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Best Dorchester County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Dorchester County Grants for Nonprofits. 36,000+ grants are available for a wide range of missions and programs with additional grants in Charleston, Berkeley, and Georgetown counties.

9,000+

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$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,333 Results based on applied filters

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.
Epidemiology & Public Health Patient Care & Services Biomedical Imaging +1 more

DoW Kidney Cancer, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $900,000
The FY26 Kidney Cancer Research Program's Idea Development Award supports innovative research that enhances understanding of kidney cancer, aimed at improving patient outcomes. Proposals should feature a strong hypothesis and a detailed research plan, with team members experienced in kidney cancer research. A unique aspect is the Partnering Principal Investigator option, fostering collaboration between two investigators, ensuring comprehensive project development while allowing for distinct submissions. This award emphasizes impactful partnerships to drive advancements in the field.
Cancer / Oncology Kidney Diseases

DoW Parkinson’s, Early Investigator Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,000,000
The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.
Parkinson’s Disease

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Child Protection Compact Annual Program Statement (362907)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $5,000,000 - US $10,000,000
The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.
Child Welfare Services Human Trafficking

TIP Office International Programs to Combat Human Trafficking Annual Program Statement (362906)

US Department of State: Office to Monitor and Combat Trafficking in Persons
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $10,000,000
The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.
Human Trafficking

Continuing Education and Training Grants

Nebraska Library Commission
State/Local Government
United States
Unspecified amount

Nebraska Library Commission Grants Schedule

Nebraska Library Commission Grants: The Nebraska Library Commission awards grants to Nebraska libraries and library organizations according to the following schedule. These grants are financed with funding made available through the Nebraska Unicameral Legislature or through the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act.

Continuing Education and Training Grants

This year, the Nebraska Library Commission is opening the CE grants to 1) online learning, 2) attending out-of-state conferences or workshops, and 3) larger continuing education projects.

The purpose of these continuing education grants is to assist Nebraska libraries in improving the library services provided to their communities through continuing education and training for their library personnel and supporters. Successful applications will show how the continuing education and/or training proposed will support the library's mission.

For this round of CE and training grants, applications should be for events happening before June 2026. (All reimbursement forms and receipts must be submitted by June 12, 2026.).

Adult Education Library Services

Veterans' Homelessness and Transition Grant

South Carolina Department of Veterans' Affairs
State/Local Government
South Carolina
US $50,000 - US $250,000

Secretary's Intent

The Department's Purpose

The South Carolina Department of Veterans' Affairs exists to serve this state's Veterans, service members, and their families and to promote the value Veterans bring to their communities and their fellow citizens.

Veterans' Homelessness and Transition Grant

The Veterans’ Homelessness and Transition Grant was established on October 16, 2023, to provide funding to organizations that serve homeless Veterans or Veterans at imminent risk of being homeless with resources to obtain permanent housing. The Veterans Homelessness and Transition Grant Program is funded through an appropriation by the South Carolina General Assembly and managed by the South Carolina Department of Veterans’ Affairs (SCDVA).

The grant aims to enhance nonprofit organizations and state agencies' housing assistance programs for Veterans. The South Carolina Department of Veterans' Affairs will award a grant to nonprofit groups and state governmental agencies that assist eligible South Carolina Veterans with housing assistance, utility assistance, rental assistance, or drug addiction treatment and transitional housing programs.

The minimum grant award is $50,000, and the maximum grant award amount is $250,000 per grant cycle. Veteran eligibility is defined by Title 38 of the Code of Federal Regulations, as “a person who served in the active military, naval, or air service and who was discharged or released under conditions other than dishonorable.”

Military & Veterans Services Homelessness Services

Senior Centers and Permanent Improvement Project Grant

South Carolina Department on Aging
State/Local Government
South Carolina
Up to US $350,000

Senior Centers and Permanent Improvement Project Grant

The Older Americans Act identifies the South Carolina Department on Aging (SCDOA) as a leader in the development of multipurpose senior centers. Currently, the state has three nationally certified senior centers. Several additional centers are fully operational but have not yet achieved certification, while others operate solely as group dining sites.

Senior Center Permanent Improvement Project (PIP) Grant Program

 It is the intent of the South Carolina Department on Aging for all multipurpose senior centers to be focal points in their respective communities. The Older Americans Act (OAA) defines a focal point as a facility established to encourage the maximum collocation and coordination of services for older individuals.

A focal point is a facility established to provide local leadership on aging issues, to provide older adults access to services at a central location with customer-oriented staff, and to assist those in the community who have an interest in, or need for, information, resources, or services. All Permanent Improvement Program (PIP) funded Multipurpose Senior Centers shall be focal points of their respective communities.

In 1991, the South Carolina State Legislature established the Senior Center Permanent Improvement Project (PIP) grant program and appropriated $948,000 per year from State Bingo tax ($79,000 monthly) and licensing fee revenues to fund a list of 74 specifically identified capital improvement projects. The total amount of funding required to complete these projects was reached in the year 2000.

The original legislation was amended by the General Assembly in 1997 to continue the program beyond the original list and the State Unit on Aging (hereafter called the SC Department on Aging or SCDOA), was given responsibility for developing an ongoing process to select and fund applications for senior center capital improvement projects. The resulting procedures created a competitive grant process for securing Senior Center PIP funds.

Senior Services Aging / Gerontology Public Infrastructure

DOW Combat Readiness – Medical Research Program Translational Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,450,000
The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.
Crisis Intervention Post-Traumatic Stress Disorder

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

Childhood Asthma in Urban Settings Clinical Research Network

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.
Respiratory Diseases & Systems Asthma

BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.
Neuroscience

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) (362945)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.
HIV / AIDS

Collaborative Network for Clinical Research on Immune Tolerance

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.
Infectious & Parasitic Diseases Immune System Diseases

Clinical Data, Safety and Statistical Centers (CDSSC)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.
Immune System Diseases Allergies & Allergic Diseases

Translational Transplantation Tolerance Cooperative Study Group

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.
Infectious & Parasitic Diseases Organ And Tissue Banks

Great Lakes Bay Pride Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Great Lakes Bay Pride Scholarship, offered by the Saginaw Community Foundation, supports Michigan residents dedicated to promoting respect and acceptance across diverse backgrounds. This scholarship is open to high school seniors and college students pursuing undergraduate or Career and Technical Education (CTE) programs, with awards ranging from $500 to $4,000. Eligible applicants must maintain a minimum GPA of 2.5 and demonstrate commitment through volunteer work in the LGBTQ+ community.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Rural Health Transformation Program: Shoring Up to Sustainability Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $500,000 - US $3,000,000

The Rural Health Transformation Program (RHTP), established under the Working Families Tax Cuts Act signed into law on July 4, 2025, is a federal initiative led by the Centers for Medicare & Medicaid Services (CMS). This program is designed to help state governments strengthen healthcare access, quality, and outcomes in rural communities by transforming the healthcare delivery ecosystem. Through a focus on innovation, strategic partnerships, infrastructure development, and workforce investment, the RHTP aims to create sustainable improvements in rural health systems across the United States. The Shoring Up to Sustainability initiative aims to strengthen the operational and financial resilience of rural healthcare systems in South Carolina by investing in critical facility enhancements and delivering targeted masterclass training for rural providers.

Rural Health Care

Mark Mayden Scholarship

The Community Foundation of Dickinson County Inc.
Private
United States
US $700
The Mark Mayden Scholarship, established in 2006 by the Community Foundation of Dickinson County, honors the legacy of Mark Mayden, a devoted supporter of agribusiness. This $700 scholarship aims to assist hardworking students from Dickinson County in pursuing technical or vocational education, fostering opportunities for future generations. By rewarding initiative and talent, the scholarship reflects Mark's belief in the transformative power of education and hard work, ensuring that deserving students have the support they need to succeed.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Loren Engel Memorial FFA Scholarship

The Community Foundation of Dickinson County Inc.
Private
United States
US $300
The Loren Engel Memorial FFA Scholarship, established by Margaret Engle in 2005, honors Loren Engel’s dedication to agriculture and leadership. This $300 scholarship is available for graduating high school students from Dickinson County who have served as FFA chapter officers, demonstrating commitment to agricultural education. The Community Foundation of Dickinson County aims to support local students pursuing technical or vocational education, ensuring future generations can thrive in their community.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

The Vanguard Award

Remuseum Inc.
Private
United States
US $100,000

The Vanguard

Remuseum announces The Vanguard, an award and accelerator for innovative leaders in the visual and performing arts, in partnership with the Doris Duke Foundation. The Vanguard’s $100,000 annual award will recognize up to ten leaders who are exploring new ways to strengthen arts institutions, and a year-long accelerator will help them refine, implement, and evaluate their ideas. The first award and accelerator of its kind, The Vanguard celebrates leaders who are ready to center the public in their work in new ways, building models for increased relevance and sustainability in the arts.

The Program

The $100,000 grant that accompanies each award will go to that leader’s institution, to support ideas developed in The Vanguard’s 12-month accelerator program. That program begins with a week-long retreat at Shangri La, the Doris Duke Foundation’s global center for culture and ideas in Honolulu, Hawaii, followed by a year of monthly coaching sessions, regional peer gatherings, and collaborative workshops, culminating in a public presentation of their work and findings to the broader arts community. The accelerator and its curriculum, tailored specifically for cultural leaders, has been designed by Jenny Larios Berlin, entrepreneur in the creative and tech sectors and Lecturer at MIT Sloan School of Management, and will be co-taught with Gregory Bunch, entrepreneur and Adjunct Professor of Entrepreneurship at the University of Chicago Booth School of Business, and will be advised by Ethernet Inventors Professor of Entrepreneurship Bill Aulet, Managing Director of the Martin Trust Center for MIT Entrepreneurship.

By year’s end, members of The Vanguard will have built an intellectual kinship with each other while modeling a spirit of innovative leadership for the field. Remuseum will continue evaluating and sharing their work as case studies for cultural organizations broadly, and future classes will continue expanding a Vanguard of leaders (10, then 20, and on) who build models of success for cultural organizations in the 21st Century, allowing arts & cultural institutions not just to survive but to support a stronger and more pluralistic civil society.

Art & Culture Nonprofit Growth & Development Arts / Culture Access & Participation

SC Housing Trust Fund (HTF) — Critical Home Repair Program Grant

South Carolina State Housing Finance and Development Authority
State/Local Government
South Carolina
US $5,000 - US $30,000

South Carolina Housing Trust Fund (HTF)

The South Carolina Housing Trust Fund (SC HTF) is a valuable resource for developing and maintaining safe, quality affordable housing for low to very low-income households within the state. Funding and assistance for eligible home repairs and supportive housing projects are provided through three core programs—The Home Repair Program, Critical Home Repair Program, and Supportive Housing Program. SC Housing administers the HTF program in partnership with other government organizations, non-profit sponsors and affordable housing developers. The HTF program also coordinates its efforts with other federal, state, and local housing assistance programs to achieve maximum benefit for participants.

The Critical Home Repair Program provide financial assistance to help low to very low-income homeowners with essential interior and exterior home repairs to correct life, health and safety issues so that they can live safely in their homes. These programs help to repair or replace major housing systems, including roofs, water heaters and HVAC equipment. It also covers home modifications, such as ramps, to provide accessibility for persons who are disabled. A home inspection is conducted to help identify any additional repairs that may be needed to provide the homeowner with safe and decent living conditions. The Sponsor then coordinates completion of the work with qualified contractors. The homeowner benefits by staying safely in a home that they can continue to enjoy for years to come. Local communities also benefit by maintaining the supply of affordable homes in their area.

Homeownership Equitable & Affordable Housing Energy Efficiency & Conservation

Rural Health Transformation Program: Leveling Up Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $100,000 - US $5,000,000

The Leveling Up initiative aims to expand and integrate proven chronic disease management programs statewide, ensuring rural communities have access to comprehensive, coordinated care for serious and chronic conditions such as diabetes, hypertension, and sickle cell disease. Historically, these programs have been implemented in limited regions due to resource constraints, leaving rural areas underserved and often last to benefit from advancements in chronic care. This grant opportunity seeks proposals from eligible organizations to expand chronic disease programs.

Chronic Illnesses Rural Health Care

Rural Health Transformation Program: Connections to Care Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $100,000 - US $10,000,000

The Connections to Care initiative aims to modernize and expand digital infrastructure across South Carolina’s rural healthcare ecosystem. This grant opportunity seeks proposals from eligible organizations to implement or enhance electronic health records (EHRs) and remote patient monitoring (RPM).

Health Information Technology Rural Health Care

Dorchester County Grants for Nonprofits Highlights

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Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Dorchester County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Dorchester County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Dorchester County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081