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Best District of Columbia Grants for Nonprofits

Find the perfect District of Columbia grants for nonprofits on Instrumentl. 9,000+ District of Columbia grants for nonprofits in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,337 Results based on applied filters

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders (2026-06-26)

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

Hematological Systems

Pediatric Hidradenitis Suppurativa Challenge Grant

Pediatric Dermatology Research Alliance Inc
Private
United States
Up to US $50,000

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

  • Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
  • Early disease and factors involved in severe disease development
  • Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
  • Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

  • Up to $50,000 to support one year of research
  • One award anticipated for this funding cycle
Children’s Health & Pediatrics

The Alpha Omega Alpha/Pharos Poetry Award

Alpha Omega Alpha Honor Medical Society
Private
United States
US $1,500

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Poetry Education - Higher Education

Native Entities Grant Program

DOC NIST ERA
Federal Government
United States
US $500,000 - US $2,500,000
The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.
Native American Services Technology Access & Digital Literacy Indigenous Services

DoW Bone Marrow Failure, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.
Skeletal Diseases Myeloma

DoW Bone Marrow Failure, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.
Skeletal Diseases Myeloma

DoW Rare Cancers Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $490,000
The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.
Cancer / Oncology

DoW Rare Cancers Resource and Community Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,120,000
The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.
Cancer / Oncology

DoW Joint Warfighter Medical, Military Medical Research and Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $1,400,000 - US $3,000,000
The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.
Military Operations

DoW Bone Marrow Failure, Resource Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.
Skeletal Diseases Myeloma

DoW Parkinson’s, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.
Parkinson’s Disease

Fiscal Year (FY) 2027 Department of the Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
United States
US $450,000 - US $525,000
The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.
Engineering Education - Higher Education Science +1 more

DoW Parkinson’s, Early Investigator Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,000,000
The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.
Parkinson’s Disease

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Child Protection Compact Annual Program Statement (362907)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $5,000,000 - US $10,000,000
The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.
Child Welfare Services Human Trafficking

TIP Office International Programs to Combat Human Trafficking Annual Program Statement (362906)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $10,000,000
The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.
Human Trafficking

DOW Combat Readiness – Medical Research Program Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention Post-Traumatic Stress Disorder

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

Childhood Asthma in Urban Settings Clinical Research Network

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.
Respiratory Diseases & Systems Asthma

Karen C. and A. Wells Ridenour Nursing Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

Community Foundation of Washington County Maryland

We are one of more than 750 similar tax-exempt public charities throughout the United States that work to make their community a better place to live. We are a local organization staffed by residents of the community and led by a board of trustees who have an in-depth knowledge of the issues that shape our County.

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

About Our Scholarships

The Community Foundation of Washington County, MD offers more than 100 scholarships for graduating high school students and non-traditional students in continuing education.

Karen C. and A. Wells Ridenour Nursing Scholarship Fund

This scholarship supports a Washington County resident of any age, race, or gender that’s accepted to an accredited four-year nursing program with the intention of completing a Bachelor of Science in Nursing.

Education - Higher Education Nursing

Jim Barker Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
More than US $1,000

Community Foundation Serving Western Virginia

Our Community Foundation was established in Roanoke in 1988. With our growth, we expanded into the Martinsville/Henry County area in 2005. Today, we administer many hundreds of named endowment funds ranging in size from a minimum of $10,000 to millions of dollars. To date, donors have also committed very significant resources to the Foundation through future estate gifts.

Our Mission:Enabling people who love their community to easily give back.

Scholarships

Community Foundation Serving Western Virginia, the region’s community foundation, administers a variety of scholarships to reward and assist capable and deserving students based on the criteria established by the fund donors.

Jim Barker Scholarship Fund

Fund provides higher educational scholarship assistance to deserving students.

Education - Higher Education Vocational & Trade Education

Joycelyn “Fudgie” Lee Farrelly Music Education Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
US $1,000

Community Foundation Serving Western Virginia

Our Community Foundation was established in Roanoke in 1988. With our growth, we expanded into the Martinsville/Henry County area in 2005. Today, we administer many hundreds of named endowment funds ranging in size from a minimum of $10,000 to millions of dollars. To date, donors have also committed very significant resources to the Foundation through future estate gifts.

Our Mission:Enabling people who love their community to easily give back.

Scholarships

Community Foundation Serving Western Virginia, the region’s community foundation, administers a variety of scholarships to reward and assist capable and deserving students based on the criteria established by the fund donors.

Joycelyn “Fudgie” Lee Farrelly Music Education Scholarship Fund

Fund provides higher education scholarship assistance to deserving students who intend to pursue a degree in music or music education.

Education - Higher Education Music Music Education

Jerrold E. Potts Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Jerrold E. Potts Scholarship

Jerrold E. Potts was born and raised in Saginaw, living here until his death in 1997. An electrician by trade, he served in the U.S. Army and Army Reserves. Jerry was a longtime member of the International Brotherhood of Electrical Workers Local #557. He was also a member of the Saginaw Lodge #77, F&AM, where he twice served as Worshipful Master.

Jerry was a caring, compassionate person who supported many causes, often anonymously. When establishing the Jerrold E. Potts Scholarship, Jerry indicated that the primary scholarship beneficiaries should be the children and grandchildren of IBEW 557 members because “I started there.” He also wanted the scholarship to “make the difference between going to school and not going to school.”

Education - Higher Education

Judge Gary R. McDonald Memorial Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Judge Gary R. McDonald Memorial Scholarship

January 2004 marked the passing of a true champion of justice and compassion for the men and women of Michigan. Judge Gary R. McDonald, beloved father and friend, served the citizens of Saginaw and the rest of Michigan for over 30 years.

In honor of his esteemed service, the family and colleagues of this respected Michigan leader have created the Judge Gary R. McDonald Memorial Scholarship Fund. Its purpose is to grant students of Saginaw County the financial means to pursue a career in a law-related field so that Judge McDonald’s unrelenting pursuit of justice may continue in his honor.

Awarding this scholarship to those in need serves Judge McDonald’s personal mission of inspiring the hearts and minds of our youth to serve our communities for the good of all.

Education - Higher Education Vocational & Trade Education

Junior League of the Great Lakes Bay Region Scholarship

Saginaw Community Foundation
Private
United States
Unspecified amount

Scholarships

Since awarding our first $500 scholarship in 1987, the Saginaw Community Foundation has awarded college scholarships to area students totaling more than $13.7 million, thanks to our generous donors. Each year, over 500 college-bound or career and technical education students benefit from our scholarship awards.

Our single application process makes it easy to potentially qualify for one or more of our 260+ scholarships.

Junior League of the Great Lakes Bay Region Scholarship

Junior League of the Great Lakes Bay Region is an organization of women committed to promoting volunteerism, developing the potential of women and improving the community through the effective action and leadership of trained volunteers. Its purpose is exclusively educational and charitable. The Junior League of the Great Lakes Bay Region is an organization that welcomes for membership all women regardless of age, race, creed, religion or national origin, who demonstrate an interest in and commitment to volunteerism.

The league has had many fundraising events in its history, always with the purpose of returning monies to the community through varied and needed projects. The Junior League of the Great Lakes Bay Region Scholarship is one of those projects.

Education - Higher Education Vocational & Trade Education

District of Columbia Grants for Nonprofits Highlights

District of Columbia grants for nonprofits provide funding to support community development, education, public health, and arts programs. The following grants help organizations address local challenges and foster positive change across Washington, D.C.


Search Instrumentl's District of Columbia Grants Database


Discover 290 funding opportunities for nonprofits in Washington, D.C., with $64.4M available. Instrumentl supports organizations by offering deadline tracking, refined grant searches, and funder insights to advance impactful programs in the nation's capital.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : District of Columbia Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ District of Columbia grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ District of Columbia grants for nonprofits over $25K in average grant size

100+ District of Columbia grants for nonprofits over $50K in average grant size

55 District of Columbia grants for nonprofits supporting general operating expenses

200+ District of Columbia grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for District of Columbia grants for Nonprofits?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for District of Columbia Grants for Nonprofits?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.
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