Best El Dorado County Grants for Nonprofits in California

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.

The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.

The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.

California Department of Education

California will provide a world-class education for all students, from early childhood to adulthood. The Department of Education serves our state by innovating and collaborating with educators, schools, parents, and community partners. Together, as a team, we prepare students to live, work, and thrive in a multicultural, multilingual, and highly connected world.

Public Charter Schools Grant Program Start-Up Subgrant

Purpose and Background

The PCSGP is a subgrant program funded by the federal Charter Schools Program (CSP), authorized under Title IV, Part C of the Elementary and Secondary Education Act (ESEA) of 1965, as amended by the Every Student Succeeds Act (ESSA) (20 United States Code [U.S.C.] 7221–7221j (External Link). The PCSGP is a discretionary grant program. California was awarded approximately $93 million in grant funds for 2024–29. States that are awarded these federal funds distribute them in subgrants to charter school developers, known as PCSGP Start-Up Subgrants in the state of California, to assist in the development and initial operations of newly established or conversion charter schools as well as to assist in the expansion and replication of high-quality charter schools.

PCSGP Start-Up Subgrants identify funding levels and terms into three subgrant types: New School (Planning and Implementation), Replication, and Expansion. For FY 2026, the CDE has an approved pipeline and budget to award approximately 26 subgrants. The actual number and type of subgrants awarded during each RFA competition may vary based on demand. If all authorized awards are not approved for funding, the CDE may open additional RFA competition events for new applicants until allocated funds have been awarded.

California Governor's Office of Emergency Services

With over 38 million residents (12 percent of the US population), the State of California is the most populous state in the nation and has the third largest land area among the states (163,695 square miles). California is culturally, ethnically, economically, ecologically, and politically diverse, and maintains the eighth largest economy in the world with 13 percent of the U.S. gross domestic product. California also faces numerous risks and threats to our people, property, economy, environment and is prone to earthquakes, floods, significant wildfires, prolonged drought impacts, public health emergencies, cybersecurity attacks, agricultural and animal disasters, as well threats to homeland security. Cal OES takes a proactive approach to addressing these risks, threats, and vulnerabilities that form the basis of our mission and has been tested through real events, as well as comprehensive exercises that help us maintain our state of readiness to plan for and mitigate impacts.

Intimate Partner Violence Prevention (FD) Program Supplemental

Purpose

To create or expand Intimate Partner Violence, Sexual Assault, and Teen Dating Violence prevention programs.

Description

The purpose of the Intimate Partner Violence Prevention (FD) Program is to prevent intimate partner violence, including teen dating violence, and sexual assault.

Requires Matched Funding: 20%

The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

California Department of Fish and Wildlife

CDFW’s MISSION is to manage California's diverse fish, wildlife, and plant resources, and the habitats upon which they depend, for their ecological values and for their use and enjoyment by the public.

Natural Community Conservation Planning Local Assistance Grant Program

Description

The California Department of Fish and Wildlife seeks proposals for highest priority projects associated with the implementation of an NCCP. The intention of this Proposal Solicitation Package (PSP) is to solicit proposals of the highest quality that are consistent with the goals of the NCCP Program. Proposals must address the highest priority tasks associated with the implementation of an NCCP such as:

• Management Activities: Immediate management actions on newly acquired NCCP reserve lands.
• Restoration/Enhancement: Restoration or enhancement of habitats or species populations on NCCP reserve lands.
• Monitoring: Design and implementation of biological monitoring programs identified in an NCCP, including the establishment of sampling methods, monitoring plots, data collection, management, and analysis.
• Reserve Management Plans: Development and implementation of individual reserve management plans.
• Mapping: New or updated mapping in support of NCCP management or monitoring activities, such as vegetation community mapping.
• Targeted Studies for Adaptive Management: Studies to evaluate management actions for covered habitats or species, and whether such actions are meeting stated goals or require adjustments through adaptive management.
• Other: Other non-land acquisition priority tasks, identified by the applicant and implementing partners, which are needed to ensure effective implementation of the NCCP.

St. Ignace Area Community Foundation: CTE Technical Scholarship

The St. Ignace Community Fund annually awards scholarships assisting students with higher education, technical training, vocational training or retraining based largely on acknowledgement of student responsibility, community service, and civic involvement. These Scholarships are made possible through the generosity of donors to the various accounts within the St. Ignace Area Community Fund. Some accounts specifically are awarded to recognize higher education in the areas of special education, vocational/technical careers, teaching, law enforcement, and health care.

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

Solís Policy Institute State Fellowship

For over twenty years, The Dr. Beatriz María Solís Policy Institute (SPI) State has created feminist policy for the future of California. SPI State is a policy advocacy and leadership training fellowship for advocates and activists who work in non-profit or grassroots organizations. With nearly 60 laws passed, this fellowship is built for women and gender-expansive folks across California who know that change happens when we bring lived experience into legislative spaces. Join this new wave of policy leaders who are grounded in community, driven by justice, and take up space.  

Criteria

• Depth of Issue Expertise
• Collaborative Spirit
• Commitment to Policy Advocacy Work
• Organizational Support
• Commitment to Building Organizational Capacity
• Time Availability
• Understanding of and interest in applying anti-racist, intersectional and transgender justice lenses to policy advocacy

The Readiness and Recreation Initiative (RARI) by the National Park Service aims to enhance outdoor recreation and support compatible land uses near military installations. This program, funded through the Land and Water Conservation Fund, provides up to 50% of project costs, encouraging collaboration with the Department of War. Projects must involve land acquisition and align with national priorities to ensure public outdoor access in perpetuity, directly benefiting both military and civilian communities.

The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Stephany June Bryan: Bold Spirit of Achievement Scholarship

The Hogg Foundation for Mental Health is offering ten $5,000 scholarships in honor of Stephany June Bryan to individuals facing personal and financial barriers to achieving their educational or career goals due to the impact of living with a mental health challenge and/or supporting a loved one with a mental health challenge.

You do not need to be enrolled in a program at the time you submit your application. However, you will need to provide enrollment verification and/or a certificate of completion when/if it is awarded.

About BlackRock

We’re a global asset manager and technology provider dedicated to helping more and more people experience financial well-being. We help millions of people invest to build savings that serve them throughout their lives. The BlackRock Foundation which funds and partners with organizations that strengthen financial security for more people,

BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

• Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
• Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.

AΩA is committed to preparing future leaders in medicine and health care. Leadership is about making a positive difference and can be developed through education, observation, experience, and by working with leader mentors. Service learning provides excellent opportunities for students to develop as servant leaders. Only one team from each school may be nominated.

The National Centers for Biomedical Imaging and Bioengineering (NCBIB) provide critical resources for biomedical imaging and bioengineering research. This funding opportunity supports the development of innovative technologies tailored to the needs of basic, translational, and clinical researchers. NCBIB facilitates technology access, training, and dissemination, enhancing collaboration and advancing the field. Applications are encouraged to foster advancements that address complex biomedical challenges.

The Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP) aims to strengthen viral hepatitis surveillance and prevention efforts across the United States. By enhancing outbreak response capabilities and promoting testing and treatment in high-impact settings, this initiative seeks to improve public health outcomes. Key components include partnerships, strategic planning, and perinatal hepatitis C programs, ultimately striving for better access to prevention and treatment services, aligning with CDC priorities.

The Evelyn Manning Potter and Vivian Grove Strunk Memorial Scholarship, administered by the Community Foundation of Washington County, MD, supports students pursuing careers in the administrative professional field. Established in memory of two dedicated professionals, this scholarship aims to provide financial assistance to qualified individuals, promoting their educational and career aspirations. The foundation offers over 100 scholarships, reflecting its commitment to enhancing the community's quality of life and supporting local talent.

The Carol D. Garling Scholarship, established by Carol D. Garling, provides financial assistance to students pursuing a post-secondary education who have completed at least 30 credit hours at an accredited institution. Offered by the Community Foundation of Washington County, MD, this scholarship is part of a larger initiative to support local students and promote educational advancement within the community. Applications are accepted annually from January to April 1st, encouraging both high school graduates and non-traditional students.

The Bill Dorsey Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, offers scholarships to students at the Barbara Ingram School for the Arts (BISFA). Designed for rising sophomores, juniors, and seniors, this fund helps cover costs related to their arts discipline. Applications are available in the Fall, supporting the foundation's mission to enhance educational opportunities for local students and nurture their artistic talents.

The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.

The WaterSMART Cooperative Watershed Management Program offers funding to eligible entities for developing local solutions to water management issues. This initiative supports watershed group development, restoration planning, and project design, promoting stakeholder cooperation and improving water reliability. It aligns with key priorities from the Trump administration, addressing complex water challenges and enhancing federal grant oversight. By facilitating these efforts, the program aims to stretch limited water resources and foster collaborative solutions among diverse stakeholders.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.