Best Winston Salem Grants for Nonprofits in North Carolina

The NEA Arts and Artifacts International Indemnity Program, established in 1975, supports the exhibition of significant art and artifacts by minimizing insurance costs for international exhibitions. Administered by the National Endowment for the Arts, it covers U.S. owned art during exhibitions in the country. The program evaluates applications through advisory panels and the Federal Council on the Arts and Humanities, ensuring that vital cultural works are accessible while providing necessary financial protections.

The NEA Arts and Artifacts Domestic Indemnity Program, administered by the National Endowment for the Arts, ensures that U.S. museums can exhibit significant art and artifacts without the burden of high insurance costs. Established in 1975, it provides indemnity against loss or damage, promoting access to cultural heritage. The program evaluates applications through expert advisory panels and typically meets three to six months after deadlines to decide on indemnity requests, thereby supporting the arts and enriching public engagement.

The NEA Arts and Artifacts Domestic Indemnity Program provides museums and cultural institutions in the U.S. with financial protection against loss or damage to significant artworks during exhibitions. Established in 1975 and expanded in 2007, the program aims to enhance public access to art by minimizing insurance costs. Managed by the National Endowment for the Arts, it involves thorough evaluations by expert panels to ensure eligibility and compliance, facilitating the safe display of invaluable cultural treasures.

The National Institute of Environmental Health Sciences (NIEHS) is seeking applications for research coordination and data support under the Health and Extreme Weather initiative. This funding opportunity aims to engage NIH grantees and the broader community by sharing best practices, developing training resources, and facilitating access to health and environmental data. The initiative will enhance collaboration, reduce duplication, and promote data standards to support impactful research and infrastructure activities.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

NC DEQ 319 Grant Program

Through Section 319(h) of the Clean Water Act, the U.S. Environmental Protection Agency provides states with funding to reduce nonpoint source pollution. North Carolina typically receives around $1 million for competitive funding of watershed restoration projects. Funds may be used to conduct watershed restoration projects such as stormwater and agricultural best management practices and restoration of impaired streams. Section 319 grant projects must be used to help restore waterbodies currently impaired by nonpoint source pollution in areas with approved watershed restoration plans. (map) (list)

State and local governments, interstate and intrastate agencies, public and private nonprofit organizations, and educational institutions are all eligible to apply for 319 funding. An interagency workgroup reviews the proposals and selects those of merit to be funded. 

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

• Training programs
• Programs that engage new adopters and grow the market share for adoption
• Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
• Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

• Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
• Decrease length of stay
• Decrease cost of care
• Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.

NC Supportive Housing Development Program (SHDP)

The North Carolina Housing Finance Agency offers several programs to help nonprofit organizations and local government entities build and rehabilitate emergency, transitional, and permanent housing for people who are experiencing homelessness or at imminent risk of homelessness, have disabilities or other special needs.

The Supportive Housing Development Program (SHDP) aims to increase the supply of emergency, transitional and permanent supportive housing for special populations and low-income households.

Supportive Housing Development Program-Veterans (SHDP-Veterans)

New for the 2026 cycle, SHDP-Veterans financing is available for acquisition, rehabilitation, and/or new construction of emergency, transitional, or permanent housing serving veterans who are homeless or imminently at risk of homelessness.

The housing must serve households who earn below 50% of area median income. Rent and utilities cannot exceed 30% of the gross household income. 

NC Supportive Housing Development Program (SHDP)

The North Carolina Housing Finance Agency offers several programs to help nonprofit organizations and local government entities build and rehabilitate emergency, transitional, and permanent housing for people who are experiencing homelessness or at imminent risk of homelessness, have disabilities or other special needs.

The Supportive Housing Development Program (SHDP) aims to increase the supply of emergency, transitional and permanent supportive housing for special populations and low-income households.

Supportive Housing Development Program-Integrated (SHDP-Integrated)

New for the 2026 cycle, SHDP-Integrated financing is available for acquisition, rehabilitation, and/or new construction of permanent rental housing serving people with disabilities in an integrated setting.

The housing must serve households who earn below 50% of area median income. Rent and utilities cannot exceed 30% of the gross household income. 

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

• The tools, templates and training they need to start right away;
• A shared brand they can plug into on day one;
• A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

Department of Health and Human Services 

The Department of Health and Human Services manages the delivery of health and human related services for all North Carolinians, especially our most vulnerable people – children, elderly, disabled and low-income families. The department works closely with health care professionals, community leaders and advocacy groups; local, state and federal entities; and many other stakeholders to make this happen.

Community Services Block Grant

The Community Services Block Grant is the sole source of federal funding for North Carolina’s Community Action Agencies that provide a wide range of services and programs to assist needy families with children. CSBG funding supports projects that:  

• Decrease poverty in communities.
• Address the needs of low-income individuals, including the homeless, migrants and the elderly.
• Provide services and activities addressing employment, education, better use of available income, housing, nutrition, emergency services and/or health.

The CSBG State Plan is required for North Carolina to receive CSBG block grant funds, and it describes major program provisions, eligible entities, training and technical assistance, and program benefits.

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

The National Institute of Environmental Health Sciences (NIEHS) is launching a funding opportunity for research hubs focused on the health impacts of extreme weather. This initiative encourages multidisciplinary teams to engage with community partners on issues such as wildfire smoke and extreme heat. Emphasizing collaboration, the program aims to develop scalable solutions and measurable public health outcomes, leveraging resources and expertise across institutions to address climate-related health challenges effectively.

The Mary Eliza Mahoney Scholarships, offered by the Minnesota Nurses Association Foundation (MNAF), provide financial support to nursing students, members of healthcare unions, their dependents, and veterans. Each scholarship awards $2,500 per semester for a maximum of four semesters, totaling up to $10,000. This initiative aims to enhance nursing education and promote the professional growth of future nurses, ensuring access to quality healthcare for all.

Who We Are

Community foundations began nationally in 1914 and are publicly-supported, 501(c)(3) philanthropic organizations that hold, administer, invest and make grants from both endowed and non-endowed funds established by individuals, families and others. They were designed to be simple, flexible, convenient, tax-wise, cost-effective and perpetual charitable vehicles.  

Our Community Foundation was established in Roanoke in 1988. With our growth, we expanded into the Martinsville/Henry County area in 2005. Today, we administer many hundreds of named endowment funds ranging in size from a minimum of $10,000 to millions of dollars. To date, donors have also committed very significant resources to the Foundation through future estate gifts.

Information for Scholarship Seekers

Community Foundation Serving Western Virginia, the region’s community foundation, administers a variety of scholarships to reward and assist capable and deserving students based on the criteria established by the fund donors.

Specifics of the Foundation’s scholarship program may be subject to change from time to time. If you have any questions or need additional information, please contact the Foundation at (276) 656-6223.

Ashby C. and John T. Pinkard Scholarship Fund

 Fund provides higher education scholarships to deserving young men and women.

The Benny Summerlin Scholarship Fund, managed by the Community Foundation Serving Western Virginia, offers financial assistance to deserving students from Franklin County High School pursuing undergraduate degrees. Established to support capable individuals, this scholarship emphasizes academic potential and financial need. The foundation, active since 1988, administers various scholarships to uplift the educational aspirations of local youth. For more information on eligibility and application processes, interested students should contact the foundation directly.

The Kelsey Nicole Cooper Scholarship Fund, administered by the Community Foundation Serving Western Virginia, offers scholarships to deserving students from the Martinsville Henry County community, emphasizing volunteerism. Eligible applicants must be graduating seniors or graduates from local high schools, enrolled or planning to enroll in accredited colleges, and maintain a minimum GPA of 2.5. Preference is given to those attending Virginia Tech or involved in the CHILL youth task force. For more information, contact the Foundation.