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Best District of Columbia Grants for Nonprofits

Find the perfect District of Columbia grants for nonprofits on Instrumentl. 9,000+ District of Columbia grants for nonprofits in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,333 Results based on applied filters

The Truman Scholarship

HARRY S TRUMAN SCHOLARSHIP FOUNDATION DEVELOPMENT FUND
Private
United States
Up to US $30,000
The Truman Scholarship, established by the Truman Foundation, supports college juniors committed to public service. It offers up to $30,000 for graduate studies, alongside mentoring and career development opportunities. Ideal candidates demonstrate leadership, a strong commitment to public service, and the potential for success in graduate school. This prestigious award aims to cultivate future leaders dedicated to making a positive impact in their communities and beyond.
Education - Higher Education Civic Leadership Development Academic Scholarship Programs

PCORI Call for Proposals for HSII Implementation Projects

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,500,000
The PCORI Call for Proposals for HSII Implementation Projects invites innovative approaches to address barriers in healthcare settings. These projects should enhance practice change through active, multi-component strategies and include rigorous evaluations to measure implementation effectiveness. While developing tools to support these strategies is permitted, it should not be the main focus. Successful proposals will demonstrate their potential impact on healthcare outcomes and patient experiences.
Medical Education & Professional Training Cardiovascular Diseases & Systems

Ollie Hinkle Heart Foundation: Technology Grant

Ollie Hinkle Heart Foundation
Private
United States
Unspecified amount
The Ollie Hinkle Heart Foundation's Technology Grant aims to improve pediatric heart care outcomes through innovative collaborations. By focusing on predictive technologies for early recognition, precision for personalized care, and preventive measures for quality of life, the foundation seeks to transform care for heart children and their families. Their mission emphasizes community support, education, and advocacy to ensure no family faces unmet needs alone, creating a legacy of love and courage in the heart community.
Cardiovascular Diseases & Systems Children’s Health & Pediatrics Medical Technology, Devices, and Equipment

Limited Competition PCORI Funding: Implementation Awards -- Cycle 3 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,500,000
The Implementation Awards by PCORI aim to fund projects that translate patient-centered research into real-world practices. With budgets up to $2.5 million for implementation projects lasting up to 48 months, applicants must present a clear plan for broad evidence uptake. Additionally, those proposing implementation projects need an accepted Draft Final Research Report related to their original PCORI-funded research to qualify for funding.
Patient Care & Services

Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
This funding opportunity aims to enhance the development of medical products in rare diseases through innovative natural history studies. By generating high-quality data, the FDA seeks to bridge critical knowledge gaps and eliminate barriers in rare disease research. The initiative focuses on diseases with unmet needs, fostering significant impacts for those affected and facilitating the development of effective therapeutic solutions.
Rare Diseases Manufacturing Engineering Pharmacology +1 more

NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens (360006)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens. Funded by the FDA, this initiative strengthens the National Antimicrobial Resistance Monitoring System established in 1996. By improving detection methods and expanding sampling sites, the program seeks to protect public health and align with NARMS objectives, ultimately combating the growing threat of antibiotic resistance in food commodities.
Drug-Resistant Bacteria Epidemiology & Public Health

Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
American Samoa, Guam +4 more
Up to US $900,000
The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.
Rare Diseases Medical Ethics Human Genome & Genetics

Yéigo Action Grant

First Peoples Fund
Private
United States
Up to US $2,500
The Yéigo Action Grant, provided by the First Peoples Fund, offers financial support ranging from $100 to $2,500 for Native artists and culture bearers facing hardships that affect their creative practices. This grant aims to assist artists with specific professional opportunities, such as workshops or emergencies. By honoring the spirit of encouragement embodied in the Diné word 'yéigo', the grant helps ensure that artists can continue their vital work within their communities.
Art & Culture Indigenous Services Emergency Medical Care & Services +1 more

Rooted Pathways Program

First Peoples Fund
Private
American Samoa, Guam +4 more
Up to US $55,000
The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.
Artist Training & Development Community Culture & Heritage Arts / Culture Access & Participation +2 more

Rotary Works Foundation Grant

Rotary Works Foundation Inc.
Private
La Crosse County, Wisconsin, United States
US $500 - US $5,000
The Rotary Works Foundation Grant supports charitable projects primarily focused on children, youth, and families, emphasizing active Rotarian involvement. Grants range from $500 to $5,000, awarded prior to events. Eligible applicants include 501(c)(3) or 501(c)(1) organizations. Preference is given to projects engaging Rotarians. The application deadline is the 2nd Wednesday of each month, and all grantees must report outcomes post-project.
Youth Services Youth Development & Leadership Youth Involvement in the Arts +2 more

Native Performing Arts Live Production Grant (LPG)

First Peoples Fund
Private
United States
US $30,000
The Native Performing Arts Live Production Grant (LPG) supports Native artists and organizations in staging live performances, fostering cultural expression. With a $30,000 grant for one year, this initiative prioritizes projects that actively engage Native performers, enhancing their artistic skills and community connections. By addressing the unique needs of Native creators, the program aims to empower them with resources, mentorship, and equitable opportunities in the performing arts landscape.
Music Theater Dance +1 more

Native Performing Arts Fellowship (NPA) Fellowship

First Peoples Fund
Private
United States
Up to US $10,000
The Native Performing Arts Fellowship (NPA) supports Native artists in enhancing their craft through grants of up to $10,000. This fellowship prioritizes personal artistic development over project-based funding, encouraging applicants to focus on growth through classes, workshops, and professional mentorship. Eligible candidates must be U.S.-based, 18 years or older, and enrolled members of recognized tribes. The program emphasizes Indigenous values in performing arts, fostering resilience and cultural expression.
Performing Arts Native American Culture & Heritage Arts / Culture Access & Participation

Jennifer Easton Community Spirit Award

First Peoples Fund
Private
United States
Up to US $50,000
The Jennifer Easton Community Spirit Award honors Native artists who have dedicated their lives to sharing cultural knowledge and ancestral gifts. With a grant of $50,000, this award supports artists deeply rooted in their communities, fostering healing and resilience. Nominations are open for practicing artists across various mediums, including music, dance, and storytelling, ensuring the continuation of Indigenous traditions and the enrichment of Native culture.
Native American Culture & Heritage Arts / Culture Access & Participation Folk Art / Traditional Art

Cultural Capital (CC) Fellowship

First Peoples Fund
Private
United States
US $10,000
The Cultural Capital Fellowship offers $10,000 grants to Native artists and culture bearers dedicated to community outreach and cultural preservation. This fellowship strengthens the Collective Spirit of First Peoples artists, emphasizing the importance of passing on ancestral knowledge and maintaining cultural sharing. Eligible applicants must have strong ties to their Native community and be committed to sustaining cultural practices. The fellowship aims to support those who promote generosity, wisdom, and integrity within their communities.
Community Culture & Heritage Folk Art / Traditional Art Native American Culture & Heritage

Artist in Business Leadership (ABL) Fellowship

First Peoples Fund
Private
United States
US $10,000
The Artist in Business Leadership (ABL) Fellowship supports Native artists in building sustainable art-centered businesses. This yearlong program provides $10,000 in funding along with professional development and networking opportunities. Eligible applicants must be 18 years or older, reside in the U.S., and be enrolled in or have lineage from a federally recognized tribe. The fellowship aims to empower artists to thrive within their communities while honoring their cultural heritage.
Art & Culture Native American Culture & Heritage Business Development

IBD Research

Kenneth Rainin Foundation
Private
American Samoa, Guam +4 more
US $150,000 - US $300,000
The Kenneth Rainin Foundation seeks to promote innovative research in Inflammatory Bowel Disease (IBD) by encouraging diverse perspectives from early career investigators and those underrepresented in science. The Innovator Awards do not require preliminary data and are evaluated based on the potential for innovation and scientific merit. Eligible researchers must hold advanced degrees and can apply for funding through their home institutions, fostering groundbreaking ideas that can transform IBD treatment and prevention.
Health & Medicine Digestive System Health & Diseases Crohn’s Disease And Colitis

Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The National Institute on Deafness and Other Communication Disorders (NIDCD) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are seeking innovative research applications for non-invasive imaging technologies to study the human olfactory system. This initiative emphasizes the need for advanced multimodal imaging techniques to enhance diagnostic capabilities for olfactory disorders, addressing challenges posed by the system's unique anatomical features. Collaboration among experts is encouraged to foster impactful research developments.
Bioengineering Biochemistry Biomedical Imaging +2 more

HEAL Initiative: Integrative Management of Chronic Pain and Opioid Use Disorder (OUD) for Whole Recovery: Health Systems

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative aims to address the complex interplay between chronic pain and opioid use disorder (OUD), affecting 40-60% of OUD patients. Through the IMPOWR initiative, this funding opportunity seeks to develop integrated care strategies that enhance treatment delivery at health systems levels. By identifying effective interventions and collaborative care models, the initiative strives to improve patient outcomes in managing both chronic pain and OUD, while emphasizing the roles of various healthcare professionals in this integrated approach.
Epidemiology & Public Health Addiction & Substance Use Disorders Health Care Access & Delivery +3 more

LHGM General Operating Grant

Larry H Miller & Gail Miller Family Foundation
Private
Arizona, Colorado +5 more
Up to US $10,000
The Larry H. & Gail Miller Family Foundation offers General Operating Grants aimed at 501(c)(3) nonprofits that serve the west side of Salt Lake City. Grants of up to $10,000, with an average of $5,000, support initiatives in health, shelter, education, economic self-reliance, and cultural enrichment. Applications are reviewed monthly. Organizations must be registered as nonprofits and align with the Foundation's focus areas to be eligible for funding.
Community Culture & Heritage Basic Human Needs Religion & Spirituality +3 more

Auer, Arthur and Hazel Scholarship Fund

Noble County Community Foundation
Private
United States
Up to US $2,000
The Arthur and Hazel Auer Scholarship Fund, established by Hazel Auer's will, provides financial support to two East Noble seniors each year as they prepare for 4-year bachelor's programs at accredited colleges. Each recipient receives about $500 per semester for the first two years, totaling $2,000. This fund is managed by the Community Foundation of Noble County, which aims to enhance the quality of life in the region through philanthropic efforts.
Education - Higher Education Academic Scholarship Programs

Bats for the Future Fund RFP

National Fish and Wildlife Foundation (NFWF)
Private
American Samoa, Guam +4 more
US $50,000 - US $250,000
The National Fish and Wildlife Foundation (NFWF) invites proposals for the Bats for the Future Fund RFP to combat white-nose syndrome (WNS) affecting bat populations in North America. This initiative seeks to advance treatments, implement management strategies, and support research that enhances bat survival and recovery. A match of 50% of the grant amount is preferred, aimed at fostering innovative conservation efforts and collaboration among stakeholders to ensure the future of affected bat species.
Wildlife Health Mammalian Conservation

PEN/Robert W. Bingham Prize for Debut Short Story Collection (Fiction)

PEN America
Private
United States
US $25,000
The PEN/Robert W. Bingham Prize for Debut Short Story Collection recognizes an outstanding debut collection of short stories by a talented fiction writer. Awarded by PEN America, this prize highlights the literary achievements of new voices in fiction and offers a $25,000 cash prize to support the winner's future work. Established in memory of Robert W. Bingham, it honors his commitment to nurturing young writers and their contributions to literature.
Writing & Literature

PEN/Robert J. Dau Short Story Prize for Emerging Writers (Fiction)

PEN America
Private
United States
US $2,000
The PEN/Robert J. Dau Short Story Prize for Emerging Writers, awarded by PEN America, recognizes twelve emerging writers annually for their debut short story published in a literary outlet. Each winner receives a $2,000 cash prize, and their stories are published in an anthology by Catapult. The prize aims to foster new voices in fiction, inspired by Robert J. Dau's legacy, highlighting the importance of literary excellence and encouraging the next generation of writers.
Writing & Literature

PEN Open Book Award (Multigenre)

PEN America
Private
United States
US $10,000
The PEN Open Book Award, presented by PEN America, recognizes literary works by authors of color published in the U.S. during the year. With a focus on diversity, it awards a $10,000 prize and a residency in Italy to authors who have not yet garnered significant media attention. This award promotes underrepresented voices in literature, celebrating fiction, nonfiction, and poetry that challenge the norms and enrich the literary landscape.
Writing & Literature

PEN/Voelcker Award for Poetry Collection

PEN America
Private
United States
US $5,000
The PEN/Voelcker Award for Poetry Collection, established by a bequest from Hunce Voelcker, is presented annually by PEN America to recognize a distinguished collection of poetry published in the calendar year. This award honors the importance of poetry collections as an art form and is open to all U.S. residents or citizens, regardless of age or poetic style, with a cash prize of $5,000. It aims to celebrate and expand the scope of American poetry.
Writing & Literature

PEN/Diamonstein-Spielvogel Award for the Art of the Essay

PEN America
Private
United States
US $15,000
The PEN/Diamonstein-Spielvogel Award for the Art of the Essay, established by PEN America, honors a distinguished writer whose collection of essays expands their body of work. This prestigious award, with a cash prize of $15,000, recognizes books of individual essays that can explore a specific theme or a variety of subjects. Eligible candidates must be U.S. residents and cannot be debut authors, ensuring the award celebrates established voices in the literary community.
Writing & Literature

PEN/E.O. Wilson Literary Science Writing Award

PEN America
Private
United States
US $10,000
The PEN/E.O. Wilson Literary Science Writing Award honors outstanding writing that effectively communicates complex scientific ideas in an accessible manner. Established by Dr. Edward O. Wilson and supported by notable figures, this award recognizes a single, living author for their work published within the calendar year. The winner receives a $10,000 cash prize, celebrating excellence in the literature of the physical and biological sciences.
Writing & Literature

District of Columbia Grants for Nonprofits Highlights

District of Columbia grants for nonprofits provide funding to support community development, education, public health, and arts programs. The following grants help organizations address local challenges and foster positive change across Washington, D.C.


Search Instrumentl's District of Columbia Grants Database


Discover 290 funding opportunities for nonprofits in Washington, D.C., with $64.4M available. Instrumentl supports organizations by offering deadline tracking, refined grant searches, and funder insights to advance impactful programs in the nation's capital.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : District of Columbia Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ District of Columbia grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ District of Columbia grants for nonprofits over $25K in average grant size

100+ District of Columbia grants for nonprofits over $50K in average grant size

55 District of Columbia grants for nonprofits supporting general operating expenses

200+ District of Columbia grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for District of Columbia grants for Nonprofits?

Most grants are due in the first quarter.

Q1
28.0%
Q2
25.0%
Q3
25.7%
Q4
21.3%

Typical Funding Amounts

What's the typical grant amount funded for District of Columbia Grants for Nonprofits?

Grants are most commonly $50,000.

$250 $250 Min.
$50,000 $50 K Median
$326,838 $326.8 K Average
$19,910,496 $19.9 M Max.
Addiction and Substance Abuse Grants in District of Columbia Aging Grants in District of Columbia Alzheimer's and Dementia Research Grants in District of Columbia Community Health Grants in District of Columbia Grants for Assisted Living Facility in District of Columbia Grants for Autism Programs in District of Columbia Grants for Cancer Nonprofits in District of Columbia Grants for Digestive System Health and Diseases in District of Columbia Grants for Free Clinics in District of Columbia Grants for Global Health in District of Columbia Grants for Heart Disease Research in District of Columbia Grants for HIV / AIDS in District of Columbia Grants For Home Health Care in District of Columbia Grants for Multiple Sclerosis Patients in District of Columbia Grants for Nonprofit Healthcare Programs in District of Columbia Grants for Public Health in District of Columbia Grants for Rare Diseases in District of Columbia Grants for Reproductive Health in District of Columbia Grants for Seniors in District of Columbia Grants for Suicide Prevention in District of Columbia Health and Medical Grants in District of Columbia Health and Wellness Grants for Nonprofits in District of Columbia Health Care Grants in District of Columbia Hearing and Vision Grants in District of Columbia Hospice Grants in District of Columbia Medical Equipment Grants in District of Columbia Mental Health Grants in District of Columbia Neuroscience Grants in District of Columbia Nursing Grants in District of Columbia Nursing Home Grants in District of Columbia Obesity Prevention Grants in District of Columbia Psychology Grants in District of Columbia Quality of Life Grants in District of Columbia School Health Grants in District of Columbia

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