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Best District of Columbia Grants for Nonprofits

Find the perfect District of Columbia grants for nonprofits on Instrumentl. 9,000+ District of Columbia grants for nonprofits in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,333 Results based on applied filters

Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,500,000
This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.
Drug Use Disorder Addiction & Substance Use Disorders Pharmacology +1 more

B.W. Bastian Foundation Grant

B.W. Bastian Foundation
Private
United States
US $100 - US $15,000
The B.W. Bastian Foundation Grant supports organizations committed to equality for all Americans, including the LGBTQ+ community. Grants typically range from $100 to $15,000, and applicants must have 501(C)3 tax status. Funding is primarily for projects in the Intermountain West and may include general operating support or specific programs. Organizations should first inquire before applying, especially if requesting more than previous grants. The foundation does not fund individuals or lobbying efforts.
Racial / Ethnic Justice & Rights Social Justice / Human Rights Disability Rights & Justice +5 more

SPRK-ing Interest in Computer Science

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Guam +6 more
Unspecified amount in in-kind support
The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.
Computer Science & Engineering STEM / STEAM Education

Infrastructure Capacity for Biological Research (347679)

National Science Foundation (NSF)
Federal Government
United States
US $25,000 - US $1,200,000
The Infrastructure Capacity for Biological Research Program, supported by the National Science Foundation, aims to enhance research capabilities across various biological disciplines. This program encourages proposals for developing and improving research tools and services in areas such as Cyberinfrastructure and Biological Collections. It also welcomes planning activities to foster collaboration among researchers. Projects must ensure broad accessibility and significant scientific outcomes for the wider research community.
Biology Cyberinfrastructure Marine Biology

Infrastructure Innovation for Biological Research (347680)

National Science Foundation (NSF)
Federal Government
United States
US $300,000 - US $800,000
The Infrastructure Innovation for Biological Research Program by NSF aims to enhance contemporary biology through innovative research tools and methods. It focuses on developing or redesigning infrastructure in bioinformatics, instrumentation, and research methods. Projects should significantly advance biological understanding and be applicable to a wider research community. Proposals should aim at transforming biological research by either creating novel tools or adapting existing ones in meaningful ways, addressing fundamental questions in the biological sciences.
Biology Non-Medical Bioinformatics

FY 2023 Disaster Supplemental

US Department of Commerce: Economic Development Administration (EDA)
Federal Government
United States
Up to US $30,000,000
The FY 2023 Disaster Supplemental grant aims to support communities affected by major disasters, such as Hurricanes Ian and Fiona, by funding both construction and non-construction projects. This initiative focuses on long-term economic recovery strategies to address the challenges faced in areas with federal disaster declarations. Additionally, the Economic Development Administration has launched the Economic Development Grants Experience (EDGE) platform to enhance the efficiency and transparency of the grant management process.
Economic Services & Development Community Development & Revitalization Disaster Relief / Humanitarian Aid +1 more

ABC-CLIO Leadership Grant

American Library Association (ALA)
Association/Society
United States
Up to US $1,750
The ABC-CLIO Leadership Grant supports AASL Chapters in developing leadership programs for school library associations at various levels. This grant encourages initiatives that engage new members, train current leaders, and foster collaboration among organizations. Successful applications clearly define program objectives, participant groups, and include well-structured budgets and evaluation plans. The grant aims to promote innovative leadership approaches that can be replicated by other chapters, enhancing the overall effectiveness of school libraries.
Library Services

Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,375,000
The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.
Cancer / Oncology Nanomaterials & Nanotechnology

Pioneering Aerospace Capabilities, Engineering and Research (PACER)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
United States
Unspecified amount
The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program is a 20-year Broad Agency Announcement (BAA) by the US Air Force aimed at advancing innovative aerospace technologies. This initiative encourages white papers and proposals for research and development to enhance technology readiness levels. It is designed to provide the warfighter with a decisive advantage through transformative technology solutions. Multiple awards are anticipated, allowing for a range of project durations and funding values.
Aerospace Engineering

Wild Animal Initiative: Seed Grants

Wild Animal Initiative
Private
Afghanistan, Albania +189 more
Up to US $30,000
The Wild Animal Initiative offers Seed Grants to support innovative projects in wild animal welfare research. These grants aim to facilitate early-career researchers and established scientists in testing new techniques and approaches that incorporate welfare assessments into ecological studies. The program emphasizes cost-effective solutions, focusing on improving the welfare of wild animals. Successful proposals will explore diverse themes such as wild fish welfare and near-term welfare interventions to address urgent animal welfare challenges.
Wildlife Health Ichthyology (Fish)

Arctic Research Opportunities (349724)

National Science Foundation (NSF)
Federal Government
Canada, Greenland +1 more
Up to US $330,000
The National Science Foundation (NSF) seeks proposals for Arctic research to enhance understanding of the rapidly changing Arctic environment and its social systems. This initiative encourages innovative research that connects the Arctic region with lower latitudes, aiming to improve projections of future changes. Collaborations with federal and international partners are encouraged for co-reviewing proposals. Proposals that extend beyond the Arctic must clearly articulate their relevance to Arctic knowledge advancement.
Oceanography Hydrology Environment +7 more

Leonard-Litz Foundation: LGBTQ+ Community Grants

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard Litz Foundation supports LGBTQ+ organizations through grants that promote health, wellness, crisis intervention, racial justice, advocacy, and social assistance. Priority is given to organizations in the northeast U.S. and those serving communities of color and transgender individuals. Applications that clearly link funding requests to specific needs will receive stronger consideration. The foundation aims to foster a supportive environment for the LGBTQ+ community to thrive.
LGBTQIA+ Services Sexuality & LGBTQIA+ Rights

Leonard-Litz Foundation: LGBTQ+ Advocacy Fund Grant

Leonard Litz Foundation
Private
United States
Unspecified amount
The Leonard-Litz Foundation's LGBTQ+ Advocacy Fund Grant aims to empower LGBTQ+ individuals by funding organizations that advocate for their rights and well-being. With a focus on health, wellness, and racial justice, the fund supports projects that require significant investment for impactful change. Prioritizing partnerships that serve vulnerable communities, including people of color and transgender individuals, this grant fosters equality and addresses systemic inequalities faced by LGBTQ+ people, especially in the northeast U.S.
Sexuality & LGBTQIA+ Rights LGBTQIA+ Services

We Raise Foundation: Emerging Leader Grant

We Raise Foundation
Private
United States
US $15,000
The We Raise Foundation's Emerging Leader Grant supports individuals aged 20-35 at Christian organizations developing innovative programs addressing poverty, violence, and inequality. With a total of $15,000 over two years, the grant allocates $10,000 for program support and $5,000 for leadership development, including coaching and conferences. This initiative aims to foster impactful leaders who inspire, communicate effectively, and engage deeply with their communities, ultimately creating lasting change.
Civic Leadership Development Christianity Poverty Alleviation & Services +2 more

Middle School Music Grant

Peter R Marsh Foundation
Private
United States
US $1,250
The Middle School Music Grant, offered by the Peter R Marsh Foundation, aims to enrich the musical education of public middle school music teachers across the U.S. By facilitating performances at senior facilities, the grant fosters emotional connections between students and seniors, while providing essential classroom equipment. Funds cover music supplies, instruments, and transportation, ensuring students have the resources to thrive musically and socially. This initiative not only enhances music education but also promotes community engagement and empathy.
Music Education

Just Tech Fellowship

Social Science Research Council
Private
United States
Approximately US $200,000
The Just Tech Fellowship, supported by the Social Science Research Council, aims to empower diverse researchers and practitioners to address injustices arising from new technologies. With a two-year award of $100,000 annually, this fellowship fosters collaboration and community engagement, promoting equitable tech futures. It focuses on the intersection of technology and social justice, encouraging insights from historically marginalized groups to inform structural change and create a more just society.
Technology Access & Digital Literacy Emerging Technology Development

Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The US Department of Health & Human Services, through the NIH, invites applications for innovative approaches to implement SBIRT/P for addressing alcohol, tobacco, and other drug use in adults facing health disparities. This funding opportunity encourages research that tests screening, brief interventions, and referrals for treatment or prevention services. Applications are due on specified deadlines from February 2024 through March 2027, fostering collaboration with healthcare and community partners to enhance public health outcomes.
Health Disparities & Social Determinants of Health Drug Use Disorder Alcoholism +2 more

Catalyze Challenge Grant

Catalyze
Association/Society
United States
Up to US $300,000
The Catalyze Challenge Grant, managed by Catalyze, is an opportunity for organizations to receive funding for innovative solutions that enhance career-connected learning for youth aged 11-22. With over $4 million available in Round 5, finalists can secure up to $300,000 to implement their ideas. The grant seeks proposals that empower underserved learners through hands-on experiences and meaningful employer partnerships, ultimately impacting over 65,000 young people across the U.S.
Career / College Preparation Educational Access & Equity Academic Success & Enrichment +3 more

Coors Light Líderes Grant Program

Molson Coors Beverage Co
Corporate
Puerto Rico, United States
US $10,000
The Coors Light Líderes Grant Program honors exceptional Latino leaders across the U.S. and Puerto Rico, awarding five individuals with a $10,000 grant each for their nonprofit organizations. This initiative, active for 17 years, aims to empower emerging leaders who demonstrate significant community impact through innovative programs. Eligible nominees must be between 21-39 years old, associated with a 501(c)(3) nonprofit, and committed to fostering positive change in their communities.
Hispanic and Latino Services Hispanic and Latino Culture & Heritage

AHRQ Improving Diagnostic Safety in Ambulatory Care: Strategies and Interventions (R18)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The AHRQ Improving Diagnostic Safety in Ambulatory Care (R18) program invites proposals aimed at enhancing diagnostic safety in ambulatory settings. This initiative supports the development, testing, and evaluation of strategies and interventions that address diagnostic challenges in healthcare. The goal is to improve patient safety and quality of care through innovative solutions tailored to the diverse needs of ambulatory care environments.
Health Care Access & Delivery Home Health Care Telemedicine & Telehealth

AHRQ Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors (R01) (349962)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The AHRQ is inviting proposals for research focused on improving diagnostic safety in ambulatory care settings. This funding opportunity aims to understand the incidence and contributing factors of diagnostic errors that occur across various ambulatory care services. Proposals should address the complexities of diagnostic safety to enhance patient care and outcomes.
Patient Care & Services Home Health Care Health Care Access & Delivery +1 more

Mockingbird- Nonprofit Incubator Grant Program

Mockingbird Incubator
Private
United States
Up to US $3,000
The Mockingbird Nonprofit Incubator Grant Program supports emerging nonprofit founders in creating sustainable growth and impact. The program includes eight live workshops on nonprofit management, fundraising, and access to resources from Givebutter. Selected organizations receive scholarships and the chance to apply for $4,000 in grant funds. Eligibility is limited to 501c3 nonprofits or those under fiscal sponsorship with budgets under $500,000, fostering a community of committed leaders ready to make a difference.
All fields of work Community Services Social Justice / Human Rights +1 more

Teagle Foundation: Knowledge for Freedom

The Teagle Foundation Incorporated
Private
United States
US $10,000 - US $300,000
The Teagle Foundation's Knowledge for Freedom initiative aims to empower underserved high school students through transformative experiences in the humanities. Grants ranging from $100,000 to $300,000 over 36 months support programs that foster civic responsibility and personal purpose. Colleges can also apply for planning grants of $10,000 to $25,000 to develop tailored programs. The initiative emphasizes intensive summer seminars led by faculty, with continued support for college applications and civic engagement.
Civic Engagement & Education Civic Leadership Development Governance & Democracy

Find Your Light Grant

Find Your Light Foundation
Private
United States
US $5,000 - US $15,000
The Find Your Light Foundation is committed to providing every child with access to quality arts education. By focusing on direct support for exceptional programs, along with education, advocacy, and outreach, they aim to highlight the importance of arts in youth development. Grants are awarded to arts education initiatives in low-income areas across North America, typically ranging from $5,000 to $15,000, with awards issued in the Summer and Winter each year.
Art Education

Dog Enrichment Grant

Petfinder Foundation
Private
Canada, Mexico +1 more
Up to US $4,000
The Dog Enrichment Grant, offered by the Petfinder Foundation, aims to enhance the quality of life for dogs awaiting adoption through enrichment activities and items. Grants are available for play yard renovations (up to $3,000) and interactive items (up to $1,000). Applications are accepted monthly until funds are depleted, and the window closes on November 1. Eligible expenses must be utilized within three months, and reimbursement requests will not be accepted.
Animal Welfare - Domestic Animals & Pets

Vadon Foundation Grant

Vadon Foundation
Private
Canada, United States
Unspecified amount
The Vadon Foundation Grant supports innovative, community-based initiatives aimed at sustaining healthy indigenous nations. By empowering visionary changemakers, the foundation addresses multi-generational challenges through focused programming in areas like language revitalization, community leadership, and addressing crises such as food insecurity. The foundation seeks to foster self-determination and sustainability within native communities, ensuring that future generations can thrive culturally and socially.
Indigenous Sovereignty & Rights Native American Culture & Heritage Native American Services

.ORG Impact Awards

Public Interest Registry
Private
Afghanistan, Albania +189 more
Up to US $50,000
The .ORG Impact Awards, organized by the Public Interest Registry, honor individuals and organizations connected to .ORG domains for their impactful contributions in areas such as health, education, diversity, and environmental stewardship. Participants can receive up to $50,000 for their chosen non-profit and gain visibility through various promotional platforms. This initiative not only recognizes excellence but also fosters community support and encourages innovative solutions to pressing societal issues.
Educational Access & Equity Mental Health & Psychiatric Diseases Health Care Access & Delivery +7 more

District of Columbia Grants for Nonprofits Highlights

District of Columbia grants for nonprofits provide funding to support community development, education, public health, and arts programs. The following grants help organizations address local challenges and foster positive change across Washington, D.C.


Search Instrumentl's District of Columbia Grants Database


Discover 290 funding opportunities for nonprofits in Washington, D.C., with $64.4M available. Instrumentl supports organizations by offering deadline tracking, refined grant searches, and funder insights to advance impactful programs in the nation's capital.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : District of Columbia Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ District of Columbia grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ District of Columbia grants for nonprofits over $25K in average grant size

100+ District of Columbia grants for nonprofits over $50K in average grant size

55 District of Columbia grants for nonprofits supporting general operating expenses

200+ District of Columbia grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for District of Columbia grants for Nonprofits?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for District of Columbia Grants for Nonprofits?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.
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