Best Addiction and Substance Abuse Grants in District of Columbia

Nonprofit 501(c)(3) organizations in the District of Columbia that support children, youth services, education, or health and human services can seek program funding that demonstrates clear community need and measurable outcomes. Focused on child- and family-serving work, the Costco Foundation looks for collaborative projects with broad financial support and well-documented budgets that may also benefit those affected by addiction or substance use disorders.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

Nonprofit 501(c)(3) organizations supporting youth health, education, development, or welfare can apply for grants up to US $15,000 from the Dan Paul Foundation, including those in the District of Columbia. Programs may include child advocacy, homelessness and poverty services, refugee enrichment, environmental education, or related workshops, conferences, and scholarships for young people.

Early-stage, impact-first nonprofits and mission-driven startups in the District of Columbia tackling urgent social or environmental problems can apply for Draper Richards Kaplan Foundation support, with awards up to US $300,000. Organizations addressing addiction, substance use disorders, or related health and economic mobility challenges may receive multi-year capital plus intensive capacity-building and community support to scale proven solutions.

Focused on tech-enabled social impact, Cisco Systems Foundation invites District of Columbia nonprofits and NGOs to propose innovative programs in crisis response, education access, or economic empowerment. Organizations serving predominantly economically underserved communities, using technology to expand reach and efficiency, may receive up to US $100,000 through year-round Global Impact Cash Grants.

Educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies in the District of Columbia can seek funding for safety, education, and community development initiatives. State Farm Companies Foundation supports projects like disaster preparedness, home and auto safety, financial literacy, job training, and neighborhood revitalization that create long-term, sustainable community impact.

Nonprofit cultural institutions in the U.S. with audited expenses over $2 million can seek more than US $100,000 for arts and science programs, capital projects, or limited general support. William Randolph Hearst Foundation prioritizes large, established organizations engaging youth, developing artistic talent, or offering STEAM-focused education, which may benefit District of Columbia communities.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Nonprofit organizations providing health, education, or community services, including in the District of Columbia, can seek funding for programs such as healthcare access, food pantries, STEM education, and wellness initiatives. Labcorp Charitable Foundation supports U.S.-based 501(c)(3) and equivalent charities whose work may include addiction and substance use prevention, treatment, or related community health services.

Organizations serving children and youth in education, health, or family economic stability in the District of Columbia and other eligible areas can apply for Michael & Susan Dell Foundation grants; awards more than US $50,000 for project support or scaling. Programs addressing addiction, substance use, or related mental health among urban low-income youth may be eligible.

Accredited charities in the District of Columbia working on humanitarian, social, educational, environmental, or arts programs can apply for Roche’s Corporate Donations and Philanthropy support. Projects that promote sustainable development and community well-being, including services that may support people affected by addiction or substance use disorders, may be eligible within Roche’s global focus areas.

Nonprofit and humanitarian organizations in the District of Columbia working on health care access, disease prevention, or broader human and social services can apply for Semnani Family Foundation support. This global funder prioritizes marginalized communities, including in the U.S., and may support addiction-related or co-occurring health and social service programs serving vulnerable populations.

District of Columbia nonprofits working on community development, housing, basic needs, or related services can access funding through Bank of America Charitable Foundation’s sponsorship program. Support may benefit organizations whose addiction and substance use programs intersect with housing, workforce development, hunger, arts, environmental initiatives, or diversity and inclusion in low- and moderate-income communities.

Cowles Charitable Trust provides District of Columbia health, education, social justice, and arts nonprofits with support for programs or general operating costs. U.S.-based 501(c)(3) organizations can request up to US $10,000, and addiction or substance use initiatives may be eligible when they align with the trust’s priorities in health, medical, or climate research.

Nonprofit 501(c)(3) organizations and aligned for-profits seeking to tell impactful stories about preservation, education, or wellness work in the District of Columbia can use this grant to fund storytelling projects. The Jesse W Couch Charitable Foundation offers more than US $50,000, and wildlife conservation nonprofits may be especially eligible for unsolicited applications.

Southern U.S. 501(c)(3) organizations active for over three years and serving people in hardship can apply for Robinson Foundation’s single-year grants to support programs in poverty relief, children and families, education, health, disaster relief, and related services. District of Columbia nonprofits addressing addiction or substance use within these priorities may be eligible.

Nonprofit 501(c)(3) organizations providing community services in the District of Columbia can receive philanthropic grants or event sponsorships to support their programs and fundraising efforts. Insperity provides District of Columbia community organizations with financial support when they engage Insperity employees, are Insperity clients, or serve communities where its employees live and work.

Nonprofit 501(c)(3) organizations in the District of Columbia can apply for the Dudley T Dougherty Foundation’s grants to support community services, environmental conservation, and peacebuilding initiatives. Programs that address addiction, substance use disorders, or related community impacts within these broader areas may be eligible for support.

Nonprofit 501(c)(3) organizations near TJX locations in the District of Columbia can seek funding for basic needs, youth enrichment, workforce readiness, and safety from domestic violence. The TJX Foundation supports programs helping vulnerable children and families access food, clothing, shelter, out-of-school opportunities, and training that build better futures; addiction-related services may be eligible when aligned.

Nonprofit 501(c)(3) organizations, public schools, and libraries in the District of Columbia can seek $5,000 - $10,000 in unrestricted operating or program support for environmental, human services, or related work. Focused on these areas, Lawrence Foundation invites applicants whose addiction and substance use programs fall within its stated funding priorities.

Nonprofit organizations in the District of Columbia offering community-based programs can apply for the Max and Victoria Dreyfus Foundation’s US $1,000 - US $20,000 grants to support museums, arts, education, health facilities, environmental efforts, and social services. Addiction and substance use programs that fit these categories may be eligible if a relatively small award would make a large impact.

Nonprofit 501(c)(3) organizations in the District of Columbia working on hunger relief, shelter, or adult self-sufficiency programs can seek support for basic needs and community vitality initiatives. Ameriprise Financial provides funding nationwide, prioritizing groups with active Ameriprise volunteer engagement and those serving U.S. communities, including key employee center cities.

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

Nonprofit 501(c)(3) organizations providing community services such as economic stability, workforce development, health and social services, or disaster relief in the District of Columbia may be eligible for project, operating, or capital support. Grants from O'Reilly Automotive Foundation help U.S.-based community-focused nonprofits, including those serving people affected by addiction or related health and social challenges.

Nonprofit 501(c)(3) organizations in the District of Columbia working with underserved youth and families can apply for Chick Fil A Foundation’s True Inspiration Awards, with grants of US $30,000 - US $350,000 for community, housing, food insecurity, education, and environmental programs. Youth-serving addiction and substance use initiatives may be eligible if they fit these categories.

U.S. nonprofit organizations leading strong, replicable community partnerships can receive national recognition and funding support through the Mutual of America Foundation’s Community Partnership Award. With a mission to honor exemplary collaborations, the foundation provides awards to six organizations whose cross-sector partnerships measurably improve communities, which may include initiatives addressing addiction and substance use in the District of Columbia.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.