500), regular grants ($500-$999), and large grants ($1,000-$2,500). This initiative encourages innovative educational programs that engage students with entomology, enhancing their learning experience and promoting science education.
Entomology Education - K through 12

Sprouting School Gardens Grant

The Sprouts Healthy Communities Foundation
Corporate
Alabama, Arizona +22 more
Up to US $5,000
The Sprouting School Gardens Grant, provided by the Sprouts Healthy Communities Foundation, supports school-based gardening and cooking programs to foster healthy eating habits in children. Grants between $5,000 and $10,000 help cover program operations, supplies, and educator stipends. Eligible applicants include schools and 501(c)(3) nonprofits located in areas served by Sprouts Farmers Market, promoting meaningful connections between local teams and school gardening initiatives.
Horticulture & Gardening School Health

Growing Healthy Kids Grant

The Sprouts Healthy Communities Foundation
Corporate
Alabama, Arizona +22 more
US $5,000 - US $10,000
The Growing Healthy Kids Grant, funded by The Sprouts Healthy Communities Foundation, aims to support community-based programs that enhance children's nutrition access and health education. With grant amounts ranging from $5,000 to $10,000, this initiative focuses on hands-on programs that promote healthy habits among children and their families. Eligible organizations must be 501(c)(3) nonprofits located in areas where Sprouts Farmers Market operates, helping to ensure that the funds directly benefit local communities.
Children’s Health & Pediatrics Family Services Children’s Mental Health +3 more

Wellness Across the Lifespan Grant

The Sprouts Healthy Communities Foundation
Corporate
Alabama, Arizona +22 more
Up to US $5,000
The Wellness Across the Lifespan Grant supports the health of communities by providing access to nutritious food and essential nutrition education. Grants ranging from $5,000 to $10,000 are awarded to 501(c)(3) nonprofits in areas where Sprouts Farmers Market operates. This funding emphasizes health and nutrition education, as well as programs that promote healthy lifestyles and nutrition security, ultimately benefiting adults and vulnerable populations.
Nutrition & Healthy Eating Wellness & Healthy Living Health Disparities & Social Determinants of Health

White-Reinhardt Grant

American Farm Bureau Federation
Association/Society
United States
Up to US $1,000
The White-Reinhardt Grant offers funding for projects that enhance agricultural literacy among K-12 students. With grants of up to $1,000 available, state and county Farm Bureaus can initiate new educational programs or expand existing ones. This initiative, supported by the American Farm Bureau Federation and its Women’s Leadership Committee, honors the contributions of Berta White and Linda Reinhardt, aiming to bolster agricultural knowledge across the nation.
Education - K through 12 Agricultural Education

St. Mary's Bank Charitable Foundation- Donation and Sponsorship

St. Marys Bank Charitable Foundation
Private
United States
US $250 - US $2,500
St. Mary's Bank Charitable Foundation Community Support Grants aim to enhance community welfare by providing financial support to nonprofit organizations. With a commitment to 'people helping people' since 1908, the foundation focuses on areas like youth programming, homelessness, and civic support. In 2023 alone, they donated over $200,000 to 190 organizations, reflecting their dedication to improving lives in New Hampshire. They prioritize funding for nonprofits within their service areas, ensuring impactful contributions to local communities.
Basic Human Needs Military & Veterans Services Homelessness Services +7 more

Arkansas Audubon Society Trust Grants

Arkansas Audubon Society Inc.
Private
United States
US $500 - US $1,200
The Arkansas Audubon Society Trust Grants support conservation, research, and education projects focused on Arkansas bird species and their habitats. Established in 1972, the trust offers grants ranging from $100 to $1200, prioritizing projects within the state but considering broader initiatives as well. Eligible applicants include individuals, students, educators, and nonprofits. Proposals are accepted biannually, with meetings held to discuss funding decisions, fostering a community dedicated to avian conservation.
Ornithology Ornithological Conservation Environmental Conservation +2 more

Abbvie Parkinson’s Disease Grant

Abbvie Foundation
Corporate
United States
US $300,000
The Abbvie Parkinson’s Disease Grant aims to enhance the understanding and management of subcutaneous infusion therapies for advanced Parkinson’s disease. As these therapies become more prevalent, it is crucial for Movement Disorder Specialists and General Neurologists to develop confidence in identifying, mitigating, and managing infusion site events. This grant seeks to provide essential education and resources to support safe and effective treatment options for patients experiencing motor fluctuations.
Medical Education & Professional Training Parkinson’s Disease

BioMarin Grant

BioMarin
Corporate
North America
Unspecified amount
The BioMarin Grant aims to support events, activities, and projects that enhance public health and benefit patients with rare diseases. This corporate funder focuses on scientific innovation and provides resources for organizations such as hospitals, universities, and patient advocacy groups. With an emphasis on education and community support, BioMarin encourages applications for funding throughout the year, ensuring timely assistance for eligible projects.
Rare Diseases Hematological Systems Genetic Conditions & Birth Defects

BioMarin Medical Education Grant

BioMarin
Corporate
North America
Unspecified amount
The BioMarin Medical Education Grant offers funding for educational activities aimed at enhancing the knowledge and skills of healthcare professionals. Eligible applicants include accredited providers, medical associations, and patient advocacy groups. The grant focuses on supporting initiatives related to rare diseases, ensuring timely access to treatments and education. Applications are accepted year-round, but a minimum of 60 days is required for review prior to events. This commitment underscores BioMarin's dedication to improving patient care and advancing medical knowledge.
Rare Diseases Hematological Systems Genetic Conditions & Birth Defects +1 more

BioMarin Donation

BioMarin
Corporate
North America
Unspecified amount
BioMarin offers funding through its donation program focused on improving healthcare and patient advocacy, particularly for rare diseases. Organizations eligible for support include hospitals, accredited providers, and patient advocacy groups. BioMarin prioritizes innovative therapeutic solutions for rare genetic conditions. The company is dedicated to enhancing patient care and education, and it reviews funding requests year-round, although specific deadlines apply for year-end funding. This initiative reflects BioMarin's commitment to addressing unmet medical needs.
Children’s Health & Pediatrics Youth Services Disaster Relief / Humanitarian Aid +5 more

Strategic Projects: Capital Grants

M J Murdock Charitable Trust
Private
United States
More than US $100,000
The Strategic Projects: Capital Grants by the M J Murdock Charitable Trust offer vital funding opportunities for nonprofit organizations in the Pacific Northwest. These grants support transformative projects that enhance community well-being through construction, renovation, and infrastructure investments. Eligible entities include 501(c)(3) nonprofits and government entities. The Trust emphasizes projects that demonstrate strong community impact and funding diversification, ensuring sustainable growth and lasting benefits for the communities served.
Nonprofit Growth & Development Art & Culture Education +6 more

Strategic Projects: Equipment & Technology Grants

M J Murdock Charitable Trust
Private
United States
More than US $50,000
The M J Murdock Charitable Trust offers Strategic Projects: Equipment & Technology Grants to nonprofits in the Pacific Northwest. These grants focus on capacity-building projects and essential equipment, requiring recipients to cover at least 50% of costs. Eligible organizations include 501(c)(3) nonprofits and tribal entities. Priority is given to projects enhancing community services, education, and environmental stewardship, supporting initiatives that foster human flourishing and demonstrate diversified funding.
Art & Culture Education Community Services +6 more

Bridging Investments in Abortion and Contraception Research Grant

Society Of Family Planning
Private
United States
Up to US $100,000
The Society of Family Planning is offering the Bridging Investments in Abortion and Contraception Research Grant to support the completion of NIH grants focused on abortion and contraception. This funding aims to mitigate the impact of recent funding terminations by ensuring that vital research continues, promoting equitable access to reproductive health. Proposals can request up to $100,000 and must detail their alignment with the Society's mission, planned activities, and budget within a 24-month timeline.
Reproductive Health Women's Health Reproductive Rights

The Slomo and Cindy Silvian Foundation Grant

Slomo And Cindy Silvian Foundation Inc
Private
United States
Unspecified amount
The Slomo and Cindy Silvian Foundation Grant supports a range of subjects including education, children's welfare, medical care, medical research, and Jewish philanthropic endeavors. Established in honor of Cindy Silvian, the foundation has awarded over $30 million since 2008. Applications are by invitation only, and organizations must meet specific eligibility criteria to be considered for funding. This year, the foundation allocated over $2.4 million to more than 110 organizations, highlighting its commitment to impactful philanthropy.
Education Health & Medicine Child Welfare Services +5 more

Avant Garde Award for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $700,000
The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.
HIV / AIDS Addiction & Substance Use Disorders

NIH Science Education Partnership Award (SEPA)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Science Education Partnership Award (SEPA) fosters innovative educational initiatives aimed at pre-college students, promoting their interest in STEM fields, especially in biomedical and behavioral sciences. This program supports both classroom projects and informal science education activities, such as after-school programs and library events. Emphasizing the development of quantitative and computational skills, SEPA seeks to inspire the next generation of scientists and thinkers through engaging educational experiences.
STEM / STEAM Education Education - K through 12 Biology

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
This funding opportunity aims to support innovative research projects targeting previously undruggable classes of proteins associated with challenging human diseases. By encouraging early-stage exploratory projects, it seeks to foster the development of novel methods and agents that can selectively modulate these hard-to-target proteins, ultimately advancing therapeutic strategies and improving patient outcomes.
Pharmacology Rare Diseases

Greenpoint Foundation Grant

Greenpoint Foundation Inc.
Private
United States
Unspecified amount
The Greenpoint Foundation Grant aims to enhance community life by supporting organizations that focus on agriculture, food security, education, and community enhancement. Established in 2022, the Foundation accepts grant applications year-round for both general operating budgets and specific projects. Priority is given to 501(c)(3) organizations and local government entities, while faith-based programs are considered on a case-by-case basis. Grant recipients must submit impact reports to ensure continued support.
Education Agriculture Food Security +2 more

St. Louis County Grants for Nonprofits Highlights

Looking for St. Louis County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all St. Louis County grants recommended for your specific programs in Missouri.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : St. Louis County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ St. Louis County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

16 St. Louis County grants for nonprofits over $25K in average grant size

6 St. Louis County grants for nonprofits over $50K in average grant size

19 St. Louis County grants for nonprofits supporting general operating expenses

88 St. Louis County grants for nonprofits supporting programs / projects

4,000+ Grants on Instrumentl focused on Academic Scholarship Programs

400+ Grants on Instrumentl focused on Early Childhood Development

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for St. Louis County grants for Nonprofits?

Most grants are due in the first quarter.

Q1
27.7%
Q2
22.3%
Q3
23.2%
Q4
26.8%

Typical Funding Amounts

What's the typical grant amount funded for St. Louis County Grants for Nonprofits?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$27,026 $27 K Average
$775,000 $775 K Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in St. Louis County Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the St. Louis County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for St. Louis County Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

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