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Best District of Columbia Grants for Nonprofits

Find the perfect District of Columbia grants for nonprofits on Instrumentl. 9,000+ District of Columbia grants for nonprofits in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,333 Results based on applied filters

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (357658)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.
Science Biology Health & Medicine +2 more

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Outdoor Recreation Legacy Partnership Program (ORLP) Recurring Notice 5 Year

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $15,000,000
The Outdoor Recreation Legacy Partnership Program (ORLP) is a competitive grant initiative by the National Park Service, aimed at enhancing parks and recreational opportunities in urban, underserved communities. This program supports the acquisition, development, and renovation of outdoor recreation areas through federal funding, addressing the needs of community organizations, local governments, and recognized tribes. Applications are accepted twice a year, before June 1 and November 1.
Parks & Public Spaces Outdoor Recreation Outdoor Equity

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 1

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 2

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.
Health & Medicine Medical Ethics Artificial Intelligence (AI)

Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Risk and Protective Factors of Family Health initiative invites research proposals to explore family health and resilience, addressing health disparities in minority communities. Key submission deadlines are set for various dates from February 2025 to February 2027. This program is supported by the National Institutes of Health, highlighting the importance of family well-being as a critical area for advancing health equity. Proposals should focus on interventions that improve family health outcomes.
Family Services Minority Services Health Disparities & Social Determinants of Health

ASTS: Veloxis Fellowship in Transplantation Grant

American Society Of Transplant Surgeons
Private
North America
US $85,000
The ASTS: Veloxis Fellowship in Transplantation Grant offers $42,500 per year for two years to support clinical training in solid organ transplantation. This grant is aimed at current transplant surgery trainees who have completed their surgical residency and are committed to the field. Awardees must attend the ASTS Award Ceremony and complete their fellowship at the same institution for the duration of the award, ensuring a focused and comprehensive training experience.
Surgery Organ And Tissue Banks

Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,900,000
The National Cancer Institute (NCI) invites applications for the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) program. This funding opportunity focuses on advanced pre-clinical research aimed at developing nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards will support the maturation of innovative nanomedicines using nanoparticles and nano-devices, enhancing cancer treatment efficacy. Successful projects will progress towards further NCI translational programs, such as the NExT initiative.
Cancer / Oncology Nanomaterials & Nanotechnology

Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional) (357744)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
This funding opportunity supports exceptionally promising Early Stage Investigators in genomics, encouraging innovative research across various fields such as genomic sciences and medicine. Applicants must submit their proposals by 5:00 PM local time of their organization. The initiative, led by the US Dept. of Health & Human Services through the NIH, aims to foster long-term career development in genomic research while addressing its ethical, legal, and social implications.
Genetics & Genomics Medical Ethics

Dean John A. Knauss Marine Policy Fellowship

Woods Hole Oceanographic Institution (WHOI)
Private
American Samoa, Guam +4 more
Unspecified amount
The Dean John A. Knauss Marine Policy Fellowship offers a unique opportunity for early career professionals to engage in marine and Great Lakes science and policy within the U.S. government. This one-year, paid fellowship encourages graduate students from accredited programs to explore impactful coastal resource issues. Interested applicants should connect with their local Sea Grant program or the National Sea Grant Office for guidance, especially if they are from Massachusetts, to ensure a competitive application.
Marine Biology Marine / Ocean Conservation Environmental Policy +2 more

The Transformational Partnerships Fund: Catalytic Grants

ECMC Foundation
Private
United States
Up to US $100,000
The Transformational Partnerships Fund offers catalytic grants of up to $100,000 for colleges and universities to explore innovative partnerships. These grants aim to enhance student success by facilitating collaborations that can significantly change institutional operations. Priority is given to partnerships involving diverse student populations and those expected to yield better outcomes. This opportunity supports institutions in assessing transformative possibilities, making it an essential resource for educational advancement.
Education System Policy & Reform College Success / Persistence

The Transformational Partnerships Fund: Seed Grants

ECMC Foundation
Private
United States
Up to US $10,000
The Transformational Partnerships Fund offers Seed Grants of up to $10,000 to colleges and universities seeking to explore partnerships that can enhance their operations. These grants support events aimed at fostering collaboration among leadership and stakeholders, paving the way for transformative initiatives. Applications are reviewed on a rolling basis, encouraging institutions to engage actively in crafting sustainable solutions centered on student success.
Education System Policy & Reform College Success / Persistence

CFWM: Scholarship Program

Community Foundation of Western Massachusetts
Private
United States
Up to US $3,000
The Community Foundation of Western Massachusetts offers a Scholarship Program aimed at assisting students in Franklin, Hampden, and Hampshire counties with their college education expenses. Annually, they provide over 1,000 scholarships, totaling approximately $1.4 million. Eligible applicants include undergraduate and graduate students enrolled in accredited institutions across the U.S. Scholarships can help cover tuition, fees, and living costs, with awards up to $3,000 available for one academic year.
All fields of work

Updated National Dislocated Worker Grant Program Guidance and Application Information

US Department of Labor: Employment and Training Administration (ETA)
Federal Government
United States
US $150,000 - US $10,000,000
The Updated National Dislocated Worker Grant Program Guidance informs workforce development systems about the policies and priorities for using National Dislocated Worker Grant funds. This guidance outlines grant types, funding approaches, performance periods, cost limitations, and application requirements. It emphasizes the critical role of DWGs in supporting economic recovery, community resilience, and equitable workforce development, ensuring that these funds effectively contribute to creating good jobs and enhancing local economies.
Employment Services Workers’ Rights Disaster Relief / Humanitarian Aid

ALF: Pilot Research Awards

American Liver Foundation
Private
United States
US $50,000
The ALF: Pilot Research Awards offer funding of $50,000 for one year to early career investigators focusing on innovative research in rare liver diseases. These awards aim to support junior faculty during the pilot phase of their projects, encouraging high-risk, high-reward ideas. Proposals should present clear, testable hypotheses without the need for extensive preliminary data, ultimately aiming to generate key findings that can lead to larger NIH grants.
Liver Disease

Bettye Smith Brown Memorial Scholarship Fund

Community Foundation For Mississippi
Private
United States
US $10,000
The Bettye Smith Brown Memorial Scholarship Fund honors a dedicated advocate for education, offering two $10,000 scholarships annually to high school seniors in Warren County, MS. Eligible applicants must be U.S. citizens with strong academic records and demonstrate financial need. This scholarship celebrates the legacy of Ms. Brown, who inspired many to pursue their educational dreams, ensuring her commitment to academic excellence continues to impact future generations.
Career / College Preparation Academic Scholarship Programs

Congressional Science Fellowship

Crop Science Society of America (CSSA)
Association/Society
United States
Unspecified amount
The Congressional Science Fellowship Program offers a unique opportunity for Ph.D. holders to work at the intersection of science and government in Washington D.C. This prestigious fellowship, sponsored by ASA, CSSA, and SSSA, allows participants to apply their expertise as special assistants to Congress members. The fellowship begins in September 2025 and concludes in August 2026, providing an annual stipend and relocation expenses. Ideal for early to mid-career scientists, it encourages the use of scientific knowledge in public policy.
Public Policy Education - Higher Education Political Science

Lindsay Lloyd North Korea Freedom Scholarship

Communities Foundation of Texas
Private
American Samoa, Guam +4 more
Up to US $10,000

Lindsay Lloyd North Korea Freedom Scholarship

The Lindsay Lloyd North Korea Freedom Scholarship (supported by the George W. Bush Foundation) provides one or more annual scholarships for up to $10,000 to lawful permanent residents of the United States, U.S. citizens or refugees who were born in North Korea pursuing an educational program in the United States or its possessions. North Korean-born individuals pursuing a degree in accredited colleges and universities in the United States with South Korean citizenship are eligible to apply.

This scholarship may be renewed on an annual basis by completing the scholarship application in full. Renewal applications will be reviewed alongside first-time applicants.

Immigrant Services Refugee Services

Remote Biomarker Measurements in Microphysiological Systems Grant

Translational Research Institute for Space Health
Association/Society
United States
Unspecified amount
The Remote Biomarker Measurements in Microphysiological Systems Grant seeks innovative proposals to enhance remote biomarker analysis technologies for microphysiological systems, crucial for deep space missions. It prioritizes non-invasive, adaptable methods that allow for continuous monitoring of biomarkers without sample return. This initiative aims to advance personalized healthcare and biological research, addressing astronaut health in challenging environments. Eligible entities include U.S. institutions and collaborations with foreign entities under specific conditions.
Astrobiology Space Science

Lady Suzanna P. Tweed Scholarship

Coral Gables Community Foundation
Private
United States
US $500 - US $1,000
The Lady Suzanna P. Tweed Scholarship, administered by the Coral Gables Community Foundation, honors Lady Tweed's legacy of supporting education and volunteerism. Aimed at students from Coral Gables Senior High, it requires excellence in academics and community involvement. Awards are based on financial need and can be one-year or renewable. Over $2.9 million in scholarships have been granted in the past decade, helping deserving students further their education at various institutions.
Academic Scholarship Programs Youth Development & Leadership College Success / Persistence

Kerdyk Family Trust Music Scholarship

Coral Gables Community Foundation
Private
United States
Up to US $2,000
The Kerdyk Family Trust Music Scholarship, administered by the Coral Gables Community Foundation, honors students with a passion for music. Established in memory of Commissioner William H. Kerdyk, Sr., this annual scholarship is awarded to graduating seniors who demonstrate musical interest and academic success. Key eligibility factors include residing in Coral Gables and planning to pursue music studies in college. The scholarship supports students aiming for a career in music, fostering future talent in the arts.
Academic Scholarship Programs Music Education Career / College Preparation

Jeannett Slesnick Community Spirit Scholarship

Coral Gables Community Foundation
Private
Alachua County, Florida, Charlottesville City, Virginia +3 more
US $500 - US $2,500
The Jeannett Slesnick Community Spirit Scholarship offers up to four years of college tuition assistance for graduating seniors from Coral Gables High School, Miami Senior High School, or ISPA. Applicants should demonstrate an interest in communications, journalism, leadership, or historic preservation, and must maintain a 3.0 GPA. Established in 2022 by Jeannett and Don Slesnick, this scholarship honors Jeannett's commitment to community service and education, supporting local high school graduates in their academic pursuits.
Civic Engagement & Education Academic Scholarship Programs College Success / Persistence +2 more

ANR Foundation - Postdoctoral Physician Scientist Fellowship

Arthritis National Research Foundation
Private
United States
Up to US $50,000
The ANR Foundation Postdoctoral Fellowship offers financial support to researchers focusing on arthritis and related autoimmune diseases. This initiative aims to cultivate future leaders in the field by providing fellowships that foster innovative research and exceptional training opportunities. Open to various research areas, including osteoarthritis and lupus, the fellowship seeks to empower physicians to advance their work and make impactful contributions to understanding these conditions.
Immune System Diseases Arthritis Musculoskeletal Diseases +1 more

The Nature Awards Inspiring Women in Science: Scientific Achievement

Springer Nature Limited
Corporate
Afghanistan, Algeria +95 more
Up to US $50,000
The Nature Awards for Inspiring Women in Science celebrate outstanding contributions by women in STEM fields. These awards recognize early-career female researchers who demonstrate exceptional achievements, face challenges, and inspire the next generation through outreach. Winners receive prizes totaling $50,000, mentorship opportunities, and invitations to prestigious ceremonies. This initiative promotes inclusivity and aims to enhance the representation of women in science, thereby supporting a diverse and equitable scientific community.
Engineering Mathematics Science +2 more

Nature Awards for Inspiring Women in Science: Science Outreach Category

Springer Nature Limited
Corporate
Afghanistan, Algeria +95 more
Up to US $50,000
The Nature Awards for Inspiring Women in Science, particularly in the Science Outreach category, honors initiatives that empower girls and young women in STEM fields. With a focus on engagement and retention, the awards aim to celebrate projects that encourage participation in natural sciences, technology, engineering, mathematics, and medicine. Winners will receive significant cash prizes and opportunities for mentorship, creating pathways for future generations of women in science.
Engineering Mathematics Science +2 more

URAF Conference Funding

Harvard University
Private
Countries
US $500 - US $750
The URAF Conference Funding program at Harvard University provides support for undergraduate students presenting original research at academic conferences. With awards up to $500 for domestic conferences and $750 for international presentations, students must be enrolled and in good standing. The program encourages applications year-round, allowing for different iterations of the same presentation. However, funding cannot be applied retroactively, and group applications are not permitted.
Academic Success & Enrichment Education - Higher Education

District of Columbia Grants for Nonprofits Highlights

District of Columbia grants for nonprofits provide funding to support community development, education, public health, and arts programs. The following grants help organizations address local challenges and foster positive change across Washington, D.C.


Search Instrumentl's District of Columbia Grants Database


Discover 290 funding opportunities for nonprofits in Washington, D.C., with $64.4M available. Instrumentl supports organizations by offering deadline tracking, refined grant searches, and funder insights to advance impactful programs in the nation's capital.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : District of Columbia Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ District of Columbia grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ District of Columbia grants for nonprofits over $25K in average grant size

100+ District of Columbia grants for nonprofits over $50K in average grant size

55 District of Columbia grants for nonprofits supporting general operating expenses

200+ District of Columbia grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for District of Columbia grants for Nonprofits?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for District of Columbia Grants for Nonprofits?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.
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