Best El Dorado County Grants for Nonprofits in California

American Cancer Society

The mission of the American Cancer Society is to improve the lives of people with cancer and their families through advocacy, research, and patient support, to ensure everyone has an opportunity to prevent, detect, treat, and survive cancer.

ACS Research Priority Areas

The American Cancer Society (ACS) has identified these 6 areas to categorize and track the research we fund to help advance our mission. Applicants (except Institutional Research Grants and Professor grants) are asked to select at least 1 of these research areas that aligns with their proposal:

• Etiology (causes of cancer)
• Obesity/Healthy Eating and Active Living (HEAL)
• Screening and Diagnosis
• Treatment
• Survivorship
• Health Equity Across the Cancer Continuum

Research Scholar Grants

Research Scholar Grants (RSG) provide support for independent, self-directed researchers.

Applicants' institutions must provide space and other resources customary for independent investigators.

Grant proposals are investigator-initiated and may pursue questions across the cancer research continuum, as long as they fit within an American Cancer Society (ACS) priority research area.

These grants typically contribute to the cost of salaries, consumable supplies, and other miscellaneous items required in the research. 

Research Scholar Grants are funded up to $215,000 per year (direct costs), plus 10% allowable indirect costs, with a project period up to four years.

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

The Easement Restoration and Stewardship program, funded by the USDA NRCS, focuses on restoring and managing Wetland and Floodplain Easements. It includes developing restoration plans, conducting assessments, and implementing stewardship activities to enhance ecological health. Awardees will collaborate with NRCS personnel to ensure effective restoration design and maintenance strategies, fostering sustainable landscapes. This initiative addresses critical habitat conditions and promotes long-term environmental benefits for protected lands.

The FY 2027 Notice of Funding Opportunity for the Infrastructure Investment and Jobs Act (IIJA) FAA Contract Tower Competitive Grant Program offers up to $100 million for airport traffic control tower projects. This initiative aims to support airports in modernizing and repairing aging infrastructure, ensuring safety and efficiency in air traffic management. Eligible projects may involve construction, rehabilitation, or installation of essential air traffic control equipment, enhancing the operational capabilities of the nation's airports.

The DOJ FY 2026 ANGEL Grant Program aims to enhance public safety by funding state, local, and tribal government initiatives to combat violent crime committed by criminal illegal aliens. This program supports hiring law enforcement personnel, retaining critical staff, and acquiring advanced technology. The objective is to prevent harm to American citizens and support Homeland Security Task Force operations. Applications must be submitted by October 27, 2026, to qualify for funding.

The Deployed Warfighter Protection FY27 program aims to safeguard military personnel from disease-carrying arthropods, including ticks and mosquitoes. It seeks innovative research to develop new insecticides, improve existing formulations, and enhance personal protection technologies. The initiative also focuses on effective pesticide application equipment, addressing both current and emerging arthropod threats. This program is crucial for maintaining the health and safety of deployed military forces.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing Type 1 diabetes research by exploring the innate immune system's role in disease onset. This initiative aims to identify genetic and environmental factors contributing to Type 1 diabetes through multidisciplinary teams. By employing innovative methodologies, the program seeks to determine how immune responses affect pancreatic tissues, potentially leading to early detection and prevention strategies for at-risk individuals.

The Collaborative Centers in Children’s Environmental Health Research and Translation program aims to establish a national network of research centers focused on improving children's health through innovative research and public health strategies. By fostering collaboration within the children’s environmental health community, these centers will lead the way in translating scientific findings into actionable practices, ensuring a healthier future for children while addressing emerging environmental threats.

The Immune Drivers of Autoimmune Disease (IDAD) network, supported by NIAID, aims to uncover early triggers and mechanisms of autoimmunity to prevent disease. Key initiatives include developing predictive tools and biomarkers, fostering preclinical cohorts, and utilizing AI and big data. The network will leverage shared infrastructure for collaborative research, managed by the IDAD Network Coordinating Center, which ensures coordination and resource sharing among awardees. This initiative is crucial for advancing understanding and prevention of autoimmune diseases.

The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.

The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.

The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.

The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Cooper Black Award for Creativity

The Copper Black Award for Creative Achievement honors Mensa members whose innovative solutions and practical creativity have brought meaningful benefits to the world.

Details

The Copper Black Award annually recognizes Mensa International members who have demonstrated a specific creative achievement with practical value. This award honors innovations that have been implemented, at least in part, to benefit others.

Award Components

Workforce Development Solicitations for Proposals

Program Year 2026–27

The Employment Development Department, in close collaboration with the California Labor and Workforce Development Agency, announces the availability of up to $1.5 million in funding through the Workforce Innovation and Opportunity Act Governor’s Discretionary 15 percent fund for the Emergency Medical Services Technical Assistance (EMS TA) grant for PY 26-27.

This funding supports the continued implementation, improvement, and long-term sustainability of established EMS Corps programs across California. The PY 26–27 grant is designed to strengthen existing programs by ensuring fidelity to the EMS Corps model, improving participant outcomes, and supporting consistent statewide quality.

The FY 2027 Continuation of Solicitation invites applications to support various program areas, including Advanced Scientific Computing, Basic Energy Sciences, Fusion Energy Sciences, and more. This annual open solicitation from the Department of Energy (DOE) allows research proposals throughout the fiscal year. Applications must align with SC's mission and can be submitted until September 30, 2027, or until a new solicitation is issued. Detailed submission processes are outlined in 10 C.F.R. part 605.

The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.

The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.

The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.

The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.

The Prioritization Process Pilot Program (PPPP) Competitive Grant Program, funded by the DOT Federal Highway Administration, offers up to $26 million for innovative transportation planning in FYs 2024-2026. Grants of up to $2 million will support the development of transparent, data-driven prioritization processes for project selection in transportation plans, ensuring that funded projects deliver public benefits and meet community needs.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

WRF was formed in 2018 through the integration of three highly respected research collaboratives: WateReuse Research Foundation, Water Environment Research Foundation, and Water Research Foundation. Separately, these organizations focused on research to support varied segments of the water sector—water reuse, wastewater and stormwater, and drinking water, respectively. Now a One Water organization, WRF delivers the research programming the sector needs to address the most pressing water issues holistically.

5425 - Assessing and Managing Manganese Behavior in Drinking Water Distribution and Premise Plumbing Systems

Grant Information

• Characterize spatial and temporal variability of manganese (Mn) concentrations and speciation in distribution systems and potential impacts in premise plumbing.
• Investigate Mn speciation and its influences on interactions with water chemistry, corrosion control treatment, and complexing agents, and assess implications for Mn occurrence, stability, and release in distribution systems and premise plumbing.
• Evaluate the relationships between Mn stability and release, including long-term legacy deposit mobilization, in relation to chemical, hydraulic, and biological processes in distribution systems.
• Evaluate strategies for mitigating Mn accumulation and release, including corrosion control treatments such as phosphate blends, and assess operational practices such as flushing and other system maintenance activities.
• Recommend monitoring strategies to identify system-specific risks, support detection of Mn accumulation, and inform responses to anticipated regulatory changes.

The USDA SBIR/STTR programs aim to enhance scientific excellence and technological innovation through federal funding, fostering a robust national economy. By supporting small businesses in addressing federal research needs, these programs encourage the commercialization of federally funded research. Specifically, the STTR program promotes partnerships between small businesses and research institutions, such as universities and federal laboratories, to advance cooperative research and development efforts.

The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.

The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.