Creag Foundation Grants for Delaware Innovation
Nonprofit 501(c)(3) organizations with innovative approaches to human services and social problems in Delaware can apply for Creag Foundation’s invitation-only funding; awards support new or unaddressed social issue strategies. Programs addressing health, community development, or disease-related challenges, including rare or respiratory diseases, may be eligible after holding 501(c)(3) status for at least one year.
Creag Foundation
Youth and Child Welfare Funding from Dan Paul Foundation
Nonprofit 501(c)(3) organizations worldwide serving children’s health, education, development, and welfare can apply for Dan Paul Foundation grants supporting youth enrichment, child advocacy, and basic needs. Delaware programs working with young people affected by serious or rare conditions may be eligible for funding up to US $15,000 for direct services and related initiatives.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants for Innovation
Delaware health and social impact organizations addressing respiratory or other serious diseases can access funding to scale innovative, proven solutions. Draper Richards Kaplan Foundation provides up to US $300,000 plus intensive capacity-building and community support for early-stage, impact-first nonprofits and mission-driven for-profits serving underserved populations in priority regions including the U.S.
Draper Richards Kaplan Foundation
Tech-Enabled Social Impact Funding from Cisco
Delaware nonprofits and NGOs using technology to tackle major social challenges can access funding through Cisco Systems Foundation’s Global Impact Cash Grants, with awards up to US $100,000. Programs must primarily serve economically underserved communities and focus on crisis response, education access, economic empowerment, or climate resilience, which may include health-related or rare disease–adjacent initiatives.
Cisco Systems Foundation
Community Safety and Development Grants from State Farm
Nonprofit 501(c)(3) organizations, educational institutions, government programs, and volunteer fire companies in Delaware can seek funding for safety, education, and community development initiatives from State Farm Companies Foundation. Projects such as disaster preparedness, home and auto safety, neighborhood revitalization, job training, and education programs may be eligible, including efforts that support people affected by rare diseases.
State Farm Companies Foundation
Hearst Foundation Support for Cultural Programs
U.S.-based 501(c)(3) cultural nonprofits with audited expenses over $2 million can seek more than US $100,000 to support arts and science programming. The Hearst Foundation funds program, capital, and limited general or endowment support for museums, performing arts organizations, arts schools, and similar institutions, including those in Delaware that engage youth or nurture artistic talent.
William Randolph Hearst Foundation
Delaware Health Funding via Labcorp Charitable Foundation
Delaware health and community nonprofits can seek support for healthcare access, education, and community initiatives through the Labcorp Charitable Foundation. Focused on health and welfare, the foundation invites U.S.-based 501(c)(3) organizations to apply for projects such as patient services, preventative healthcare, food pantries, and STEM education, which may benefit rare disease populations.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Grants for Education
Organizations working on education, children’s health, or family economic stability in Delaware and other eligible locations can apply for Michael & Susan Dell Foundation grants; awards are more than US $50,000 for project support or scaling. U.S. entities with a federal TIN, including nonprofits and social enterprises, may be eligible if they serve urban low-income children and youth.
Michael & Susan Dell Foundation
PNC Foundation Grants for Delaware Communities
Nonprofit 501(c)(3) organizations in Delaware communities where PNC has a significant presence can seek funding for early childhood education or community economic development initiatives. Grants from PNC Foundation help support programs for young children, affordable housing, small business development, community services, arts and culture, and revitalization in low- and moderate-income neighborhoods.
PNC Foundation
Delaware Community Programs Funding via Roche
Nonprofit charities in Delaware seeking support for humanitarian, social, educational, environmental, or contemporary arts projects can apply for Roche Corporate Donations and Philanthropy. Grants from Roche help Delaware organizations working on community development, science education, disaster response, or cultural initiatives that allow Roche to engage locally and use its expertise in partnership with accredited charities.
La Roche, Inc.
Health and Human Services Funding from Semnani
Delaware health and human services nonprofits addressing marginalized or vulnerable populations can access funding through Semnani Family Foundation for programs in health, education, and disaster relief. Organizations working on diseases and conditions, children’s and women’s health, healthcare access, or humanitarian aid may be eligible if their work aligns with the foundation’s global priorities.
Semnani Family Foundation
Delaware Health Funding via Sidney Stern Memorial Trust
Nonprofit 501(c)(3) organizations working on charitable, scientific, medical, or educational programs in Delaware can apply for support that must be used within the U.S. With a mission to strengthen broad-impact services, Sidney Stern Memorial Trust provides eligible organizations with funding that may benefit respiratory and rare disease initiatives among other health-related efforts.
Sidney Stern Memorial Trust
Bank of America Grants for Community Programs
Nonprofit 501(c)(3) organizations in Delaware can apply for Bank of America Charitable Foundation’s sponsorship support to advance economic mobility and social progress. Funding may benefit programs in housing, workforce development, hunger relief, community development, arts and culture, environment, and diversity and inclusion, including initiatives that intersect with rare or respiratory disease needs.
Bank Of America Charitable Foundation Inc
Hansen Family Foundation Community Impact Grants
Applications due Sep 11, 2026
U.S.-based 501(c)(3) nonprofits, including those in Delaware, can apply for Hansen Family Foundation grants of US $1,000 - US $10,000 to support children, education, animals, environment, humanitarian needs, and arts and culture. Smaller organizations with budgets under $1 million and reasonable overhead that serve vulnerable populations, including those affected by rare or serious diseases, may benefit.
Hansen Family Foundation
Storytelling and Conservation Funding from Jesse W Couch Foundation
Applications due Sep 25, 2026
Nonprofit 501(c)(3) and aligned for-profit organizations can receive more than US $50,000 to create storytelling projects that highlight their impact in areas like wildlife conservation, education, and wellness. Jesse W Couch Charitable Foundation funds U.S. organizations, so Delaware groups working on health, wellness, or related rare disease support may be eligible.
Jesse W Couch Charitable Foundation
Delaware Health Funding via Robinson Foundation
Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations providing health and medical assistance in Delaware and the broader Southern region can seek support for single-year programs. Robinson Foundation provides Delaware health-focused charities with funding that addresses medical assistance, poverty relief, children and families, disaster relief, and related services that may benefit people living with rare or serious diseases.
Robinson Foundation
Community Services Funding from Insperity
Applications due Oct 16, 2026
Delaware nonprofits providing community services, including those supporting people affected by rare diseases, can seek grants or event sponsorships that aid key service and fundraising goals. Focused on community involvement, Insperity invites 501(c)(3) organizations connected to its employees, client base, or local communities to apply once per year for philanthropic or sponsorship support.
Insperity
Dudley T Dougherty Foundation Grants for Delaware Community Services
Applications due Oct 31, 2026
Delaware nonprofit 501(c)(3) organizations seeking support for community services, environmental conservation, or peacebuilding projects can access funding through the Dudley T Dougherty Foundation. This national funder welcomes charitable initiatives that respect people, life, and the environment, which may include programs serving those affected by rare or chronic diseases.
Dudley T Dougherty Foundation Inc
Community Programs Funding for Nonprofits from Georgia-Pacific Foundation
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations, public schools, and qualified local government entities supporting education, entrepreneurship, environment, or community enrichment in Delaware communities near Georgia-Pacific facilities may be eligible for this funding. Georgia-Pacific Foundation supports projects that improve long-term well-being and sustainability in its manufacturing communities, which can include health or support services for people with rare or respiratory diseases.
Georgia-Pacific Foundation
Youth and Family Support Grants from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near a TJX location can apply for TJX Foundation grants to support basic needs, at-risk youth education, workforce readiness, and safety from domestic violence. Delaware health and rare disease nonprofits may be eligible if they meet the mission, distance, and nondiscrimination requirements and have not received TJX funding in the past year.
The Tjx Foundation Inc
Lawrence Foundation Grants for Delaware Environment
Applications due Nov 1, 2026
Delaware 501(c)(3) public charities, public schools, and libraries can access funding for environmental and human services programs, including those touching rare disease impacts, through the Lawrence Foundation; awards typically range from US $5,000 - US $10,000. This private family foundation offers unrestricted program or operating support with no geographic restrictions for U.S.-headquartered organizations.
Lawrence Foundation
Max and Victoria Dreyfus Foundation Grants for Delaware Community Programs
Applications due Nov 11, 2026
With a mission to help impactful community programs, Max and Victoria Dreyfus Foundation provides Delaware nonprofits with US $1,000 - US $20,000 for museums, arts, education, health facilities, environmental efforts, and social services. U.S.-based 501(c)(3) organizations, including those addressing respiratory and rare diseases within broader community or clinical programs, may be eligible.
Max and Victoria Dreyfus Foundation
Community Vitality Funding from Ameriprise Financial
Applications due Jan 15, 2027
U.S.-based 501(c)(3) nonprofits addressing basic needs, community development, cultural enrichment, or volunteer-driven causes can apply for Ameriprise Financial’s Community Grants to support programs in areas like hunger relief, shelter, adult self-sufficiency, and arts access. Delaware organizations working on rare disease support alongside these priorities may be eligible if they meet location and documentation requirements.
Ameriprise Financial
O'Reilly Automotive Foundation Grants for Delaware Health
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations improving health, economic stability, or social services in Delaware communities where O’Reilly Auto Parts operates can seek project, operating, or capital support. O'Reilly Automotive Foundation funds programs for underserved people, including health and social services, workforce development, poverty and hunger relief, and disaster response, which may benefit some rare disease–focused initiatives.
O'Reilly Automotive Foundation Inc
Chick Fil A Foundation Grants for Youth
Applications due May 1, 2027
Nonprofit 501(c)(3) organizations with programs for underserved youth, families, food insecurity, or environmental stewardship in Delaware and beyond can seek funding to expand community impact. Chick Fil A Foundation’s True Inspiration Awards offer US $30,000 - US $350,000 for initiatives like youth education, housing support, hunger relief, and related environmental projects, which may benefit rare disease-affected communities.
Chick Fil A Foundation Inc
Community Partnership Funding for Nonprofits from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations in Delaware with strong, replicable community partnerships addressing significant social issues may be eligible for national recognition and support through the Community Partnership Award. Focused on collaborative impact, Mutual of America Foundation honors U.S. nonprofits whose cross-sector partnerships measurably improve lives and can serve as models for other communities, including those tackling rare or respiratory diseases.
Mutual Of America Foundation