Best Unrestricted Grants for Nonprofits in Texas

The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.

The Waide-Betty Medical Scholarship Fund, managed by the Amarillo Area Foundation, supports college students from Ochiltree, Hansford, Lipscomb, Hutchinson, Roberts, or Hemphill counties pursuing careers in medical, nursing, pharmacy, dental fields, or as physician assistants. This fund ensures that deserving students can access higher education while maintaining full-time enrollment and adhering to GPA requirements. Established in 1957, the Amarillo Area Foundation plays a vital role in addressing healthcare needs in the Texas Panhandle.

The NCAA Jim McKay Graduate Scholarship honors the legacy of journalist Jim McKay by awarding a one-time $10,000 scholarship to one male and one female student-athlete annually. Eligible candidates must have a minimum GPA of 3.5, demonstrate integrity, and show interest in sports communication. There is no limit to the number of nominations from institutions, highlighting the NCAA's commitment to supporting student-athletes in their academic and professional pursuits.

Opera Grants for Women Composers: Discovery Grants support the creation of new operas by women composers, promoting gender parity and diversity in the field. These grants assist composers in exploring opera as an art form, funding activities like libretto readings and workshops. OPERA America is committed to enhancing the operatic repertoire with diverse perspectives, and these grants are made possible through the support of the Virginia B. Toulmin Foundation.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.

The Henry Luce Foundation's Asia: Responsive Grants program supports initiatives that enhance understanding of East and Southeast Asia. With a focus on academic research, cultural exchange, and public education, the program seeks to promote collaboration between American and Asian institutions. Grants are awarded primarily to U.S.-based non-profits, fostering innovative teaching, resource development, and policy engagement, while prioritizing projects that bridge diverse disciplines and geographic divides.

The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.

The CLRA Research Grant Program, led by the Children’s Leukemia Research Association, focuses on funding innovative research aimed at uncovering the causes of leukemia and improving treatment options. Grants totaling $30,000 are awarded to U.S.-based researchers, with the intention of advancing scientific understanding and ultimately finding a cure. The program has made significant contributions to the high cure rates for childhood leukemia, showcasing the importance of continued research in this field.

The Parkinson's Foundation offers Community Grants to support impactful programs for people with Parkinson's disease across the U.S. With over $5 million awarded in the last three years, the Foundation aims to enhance health, wellness, and education. Eligible applicants include local non-profits and healthcare facilities focusing on mental health, care partner support, and exercise programs tailored for PD. This initiative promotes diversity, equity, and inclusion in service delivery.

The Williams – Dr. Dana Williams Scholarship, offered by the Coastal Bend Community Foundation, supports graduating seniors from CCISD high schools pursuing education majors. This scholarship aims to enhance educational opportunities for future teachers, contributing to the community's growth and quality of life. With a legacy of impactful philanthropy, the Foundation continues to address social and educational needs through its various funds. Students in the Coastal Bend area are encouraged to apply for this valuable opportunity.

The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.

The Austin Education Foundation Scholarship, established by a committee from the Austin School District, aims to support local high school seniors in their pursuit of post-secondary education. With an estimated total award of $3,500 over four years, the scholarship is designed to honor the legacy of Austin High School Alumni. To be eligible, applicants must belong to the Austin School District and submit an activity resume, facilitating a pathway for deserving students to achieve their educational dreams.

The Cooley, Dearing And Rinker Foundation Scholarship, managed by the Northern Piedmont Community Foundation, supports graduates from public schools in Winchester, Frederick, Rappahannock, and Warren Counties. Applicants must demonstrate financial need and show commitment to their college education. Award amounts typically range from $1,000 to $5,000, helping students pursue their academic goals. The foundation has a strong history of addressing community needs since its establishment in 2000.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Michael Petronchek Musical Scholarship Fund

Mike Petronchek was a well known musician in our community. During the 40′s Mike played trombone in Angie Sgro and Johnny Murphy’s Dance Band. He loved the Big Band sound and attended many of the formal dances that were held at Laube Hall in Freeport to benefit charity. Mike served as a radio operator with the 8th Air Force during World War II because of his great “ear”. He received his bachelor’s degree from IUP and his master’s from Penn State.

For nearly four decades Mike shared his love of music with children here in Armstrong County. He was the Ford City High School music director from 1958 through 1984 and organized the county’s first elementary school band at Lenape Elementary. In his honor, the Michael Petronchek Musical Scholarship Fund was established for Ford City High School graduates pursuing an education in music.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Joan Tatsak Memorial Scholarship

Joan Tatsak was a beloved friend, colleague and mentor to many of our friends and neighbors here in Armstrong County. She inspired and encouraged her peers and coworkers to achieve and strive for excellence. This unique fund is a fitting memorial. The Joan Tatsak Memorial Fund is a non-traditional scholarship fund that offers grants for entrepreneurship, leadership and scholarship.

Scholarship Details

• Available to Adult Students
• Nonrenewable

All ACCF Scholarships are merit based.

$20K for changemakers with transformative ideas & firsthand insight in early childhood

About the Imagine Award

The Imagine Award by the Promise Fund offers $20,000 in flexible funding (see definition in FAQs) and a six-month cohort-based learning experience for community-rooted early childhood leaders with ideas for transformative impact. ​​Award recipients are at the idea stage and will launch a pilot within six months, testing their solutions with real users, gathering feedback, and refining their approach.

Imagine Award recipients will learn strategies for designing and executing lightweight tests for rapid learning while gaining clarity on their idea's direction using impact and business models. They will craft a compelling story about their work to build future partnerships and run a focused pilot with strong feedback loops for gathering data, all while growing alongside a supportive peer community.

What We Provide

Our grant dollars are flexible and meant to be used at award recipients’ discretion for the pursuit of tests or a pilot of a transformative idea. Read the FAQ for more information.

Direct, one-on-one support from our team to help you learn, get tailored help, and make relevant connections.

Multi-day gathering for peer connection, learning, and pilot design.

Access to a bench of mentors to guide you as you transition out of the program and navigate next steps with your pilot.

Light, tailored coaching to support pilot preparation, launch, and implementation.

Ongoing peer community and resources to continue learning and collaboration

Charlottesville Promise Scholarship

The Charlottesville Promise Scholarship is a multi-year award that can fund up to $13,000 of the cost of a two or four year undergraduate degree, or a vocational training/professional certificate program at an accredited technical school. Charlottesville Scholarship Program typically awards nine new scholarships each year to seniors attending Charlottesville High School, one potential new scholarship each year to a graduating high school senior residing in Charlottesville City and attending an alternative or non-traditional learning centers listed here, and one potential new scholarship each year to an eligible adult student currently attending or planning to enroll in a post-secondary undergraduate program or vocational training/professional certification program at an accredited technical school.   

Health Services Research in Alzheimer’s Disease and Related Disorders (HSR-ADRD) Program

The HSR-ADRD program seeks to support research that strengthens dementia detection, diagnosis, and post-diagnostic care pathways along the care continuum. Projects may address a range of health services research questions, including, but not limited to, studies examining barriers and solutions to timely access, quality, and care coordination. By supporting rigorous and innovative research, this program aims to generate actionable evidence to improve person-centered, coordinated, and equitable brain health and dementia care.

Program overview

The program welcomes proposals that utilize rigorous methodologies to advance understanding and improvement of cognitive impairment, including MCI and Alzheimer’s disease and related dementias (AD/ADRD) detection, diagnosis, and post-diagnostic care.

This award is structured as an individual research grant, with funding administered through the recipient’s institution. Proposals should address one or more Areas of Focus. Areas of Focus represent high-priority research topics for which this program is actively seeking proposals and include: 

• The Value of Early Detection and Diagnosis: Studies should investigate outcomes associated with early detection and diagnosis on at least two levels of the dementia care ecosystem (i.e., individual/families, providers/clinicians, health systems/payers, and policy/society).
• Care Pathways for Individuals with MCI or Dementia: Studies should consider comorbidities and investigate how people are being screened and diagnosed in different settings, and the post-diagnosis pathways for care and treatment, including pharmacological and non-pharmacological interventions or combinations thereof.

Funding overview

• Each HSR-ADRD award is limited to a total of $250,000 U.S. (direct and indirect costs) for a duration of up to two years (awards should be a minimum one year).
• Indirect costs are capped at 10 percent of total direct costs and are inclusive of indirect costs for the implementing institution as well as for any subcontracts.

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Liesel M. Hiemenz Scholarship

This permanent scholarship was established in memory of Ms. Hiemenz, a nurse from Germany. Preference is given to applicants interested in public health.

The Autism Centers of Excellence R01 aims to advance research in autism through collaborative networks, enhancing the past 23 years of progress. This initiative encourages innovative methods and technologies, inviting experts to consider applying for future funding opportunities. Although applications are not currently solicited, potential applicants are urged to form meaningful collaborations. This funding opportunity reflects a commitment to improving research in autism, leveraging diverse scientific expertise to address critical challenges in the field.

The Autism Centers of Excellence (ACE) initiative, spearheaded by the Eunice Kennedy Shriver National Institute for Child Health and Human Development along with several other prominent institutes, aims to encourage innovative research projects. While applications are not currently open, potential applicants are urged to prepare collaborative proposals that leverage cutting-edge technologies. This funding opportunity, utilizing the P50 Research Program Projects and Centers activity code, seeks to build upon over two decades of research advancements.

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Lucy C. Perry Scholarship

Preference for funds from this scholarship is given to applicants studying at Indiana University and interested in public health.

The American Heart Association (AHA) is launching the RFP for a Strategically Focused Research Network (SFRN) aimed at enhancing the early detection and delaying the progression of valvular heart disease. This initiative seeks collaborative proposals from researchers to address critical questions and advance understanding in this field. With a maximum budget of $4.4 million and a duration of four years, the AHA plans to award at least three grants based on scientific merit and alignment with its mission.

The Bowman Family Swimming Scholarship, provided by the Central Kentucky Community Foundation, aims to support graduating high school seniors in Hardin County who are active swimmers. Eligible applicants must have a minimum cumulative GPA of 3.0 and be involved with their school's swim team. This scholarship embodies the Foundation's mission to enhance community life by empowering students to pursue their educational goals in athletics.

The Towsley Foundation Grants support initiatives that enhance community welfare and sustainability, focusing on diverse fields such as education, health, and the arts within Michigan. With a commitment to effective philanthropy, the foundation prioritizes projects that demonstrate creativity and strategic impact. Eligible organizations must operate in Michigan and adhere to specific funding guidelines, fostering financial sustainability. Grants are allocated based on project merit and organizational capacity, reinforcing the foundation's mission to improve lives through thoughtful partnerships.

The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.