Best Unrestricted Grants for Nonprofits in Texas

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.

$20K for changemakers with transformative ideas & firsthand insight in early childhood

About the Imagine Award

The Imagine Award by the Promise Fund offers $20,000 in flexible funding (see definition in FAQs) and a six-month cohort-based learning experience for community-rooted early childhood leaders with ideas for transformative impact. ​​Award recipients are at the idea stage and will launch a pilot within six months, testing their solutions with real users, gathering feedback, and refining their approach.

Imagine Award recipients will learn strategies for designing and executing lightweight tests for rapid learning while gaining clarity on their idea's direction using impact and business models. They will craft a compelling story about their work to build future partnerships and run a focused pilot with strong feedback loops for gathering data, all while growing alongside a supportive peer community.

What We Provide

Our grant dollars are flexible and meant to be used at award recipients’ discretion for the pursuit of tests or a pilot of a transformative idea. Read the FAQ for more information.

Direct, one-on-one support from our team to help you learn, get tailored help, and make relevant connections.

Multi-day gathering for peer connection, learning, and pilot design.

Access to a bench of mentors to guide you as you transition out of the program and navigate next steps with your pilot.

Light, tailored coaching to support pilot preparation, launch, and implementation.

Ongoing peer community and resources to continue learning and collaboration

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Joan Tatsak Memorial Scholarship

Joan Tatsak was a beloved friend, colleague and mentor to many of our friends and neighbors here in Armstrong County. She inspired and encouraged her peers and coworkers to achieve and strive for excellence. This unique fund is a fitting memorial. The Joan Tatsak Memorial Fund is a non-traditional scholarship fund that offers grants for entrepreneurship, leadership and scholarship.

Scholarship Details

• Available to Adult Students
• Nonrenewable

All ACCF Scholarships are merit based.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Michael Petronchek Musical Scholarship Fund

Mike Petronchek was a well known musician in our community. During the 40′s Mike played trombone in Angie Sgro and Johnny Murphy’s Dance Band. He loved the Big Band sound and attended many of the formal dances that were held at Laube Hall in Freeport to benefit charity. Mike served as a radio operator with the 8th Air Force during World War II because of his great “ear”. He received his bachelor’s degree from IUP and his master’s from Penn State.

For nearly four decades Mike shared his love of music with children here in Armstrong County. He was the Ford City High School music director from 1958 through 1984 and organized the county’s first elementary school band at Lenape Elementary. In his honor, the Michael Petronchek Musical Scholarship Fund was established for Ford City High School graduates pursuing an education in music.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.

The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.

About Us

We are YOUR Community Foundation! Our mission is to bring people and resources together to strengthen the quality of life, both now and in the future, for the residents of Randolph County.

The Community Foundation of Randolph County, Inc. is here to make our community the very best place to live, work, and raise a family. As a non-political private organization, we are uniquely able to provide grant money for innovative projects that have a major impact on our community.

Ann & Wayne Hinchman Scholarship

Wayne and Anna (Ann) Hinchman were both born in Adams County in 1915. Wayne graduated from Geneva High School and Manchester College. He taught history, science, and physical education and coached. He helped found the Winchester High School track and football programs. He was principal of Willard Elementary School for 35 years. He was also a long- time referee for high school and college basketball games. Wayne served as Deacon and Elder for the First Presbyterian Church of Winchester. Anna Hinchman was a graduate of Berne High School. She was president of the Women’s Association of the First Presbyterian Church, taught Sunday School and was the director of Vacation Bible School. Ann was also a Brownie and Girl Scout Leader and loved working in her beautiful garden that she kept at her home for decades. 

The State Fair of Texas offers grants ranging from $5,000 to $10,000 to support nonprofit organizations in the South Dallas/Fair Park community. This initiative aims to foster economic development, capacity building, educational programming, and social justice. Organizations within a ten-mile radius of the Fair are encouraged to apply, and collaboration with local entities is essential for favorable consideration. Interested applicants should choose between applying for a grant or a sponsorship within the same year.

Emand Hamad, M.D. Healthcare Career Scholarship

Provides scholarships to students planning on majoring in a healthcare major.

About the Awards

The late Dr. James F. Fries, formerly professor emeritus of medicine at Stanford University, came up with the idea for the James and Sarah Fries Prize for Improving Health in a 1987 ascent of Nepal’s Makalu—one of the world’s highest peaks—when his party became trapped in a severe snowstorm and was ultimately unable to scale the mountain.

Following that experience, Dr. Fries returned to sea level and set about establishing a foundation to support a Nobel-like prize for health that now annually awards a $100,000 prize to an an outstanding leader judged by an expert panel to have done the greatest good for the greatest number of people in the field of health.

In 1992 the Elizabeth Fries Health Education Award was established in honor of Elizabeth Fries, daughter of James and Sarah Fries. The $50,000 prize is awarded annually to an individual judged to have made substantial contributions to their area of health education and health promotion. Sarah Fries remained active in the Fries Awards for Health program until her death in May 2017, and Jim Fries remained active in the awards until his death in November 2021.

The CDC Foundation is honored to partner with the James F. and Sarah T. Fries Foundation, which established and funds the award. As of 2016, the CDC Foundation manages and administers the Fries Awards for Health program, which include the James and Sarah Fries Prize for Improving Health and the Elizabeth Fries Health Education Award.

The Andrew Lloyd Webber Initiative offers Classroom Resources Grants aimed at enhancing theatre education in under-resourced public schools. Funded by a $1.3 million grant from the Andrew Lloyd Webber Foundation, the initiative provides essential resources, scholarships, and grants to foster artistic growth. By supporting diverse students and schools, this program opens pathways to careers in theatre, ensuring all young people have access to quality arts education, thereby enriching the cultural landscape of America.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

Anne K. Petry Scholarship Fund

Established by Summit Education Partnership Foundation to provide scholarships for Akron Public Schools students studying special education.

Amount:

• $1,000

Number of awards:

• 1

Renewal:

• No

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.

The Global Down Syndrome Foundation's Education Awards support innovative educational programs aimed at enhancing the lives of individuals with Down syndrome. This initiative encourages applications for workshops, conferences, and webinars focused on research and medical advancements. Eligible applicants must be members of the foundation or recognized 501(c)(3) organizations, ensuring impactful contributions that benefit the Down syndrome community. With no funding limits for consecutive years, this program promotes significant educational outreach and advocacy.

The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.

The Abortion Bridge Collaborative Funds, initiated by the Women Donors Network, aim to enhance abortion access across the U.S. in response to the 2022 Dobbs decision. The fund prioritizes support for 501c3 organizations committed to reproductive justice, focusing on immediate community needs and sustainable solutions. Emphasizing grassroots leadership and innovative approaches, the fund seeks to build a robust infrastructure for reproductive care, ensuring equitable access for all individuals in need.

The B-Fund Grant by the Brem Foundation aims to enhance early detection of breast cancer by funding crucial screening and diagnostic tests for women in need. This initiative supports entities in the DC metro area, providing financial assistance for services like mammograms and ultrasounds, while ensuring equitable access regardless of socio-economic status. However, it excludes costs related to post-diagnosis care, employee salaries, and administrative expenses, promoting targeted and effective use of funds in the fight against breast cancer.

The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.

The AMA Foundation Physicians of Tomorrow Scholarship: Alliance Grassroots provides $10,000 in tuition assistance to medical students entering their final year. With a commitment to supporting diversity in medicine, this scholarship focuses on candidates interested in women's and children's health issues. Open to all medical students, it recognizes volunteerism and research in health-related fields. Since 1950, the AMA Foundation has awarded over $61 million in scholarships, fostering a diverse cohort of future healthcare professionals.

The Young Investigator Grant from Alex's Lemonade Stand Foundation supports early career researchers in pediatric oncology. This grant, offering up to $50,000 per year for three years, aims to cultivate promising researchers and encourage innovative research ideas. With a commitment to changing the lives of children with cancer, ALSF plays a crucial role in funding impactful research and empowering the next generation of scientists dedicated to this vital cause.

The Jonathan Larson Grants provide essential support to emerging musical theatre artists, helping composers, lyricists, and librettists further their creative endeavors. Established in memory of Jonathan Larson, creator of the iconic musical "Rent," these grants empower artists to create impactful work that resonates with contemporary culture. The program, sustained by the American Theatre Wing and the Larson Family, encourages professional growth and artistic exploration without the limitations of specific projects.

The Early Career Research Programs: 'A' Award Grant by Alex's Lemonade Stand Foundation aims to support promising early career scientists in pediatric oncology. This grant fosters innovation in childhood cancer research by funding original projects that are not currently financed. Applicants must demonstrate a commitment to pediatric cancer investigation and provide a solid career development plan with mentorship. The funding can reach up to $800,000 over four years, with a maximum of $200,000 available annually.

The Society of Toxicology offers the Supplemental Training for Education Program (STEP), which provides up to $1,000 to support graduate students in toxicology seeking additional training to address skill gaps. Eligible applicants must be PhD students who have completed coursework and passed comprehensive exams. The funding covers workshops or courses not available through their graduate program, enhancing career prospects in toxicology.

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.