Infrastructure and Workforce Grants for Appalachia from ARC
Nonprofit organizations, public agencies, tribes, and higher education institutions in eligible Appalachian counties in North Carolina can seek funding to improve critical infrastructure and strengthen business and workforce development. The Appalachian Regional Commission’s Area Development Program supports projects like water and wastewater systems, transportation, broadband, entrepreneurship, worker training, and related community capacity-building across the region.
Appalachian Regional Commission
Community Impact Grants for Nonprofits from Triangle Community Foundation
Nonprofit organizations working on community well-being, youth enrichment, or education in North Carolina and other Clancy & Theys regions can apply for grants up to US $10,000 to strengthen local services and quality of life. North Carolina healthcare access and related social service programs may be eligible for support from Triangle Community Foundation’s Clancy & Theys 1949 Fund.
Triangle Community Foundation
North Carolina Community Programs Funding via US Bancorp Foundation
Nonprofit 501(c)(3) organizations in North Carolina working on economic and workforce advancement, safe and affordable housing, or community arts and culture can seek support for community programs. Focused on equitable, high-impact funding, US Bancorp Foundation prioritizes groups advancing diversity, equity, and inclusion, especially those led by people of color and serving designated U.S. Bank communities.
US Bancorp Foundation
Creag Foundation Support for Innovative Healthcare
Nonprofit 501(c)(3) organizations with innovative human services or health care access and delivery programs in North Carolina can seek support to address pressing social problems. Grants from Creag Foundation help smaller or evolving organizations test new approaches to existing or previously unaddressed issues; funding is by invitation, starting with a letter of inquiry.
Creag Foundation
North Carolina Youth Services Funding via Dan Paul Foundation
Nonprofit 501(c)(3) organizations supporting youth health, education, and welfare in North Carolina can seek up to US $15,000 for direct-service programs. The Dan Paul Foundation supports child advocacy, homelessness and poverty services, early childhood development, environmental education, and refugee enrichment, which may benefit healthcare-related initiatives serving children and youth.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants for Healthcare
With a mission to support early-stage social impact organizations, Draper Richards Kaplan Foundation provides North Carolina nonprofit and impact-first healthcare innovators with capacity-building support and up to US $300,000 over three years. Organizations must be post-pilot, under 10 years old, scalable beyond place-based models, and focused on underserved communities, with operations in the U.S. or other priority regions.
Draper Richards Kaplan Foundation
North Carolina Economic Empowerment Funding via Cisco Systems Foundation
Nonprofit and nongovernmental organizations using technology for crisis response, education access, or economic empowerment projects that serve mostly economically underserved communities, including in North Carolina, can apply for Global Impact Cash Grants, with awards up to US $100,000. Grants from Cisco Systems Foundation help innovative, tech-enabled programs scale impact through early-stage solution development.
Cisco Systems Foundation
William Randolph Hearst Foundation Culture Grants in North Carolina
Nonprofit cultural institutions in North Carolina offering arts or science programs can apply for more than US $100,000 to support program, capital, or limited general and endowment needs. William Randolph Hearst Foundation prioritizes large, well-established U.S. 501(c)(3) organizations engaging youth, developing artistic talent, or advancing STEAM education, which may include health-related education components.
William Randolph Hearst Foundation
Michael & Susan Dell Foundation Support for Health
North Carolina nonprofit healthcare programs serving urban low-income children and youth may be eligible for project or scale-up funding over US $50,000, especially in health and wellness. North Carolina health care access organizations can access funding through the Michael & Susan Dell Foundation, which supports education, health, and family economic stability initiatives in the U.S., India, and South Africa.
Michael & Susan Dell Foundation
Community and Education Funding from Amgen Foundation
Nonprofit organizations and eligible public or governmental entities supporting humanitarian, social, education, or community programs in North Carolina or nationwide can seek non-healthcare donations and sponsorships for charitable initiatives. With a mission to strengthen communities, Amgen Foundation provides funding to U.S.-based 501(c)(3) charities and similar qualified organizations, which may benefit nonprofits that also operate healthcare-related community programs.
The Amgen Foundation Inc
Obici Healthcare Foundation Grants for North Carolina Health Programs
Nonprofit 501(c)(3) organizations and public entities improving community health in North Carolina’s Gates County can seek US $500 - US $5,000 for programs that boost wellness, physical activity, health awareness, or access to critical resources. Focused on community health, Obici Healthcare Foundation invites collaborative, innovative projects; applications are accepted on a rolling basis until funds are exhausted.
Obici Healthcare Foundation
State Employees Credit Union Foundation Support for Healthcare
Nonprofit and governmental organizations in North Carolina seeking funding for high-impact healthcare, housing, education, or human services projects can apply for SECU Foundation grants. Focused on capital, programmatic, and capacity-building initiatives, the State Employees Credit Union Foundation favors tangible projects with regional or statewide reach that strengthen communities and public employees.
State Employees Credit Union Foundation
Health and Human Services Grants from Semnani
Nonprofit organizations providing health care access, humanitarian aid, or social services can apply for support from the Semnani Family Foundation, which funds programs in the U.S. and internationally. Grants focus on healthcare access and delivery, disaster relief, women’s and children’s health, and other services that may benefit North Carolina healthcare-focused nonprofits working with marginalized communities.
Semnani Family Foundation
North Carolina Health Funding via Sidney Stern Memorial Trust
North Carolina nonprofit healthcare and health access programs can access funding through the Sidney Stern Memorial Trust for charitable, medical, scientific, or educational work benefiting U.S. communities. Eligible applicants are 501(c)(3) organizations with tax-exempt status; funded activities must occur within the U.S. and demonstrate broad, meaningful impact on their target populations.
Sidney Stern Memorial Trust
Healthcare and Community Funding for Carolinas Nonprofits via Van Every Foundation
Full proposal due Aug 10, 2026
Nonprofit 501(c)(3) organizations in North Carolina seeking support for healthcare, rehabilitation, human services, education, or arts projects and capital needs may be eligible for grants of US $10,000 - US $50,000 from the Philip L Van Every Foundation. Focus areas include health care access and delivery, wellness, prevention, substance abuse, and medical rehabilitation in North and South Carolina.
Philip L Van Every Foundation
Storytelling and Wellness Funding from Jesse W Couch Charitable Foundation
Applications due Sep 25, 2026
Nonprofit 501(c)(3) organizations and aligned for-profits in North Carolina can seek more than US $50,000 to tell impactful stories about their preservation, education, or wellness work. Jesse W Couch Charitable Foundation supports projects such as mental health, wellness, outdoor access, and related community programs through its Storytelling Grant, which helps showcase real-world outcomes.
Jesse W Couch Charitable Foundation
Walnut Cove Members Association Grants for Healthcare
Applications due Sep 26, 2026
Nonprofit 501(c)(3) organizations serving Western North Carolina residents with social or healthcare services can seek US $10,000 - US $25,000 for programs addressing basic needs like food, shelter, and health care. Walnut Cove Members Association also supports youth education and certain natural, cultural, or animal welfare initiatives benefiting low-income communities.
Walnut Cove Members Association Inc
Health and Human Services Funding from Robinson Foundation
Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations providing medical assistance, health services, or related support in North Carolina and the broader Southern region can seek funding for single-year projects. Grants from Robinson Foundation help established charities (3+ years) addressing health, poverty relief, children and families, veterans, disaster relief, and related humanitarian needs, excluding capital projects.
Robinson Foundation
North Carolina Community Services Funding via Insperity
Applications due Oct 16, 2026
Nonprofit 501(c)(3) organizations offering community services in North Carolina, especially where Insperity employees live and work or where Insperity is a client, may be eligible for philanthropic grants or event sponsorships. Insperity provides financial, volunteer, or in-kind support to help approved charities meet important service, fundraising, and community goals once per year.
Insperity
Dudley T Dougherty Foundation Grants for North Carolina Community Services
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding in North Carolina can seek project support through the Dudley T Dougherty Foundation. With a mission to foster positive change, the foundation provides funding that may benefit nonprofits whose healthcare programs intersect with community or environmental well-being.
Dudley T Dougherty Foundation Inc
Youth and Basic Needs Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near TJX locations in North Carolina can apply for TJX Foundation grants to support basic needs, youth education, workforce readiness, and safety from domestic violence. Eligible health-related programs serving vulnerable families and children may benefit, provided they meet the mission, distance, and nondiscrimination requirements and have not received TJX funding in the past year.
The Tjx Foundation Inc
Duke Endowment Child Welfare Grants in North Carolina
Pre proposal due Dec 15, 2026
Grants from The Duke Endowment help North Carolina child- and family-serving nonprofits fund implementation support for evidence-based programs addressing child abuse, neglect, and family well-being. Accredited organizations with two years of audited financials, including residential and foster care providers, may apply through a required pre-application process; South Carolina agencies are also eligible.
The Duke Endowment
Dr Scholl Foundation Health Grants in North Carolina
Letter of inquiry due Jan 31, 2027
North Carolina 501(c)(3) nonprofits running health care access and delivery programs can access funding through the Dr Scholl Foundation; awards range from US $5,000 - US $25,000 for one year of support. Organizations may also be considered if they work in related areas such as education, social services, civic and cultural, or environmental projects.
Dr Scholl Foundation
Camber Foundation Grants for North Carolina Health
Applications due Feb 27, 2027
Nonprofit 501(c)(3) organizations and fiscally sponsored programs improving health and wellness in Eastern North Carolina can apply for US $25,000 - US $50,000 grants to support healthcare access, mental health, and related services. Camber Foundation also funds education, workforce development, entrepreneurship, and digital opportunity through one-year general operating or program-specific awards.
Camber Foundation
Health and Human Services Funding from Underdown Family Foundation
Applications due Apr 30, 2027
Nonprofit 501(c)(3) organizations providing health, human services, education, or faith-based programs in Hickory, North Carolina can seek support to enrich the local community. Grants from Underdown Family Foundation help North Carolina healthcare and related service providers address community needs, with a strong preference for projects maximizing impact in the Hickory area.
Underdown Family Foundation
Chick Fil A Foundation Grants for Youth
Applications due May 1, 2027
Nonprofit 501(c)(3) organizations in North Carolina working on youth education, housing, hunger, or environmental programs can apply for Chick Fil A Foundation’s True Inspiration Awards, with grants of US $30,000 - US $350,000. Health-focused nonprofits serving underserved youth and families through food security, healthy habits, or supportive community services may be especially competitive.
Chick Fil A Foundation Inc
Nantahala Health Foundation Support for Youth Well-Being
Pre proposal due May 30, 2027
Nonprofit organizations, government units, tribal governments, and eligible businesses in western North Carolina can seek funding to launch, grow, or scale youth and young adult well-being programs. With a mission to improve regional health, Nantahala Health Foundation provides North Carolina healthcare and education initiatives up to US $50,000, prioritizing underserved youth and collaborative partnerships.
Nantahala Health Foundation