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Best Beaufort County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Beaufort County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Charleston County, Greenville County, and Richland County.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,267 Results based on applied filters

Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) (355586)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MOSAIC Postdoctoral Career Transition Award (K99/R00) aims to support early career independent investigators from diverse backgrounds in NIH mission areas. This program enhances diversity in the biomedical sciences research workforce by facilitating transitions from mentored postdoctoral positions to independent faculty roles. Awardees will receive NIH research support to launch competitive careers and will engage in mentoring, networking, and professional development activities as part of a scientific cohort.
Diversity, Equity & Inclusion Science Health & Medicine +2 more

Philip & Louise Wang Scholarship Fund

Hawai'i Community Foundation
Private
Hawaii, United States
Unspecified amount
The Philip & Louise Wang Scholarship Fund, established by the Hawai‘i Community Foundation in 2022, aims to support U.S. residents who demonstrate financial need, academic merit, and good character while attending accredited post-high school institutions. Eligible applicants must be Hawaii residents maintaining a minimum GPA of 2.0. Preference is given to first-generation college students and previous recipients who continue to meet eligibility criteria. This initiative embodies our vision of a thriving and equitable Hawai‘i.
Academic Success & Enrichment

Shigeo and Winifred Ito Scholarship Fund

Hawai'i Community Foundation
Private
California, Colorado +11 more
Approximately US $6,000
The Shigeo and Winifred Ito Scholarship Fund, established by a former recipient of the Hawai‘i Community Foundation, aims to support students from Hawaii pursuing higher education on the U.S. mainland. With awards averaging around $6,000, the fund prioritizes residents demonstrating financial need and maintaining good academic standing. The scholarship reflects a commitment to fostering educational opportunities and giving back to the community, ensuring that deserving students can achieve their academic goals.
Education - Higher Education

Pat Shinobu Scholarship Fund

Hawai'i Community Foundation
Private
United States
Unspecified amount
The Pat Shinobu Scholarship Fund, established in 2015 by the Hawai‘i Community Foundation, aims to support students from Hawai‘i pursuing higher education. Eligible applicants must be full-time undergraduate students with a minimum GPA of 2.7, demonstrate financial need, and provide a recommendation letter. Preference is given to public high school graduates from Hawai'i Island and previous recipients who maintain eligibility. This fund fosters educational opportunities and equity within the community.
Academic Success & Enrichment Academic Scholarship Programs

S&G Labs Hawaii Scholarship Fund

Hawai'i Community Foundation
Private
United States
Approximately US $6,000
The S&G Labs Hawaii Scholarship Fund, established by the Hawai‘i Community Foundation in 2018, aims to support students transitioning from drug treatment into educational training. Applicants must be Hawaii residents with financial need, maintaining a minimum GPA of 2.5, and enrolled full-time in an accredited institution. Average awards are around $6,000, depending on available funds and applicant qualifications. This initiative fosters equity and opportunity for vulnerable communities in Hawaii.
Education - Higher Education

Sons and Daughters Scholarship Program

Cleveland Cliffs Foundation
Private
Canada, United States
US $3,000
The Sons and Daughters Scholarship Program, administered by the Cleveland-Cliffs Foundation, offers a competitive scholarship of $3,000 annually for up to four years for undergraduate studies. This initiative recognizes exceptional academic and extracurricular achievements among high school students. Scholarships are available to those attending accredited colleges or universities in the U.S. or Canada, though children of Cleveland-Cliffs officers are ineligible. The program aims to enhance educational opportunities and support community growth.
Academic Scholarship Programs

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health Pharmacology Drug Safety +1 more

Rita Allen Foundation: Scholars Award in Pain

Rita Allen Foundation
Private
Canada, United States
US $150,000
The Rita Allen Foundation: Scholars Award in Pain supports early-career researchers in basic pain science. Established in 2009, it offers grants of $150,000 over three years to those investigating innovative pain mechanisms and analgesic development. Eligible candidates should be in the early stages of their faculty careers, demonstrating exceptional promise and a commitment to pain research. This award aims to enhance understanding and treatment of chronic pain, fostering impactful scientific advancements.
Anesthesia and Pain Medicine

Ken W. Davis Foundation Grant

Ken W Davis Foundation
Private
United States
More than US $10,000
The Ken W. Davis Foundation Grant provides essential funding to nonprofit organizations in the U.S. that align with the Foundation's mission of promoting basic human needs and education in line with Constitutional freedoms. With a minimum grant size of $2,500, the Foundation focuses on supporting human service organizations in Tarrant County, Texas, and the Permian Basin of West Texas and Southeast New Mexico, while also offering national support for grants related to Constitutional freedoms.
Governance & Democracy Human & Social Services Education System Policy & Reform

Apprenticeship Program

Alliance for California Traditional Arts
Private
United States
US $5,000
The ACTA Apprenticeship Program has been supporting California's cultural traditions for nearly 25 years by providing $5,000 contracts to mentor artists for intensive training of eligible apprentices. This program fosters the continuity of traditional arts through one-on-one mentorship, culminating in public presentations and documentation of the learning process. Eligible applicants must submit a collaborative application, demonstrating commitment and quality in their respective art forms. This initiative not only preserves cultural practices but also enhances community engagement.
Art & Culture Art Education

Igor Gorin Memorial Award

Community Foundation for Southern Arizona
Private
United States
Up to US $12,000
The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.
Opera

Community Collaboration Challenge

National Partnership for Student Success
Association/Society
United States
US $5,000 - US $10,000

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

Tutoring & Mentoring College Success / Persistence

Smart Family Fund

Smart Family Fund
Private
United States
US $25,000 - US $100,000
The Smart Family Fund is a private foundation dedicated to supporting early-stage non-profits that demonstrate the potential for scalable, positive impact. With grants ranging from $25,000 to $100,000, they aim to assist organizations in refining their models and preparing for larger investments. The foundation, guided by three brothers, focuses on mentoring and backing social entrepreneurs facing challenges in securing funding for innovative yet untested ideas, fostering a brighter future for communities.
All fields of work Nonprofit Growth & Development

The Rona Jaffe Foundation Fellowship

Fine Arts Work Center in Provincetown
Private
United States
More than US $2,500
The Rona Jaffe Foundation Fellowship supports emerging women writers with a fully funded 7-month residency at the Fine Arts Work Center. Established by the Rona Jaffe Foundation, it includes a $2,500 prize to assist with travel and living expenses. Eligible candidates must be U.S. residents, at least 18 years old, and not enrolled in a degree program during the fellowship year. This prestigious fellowship aims to nurture exceptional literary talent.
Writing & Literature

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) (356879)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.
Human Genome & Genetics Rare Diseases

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.
Biomedical informatics Neurological Diseases & Disorders Musculoskeletal Diseases

Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) (356887)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Limited Competition: Basic Instrumentation Grant (BIG) Program, supported by the NIH, invites applications from institutions that have not received significant S10 funding in recent years. This program provides a minimum award of $25,000 and allows for a maximum of $350,000 to purchase specialized instruments essential for NIH-supported research. Eligible instruments include cell sorters, confocal microscopes, and more, promoting advancements in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (356886)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Shared Instrumentation Grant (SIG) Program supports NIH investigators in acquiring high-cost, specialized instruments essential for research. With a minimum award of $50,000 and a maximum of $750,000, this program facilitates the purchase or upgrade of equipment like mass spectrometers and light microscopes. It encourages collaborative efforts among researchers to enhance capabilities and foster innovation in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) (356883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The High-End Instrumentation (HEI) Grant Program, funded by the NIH, supports NIH-supported investigators in acquiring high-end, specialized instruments. With a minimum award of $750,001 and a maximum of $2,000,000, this program aims to enhance research capabilities. Eligible instruments include nuclear magnetic resonance spectrometers, mass spectrometers, and advanced imaging systems, among others. Applications are due by 5:00 pm local time of the applicant organization.
Medical Technology, Devices, and Equipment Health & Medicine Biotechnology +1 more

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) (356888)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.
Biomedical informatics Epidemiology & Public Health Health Information Technology

Reboot Representation Grant

Reboot Representation Tech Coalition
Association/Society
United States
Unspecified amount
The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.
Computer Science & Engineering Diversity, Equity & Inclusion Women's Rights & Equality +4 more

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This funding opportunity aims to enhance understanding of chemical-induced skin injuries, particularly those recognized as public health threats. The initiative encourages research focused on identifying commonalities in these injuries and exploring shared signaling pathways. By investigating therapeutic targets, this program seeks to develop effective medical countermeasures. Multiple application deadlines are set from 2025 to 2027, supporting diverse research proposals in this crucial area.
Environmental Chemistry & Toxicology Wounds & Injuries Burn Care

Whole Foods Market Store Giving Program

Whole Foods Market
Corporate
Canada, United Kingdom +1 more
Unspecified amount
The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.
Food Access & Hunger Environmental Stewardship

Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR is inviting applications for the continuation or revision of ongoing clinical trials through the UH3 Clinical Trial Required grant. This opportunity supports extensions for completing trials or longer follow-up periods, as well as revisions that are well justified. Key deadlines for submissions are set from March 2025 to January 2028, with optional Letters of Intent encouraged thirty days prior to application due dates. Ensure compliance with the outlined requirements to enhance your chances of funding.
Dental Health

Wildlife Annual Grants - Established Investigator ( Avian/Fish/Invertebrates)

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Approximately US $100,000
Morris Animal Foundation invites Established Investigators to submit pre-proposals for research focused on reptile and amphibian health. This initiative emphasizes the importance of animal health and welfare while facilitating impactful conservation efforts. Proposals must demonstrate clear animal health needs, collaborative strategies, and potential benefits to wildlife populations. Funding for these projects is anticipated to average around $100,000 over a maximum duration of 36 months, fostering innovative solutions for pressing health challenges in these species.
Herpetology Wildlife Health

Beaufort County Grants for Nonprofits Highlights

Looking for Beaufort County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Beaufort County grants recommended for your specific programs in South Carolina.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Beaufort County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Beaufort County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Beaufort County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081