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Best Beaufort County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Beaufort County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Charleston County, Greenville County, and Richland County.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,267 Results based on applied filters

Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Tobacco, Alcohol, and Cannabis Policy Research for Health Equity grant aims to support research on policies affecting tobacco, alcohol, and cannabis use in the U.S. This initiative focuses on how these policies impact populations facing health disparities. Key components include engaging community organizations to advance equity in cancer prevention. Important deadlines for applications range from February 2025 to October 2027, providing opportunities for both standard and renewal submissions.
Alcoholism Smoking Health Disparities & Social Determinants of Health +2 more

Vilcek Foundation Grants

The Vilcek Foundation Inc
Private
American Samoa, Guam +4 more
US $5,000 - US $20,000
The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.
Immigrant Services Art & Culture Education - Higher Education +1 more

Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed) (357113)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Technology Development Research for Establishing Feasibility and Proof of Concept (R21) grant supports innovative projects aimed at developing new technologies with high potential impact in biomedical research. Applicants are encouraged to submit Letters of Intent 30 days before application deadlines, which are set for February, June, and October from 2025 to 2027. This funding opportunity is administered by the NIH, focusing on high-risk, high-reward exploratory research.
Biotechnology Emerging Technology Development Medical Technology, Devices, and Equipment +1 more

Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (357112)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Focused Technology Research and Development (R01) grant supports innovative projects aimed at developing technologies to enhance biomedical research. This funding opportunity emphasizes the creation of laboratory instruments, algorithms, and biological systems that can significantly improve research capabilities. Key deadlines for applications are set for February, June, and October of 2025 through 2027, ensuring ample time for proposal submissions. The initiative is funded by the National Institutes of Health (NIH), part of the US Department of Health and Human Services.
Biotechnology Biomedical Imaging Medical Technology, Devices, and Equipment +1 more

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional) (356925)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This grant opportunity from the NIH aims to enhance mechanistic research on precision probiotic therapies through a biphasic R61/R33 award mechanism. It encourages innovative studies to identify specific biological factors influencing probiotic responses, thereby improving clinical outcomes. The program supports up to five years of research, with the initial phase focused on discovering unique host characteristics and the second phase assessing improvements in probiotic efficacy through rigorous studies.
Integrative & Alternative Health Microbiomes

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) (356927)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,400,000
This funding opportunity aims to advance mechanistic research for precision probiotic therapies. It invites R33 applications focused on characterizing individual differences in probiotic responses, identifying responder subgroups, and enhancing clinical outcomes. The goal is to develop strategies addressing barriers to effective probiotic use, accounting for human variability. Proposals should include innovative studies using animal models or human subjects, supported by preliminary data to test biological patterns and their effects on health outcomes.
Biology Microbiology Microbiomes

Extramural Discovery Science Accelerator Award

American Cancer Society
Association/Society
United States
Up to US $75,000
The Extramural Discovery Science Accelerator Award supports the commercialization of ongoing cancer research projects, focusing on experiments that facilitate technology validation and de-risking. Applications are accepted on a rolling basis, with a budget of up to $75,000 for one year. This award encourages independent investigators at any career stage to advance their technologies, with a strong emphasis on commercial viability and collaboration within a learning community.
Cancer / Oncology Medical Technology, Devices, and Equipment

Leukemia Exploration and Prevention Grant Program (LEAP) - Team Award

American Cancer Society
Association/Society
United States
Up to US $1,720,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention for patients with RUNX1 familial platelet disorder (RUNX1-FPD). This program supports interdisciplinary research teams investigating the mechanisms of leukemogenesis and innovative treatment strategies. With funding of up to $430,000 per year, LEAP encourages projects focused on both understanding clonal evolution and developing novel therapeutic approaches. The initiative seeks to bridge critical knowledge gaps and provide urgent interventions for high-risk populations.
Leukemia

Leukemia Exploration and Prevention Grant Program (LEAP) - Research Scholar Grant

American Cancer Society
Association/Society
United States
Up to US $860,000
The Leukemia Exploration and Prevention Grant Program (LEAP) aims to advance cancer interception and prevention strategies for patients with RUNX1 familial platelet disorder. This initiative, supported by the American Cancer Society, focuses on understanding the mechanisms behind leukemia development and fostering innovative research leading to effective treatment options. Grants of up to $215,000 per year for four years are available, emphasizing the urgent need for targeted therapies in high-risk populations.
Leukemia

Green Chemistry Student Chapter Award

American Chemical Society
Association/Society
United States
Unspecified amount
The Green Chemistry Student Chapter Award recognizes ACS student chapters for their commitment to green chemistry initiatives. This award highlights the importance of green chemistry in education, encouraging students to engage in activities that promote sustainability. Eligible chapters must submit detailed summaries of at least three green chemistry projects, demonstrating their understanding of the principles and practices that contribute to a more sustainable future.
Chemistry

CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) (356935)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The CCRP Initiative invites applications for basic research on chemical threats affecting the nervous system, including chemical warfare agents and toxic industrial chemicals. This funding aims to elucidate toxicity mechanisms, explore new toxic exposure manifestations, and identify targets for therapeutic development. Proposals should generate data relevant to understanding these toxic threats, with applications due by 5 PM local time. Optional Letters of Intent are encouraged 30 days prior to the proposal deadline.
Neuroscience Environmental Chemistry & Toxicology Neurological Diseases & Disorders

USF: Community Impact Grant

Usa Swimming Foundation
Private
United States
Up to US $5,000
The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.
Swimming

USF: HBCU Grant

Usa Swimming Foundation
Private
United States
US $5,000 - US $10,000
The USA Swimming Foundation's HBCU Grant program is a $1 million initiative aimed at enhancing swimming opportunities in communities served by Historically Black Colleges and Universities (HBCUs). Launched in 2021, the program provides annual grants of $100,000 over ten years, supporting youth water safety lessons and university swim clubs. This initiative is designed to empower HBCUs to expand their aquatic programming, fostering inclusivity and safety in swimming across diverse communities nationwide.
Black American Services Swimming Diversity, Equity & Inclusion

USF: Youth Learn-to-Swim Grant

Usa Swimming Foundation
Private
United States
Unspecified amount
The USA Swimming Foundation's Youth Learn-to-Swim Grant aims to increase access to swim lessons for children across the nation. By providing funding to swim lesson programs, the foundation ensures that financial barriers do not prevent children from learning this vital life skill. Grants can be used for free or reduced-cost lessons, addressing the needs of underserved communities and promoting safety through swimming education.
Swimming Diversity, Equity & Inclusion

USF: Adult Learn-to-Swim Grants

Usa Swimming Foundation
Private
United States
US $1,000 - US $5,000
The Adult Learn-to-Swim Grants, offered by the USA Swimming Foundation in collaboration with U.S. Masters Swimming, aim to enhance swimming safety for adults aged 18 and over. This initiative provides funding to programs that promote swim education, targeting underserved communities. Grants can be used for expenses like pool rentals and scholarships, with a maximum award of $5,000. The goal is to reduce drowning risks and encourage ongoing participation in swimming activities.
Swimming

Steve's Foundation Grant

Achelis Foundation
Private
United States
US $500 - US $5,000
Steve's Foundation Grant is a small private funding opportunity providing grants between $500 and $5,000, averaging $2,600. It supports organizations that empower disadvantaged individuals, focusing on cost-effective programs that yield significant impacts. The foundation prioritizes proposals from non-profits that directly assist those in need, especially children and marginalized communities. Applications are evaluated annually in May or June, but due to high demand, the foundation cannot respond to every inquiry.
Youth Services Women & Girl Services Poverty Alleviation & Services +2 more

Puffin Foundation: Annual Artist Grant Program - Odd Year Focus

Puffin Foundation Ltd
Private
United States
Up to US $3,500
The Puffin Foundation's Annual Artist Grant Program, focused on odd years, supports individual artists and non-profit organizations in the genres of video/film and theater. Grants, typically around $1,750, aim to uplift marginalized voices in the arts. Applicants must be U.S. citizens or permanent residents with an SSN. The program excludes proposals in other disciplines and projects involving AI. This initiative prioritizes diverse artistic expression and aims to maximize funding impact for those with limited financial resources.
Theater Media Arts

Annual Artist Grant Program - Even Year Focus

Puffin Foundation Ltd
Private
United States
Up to US $3,500
The Puffin Foundation's Annual Artist Grant Program focuses on supporting artists and organizations that are often marginalized. In even years, proposals are accepted in fine arts, music, and photography. With a maximum grant size of $3,500, it aims to empower individuals and groups with limited resources to flourish creatively. This initiative reflects the Foundation's commitment to ensuring diverse artistic expressions thrive in society. Applicants must be U.S. citizens or residents, and only one proposal is permitted per year.
Music Fine Art Photography

NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens, building on the National Antimicrobial Resistance Monitoring System initiated by the FDA in 1996. This program seeks to improve detection of antibiotic-resistant bacteria in food commodities and expand sampling sites. By strengthening monitoring efforts, it aims to protect public health and achieve measurable outcomes aligned with NARMS objectives, contributing to national efforts against antibiotic resistance.
Veterinary Science & Services Animal Food & Drug Safety

Bolger Foundation Grant

Bolger Foundation
Private
United States
US $10,000 - US $250,000
The Bolger Foundation Grant is dedicated to supporting capital projects that enhance tangible property for 501(c)(3) nonprofit organizations. Grants range from $10,000 to $250,000, with a maximum project budget of $2.5 million. The foundation focuses on community empowerment through conservation, health, and education, while excluding revenue-generating and operational costs. Eligible organizations must adhere to strict compliance with federal tax regulations. The mission is to inspire and empower nonprofits to better serve their communities.
Environmental Conservation Health & Medicine Community Services +1 more

HVAC Skills Lab Grant - New Skills Lab

Explore The Trades
Private
Canada, United States
Up to US $25,000
The HVAC Skills Lab Grant aims to support middle and high schools in the U.S. and Canada by providing equipment and resources to establish plumbing and HVAC skills labs. With a growing demand for skilled trades, this program encourages educational institutions to equip students with vital trade skills. Grant recipients will receive $25,000 worth of products and equipment, along with access to SkillCat's technical training platform, fostering a new generation of skilled professionals.
Vocational & Trade Education Workforce Preparation & Job Readiness

HVAC Skills Lab Grant - Refurbish an Existing Plumbing or HVAC Skills Lab

Explore The Trades
Private
Canada, United States
Up to US $10,000
The HVAC Skills Lab Grant aims to refurbish existing plumbing and HVAC skills labs in middle and high schools across the U.S. and Canada. With a focus on preparing students for vital trade careers, the grant provides $10,000 in equipment to enhance hands-on learning. This initiative supports schools with technical training resources, promoting the growth of skilled labor in these essential fields. Schools that have not received a Skills Lab award in the past 24 months are eligible to apply.
Workforce Preparation & Job Readiness Vocational & Trade Education

Wexner Davidson Fellowship

Wexner Family Charitable Fund
Private
Canada, Mexico +1 more
Unspecified amount
The Wexner Davidson Fellowship (WDF) is a transformative leadership development program designed for Jewish communal professionals in North America aged 26-36. Over three years, Fellows engage in cohort-based learning at biannual institutes, receive coaching, and deepen their Jewish knowledge while building a strong professional network. This initiative fosters personal and professional growth, equipping the next generation of leaders to serve their communities effectively and connect with a global alumni network.
Jewish Culture Judaism

NCB - Botany Research Scholarship Program

Northern California Botanists
Association/Society
United States
US $1,500
The NCB - Botany Research Scholarship Program, offered by Northern California Botanists, targets undergraduate and graduate students pursuing research in botany and plant ecology. Scholarships of $1,500 support independent study, thesis, or dissertation projects within a specific geographic area of Northern California. Eligible applicants may reapply for funding for up to four years. This initiative aims to foster academic careers in botany and promote valuable ecological research.
Plant Science Ecology Botanical Conservation

Clinical and Translational Science Award (UM1 Clinical Trial Optional) (356316)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $6,500,000
The Clinical and Translational Science Award (CTSA) Program invites applications to enhance clinical and translational science through innovative partnerships and research programs. This initiative aims to accelerate the delivery of treatments to diverse populations by improving clinical research efficiency, creating national resources for public health responses, and providing training for clinical research professionals. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the full proposal deadline.
Science Health & Medicine Epidemiology & Public Health +1 more

NIA Advanced Postdoctoral Career Transition Awards to Promote Diversity in Translational Research for AD/ADRD (K99/R00 Clinical Trial Not Allowed) (356315)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Approximately US $100,000
The NIA Advanced Postdoctoral Career Transition Awards aim to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This initiative supports early career researchers from diverse backgrounds in acquiring essential research skills applicable to various AD/ADRD studies. The goal is to cultivate a more diverse pool of researchers capable of leading interdisciplinary approaches in treatment, prevention, and management of AD/ADRD. Notably, independent clinical trials are not permitted under this award.
Dementia & Alzheimer’s Disease Diversity, Equity & Inclusion Medical Education & Professional Training

Beaufort County Grants for Nonprofits Highlights

Looking for Beaufort County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Beaufort County grants recommended for your specific programs in South Carolina.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Beaufort County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Beaufort County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Beaufort County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081