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Best Greenville County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Greenville County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Charleston County, Richland County, and Horry County.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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Crossing the Divide – Best Practices for Addressing Local and Privately-Owned Lateral Sewer Issues RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5419 - Crossing the Divide – Best Practices for Addressing Local and Privately-Owned Lateral Sewer Issues

Grant Information

To provide water resource recovery facilities (WRRFs) and collection system operators with an interactive manual of practice for implementing inflow and infiltration (I&I) and obstruction management programs with a focus on municipal and privately owned lateral sewers in complex legal, regulatory, and multi-jurisdictional environments.

Water Resource Management Sanitation & Clean Drinking Water Environmental Contamination & Pollution

Comparison of PFAS Contributions to Agricultural Systems RFP

Water Research Foundation
Private
United States
Up to US $400,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5413 - Comparison of PFAS Contributions to Agricultural Systems

Grant Information

  • Report per- and polyfluoroalkyl substance (PFAS) concentrations from a variety of agricultural inputs, including animal manures, fertilizers, pesticides, composts, soil amendments, seed coatings, and biosolids-based products.
  • Compare the impact of the various agricultural inputs on PFAS concentration in the soil profile over varying timeframes.
  • Evaluate the fate and transport of different inputs to PFAS contributions in agricultural systems at field-scale.
  • Determine the relative contributions from biosolids-based products and other inputs to help develop and prioritize risk management strategies.
Sustainable Agriculture & Agroecology Farms & Farming Soil Science +1 more

Adaptive Control Frameworks to Unlock Full-Scale BNR Potential RFP

Water Research Foundation
Private
Countries
Up to US $300,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5424 - Adaptive Control Frameworks to Unlock Full-Scale BNR Potential

Grant Information

  • Identify and categorize the dominant failure modes of current aeration and process control implementations under real-world operating conditions.
  • Develop guidance on data and instrumentation requirements for utilities to support adaptive control, including the characterization of existing sensor infrastructure and the use of soft sensors where hard sensors are limited.
  • Develop practical adaptive control frameworks and implementation guidance that utilities can deploy without dependence on proprietary black-box tools or specialized data science expertise, including hybrid approaches that augment conventional controls with data-driven models (e.g., artificial intelligence (AI)/machine learning (ML), digital twins) for variable flow and concentration conditions.
  • Benchmark control performance against biological capacity indicators across multiple full-scale facilities to quantify the gap between achievable and realized biological nutrient removal (BNR) performance.
Water Resource Management Carbon / Greenhouse Gas Reduction Hydrology

Validating Reverse Osmosis Conductivity Profiling for Pathogen Log Reduction Value Credit RFP

Water Research Foundation
Private
Countries
Up to US $500,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5432 - Validating Reverse Osmosis Conductivity Profiling for Pathogen Log Reduction Value Credit

Grant Information

  • Validate conductivity profiling against pathogen removal by establishing the relationship between conductivity-profile response and MS2 bacteriophage removal under intact and controlled membrane integrity-defect conditions.
  • Demonstrate the robustness and applicability of conductivity profiling across representative reverse osmosis conditions, including new and aged membranes, different defect types and severities, operating conditions, variations in feedwater quality/composition/salinity, and temperature.
  • Develop a validation implementation framework that defines testing procedures, log removal value calculation methods, sensitivity and performance criteria, continuous monitoring, alarm/response thresholds, and operational requirements needed to support regulatory pathogen log removal values credit for reverse osmosis.
Sanitation & Clean Drinking Water Water Resource Management Hydrology

Atlassian Foundation Grant

Atlassian Foundation
Corporate
Countries
Up to US $1,000,000

A better world, built with better teamwork

We bring Atlassian's funding, tools and teamwork expertise to help nonprofits drive greater impact.

Our mission

Atlassian's mission is to unleash the potential of every team. The Atlassian Foundation extends that mission to teams solving the world's hardest problems.

Atlassian Foundation – Open Call for Proposals

The Atlassian Foundation is deploying US$8 million over the next two years to help disadvantaged learners thrive in the AI era. If you're driving collective action in this space, we want to hear from you.

Reshaping education for the AI era will take teamwork

The Atlassian Foundation focuses on education because it's the most empowering force in the world – it's the key to breaking cycles of poverty and disadvantage.

But that key is slipping out of reach for far too many. UNESCO estimates that more than 250 million children are out of school. And for those in the classroom, learning isn't guaranteed: 57% of children worldwide (nearly one billion) lack the basic skills they need for the era they're growing up in. AI can expand access and accelerate learning. It can also widen inequality where it lands unevenly.

No single organisation can tackle a challenge this complex. That's why the Atlassian Foundation is backing collective action: coordinated efforts by multiple players to solve shared problems at scale. Atlassian's mission is to unleash the potential of every team, so we're uniquely positioned to power these efforts. We've spent 20+ years learning what makes teams work well together, and we're offering that expertise – plus our funding, tools and hands-on support – to help collective action initiatives drive greater impact.

We believe a better world is built with better teamwork, and collective action is teamwork at its most ambitious. Together, we want to shape a future where emerging technology closes gaps for learners the current system leaves behind, rather than widening them.

About this open call

In this open call, we're seeking partnerships with collective action initiatives that are working to improve education for disadvantaged learners in the AI era.

What our partners will receive

Each partnership will include:

Technology Access & Digital Literacy Artificial Intelligence (AI) Educational Access & Equity

Early Career Mini-Grant

Mensa Education And Research Foundation
Private
Countries
US $2,500

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

Neuroscience Education Academic Success & Enrichment

Mensa Foundation: Catalyst Grant

Mensa Education And Research Foundation
Private
Countries
US $10,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Catalyst Grant

Early-stage funding for bold ideas that deserve a chance to move forward. Open to anyone, from any background, with an idea worth exploring.

Details

Giving Ideas a First Chance

$10,000 in annual funding helps promising ideas take their next step.

The Catalyst Grant supports early-stage ideas that demonstrate originality and the potential for meaningful impact.

Funding may support one project or be shared among several, depending on the applications received and where funding can make the greatest difference.

Ideas can come from any discipline or background. They may grow from lived experience, independent inquiry, academic research, creative work, or connections between fields.

Funded projects should broadly align with the Mensa Foundation’s mission to unleash intelligence for the benefit of humanity.

Neuroscience Art & Culture Education +2 more

Mensa Foundation: Copper Black Award

Mensa Education And Research Foundation
Private
Countries
US $1,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Cooper Black Award for Creativity

The Copper Black Award for Creative Achievement honors Mensa members whose innovative solutions and practical creativity have brought meaningful benefits to the world.

Details

The Copper Black Award annually recognizes Mensa International members who have demonstrated a specific creative achievement with practical value. This award honors innovations that have been implemented, at least in part, to benefit others.

Award Components

Humanities & Social Science STEM / STEAM Education

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $5,000 - US $10,000,000
The FY 2027 Continuation of Solicitation invites applications to support various program areas, including Advanced Scientific Computing, Basic Energy Sciences, Fusion Energy Sciences, and more. This annual open solicitation from the Department of Energy (DOE) allows research proposals throughout the fiscal year. Applications must align with SC's mission and can be submitted until September 30, 2027, or until a new solicitation is issued. Detailed submission processes are outlined in 10 C.F.R. part 605.
Energy Science Physics +1 more

Dairy Business Innovation Initiatives Program (DBI) Fiscal Year 2026

USDA: Agricultural Marketing Service (AMS)
Federal Government
United States
US $2,300,000 - US $3,450,000
The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.
Agriculture Agricultural Economics Business Development

WATER RESOURCES RESEARCH ACT PROGRAM NATIONAL COMPETITIVE GRANTS FY2026 (104g General)

US Department of the Interior: Geological Survey (USGS)
Federal Government
American Samoa, Guam +5 more
Up to US $120,000
The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.
Hydrology Freshwater Conservation Environmental Policy

Fiscal Year 2026 Wildlife Crossings Pilot Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.
Land / Habitat Conservation Community / Public Safety Wildlife Health +1 more

The Science, Mathematics and Research for Transformation (SMART) Scholarship for Service Program Cooperative Agreement

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $1,300,000,000
The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.
Education - Higher Education Workforce Preparation & Job Readiness STEM / STEAM Education

Prioritization Process Pilot Program (PPPP) Competitive Grant Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The Prioritization Process Pilot Program (PPPP) Competitive Grant Program, funded by the DOT Federal Highway Administration, offers up to $26 million for innovative transportation planning in FYs 2024-2026. Grants of up to $2 million will support the development of transparent, data-driven prioritization processes for project selection in transportation plans, ensuring that funded projects deliver public benefits and meet community needs.
Urban Planning Community Development & Revitalization Public Infrastructure

GAP Audit Reimbursement Cost Share

South Carolina Department of Agriculture
State/Local Government
South Carolina
Unspecified amount

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

GAP Audit Reimbursement Cost Share

Through funding from the USDA AMS Specialty Crop Block Grant Program (#25SCBPSC1280), South Carolina growers can now get reimbursed for 90% of the costs associated with a GAP audit completed while funds are available. To help growers receive reimbursements faster, they may choose to receive two separate payments. A grower may submit Part I of the application as soon as they have paid the SCDA portion of the audit without having to wait on the USDA invoice. Then, once the grower has paid the USDA portion, they may submit Part II of the application to receive 90% of that amount as well. However, a grower may choose instead to submit both parts together to receive one larger payment. See examples below:

Example 1

Smith Farm submits a paid receipt from SCDA Fruit & Vegetable Inspections for $575 with Part I of the application and receives a check for $517.50 approximately four weeks later. ($575 × 90%)

Next, the Smiths receive the USDA invoice, pay $345 to USDA, then submit the paid receipt with Part II of the application to USDA. About four weeks later the Smiths receive a second check for $310.50. ($345 × 90%)

Example 2

Jones Farm is charged the same as the Smiths above but chooses to wait until they have paid both invoices to submit the application. In this case, they may submit both Parts I and II of the application at the same time. The Jones’ will receive one check approximately four weeks later for $828.

($575 + $345 = $920 × 90%)

Applicants must submit a complete application package including all of the following:

  • Completed application with correct information
  • A state vendor registration number
  • Complete, detailed answers to the questionnaire included in the application (Note: This information impacts our ability to seek continued funding for this program).
  • Your agreement to provide follow-up information regarding the impact of GAP certification (Note: This information impacts our ability to seek continued funding for this program).
  • A copy of the paid receipt or other proof of payment for the reimbursement you are requesting. We will not send checks unless we have this.
Agricultural Crops

Cold Storage Cost Share Program

South Carolina Department of Agriculture
State/Local Government
South Carolina
Up to US $750

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Cold Storage Cost Share Program

The South Carolina Department of Agriculture and South Carolina Specialty Crop Growers Association are pleased to announce continued funding for the Cold Storage Cost Share Program. Through the USDA Specialty Crop Block Grant Program, farmers who are members of the South Carolina Specialty Crop Growers Association may receive reimbursement up to $750 for the purchasing and installing up to two (2) Cool Bot cooler systems. Nonmembers may receive reimbursement up to $325, for installing one (1) Cool Bot cooler system. The Cool-Bot utilizes a traditional window-unit air conditioner, multiple sensors, a heating element, and a programmed micro-controller to direct your air conditioner’s compressor to cool the room to 36° F, without ever freezing up.

Agricultural Crops

Market Development Educational Conference Cost Share Program

South Carolina Department of Agriculture
State/Local Government
South Carolina
Unspecified amount

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Market Development Educational Conference Cost Share Program

The SC Specialty Crop Growers Association is partnering with the SC Department of Agriculture (SCDA) to promote the specialty crop industry through a cost share program that will assist growers in attending domestic industry trade show and educational conferences. Attendance at various trade shows and conferences will equip South Carolina’s specialty crop growers with the latest and most current research based educational information on topics such as pest management, sustainability, production practices, food safety, and regulatory issues, which are essential in expanding the specialty crop industry.

Through funding from the USDA Specialty Crop Block Grant, this cost share program will cover 50% of registration fees for attending a specialty crop-focused educational conference for up to 2 growers per company. The cost share will not cover costs of merchandise, travel, food, or lodging.

Reimbursements are available on a first come first serve basis until funds are depleted. A farm may submit their application and primary source receipts after each event or following the end of the conference season.

Graduation Rule

Growers cannot exceed more than two consecutive years in the program, although they can reapply after one year hiatus.

Agricultural Crops

Academic Matching Grant

South Carolina Research Authority
Private
South Carolina
US $5,000 - US $15,000

South Carolina Research Authority

SCRA is a public, non-profit corporation chartered in 1983 by the State of South Carolina. Its mission is to fuel South Carolina’s innovation economy by accelerating technology-enabled growth of academia, entrepreneurship, and industry. SCRA's vision is focused in becoming a leading catalyst in making South Carolina the top choice for technology-focused industry, entrepreneurs, investors, and academics.

SCRA supports its stakeholders in key technology sectors, which include but are not limited to, Advanced Materials/ Manufacturing; Life Sciences; Clean Tech, Sustainability, and Resilience, and Information Technology. SCRA grant funding is made possible, in part, by Industry Partnership Fund (IPF) contributions. Contributors receive a dollar-for-dollar South Carolina income tax credit, making it a no-cost way to create a direct, positive economic effect and job creation. 

Academic Matching Grant 

Managed by the Academic Innovations team, the objective of the Academic Matching Grant is to expand academic engagement in research and development by validating and advancing technology concepts towards the potential of a license opportunity, and/or company formation. Key milestones include: market opportunity and technical feasibility, in the IDEATION stage of startup development. 

Qualifying technologies are recommended by the institution’s Technology Transfer Office, or equivalent; Institutions are responsible for the technical review and prioritization of applications, and review opportunities with the Academic Innovations team. Based upon the review, SCRA will provide application materials and instructions. 

Academic Success & Enrichment Emerging Technology Development

Assessing and Managing Manganese Behavior in Drinking Water Distribution and Premise Plumbing Systems RFP

Water Research Foundation
Private
Countries
Up to US $400,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

WRF was formed in 2018 through the integration of three highly respected research collaboratives: WateReuse Research Foundation, Water Environment Research Foundation, and Water Research Foundation. Separately, these organizations focused on research to support varied segments of the water sector—water reuse, wastewater and stormwater, and drinking water, respectively. Now a One Water organization, WRF delivers the research programming the sector needs to address the most pressing water issues holistically.

5425 - Assessing and Managing Manganese Behavior in Drinking Water Distribution and Premise Plumbing Systems

Grant Information

  • Characterize spatial and temporal variability of manganese (Mn) concentrations and speciation in distribution systems and potential impacts in premise plumbing.
  • Investigate Mn speciation and its influences on interactions with water chemistry, corrosion control treatment, and complexing agents, and assess implications for Mn occurrence, stability, and release in distribution systems and premise plumbing.
  • Evaluate the relationships between Mn stability and release, including long-term legacy deposit mobilization, in relation to chemical, hydraulic, and biological processes in distribution systems.
  • Evaluate strategies for mitigating Mn accumulation and release, including corrosion control treatments such as phosphate blends, and assess operational practices such as flushing and other system maintenance activities.
  • Recommend monitoring strategies to identify system-specific risks, support detection of Mn accumulation, and inform responses to anticipated regulatory changes.
Sanitation & Clean Drinking Water

Small Business Innovation Research and Small Business Technology Transfer Programs Phase II (364020)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
American Samoa, Guam +4 more
US $600,000 - US $650,000
The USDA SBIR/STTR programs aim to enhance scientific excellence and technological innovation through federal funding, fostering a robust national economy. By supporting small businesses in addressing federal research needs, these programs encourage the commercialization of federally funded research. Specifically, the STTR program promotes partnerships between small businesses and research institutions, such as universities and federal laboratories, to advance cooperative research and development efforts.
Entrepreneurship Economic Services & Development Emerging Technology Development +1 more

Technical Assistance and Training Grant Program (364019)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.
Rural Development Public Infrastructure Fish Conservation

Solid Waste Management Grant Program (364018)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.
Freshwater Conservation Environmental Contamination & Pollution Environmental Health +1 more

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $190,000 - US $500,000
The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.
Biology Health & Medicine Emerging Technology Development

FY2026/2027 Community Compass Technical Assistance and Capacity Building Program Notice of Funding Opportunity

US HUD: Office of Community Planning and Development (CPD)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $35,000,000
The FY2026/2027 Community Compass Technical Assistance and Capacity Building Program provides competitive grants to organizations capable of delivering technical assistance (TA) to communities served by HUD. With up to $86 million available, recipients are expected to develop educational tools, collaborate with HUD, and show a strong record of performance. This initiative aims to enhance community systems, support high-priority projects, and ensure effective training delivery, fostering impactful outcomes across the nation.
Community Services Nonprofit Growth & Development

Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.
Mental Health & Psychiatric Diseases Health Care Access & Delivery

Landmarks of History and Culture and Summer Institutes

National Endowment for the Humanities
Federal Government
American Samoa, Guam +4 more
Up to US $460,000
The National Endowment for the Humanities invites K-12 teachers and higher education faculty to apply for the Landmarks of American History and Culture and Summer Institutes program. This initiative aims to enhance humanities education through professional development opportunities, fostering a deeper understanding of historical and cultural landmarks. Participants will engage in enriching experiences designed to improve teaching practices and student learning outcomes in the humanities.
Humanities & Social Science Community Culture & Heritage Teacher Development & Training

Greenville County Grants for Nonprofits Highlights

Looking for Greenville County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Greenville County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Greenville County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

68 Greenville County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

14 Greenville County grants for nonprofits over $25K in average grant size

13 Greenville County grants for nonprofits over $50K in average grant size

12 Greenville County grants for nonprofits supporting general operating expenses

62 Greenville County grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Greenville County grants for Nonprofits?

Most grants are due in the third quarter.

Q1
24.4%
Q2
22.6%
Q3
30.3%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Greenville County Grants for Nonprofits?

Grants are most commonly $10,000.

$500 $500 Min.
$10,000 $10 K Median
$218,238 $218.2 K Average
$5,000,000 $5 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Greenville County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Greenville County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Greenville County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081