Best Unrestricted Grants for Nonprofits

The Life Comes From It Grant, funded by the Tides Foundation, supports grassroots initiatives focused on restorative, transformative, and indigenous justice. It prioritizes projects led by communities of color, emphasizing alternatives to incarceration and community-led solutions. Applicants must be 501c3 organizations based in the United States. This grant fosters a collaborative approach to healing and justice, aiming to shift power dynamics and promote inclusive practices across generations.

Overlake Corporate Sponsorship aims to support local organizations that enhance community well-being. With a focus on non-profits in the Eastside area, we prioritize partnerships addressing healthcare access, mental health, and homelessness. Our criteria emphasize valid 501(c)(3) status and alignment with our community health goals. While we value every sponsorship request, we must judiciously allocate resources to ensure maximum community impact.

The Longleaf Fund Grant supports capital projects aimed at enhancing the lives of at-risk children and youth across the Carolinas. Focusing on building accessible play spaces, promoting educational technology, and improving environments for children with disabilities, this grant encourages community engagement and collaboration. Eligible projects must be completed within 12-18 months and demonstrate significant community support. The fund prioritizes initiatives that address the needs of vulnerable populations and can secure additional funding.

The Water System Sustainability Grant Program provides essential funding for community water systems to enhance their operational efficiency through effective asset management practices. This initiative supports both new programs and improvements to existing asset management efforts, encouraging proactive management strategies that ensure sustainability and financial viability. With a focus on technical and managerial capacity, the program aims to empower communities to make informed decisions about their water infrastructure and resources.

The Water System Sustainability Grant Program provides funding to assist community water systems in developing sustainable operations and improving their technical, managerial, and financial capacities. The Strategic Planning Grant specifically supports the creation of engineering and hydrogeological reports, helping decision-makers implement necessary infrastructure improvements. Eligible projects include alternative analysis studies, pilot studies, and source exploration investigations. This initiative aims to secure necessary funding through informed outreach and detailed planning.

The Community Clinic Grant, funded by the Minnesota Department of Health, aims to enhance mental health services for all ages, improve oral health programs, and provide clinical services for at-risk youth up to 25 years old. This initiative emphasizes collaborative practice among dental hygienists in community settings to expand access to essential health services, thereby addressing critical healthcare needs in vulnerable populations. Funding is available for projects that meet these objectives.

The Individual Artist Fellowship Awards, offered by the New Jersey State Council on the Arts, support practicing artists in New Jersey to pursue their artistic goals. With two application deadlines on July 2 and July 16, 2025, these fellowships are awarded based on the artistic quality of submitted work, evaluated by independent panels. Eligible artistic categories range from Film and Digital to Painting and Interdisciplinary works, fostering creativity across diverse disciplines.

Cancer Prevention in Maine

Cancer remains a leading cause of death in Maine, impacting thousands of Mainers each year. Fortunately, there are many ways to reduce cancer risk and prevention certain types of cancer, ultimately reducing the burden of the disease in our state.

To support cancer prevention efforts, Maine Cancer Foundation is now accepting applications for evidence-based interventions to reduce the risk of cancer in Maine.

Cancer Prevention Focus Areas that will be considered include:

• Alcohol Use
• Environmental Factors that Impact Cancer (Arsenic, PFAs, Radon)
• HPV Vaccinations
• Obesity Prevention
• Sun Safety
• Tobacco Use and Prevention and/or Treatment

Proposals should utilize evidence-based practices in preventing cancer. Please be prepared to provide quantitative and/or qualitative data to support your proposed strategies throughout an application.

Grant Term & Request Amount

Applicants may request a 1- or 2-year grant. Request amounts up to $40,000 per year will be accepted. The maximum request over two years is $80,000. Please note, requests do not have to meet the maximum amount. Smaller, pilot projects are also encouraged.

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

Lawrence M. Brass, MD Clinical Research Training Scholarship in Stroke

This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies related to stroke, vascular neurology, and neurocritical care.

For the purpose of this scholarship, research is defined as “patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance diagnosis of neurological disease. These areas of research include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health services and outcomes research.” Disease-related studies not directly involving humans or human tissue are also encouraged if the primary goal is the development of therapies, diagnostic tests, or other tools to prevent or mitigate neurological diseases.

The Philadelphia Botanical Club Grant supports members engaged in research, education, and conservation projects focused on plant life in the Philadelphia area. This includes studies on flora, algae, lichens, and fungi, with an emphasis on advancing knowledge through peer-reviewed publications and community engagement. Eligible applicants must be current members of the Club, and projects can receive funding for supplies, educational materials, and travel expenses, with a preference for smaller grants.

Montana State University

Montana State University (MSU), the state’s largest public research university, serves as Montana’s premier land-grant institution dedicated to education, research, and service. Founded in 1893 in Bozeman, MSU provides high-quality, accessible learning opportunities while advancing discoveries that address the needs of Montana, the nation, and the world. With more than 16,000 students and a strong commitment to hands-on, experiential learning, MSU integrates academic excellence with real-world problem-solving across fields such as agriculture, engineering, health, science, and the arts.

Guided by its land-grant mission, MSU prioritizes student success, community engagement, and research that strengthens Montana’s economy and quality of life. The university strives to foster innovation, expand opportunity, and support thriving communities by preparing graduates who are equipped to lead, serve, and contribute meaningfully to society.

Hugh Hastings Memorial Scholarship

This scholarship supports Montana residents with sophomore status who are pursuing a degree from either the College of Agriculture or the College of Arts and Architecture, alternating by year. Applicants must maintain a minimum 2.7 cumulative GPA. Award amounts vary, and the scholarship falls under the Agriculture and Arts and Architecture scopes.

The Helen M. Heitmann Young Scholar Award, presented by SHAPE America, honors young professionals who have made significant contributions to research in curriculum and instruction within health and physical education. Eligible candidates must be current SHAPE America members and have 3 to 6 years of experience post-doctorate. This award emphasizes active involvement and scholarship in the field, encouraging innovative research that enhances educational practices for preK-12 students.

The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.

About NABT

Since its establishment in 1938, the National Association of Biology Teachers (NABT) has been the recognized "leader in life science education." Thousands of educators have joined NABT to share experiences and expertise with colleagues from around the globe; keep up with trends and developments in the field; and grow professionally.

NABT Mission

The National Association of Biology Teachers empowers educators to provide the best possible biology and life science education for all students.

Climate Education Action Award

Sponsored by NCSE, this award recognizes excellence in classroom/community education that specifically supports and promotes the accurate and robust teaching of climate science and the impact of the changing climate on society beyond the classroom. This award is presented to K-12 teachers in odd-numbered years and undergraduate and/or informal educators in even-numbered years. NCSE’s sponsorship of this award includes a $1,000 honorarium. The recipient also receives a recognition plaque to be presented at the NABT Professional Development Conference and one year of complimentary membership to NABT.

Virginia Department of Forestry

The Virginia Department of Forestry (DOF) was established in 1914 to prevent and suppress forest fires and reforest bare lands. More than 100 years later, we still fight wildfires and plant trees, but the agency has grown and evolved to meet the needs of Virginians and the forestry community.

DOF has a number of program areas, each focused on a specific aspect of forestry. The agency’s mission is to protect and develop healthy, sustainable forest resources for Virginians. The Virginia Department of Forestry (DOF) is led by the state forester as established in the Code of Virginia §10.1-1100. The state forester is appointed by the Governor of Virginia and serves under the direction of the Secretary of Agriculture and Forestry. The state forester is responsible for ensuring that the agency accomplishes its mission to protect and develop healthy, sustainable forest resources. 

Hemlock Woolly Adelgid Treatment Cost-Share Program

Treating hemlock trees for this destructive non-native insect increases the chance of preserving genetic material of hemlock trees throughout the state. The Hemlock Woolly Adelgid Treatment Cost-Share Program can help landowners and organizations offset project costs of the treatment of approved eastern or Carolina hemlock trees. Cost-share payment is a reimbursement up to 100% of direct project costs up to $500. If the sum of project costs is over $500, then cost-share payment will be $500 OR 50% of direct project costs, whichever is higher. Cost-share payment may not exceed $1,500 per organization or landowner. Treatment of hemlock trees must be one of the approved methods listed below and all trees must be assessed by a DOF forester prior to enrollment.

The SAF Technology Transfer Award honors exceptional contributions to technology transfer in forestry by an SAF member. It recognizes leaders who have significantly impacted forestry practices through innovation and quality work. The award includes a $1,000 honorarium, complimentary registration for the SAF convention, and up to $500 for travel costs. Presented at the SAF national convention, it emphasizes the importance of effective technology transfer for sustainable forest management.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.

The Marisla Foundation, established in 1986, offers a Human Services Grant aimed at supporting women in crisis in Orange County and Los Angeles, California. This grant focuses on enhancing physical, emotional, and financial wellbeing through stable housing, addiction treatment, and vocational training. Eligible organizations must possess 501(c)(3) tax-exempt status. The foundation does not support individual applications or multiple submissions from the same organization within a year, ensuring a fair and equitable distribution of resources.

The IRSS RIFM Special Award for Inhalation Toxicology offers a $500 prize for trainees contributing to inhalation toxicology research. Sponsored by the Society of Toxicology, this award encourages innovative evaluations of inhaled toxicants, exposure science advancements, and risk assessment research. Applicants must submit a one-page summary of their work and a pending abstract for presentation at the SOT Annual Meeting, alongside a mentor's support letter. This award aims to promote excellence in the field.

Berkshire Taconic Community Foundation

Since 1987, we have strengthened communities through philanthropy and leadership. We channel generosity where it is needed, bringing together resources and passion to tackle our region’s most pressing issues and create lasting change.

The Region We Serve

Berkshire Taconic Community Foundation serves Berkshire, Columbia, northeast Dutchess and northwest Litchfield counties. This unique area where New York, Connecticut and Massachusetts meet contains 2,200 square miles of natural beauty and small-town charm that is home to nearly 230,000 people.

Fund for Columbia County: General Operating Support Grants

Introduction

Berkshire Taconic Community Foundation established the Fund for Columbia County (FCC) in 1998 to help strengthen communities and improve the quality of life for everyone in Columbia County. The fund serves as a resource for organizations that make life safer, healthier, and more equitable for all residents of the county.

Grants for General Operating Support

Through its General Operating Support Grants, FCC supports organizations that have a deep, lasting, and positive impact on the residents of Columbia County, with particular emphasis on low-income and underserved adults and children.

FCC’s primary focus areas include:

• Youth development
• Education
• Services for the elderly
• Health and social services
• Civic and community engagement through arts, culture, and education

These Grants provide flexible general operating support, which may include:

• Personnel and overhead costs
• Planning and implementation of programs
• Technology, equipment, or material costs
• Strategic planning, staff/board development, and/or succession planning
• Investments to increase organizational capacity
• Other annual operating expenses

The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.

The Juliette P. Doster Scholarship Fund honors the legacy of Mrs. Doster, who dedicated forty years to improving healthcare in Calhoun County. This renewable scholarship supports students pursuing associate's or bachelor's degrees, as well as approved workforce training programs. Awarded yearly for up to four years, recipients must maintain academic standards. Funding varies based on the Community Foundation's annual income, and the award covers tuition, housing, supplies, and other educational expenses.

The Bews Foundation Grants support charitable organizations in Idaho's Treasure Valley, focusing on various sectors including education, health, community enhancement, and the arts. Grants up to $10,000 require a simple letter, while larger requests must follow a formal application process. The foundation prioritizes local initiatives and will not accept applications for services outside the Treasure Valley, ensuring that funds directly benefit the community.

The Tribal Nature-Based Solutions Climate Bond 2026 Solicitation aims to support California Native American tribes by funding the return of ancestral lands, habitat restoration projects, and enhancing wildfire resiliency. With approximately $9.2 million available, this program encourages multi-benefit initiatives such as land acquisition and local assistance. Funds may be allocated for various purposes, including contracts and grants, promoting sustainable solutions that benefit both the environment and indigenous communities.

The Coach Kevin Ferguson Scholarship Endowment supports continuing education through scholarships, prioritizing students pursuing careers in Physical Education or those with a connection to the Prince George High School Baseball Team. Applicants must demonstrate academic achievement, community involvement, and financial need. The scholarship funds tuition, fees, and educational expenses, reinforcing Kevin Ferguson's legacy of fostering academic and athletic excellence among young athletes in the community. Applications are reviewed annually by the John Randolph Foundation.

The Essential Utilities Protect Your Drinking Water Grant, administered by the Pennsylvania Environmental Council, offers funding between $2,500 and $10,000 for projects aimed at protecting public drinking water sources. Eligible applicants include non-profits, municipalities, and educational institutions targeting priority water protection areas in Pennsylvania. Projects may involve green infrastructure, educational programs, and agricultural best practices. A 20% matching contribution is required, with initial funding of 90% provided upfront.

The Bobby Owen Memorial Scholarship Endowment supports students in Prince George County pursuing careers as firefighters, police officers, or emergency medical providers. Established in 2003 in memory of Bobby Owen, the scholarship aims to assist those who have volunteered in these roles or wish to pursue related training. Eligible applicants must demonstrate financial need and maintain a GPA of 3.0 or higher. All documents must be submitted online by the deadline to be considered.