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Best Greenville County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Greenville County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Charleston County, Richland County, and Horry County.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,294 Results based on applied filters

AHNS Endocrine Surgery Section ThyCa: Thyroid Cancer Survivors’ Association Award for Thyroid Cancer Research Grant

American Head & Neck Society (AHNS)
Association/Society
Canada, United States
Up to US $10,000
The AHNS Endocrine Surgery Section ThyCa Research Grant offers $10,000 for one year to support innovative research projects focused on thyroid cancer. Eligible candidates include U.S. or Canadian AHNS members, including medical students and faculty. Proposals should advance understanding of thyroid cancer's diagnosis, prevention, and treatment. Preference is given to early-stage investigators or those pursuing new inquiries. Applications require letters of support and a detailed budget, with funding limitations on indirect costs.
Cancer / Oncology Thyroid Cancer Otorhinolaryngology

AES Seed Grants

American Epilepsy Society
Private
United States
Up to US $20,000
The American Epilepsy Society offers Seed Grants to support established researchers in exploring innovative research methodologies and collaborations. These grants aim to foster new lines of inquiry in epilepsy research. Notably, proposals that align with specific partner priorities may enjoy waived eligibility criteria, enhancing funding opportunities. This initiative seeks to advance understanding and treatment of epilepsy through novel research avenues.
Epilepsy

Combined Pilot Research Grants: PSRC/PSF

Plastic Surgery Foundation
Private
Canada, United States
Up to US $15,000
The Combined Pilot Research Grants program, supported by the Plastic Surgery Foundation and various surgical organizations, aims to promote innovative research in hand and plastic surgery. With funding of up to $10,000 for one-year pilot projects, this initiative encourages the development of surgeon scientists and seeks to enhance research funding in the field. Eligible applicants must be medical professionals holding relevant positions in U.S. or Canadian institutions.
Reconstructive Surgery

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers aiming to transition to independent faculty positions. It encourages candidates with doctoral degrees in research or clinical fields to apply, particularly those in cancer control and prevention. This funding opportunity facilitates a quick shift from mentored research to independent careers, providing essential support for awardees to establish competitive research programs without leading their own clinical trials.
Medical Education & Professional Training Biology Science +2 more

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Pathway to Independence Award (K99/R00) aims to support early-stage postdoctoral researchers transitioning to independent faculty positions. This initiative focuses on talented individuals with doctoral degrees in research or clinical fields, providing essential NCI funding during this key career juncture. Researchers engaged in cancer control, prevention, and data sciences are encouraged to apply for this opportunity, which emphasizes experimental studies with human participants, thus aligning with NIH's clinical trial definitions.
Biology Science Medical Education & Professional Training +1 more

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports early-stage postdoctoral researchers transitioning to independent faculty positions. This funding opportunity encourages talented individuals with clinical or research doctoral degrees to lead independent clinical trials. Applicants should aim to foster research careers in cancer control, prevention, and data sciences. This initiative provides essential support during the transition from mentored positions to independent research roles, enhancing the pool of independent investigators in cancer research.
Medical Education & Professional Training Biology Science +2 more

Transformation of Mental Health Care Program

Klingenstein Third Generation Foundation
Private
United States
US $200,000
The Klingenstein Third Generation Foundation's 'Transformation of Mental Health Care Program' seeks innovative research into improving mental health care access for children and adolescents, particularly from under-resourced backgrounds. Applications are invited for studies that build on promising pilot work, focusing on scalable delivery models and technology use. Eligible applicants are academic researchers based in the U.S. who can demonstrate rigorous research capabilities. The foundation plans to award up to two grants of $100,000 each year for two years.
Children’s Mental Health

Aging Research Dissertation Awards to Promote Diversity (R36 Clinical Trial Not Allowed) (351006)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $142,312
The Aging Research Dissertation Awards aim to enhance diversity in the scientific workforce by funding research on aging and related health conditions. The program encourages applicants from underrepresented backgrounds to apply for dissertation awards that align with the National Institutes of Health's strategic priorities. Key deadlines for applications include February 16, June 16, and October 16 for the years 2024 through 2026.
Aging / Gerontology

PLTW Launch - New Program- Initiative: PLTW Grant- ( within 50 states of US)

Project Lead The Way Inc
Private
United States
US $4,900 - US $13,900
PLTW Launch offers a rolling grant for schools across the U.S. to implement the PLTW Launch program for the upcoming academic year. All schools, especially those serving low-income and minority populations, are encouraged to apply. The grant covers participation and training fees, with requirements to implement multiple PLTW modules over time. This initiative aims to enhance STEM education, ensuring diverse access to innovative learning opportunities.
STEM / STEAM Education Teacher Development & Training

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (351101)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program supports NCATS CTSA Program KL2 scholars, enhancing their transition to independent academic translational scientists. This R03 funding facilitates various research projects, including pilot studies and methodology development, aimed at generating preliminary data for future R01 applications. The program is designed for short-term projects utilizing limited resources, promoting innovative research in clinical and translational science.
Health & Medicine Biology

HCLTech Grant Edition II

HCL Technologies Limited
Corporate
Argentina, Brazil +8 more
Up to US $500,000
HCLTech Grant Edition II focuses on impactful climate action by investing $5 million over five years to support NGOs in the Americas. This initiative aims to enhance sustainable projects that align with the 17 Sustainable Development Goals (SDGs). With a history of significant contributions in India, HCLTech is committed to achieving net-zero emissions by 2040 and fostering innovative solutions to address pressing climate challenges. The grant encourages collaboration and aims to transform communities through effective climate action.
Climate Change Resilience & Equity

Indian Environmental General Assistance Program

Environmental Protection Agency
Federal Government
United States
Unspecified amount
The Indian Environmental General Assistance Program (GAP), administered by the U.S. Environmental Protection Agency (EPA), provides crucial funding to tribal governments and intertribal consortia for developing environmental protection programs. Since 1992, GAP has focused on remediation of pollutants and, more recently, supports climate adaptation initiatives. The program emphasizes tribal sovereignty while aiding in capacity building, policymaking, and establishing joint EPA-Tribal Environmental Plans to effectively address environmental challenges faced by tribal communities.
Indigenous Sovereignty & Rights Environmental Conservation Waste Management +2 more

SBB Research Group Foundation Grant

SBB Research Group Foundation
Private
United States
US $1,000 - US $5,000
The SBB Research Group Foundation Grant supports 501(c)(3) organizations addressing unmet needs through sustainable strategies. Winners are selected monthly, receiving $5,000, while other finalists are awarded $1,000. The foundation collaborates with various partners and has a strong commitment to community service. Organizations are encouraged to apply early, as prior applicants can be reconsidered in subsequent months. This initiative aims to empower impactful initiatives across diverse sectors.
Community Services

Providing Research Education Experiences to Enhance Inclusivity for a Diverse Substance Use and Addiction Scientific Workforce (R25 Clinical Trials Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The NIH R25 program aims to enhance inclusivity in research education by supporting activities that encourage individuals from diverse backgrounds to pursue careers in substance use and addiction sciences. This initiative focuses on skills development courses and research experiences, particularly targeting underrepresented groups in biomedical and behavioral sciences. Applications are due by 5:00 PM local time of the applicant organization, with optional Letters of Intent encouraged 30 days prior to the full proposal deadline.
Addiction & Substance Use Disorders STEM / STEAM Education Biology +3 more

Allergic Respiratory Diseases Award

American Lung Association
Private
United States
Up to US $150,000
The Allergic Respiratory Diseases Award, supported by the American Lung Association and the American Academy of Allergy, Asthma & Immunology, aims to bolster research in allergic respiratory diseases. Designed for faculty in Clinical Allergy and Immunology at academic medical centers, this award offers $75,000 annually for up to two years. It seeks to empower researchers at pivotal points in their careers, enhancing understanding and treatment of these conditions while promoting lung health.
Respiratory Diseases & Systems Allergies & Allergic Diseases Immune System Diseases

Catalyst Award

American Lung Association
Private
United States
Up to US $100,000
The Catalyst Award, offered by the American Lung Association, supports innovative research on lung disease and biology. This mentored grant provides $50,000 annually for up to two years, prioritizing novel projects with collaborative training plans. The American Lung Association aims to improve lung health and prevent diseases through research, education, and advocacy, focusing on defeating lung cancer and fostering a tobacco-free future.
Lung Cancer Respiratory Diseases & Systems

Dalsemer Interstitial Lung Disease Award

American Lung Association
Private
United States
Up to US $100,000
The Dalsemer Interstitial Lung Disease Award, funded by the American Lung Association, provides $50,000 per year for two years to support junior investigators researching interstitial lung disease. This award aims to foster independence in early-career scientists while building on the Association's 120-year legacy of improving lung health through innovative research and advocacy efforts, ultimately enhancing the lives of those affected by lung disease.
Interstitial Lung Disease

Emerging Respiratory Pathogen Award

American Lung Association
Private
United States
Up to US $200,000
The Emerging Respiratory Pathogen Award, offered by the American Lung Association, aims to enhance our understanding of respiratory infections' pathobiology and their implications. This award supports innovative research addressing the biology of respiratory viruses, host response factors, community spread dynamics of COVID-19, and long-term effects of viral infections. With a funding of $100,000 per year for two years, this initiative encourages groundbreaking studies to improve lung health and disease outcomes.
Respiratory Diseases & Systems Epidemiology & Public Health

Hasting Innovation Award for Interstitial Lung Disease

American Lung Association
Private
United States
Up to US $75,000
The Hasting Innovation Award for Interstitial Lung Disease, offered by the American Lung Association, provides $75,000 annually for up to two years to support early-career researchers. This award targets investigators with proven excellence and a track record of accomplishment, aiming to advance lung disease science. Successful candidates must have held a K or R type award within the last three to five years, fostering innovation and discovery in lung health.
Interstitial Lung Disease

Innovation Award

American Lung Association
Private
United States
Up to US $150,000
The Innovation Award by the American Lung Association offers $75,000 annually for up to two years, aimed at supporting promising investigators in lung disease research. With a legacy of over 120 years, the Association seeks to fund innovative projects that can significantly impact lung health. Eligible candidates must demonstrate prior excellence in their careers and have held a K or R type award within the last three to five years. This initiative fosters groundbreaking advancements in lung disease science.
Lung Cancer Respiratory Diseases & Systems

O'Reilly Automotive Foundation Grant

O'Reilly Automotive Foundation Inc
Private
United States
Unspecified amount
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
Economic Services & Development Homelessness Services Food Access & Hunger +12 more

Stem Cell Grants: Travel Award

Cornell University- Society for the Humanities
Association/Society
United States
Up to US $1,200
The Stem Cell Grants: Travel Award supports students, postdocs, and faculty attending scientific conferences and workshops related to stem cell research. Up to $1,200 is available for each application, with a maximum of two applications per PI lab each calendar year. Priority is given to those presenting at stem cell meetings and workshops. All applications must be submitted at least one week before travel to ensure funding consideration.
Bioengineering Synthetic Biology Cell Biology +4 more

Kyndryl Foundation Grant

Kyndryl Charitable Foundation
Private
Czech Republic, Hungary +5 more
Unspecified amount
The Kyndryl Foundation Grant aims to empower communities through investments in education, technology, and workforce development. With a focus on cybersecurity and AI skills for underrepresented learners, the foundation fosters balanced partnerships and innovation. It prioritizes transparency and integrity, ensuring grants support long-term impact. This initiative aligns with Kyndryl's mission to create a sustainable future by enhancing access to opportunities and resources for all, thereby promoting diversity and inclusivity in economic growth.
Cybersecurity Workforce Preparation & Job Readiness Career / College Preparation +2 more

Norfolk Southern Corporate Giving: Safety First Grant Program

Norfolk Southern Foundation
Corporate
Alabama, Delaware +20 more
US $1,000 - US $15,000
The Norfolk Southern Corporate Giving: Safety First Grant Program aims to enhance community safety across its 22-state network. With grants ranging from $1,000 to $15,000, it supports organizations that provide safety services or promote safe behavior. This program reflects Norfolk Southern's commitment to diversity, equity, and inclusion, empowering employees to engage locally. By investing in safety and workforce development, Norfolk Southern fosters thriving communities, demonstrating its dedication to social responsibility and community well-being.
Community / Public Safety First Responders

Norfolk Southern Corporate Giving: Thriving Communities Grant Program

Norfolk Southern Foundation
Corporate
Alabama, Delaware +20 more
US $1,000 - US $50,000
The Norfolk Southern Corporate Giving: Thriving Communities Grant Program supports initiatives that promote sustainability, workforce development, and community resilience across a 22-state network. With grants ranging from $1,000 to $50,000, the program aims to foster economic development and ensure equal access to basic necessities. Eligible organizations include tax-exempt nonprofits, government entities, and public schools, emphasizing diversity and inclusion in their community-focused efforts.
Sustainability Workforce Preparation & Job Readiness Community Development & Revitalization +2 more

Journalism & Media Grant

John D and Catherine T MacArthur Foundation
Private
United States
Unspecified amount
The Journalism & Media Grant aims to promote inclusive narratives and accurate media that engage communities in democratic processes. It supports U.S.-based nonprofit organizations focused on professional reporting, multimedia storytelling, and civic media. The grant addresses barriers to media participation and fosters innovation in journalism, providing essential infrastructure for a diverse media landscape. While unsolicited proposals are not accepted, organizations can share ideas through a Letter of Inquiry (LOI).
Internet / Media Freedom Journalism News Media & Communications +1 more

American Journalism Project

American Journalism Project Inc
Private
United States
Unspecified amount
The American Journalism Project is dedicated to enhancing local news organizations by investing in their business capacities and providing personalized coaching. They prioritize diversity, equity, and inclusion, encouraging inquiries from organizations serving underrepresented communities. Their approach offers tailored support based on grantees' strategic challenges, fostering sustainable growth in revenue and programming. They seek grantees with strong public-service missions, independent 501(c)(3) status, and a commitment to transparency and accountability in their operations.
Journalism Internet / Media Freedom News Media & Communications

Greenville County Grants for Nonprofits Highlights

Looking for Greenville County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Greenville County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Greenville County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

68 Greenville County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

14 Greenville County grants for nonprofits over $25K in average grant size

13 Greenville County grants for nonprofits over $50K in average grant size

12 Greenville County grants for nonprofits supporting general operating expenses

62 Greenville County grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Greenville County grants for Nonprofits?

Most grants are due in the third quarter.

Q1
24.4%
Q2
22.6%
Q3
30.3%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Greenville County Grants for Nonprofits?

Grants are most commonly $10,000.

$500 $500 Min.
$10,000 $10 K Median
$218,238 $218.2 K Average
$5,000,000 $5 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Greenville County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Greenville County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Greenville County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081